Hybrid nanofilms as topical anesthetics for pain-free procedures in dentistry.

abstract：:A new, efficient method based on a series of matrices is introduced to completely describe the detailed topology of individual domains and their topology evolution in three-dimensional cellular structures. With this approach, we found a lot of new topological grain forms which are never reported before, i.e., there ar...

journal_title：Scientific reports

authors： Xue W,Wang H,Liu G,Meng L,Xiang S,Ma G,Li W

更新日期：2016-05-10 00:00:00

abstract：:Quantitative measurement and analysis of tumor metabolic activities could provide a more optimal solution to personalized accurate dose painting. We collected PET images of 58 lung cancer patients, in which the tumor exhibits heterogeneous FDG uptake. We design an automated delineation and quantitative heterogeneity m...

journal_title：Scientific reports

authors： Wang X,Cui H,Gong G,Fu Z,Zhou J,Gu J,Yin Y,Feng D

更新日期：2018-07-13 00:00:00

abstract：:Vitamin D and parathyroid hormone (PTH) regulate mineral metabolism and are required to maintain calcium levels. Vitamin D deficiency is common, particularly during pregnancy, and has been associated with hypertensive disorders of pregnancy. We sought to determine whether maternal 25(OH)D, PTH and calcium concentratio...

journal_title：Scientific reports

authors： Santorelli G,Whitelaw D,Farrar D,West J,Lawlor DA

更新日期：2019-02-04 00:00:00

abstract：:Experiments were conducted to improve jenny conception rates through induced ovulation and timed insemination. Jennies in control, hCG and LH groups were injected intramuscularly with saline alone or saline containing hCG or LH, respectively, when the dominant follicle diameter reached 35 mm. Then, follicle developmen...

journal_title：Scientific reports

authors： Chang ZL,Li BX,Liu B,Yao L,Yu J,Jiang GM,Tan JH

更新日期：2019-03-01 00:00:00

abstract：:Mesenchymal stromal cells (MSC) are used in cell therapies, however cellular senescence increases heterogeneity of cell populations and leads to uncertainty in therapies' outcomes. The determination of cellular senescence is time consuming and logistically intensive. Here, we propose the use of endogenous autofluoresc...

journal_title：Scientific reports

authors： Bertolo A,Baur M,Guerrero J,Pötzel T,Stoyanov J

更新日期：2019-02-14 00:00:00

abstract：:We have proposed and successfully demonstrated a novel approach to direct conversion of mechanical energy into electrical energy using microfluidics. The method combines previously demonstrated reverse electrowetting on dielectric (REWOD) phenomenon with the fast self-oscillating process of bubble growth and collapse....

journal_title：Scientific reports

authors： Hsu TH,Manakasettharn S,Taylor JA,Krupenkin T

更新日期：2015-11-16 00:00:00

abstract：:Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups often leave child...

journal_title：Scientific reports

authors： Mather RL,Loveson KF,Fillmore HL

更新日期：2019-06-13 00:00:00

abstract：:Direct visualization and assessment of the iridocorneal angle (ICA) region with high resolution is important for the clinical evaluation of glaucoma. However, the current clinical imaging systems for ICA do not provide sufficient structural details due to their poor resolution. The key challenges in achieving high qua...

journal_title：Scientific reports

authors： Perinchery SM,Shinde A,Fu CY,Jeesmond Hong XJ,Baskaran M,Aung T,Murukeshan VM

更新日期：2016-07-29 00:00:00

abstract：:The development of environmentally friendly plant protection products (PPPs), including pesticides, is a challenge nowadays. A commercial herbicide combining terbuthylazine and nicosulfuron as active substances (a.s.) was selected as a model PPP. The suitability of manipulating the ratio between a.s. towards alternati...

journal_title：Scientific reports

authors： Queirós L,Vidal T,Nogueira AJA,Gonçalves FJM,Pereira JL

更新日期：2018-04-03 00:00:00

abstract：:High content of organic matter in the downstream of watersheds underscored the severity of non-point source (NPS) pollution. The major objectives of this study were to characterize and quantify dissolved organic matter (DOM) in watersheds affected by NPS pollution, and to apply self-organizing map (SOM) and parallel f...

journal_title：Scientific reports

authors： Zhang Y,Liang X,Wang Z,Xu L

更新日期：2015-11-03 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Safra L,Ioannou C,Amsellem F,Delorme R,Chevallier C

更新日期：2018-12-21 00:00:00

abstract：:Multifunctional nanocarriers harbouring specific targeting moieties and with pH-responsive properties offer great potential for targeted cancer therapy. Several synthetic drug carriers have been studied extensively as drug delivery systems but not much information is available on the application of virus-like nanopart...

journal_title：Scientific reports

authors： Biabanikhankahdani R,Alitheen NBM,Ho KL,Tan WS

更新日期：2016-11-24 00:00:00

abstract：:Complex regulatory networks control epithelial-to-mesenchymal transition (EMT) but the underlying epigenetic control is poorly understood. Lysine-specific demethylase 1 (LSD1) is a key histone demethylase that alters the epigenetic landscape. Here we explored the role of LSD1 in global epigenetic regulation of EMT, ca...

journal_title：Scientific reports

authors： Boulding T,McCuaig RD,Tan A,Hardy K,Wu F,Dunn J,Kalimutho M,Sutton CR,Forwood JK,Bert AG,Goodall GJ,Malik L,Yip D,Dahlstrom JE,Zafar A,Khanna KK,Rao S

更新日期：2018-01-08 00:00:00

abstract：:We study heat dissipation of a multi-wall carbon nanotube (MWCNT) device fabricated from two crossed nanotubes on a SiNx substrate under the influence of a constant (DC) electric bias. By monitoring the temperature of the substrate, we observe negligible Joule heating within the nanotube lattice itself and instead hea...

journal_title：Scientific reports

authors： Voskanian N,Olsson E,Cumings J

更新日期：2019-07-25 00:00:00

abstract：:Cross-polarization conversion plays an important role in visible light manipulation. Metasurface with asymmetric structure can be used to achieve polarization conversion of linearly polarized light. Based on this, we design a quasi-periodic dendritic metasurface model composed of asymmetric dendritic cells. The simula...

journal_title：Scientific reports

authors： Fang ZH,Chen H,An D,Luo CR,Zhao XP

更新日期：2018-06-26 00:00:00

abstract：:With land privatization and fencing of thousands of hectares of communal grazing areas, East Africa is struggling with one of the most radical cultural and environmental changes in its history. The 668,500-hectare Greater Mara is of crucial importance for the great migrations of large mammals and for Maasai pastoralis...

journal_title：Scientific reports

authors： Løvschal M,Bøcher PK,Pilgaard J,Amoke I,Odingo A,Thuo A,Svenning JC

更新日期：2017-01-25 00:00:00

abstract：:Epigenetic deregulation, such as the reduction of histone acetylation levels, is thought to be causally linked to various maladies associated with aging. Consequently, histone deacetylase inhibitors are suggested to serve as epigenetic therapy by increasing histone acetylation. However, previous work suggests that man...

journal_title：Scientific reports

authors： Becker L,Nogueira MS,Klima C,de Angelis MH,Peleg S

更新日期：2018-03-08 00:00:00

abstract：:Thaumarchaeota and the gene encoding for a subunit of ammonia monooxygenase (amoA) are ubiquitous in Polar Seas, and some Thaumarchaeota also have a gene coding for ureC, diagnostic for urease. Using quantitative PCR we investigated the occurrence of genes and transcripts of ureC and amoA in Arctic samples from winter...

journal_title：Scientific reports

authors： Pedneault E,Galand PE,Potvin M,Tremblay JÉ,Lovejoy C

更新日期：2014-04-11 00:00:00

abstract：:Halobacteria, a class of Euryarchaeota are extremely halophilic archaea that can adapt to a wide range of salt concentration generally from 10% NaCl to saturated salt concentration of 32% NaCl. It consists of the orders: Halobacteriales, Haloferaciales and Natriabales. Pan-genome analysis of class Halobacteria was don...

journal_title：Scientific reports

authors： Gaba S,Kumari A,Medema M,Kaushik R

更新日期：2020-12-03 00:00:00

abstract：:Both CC and CXC-class chemokines drive inflammatory disease. Tick salivary chemokine-binding proteins (CKBPs), or evasins, specifically bind subsets of CC- or CXC-chemokines, and could precisely target disease-relevant chemokines. Here we have used yeast surface display to identify two tick evasins: a CC-CKBP, P1243 f...

journal_title：Scientific reports

authors： Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S

更新日期：2018-04-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Boonma K,Kumar A,Garcia-Castellanos D,Jiménez-Munt I,Fernández M

更新日期：2020-01-15 00:00:00

abstract：:This paper analyzed the compositional and structural changes of humic acid (HA) after combined with phosphate fertilizer (PHA), and investigated its effects on the growth of maize seedlings with four humic acid concentrations. The results showed that the atomic ratios of O/C and (O + N)/N of PHA were significantly low...

journal_title：Scientific reports

authors： Jing J,Zhang S,Yuan L,Li Y,Lin Z,Xiong Q,Zhao B

更新日期：2020-10-15 00:00:00

abstract：:Structural disorder is widespread in eukaryotic proteins and is vital for their function in diverse biological processes. It is therefore highly desirable to be able to predict the degree of order and disorder from amino acid sequence. It is, however, notoriously difficult to predict the degree of local flexibility wi...

journal_title：Scientific reports

authors： Dass R,Mulder FAA,Nielsen JT

更新日期：2020-09-08 00:00:00

abstract：:Sodefrin, a decapeptide isolated from the male dorsal gland of the Japanese fire belly newt Cynops pyrrhogaster, was the first peptide pheromone identified from a vertebrate. The fire belly salamander and sodefrin have become a model for sex pheromone investigation in aquatically courting salamanders ever since. Subse...

journal_title：Scientific reports

authors： Van Bocxlaer I,Maex M,Treer D,Janssenswillen S,Janssens R,Vandebergh W,Proost P,Bossuyt F

更新日期：2016-03-03 00:00:00

abstract：:In recent years methicillin-resistant Staphylococcus aureus has posed a challenge in treating skin and soft tissue infections. Finding new antimicrobial agents has therefore become imperative. We evaluated the in vitro antimicrobial activity of a synthetic peptide, P6, against multidrug resistant clinical strains of S...

journal_title：Scientific reports

authors： Bacalum M,Dragulescu EC,Necula G,Codita I,Radu M

更新日期：2019-11-20 00:00:00

abstract：:The Aspergillus niger-derived prolyl endoprotease (AN-PEP) has previously been shown to degrade gluten in healthy subjects when added to an intragastrically infused meal. The current study investigated the efficacy of AN-PEP in a physiological meal setting. In this randomized placebo-controlled crossover study, 18 glu...

journal_title：Scientific reports

authors： König J,Holster S,Bruins MJ,Brummer RJ

更新日期：2017-10-12 00:00:00

abstract：:Pilonidal sinus disease (PSD) is increasing globally. A recent meta-analysis and merged-data analysis showed that recurrence rates in PSD depend essentially on follow-up time and specific surgical procedures. However, the global distribution of surgical approaches and respective recurrence rates have never been studie...

journal_title：Scientific reports

authors： Doll D,Orlik A,Maier K,Kauf P,Schmid M,Diekmann M,Vogt AP,Stauffer VK,Luedi MM

更新日期：2019-10-22 00:00:00

abstract：:Benign and malignant tumors differ in the viscoelastic properties of their cellular microenvironments and in their spatiotemporal response to very low frequency stimuli. These differences can introduce a unique viscoelastic biomarker in differentiation of benign and malignant tumors. This biomarker may reduce the numb...

journal_title：Scientific reports

authors： Nabavizadeh A,Bayat M,Kumar V,Gregory A,Webb J,Alizad A,Fatemi M

更新日期：2019-04-05 00:00:00

abstract：:This study investigates the association between an index of mesozooplankton biomass, derived from the Continuous Plankton Recorder survey and satellite-derived productivity fronts in the North Atlantic. While chlorophyll-a content (CHL) is commonly described as a proxy for phytoplankton biomass, the size of productivi...

journal_title：Scientific reports

authors： Druon JN,Hélaouët P,Beaugrand G,Fromentin JM,Palialexis A,Hoepffner N

更新日期：2019-03-18 00:00:00

abstract：:Proteins involved in genetic stability maintenance and safeguarding DNA replication act not only against cancer initiation but could also play a major role in sustaining cancer progression. Here, we report that the FANC pathway is highly expressed in metastatic melanoma harboring the oncogenic microphthalmia-associate...

journal_title：Scientific reports

authors： Bourseguin J,Bonet C,Renaud E,Pandiani C,Boncompagni M,Giuliano S,Pawlikowska P,Karmous-Benailly H,Ballotti R,Rosselli F,Bertolotto C

更新日期：2016-11-09 00:00:00