Pan-genome analysis and ancestral state reconstruction of class halobacteria: probability of a new super-order.

abstract：:This paper describes two different electrochemical affinity biosensing approaches for the simple, fast and bisulfite and PCR-free quantification of 5-methylated cytosines (5-mC) in DNA using the anti-5-mC antibody as biorecognition element. One of the biosensing approaches used the anti-5-mC as capture bioreceptor and...

journal_title：Scientific reports

authors： Povedano E,Vargas E,Montiel VR,Torrente-Rodríguez RM,Pedrero M,Barderas R,Segundo-Acosta PS,Peláez-García A,Mendiola M,Hardisson D,Campuzano S,Pingarrón JM

更新日期：2018-04-23 00:00:00

abstract：:The distribution, characteristics of extracellular polymeric substances (EPS) of Phanerochaete chrysosporium under Pb2+ stress and the influence on Pb removal were investigated. Polysaccharides was found to be the main composition in both soluble EPS (SEPS) and bounded EPS (BEPS). More polysaccharides and protein in B...

journal_title：Scientific reports

authors： Li N,Liu J,Yang R,Wu L

更新日期：2020-10-19 00:00:00

abstract：:Surgery and anesthesia induce inflammatory changes in the central nervous system, which ultimately lead to neuronal damage concomitant with an increase in the level of neurodegeneration markers. Despite some experimental data showing prolonged activation of the immune system post-surgery, no study has determined the e...

journal_title：Scientific reports

authors： DiMeglio M,Furey W,Hajj J,Lindekens J,Patel S,Acker M,Bavaria J,Szeto WY,Atluri P,Haber M,Diaz-Arrastia R,Laudanski K

更新日期：2019-05-09 00:00:00

abstract：:It remains unclear how infantile febrile seizures (FS) enhance adult seizure susceptibility. Here we showed that the transient increase of interleukin-1β (IL-1β) after prolonged FS promoted adult seizure susceptibility, which was blocked by interleukin-1 receptor antagonist (IL-1Ra) within a critical time window. Post...

journal_title：Scientific reports

authors： Feng B,Tang Y,Chen B,Xu C,Wang Y,Dai Y,Wu D,Zhu J,Wang S,Zhou Y,Shi L,Hu W,Zhang X,Chen Z

更新日期：2016-02-23 00:00:00

abstract：:Mullite nanowhiskers are prepared by a facile technique at low temperature using mica and AlF3 as raw material. Mica acts as reactant as well as substrate. By controlling the reaction temperature and holding time, the mullite nanowhisker array with uniform morphology is obtained. The nanowhisker array possesses Al-ric...

journal_title：Scientific reports

authors： Yang T,Wang E,Wang F,Chou K,Hou X

更新日期：2015-04-13 00:00:00

abstract：:We present the design and performance characterization of a Faraday laser directly lasing on the Rb 1529 nm transition (Rb, 5P 3/2 - 4D 5/2) with high stability, narrow spectral linewidth and low cost. This system does not need an additional frequency-stabilized pump laser as a prerequisite to preparing Rb atom from 5...

journal_title：Scientific reports

authors： Chang P,Peng H,Zhang S,Chen Z,Luo B,Chen J,Guo H

更新日期：2017-08-21 00:00:00

abstract：:In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intraocular pressures ar...

journal_title：Scientific reports

authors： Hasegawa T,Ikeda HO,Iwai S,Sasaoka N,Kakizuka A,Tsujikawa A

更新日期：2020-12-10 00:00:00

abstract：:Density functional theory predictions have been combined with the microwave-plasma chemical vapor deposition technique to explore metastable synthesis of boron-rich boron-carbide materials. A thin film synthesis of high-hardness (up to 37 GPa) B50C2 via chemical vapor deposition was achieved. Characterization of the e...

journal_title：Scientific reports

authors： Baker PA,Chen WC,Chen CC,Catledge SA,Vohra YK

更新日期：2020-03-10 00:00:00

abstract：:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. ...

journal_title：Scientific reports

authors： Isaacs AT,Lynd A,Donnelly MJ

更新日期：2017-04-25 00:00:00

abstract：:Upper urinary tract urothelial carcinomas are usually managed by radical nephroureterectomy (RNU), often followed by intravesical chemotherapy to minimize recurrence. Open surgery is the gold standard procedure for RNU, but it associates with high morbidity, and it has been increasingly replaced by minimally invasive ...

journal_title：Scientific reports

authors： Oliveira C,Barros AA,Reis RL,Correia-Pinto J,Lima E

更新日期：2019-12-10 00:00:00

abstract：:A key to the success of chimeric antigen receptor (CAR) T-cell based therapies greatly rely on the capacity to identify and target antigens with expression restrained to tumor cells. Here we present a strategy to generate CAR T-cells that are only effective locally (tumor tissue), potentially also increasing the choic...

journal_title：Scientific reports

authors： Juillerat A,Marechal A,Filhol JM,Valogne Y,Valton J,Duclert A,Duchateau P,Poirot L

更新日期：2017-01-20 00:00:00

abstract：:Activated sludge granules and flocs have their inherent advantages and disadvantages for wastewater treatment due to their different characteristics. So far quantitative information on their evaluation is still lacking. This work provides a quantitative and comparative evaluation on the characteristics and pollutant r...

journal_title：Scientific reports

authors： Fang F,Qiao LL,Ni BJ,Cao JS,Yu HQ

更新日期：2017-02-17 00:00:00

abstract：:A bound state in the continuum (BIC) is an unusual localized state that is embedded in a continuum of extended states. Here, we present the general condition for BICs to arise from wave equation separability. Then we show that by exploiting perturbations of certain symmetry such BICs can be turned into resonances that...

journal_title：Scientific reports

authors： Rivera N,Hsu CW,Zhen B,Buljan H,Joannopoulos JD,Soljačić M

更新日期：2016-09-19 00:00:00

abstract：:Regret results from comparing non-optimal outcomes containing both gain and loss parts to better alternatives during decision-making. The present fMRI study aimed to explore whether levels of regret could change when gain or loss part of a non-optimal outcome was focused during a sequential risk taking task, i.e. the ...

journal_title：Scientific reports

authors： Liu Z,Li L,Zheng L,Xu M,Zhou FA,Guo X

更新日期：2017-02-01 00:00:00

abstract：:Despite recent advances in melanoma treatment, metastasis and resistance to therapy remain serious clinical challenges. NME1 is a metastasis suppressor, a class of proteins which inhibits metastatic spread of cancer cells without impact on growth of the primary tumor. We have identified a rare subpopulation of cells w...

journal_title：Scientific reports

authors： Snyder D,Wang Y,Kaetzel DM

更新日期：2020-02-06 00:00:00

abstract：:The development of metal-based agents has had a tremendous role in the present progress in cancer chemotherapy. One well-known example of metal-based agents is Schiff based metal complexes, which hold great promise for cancer therapy. Based on the potential of Schiff based complexes for the induction of apoptosis, thi...

journal_title：Scientific reports

authors： Hajrezaie M,Paydar M,Looi CY,Moghadamtousi SZ,Hassandarvish P,Salga MS,Karimian H,Shams K,Zahedifard M,Majid NA,Ali HM,Abdulla MA

更新日期：2015-03-13 00:00:00

abstract：:In order to screen out an effective bone loss protectant from natural plant polyphenol and to elucidate the mechanism of the plant polyphenols that alleviate bone loss under simulated microgravity, the proliferation activities of 9 total polyphenol extracts from natural product (TPENP) on osteoblasts were measured. Po...

journal_title：Scientific reports

authors： Diao Y,Chen B,Wei L,Wang Z

更新日期：2018-08-24 00:00:00

abstract：:The Glycoside hydrolase (GH) family 70 originally was established for glucansucrases of lactic acid bacteria (LAB) converting sucrose into α-glucan polymers. In recent years we have identified 3 subfamilies of GH70 enzymes (designated GtfB, GtfC and GtfD) as 4,6-α-glucanotransferases, cleaving (α1 → 4)-linkages in mal...

journal_title：Scientific reports

authors： Gangoiti J,van Leeuwen SS,Meng X,Duboux S,Vafiadi C,Pijning T,Dijkhuizen L

更新日期：2017-08-30 00:00:00

abstract：:Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol exposure and withdrawal from chronic ethanol exposure on glymphatic function, which is a brain-wide metabolite clearance system connected ...

journal_title：Scientific reports

authors： Lundgaard I,Wang W,Eberhardt A,Vinitsky HS,Reeves BC,Peng S,Lou N,Hussain R,Nedergaard M

更新日期：2018-02-02 00:00:00

abstract：:Many environmental flow (e-flow) studies and applications have predominantly used state-(i.e., at a single time point) and rate-(i.e., temporal change) based demographic characteristics of species representing lower trophic levels (e.g., fish communities) to build flow-ecology relationships, rather than using a proces...

journal_title：Scientific reports

authors： Paudel S,Koprowski JL,Thakuri U,Sigdel R,Gautam RC

更新日期：2020-12-18 00:00:00

abstract：:Human enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the major etiological agents of hand, foot and mouth disease (HFMD) and are often associated with neurological complications. Currently, several vaccine types are being developed for EV71 and CA16. In this study, we constructed a bivalent chimeric virus-lik...

journal_title：Scientific reports

authors： Xu L,He D,Yang L,Li Z,Ye X,Yu H,Zhao H,Li S,Yuan L,Qian H,Que Y,Kuo Shih JW,Zhu H,Li Y,Cheng T,Xia N

更新日期：2015-08-05 00:00:00

abstract：:Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not i...

journal_title：Scientific reports

authors： Priyadarshi S,Harohally NV,Roopavathi C,Naidu MM

更新日期：2018-11-27 00:00:00

abstract：:Hand, foot, and mouth disease (HFMD), predominantly occurs among infants and children. Previous studies have shown that suitable, stable temperatures favor HFMD virus reproduction; however, temperature fluctuations also affect virus transmission, and there are, so far, no studies concerning the association between suc...

journal_title：Scientific reports

authors： Xu C,Zhang X,Wang L,Zhou Y,Xiao G,Liao J

更新日期：2020-02-13 00:00:00

abstract：:The most consistent sex differences in cognition are found for spatial ability, in which males, on average, outperform females. Utilizing a twin design, two studies have shown that females with male co-twins perform better than females with female co-twins on a mental rotation task. According to the Twin Testosterone ...

journal_title：Scientific reports

authors： Toivainen T,Pannini G,Papageorgiou KA,Malanchini M,Rimfeld K,Shakeshaft N,Kovas Y

更新日期：2018-09-12 00:00:00

abstract：:Solving the crystal structure of Cbl(TKB) in complex with a pentapeptide, pYTPEP, revealed that the PEP region adopted a poly-L-proline type II (PPII) helix. An unnatural amino acid termed a proline-templated glutamic acid (ptE) that constrained both the backbone and sidechain to the bound conformation was synthesized...

journal_title：Scientific reports

authors： Kumar EA,Chen Q,Kizhake S,Kolar C,Kang M,Chang CE,Borgstahl GE,Natarajan A

更新日期：2013-01-01 00:00:00

abstract：:Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodeficient mice reconstitu...

journal_title：Scientific reports

authors： Gunawan M,Her Z,Liu M,Tan SY,Chan XY,Tan WWS,Dharmaraaja S,Fan Y,Ong CB,Loh E,Chang KTE,Tan TC,Chan JKY,Chen Q

更新日期：2017-11-30 00:00:00

abstract：:Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a series of enzyme active sites. Many domains from the multimodular PKS that generates the toxin mycolactone display an unusually hi...

journal_title：Scientific reports

authors： Moretto L,Heylen R,Holroyd N,Vance S,Broadhurst RW

更新日期：2019-02-20 00:00:00

abstract：:The occurrence of toxic metals in the aquatic environment is as caused by a variety of contaminations which makes difficulty in the concentration prediction. In this study, conventional methods of back-propagation neural network (BPNN) and nonlinear autoregressive network with exogenous inputs (NARX) were applied as b...

journal_title：Scientific reports

authors： Li P,Hua P,Gui D,Niu J,Pei P,Zhang J,Krebs P

更新日期：2020-08-10 00:00:00

abstract：:Free standing, atomically thin transition metal dichalcogenides are a new class of ultralightweight nanoelectromechanical systems with potentially game-changing electro- and opto-mechanical properties, however, the energy dissipation pathways that fundamentally limit the performance of these systems is still poorly un...

journal_title：Scientific reports

authors： Matis BR,Houston BH,Baldwin JW

更新日期：2017-07-18 00:00:00

abstract：:Kashin-Beck disease (KBD) is a chronic osteoarthropathy, which manifests as joint deformities and growth retardation. Only a few genetic studies of growth retardation associated with the KBD have been carried out by now. In this study, we conducted a two-stage bivariate genome-wide association study (BGWAS) of the KBD...

journal_title：Scientific reports

authors： Hao J,Wang W,Wen Y,Xiao X,He A,Guo X,Yang T,Liu X,Shen H,Chen X,Tian Q,Deng HW,Zhang F

更新日期：2016-08-22 00:00:00