A novel approach combining self-organizing map and parallel factor analysis for monitoring water quality of watersheds under non-point source pollution.

abstract：:Despite dedicated research has been carried out to adequately map the distribution of the sperm whale in the Mediterranean Sea, unlike other regions of the world, the species population status is still presently uncertain. The analysis of two years of continuous acoustic data provided by the ANTARES neutrino telescope...

journal_title：Scientific reports

authors： André M,Caballé A,van der Schaar M,Solsona A,Houégnigan L,Zaugg S,Sánchez AM,Castell JV,Solé M,Vila F,Djokic D,Adrián-Martínez S,Albert A,Anghinolfi M,Anton G,Ardid M,Aubert JJ,Avgitas T,Baret B,Barrios-Martí J,Ba

更新日期：2017-04-12 00:00:00

abstract：:Most ice polymorphs have order-disorder "pairs" in terms of hydrogen positions, which contributes to the rich variety of ice polymorphs; in fact, three recently discovered polymorphs- ices XIII, XIV, and XV-are ordered counter forms to already identified disordered phases. Despite the considerable effort to understand...

journal_title：Scientific reports

authors： Komatsu K,Noritake F,Machida S,Sano-Furukawa A,Hattori T,Yamane R,Kagi H

更新日期：2016-07-04 00:00:00

abstract：:Huntington's disease (HD) is a neurodegenerative disorder whose major symptoms include progressive motor and cognitive dysfunction. Cognitive decline is a critical quality of life concern for HD patients and families. The enzyme histone deacetylase 3 (HDAC3) appears to be important in HD pathology by negatively regula...

journal_title：Scientific reports

authors： Suelves N,Kirkham-McCarthy L,Lahue RS,Ginés S

更新日期：2017-07-20 00:00:00

abstract：:microRNAs (miRNAs) are small double stranded RNA molecules consisting of two complementary strands called the 5p and 3p arms. Following imprecise processing and/or addition of nucleotides at the ends, miRNA biogenesis can give rise to variants called isomiRs. Exosomes are small vesicles released by cells. They have at...

journal_title：Scientific reports

authors： Karlsen TA,Aae TF,Brinchmann JE

更新日期：2019-12-27 00:00:00

abstract：:Corals access inorganic seawater nutrients through their autotrophic endosymbiotic dinoflagellates, but also capture planktonic prey through heterotrophic feeding. Correlating NanoSIMS and TEM imaging, we visualized and quantified the subcellular fate of autotrophic and heterotrophic C and N in the coral Stylophora pi...

journal_title：Scientific reports

authors： Krueger T,Bodin J,Horwitz N,Loussert-Fonta C,Sakr A,Escrig S,Fine M,Meibom A

更新日期：2018-08-23 00:00:00

abstract：:Natural variability in pH in the diffusive boundary layer (DBL), the discrete layer of seawater between bulk seawater and the outer surface of organisms, could be an important factor determining the response of corals and coralline algae to ocean acidification (OA). Here, two corals with different morphologies and one...

journal_title：Scientific reports

authors： Comeau S,Cornwall CE,Pupier CA,DeCarlo TM,Alessi C,Trehern R,McCulloch MT

更新日期：2019-09-06 00:00:00

abstract：:The critical role of the regulatory elements at the 5' end of the HIV-1 genome in controlling the life cycle of HIV-1 indicates that this region significantly influences virus fitness and its biological properties. In this study, we performed a detailed characterization of strain-specific variability of sequences from...

journal_title：Scientific reports

authors： Mbondji-Wonje C,Dong M,Zhao J,Wang X,Nanfack A,Ragupathy V,Sanchez AM,Denny TN,Hewlett I

更新日期：2020-08-06 00:00:00

abstract：:Dysfunction of cortical GABAergic interneurons are involved in numerous neurological disorders including epilepsy, schizophrenia and autism; and replenishment of these cells by transplantation strategy has proven to be a feasible and effective method to help revert the symptoms in several animal models. To develop met...

journal_title：Scientific reports

authors： Wang Q,Hong P,Gao H,Chen Y,Yang Q,Jiang M,Li H

更新日期：2016-01-11 00:00:00

abstract：:Circulating tumor cells (CTCs) are important clinical indicators for prognosis and treatment efficacy. However, CTC investigation is hampered by their low number, making the establishment of permanent CTC lines very challenging. We derived and characterized nine CTC lines using blood samples from a patient with metast...

journal_title：Scientific reports

authors： Soler A,Cayrefourcq L,Mazard T,Babayan A,Lamy PJ,Assou S,Assenat E,Pantel K,Alix-Panabières C

更新日期：2018-10-29 00:00:00

abstract：:Aging is a multifactorial process that results in progressive loss of regenerative capacity and tissue function while simultaneously favoring the development of a large array of age-related diseases. Evidence suggests that the accumulation of senescent cells in tissue promotes both normal and pathological aging. Oxic ...

journal_title：Scientific reports

authors： Ottaviani A,Eid R,Zoccola D,Pousse M,Dubal JM,Barajas E,Jamet K,Lebrigand K,Lapébie P,Baudoin C,Giraud-Panis MJ,Rouan A,Beauchef G,Guéré C,Vié K,Barbry P,Tambutté S,Gilson E,Allemand D

更新日期：2020-11-17 00:00:00

abstract：:We study the electronic structure and lattice dynamics in the ferromagnet MnBi using first-principles calculations and a tight-binding model. The band structure around the Fermi level is dominated by Bi-p states which are the primary contributors to the magnetic anisotropy energy in the low temperature structure. A ti...

journal_title：Scientific reports

authors： Shanavas KV,Parker D,Singh DJ

更新日期：2014-11-27 00:00:00

abstract：:Heat shock protein 90 (HSP90) inhibition is an attractive strategy for cancer treatment. Several HSP90 inhibitors have shown promising effects in clinical oncology trials. However, little is known about HSP90 inhibition-mediated bladder cancer therapy. Here, we report a quantitative proteomic study that evaluates alte...

journal_title：Scientific reports

authors： Li QQ,Hao JJ,Zhang Z,Krane LS,Hammerich KH,Sanford T,Trepel JB,Neckers L,Agarwal PK

更新日期：2017-03-15 00:00:00

abstract：:Toll-like receptors (TLRs) play a key role in innate and adaptive immunity, protecting the host from viral pathogens. We studied the effect of TLR7 polymorphisms on disease susceptibility and progression of chronic hepatitis B (CHB) infection in Chinese adults. Blood samples were taken from 612 patients with confirmed...

journal_title：Scientific reports

authors： Zhu J,Zhang T,Cao L,Li A,Zheng K,Zhang N,Su B,Chen Z,Chen N,Wu H,He Q

更新日期：2017-09-29 00:00:00

abstract：:Aneuploidy has been reported to occur at remarkably high levels in normal somatic tissues using Fluorescence In Situ Hybridization (FISH). Recently, these reports were contradicted by single-cell low-coverage whole genome sequencing (scL-WGS) analyses, which showed aneuploidy frequencies at least an order of magnitude...

journal_title：Scientific reports

authors： Andriani GA,Maggi E,Piqué D,Zimmerman SE,Lee M,Quispe-Tintaya W,Maslov A,Campisi J,Vijg J,Mar JC,Montagna C

更新日期：2019-07-19 00:00:00

abstract：:Photodynamic therapy (PDT), wherein light sensitive non-toxic agents are locally and selectively activated using light, has emerged as an appealing alternative to traditional cancer chemotherapy. Yet to date, PDT efficacy has been mostly characterized using 2D cultures. Compared to 2D cultures, 3D sphere culture gener...

journal_title：Scientific reports

authors： Chen YC,Lou X,Zhang Z,Ingram P,Yoon E

更新日期：2015-07-08 00:00:00

abstract：:Restenosis remains a significant problem after angioplasty of hemodialysis vascular access. Both experimental and clinical studies have shown a protective effect of antioxidants against post-angioplasty restenosis. A prospective, randomized, feasibility study was conducted to investigate the effect of ascorbic acid to...

journal_title：Scientific reports

authors： Yang CW,Wu CC,Luo CM,Chuang SY,Chen CH,Shen YF,Tarng DC

更新日期：2019-07-31 00:00:00

abstract：:Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is used as a first-line treatment for advanced non-small cell lung cancer (NSCLC). However, most NSCLC patients inevitably develop gefitinib resistance, and the mechanisms underlying this resistance are not fully understood. In this study...

journal_title：Scientific reports

authors： Cao X,Lai S,Hu F,Li G,Wang G,Luo X,Fu X,Hu J

更新日期：2017-06-07 00:00:00

abstract：:Superconductivity within layered crystal structures has attracted sustained interest among condensed matter community, primarily due to their exotic superconducting properties. EuBiS2F is a newly discovered member in the BiS2-based superconducting family, which shows superconductivity at 0.3 K without extrinsic doping...

journal_title：Scientific reports

authors： Cheng J,Zhai H,Wang Y,Xu W,Liu S,Cao G

更新日期：2016-11-22 00:00:00

abstract：:Diatoms are among the most diverse eukaryotic microorganisms on Earth, they are responsible for a large fraction of primary production in the oceans and can be found in different habitats. Pseudo-nitzschia are marine planktonic diatoms responsible for blooms in coastal and oceanic waters. We analyzed the transcriptome...

journal_title：Scientific reports

authors： Di Dato V,Musacchia F,Petrosino G,Patil S,Montresor M,Sanges R,Ferrante MI

更新日期：2015-07-20 00:00:00

abstract：:Medium chain fatty acids can activate the pro-inflammatory receptor GPR84 but so also can molecules related to 3,3'-diindolylmethane. 3,3'-Diindolylmethane and decanoic acid acted as strong positive allosteric modulators of the function of each other and analysis showed the affinity of 3,3'-diindolylmethane to be at l...

journal_title：Scientific reports

authors： Mahmud ZA,Jenkins L,Ulven T,Labéguère F,Gosmini R,De Vos S,Hudson BD,Tikhonova IG,Milligan G

更新日期：2017-12-20 00:00:00

abstract：:In this paper, we present a strategy to improve delivery of femtosecond laser pulses from a regenerative amplifier through a hollow core photonic crystal fiber for temporally focused wide-field two-photon endomicroscopy. For endomicroscope application, wide-field two-photon excitation has the advantage of requiring no...

journal_title：Scientific reports

authors： Choi H,So PT

更新日期：2014-10-15 00:00:00

abstract：:Antimicrobial peptides (AMPs) represent a promising class of novel antimicrobial agents owing to their potent antimicrobial activity. In this study, two lead peptides from unrelated classes of AMPs were systematically hybridized into a series of five hybrid peptides (DM1-DM5) with conserved N- and C-termini. This appr...

journal_title：Scientific reports

authors： Le CF,Yusof MY,Hassan H,Sekaran SD

更新日期：2015-05-18 00:00:00

abstract：:Here we report an ABA triblock copolymer that can express microscopic autonomous formation and break-up of aggregates under constant condition to generate macroscopic viscoelastic self-oscillation of the solution. The ABA triblock copolymer is designed to have hydrophilic B segment and self-oscillating A segment at th...

journal_title：Scientific reports

authors： Onoda M,Ueki T,Shibayama M,Yoshida R

更新日期：2015-10-29 00:00:00

abstract：:Bacterial proteins exported to the cell surface play key cellular functions. However, despite the interest to study the localisation of surface proteins such as adhesins, transporters or hydrolases, monitoring their dynamics in live imaging remains challenging, due to the limited availability of fluorescent probes rem...

journal_title：Scientific reports

authors： Chekli Y,Peron-Cane C,Dell'Arciprete D,Allemand JF,Li C,Ghigo JM,Gautier A,Lebreton A,Desprat N,Beloin C

更新日期：2020-09-25 00:00:00

abstract：:The uncertainty relation is a fundamental limit in quantum mechanics and is of great importance to quantum information processing as it relates to quantum precision measurement. Due to interactions with the surrounding environment, a quantum system will unavoidably suffer from decoherence. Here, we investigate the dyn...

journal_title：Scientific reports

authors： Wang D,Huang AJ,Hoehn RD,Ming F,Sun WY,Shi JD,Ye L,Kais S

更新日期：2017-04-21 00:00:00

abstract：:Common features of immune-metabolic and inflammatory diseases such as metabolic syndrome, diabetes, obesity and cardiovascular diseases are an altered gut microbiota composition and a systemic pro-inflammatory state. We demonstrate that active immunization against the outer membrane protein of bacteria present in the ...

journal_title：Scientific reports

authors： Saita D,Ferrarese R,Foglieni C,Esposito A,Canu T,Perani L,Ceresola ER,Visconti L,Burioni R,Clementi M,Canducci F

更新日期：2016-07-07 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) genera...

journal_title：Scientific reports

authors： Willumsen N,Ali SM,Leitzel K,Drabick JJ,Yee N,Polimera HV,Nagabhairu V,Krecko L,Ali A,Maddukuri A,Moku P,Ali A,Poulose J,Menon H,Pancholy N,Costa L,Karsdal MA,Lipton A

更新日期：2019-12-24 00:00:00

abstract：:Visual evoked potential-based brain-computer interfaces (BCIs) have been widely investigated because of their easy system configuration and high information transfer rate (ITR). However, the uncomfortable flicker or brightness modulation of existing methods restricts the practical interactivity of BCI applications. In...

journal_title：Scientific reports

authors： Han C,Xu G,Xie J,Chen C,Zhang S

更新日期：2018-04-11 00:00:00

abstract：:The extracellular matrix (ECM) impacts stem cell differentiation, but identifying formulations supportive of differentiation is challenging in 3D models. Prior efforts involving combinatorial ECM arrays seemed intuitively advantageous. We propose an alternative that suggests reducing sample size and technological burd...

journal_title：Scientific reports

authors： Jung JP,Hu D,Domian IJ,Ogle BM

更新日期：2015-12-21 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is one of the most common inflammatory diseases resulting from habitual smoking. Impaired clearance of apoptotic cell by airway macrophages contributes to lung inflammation. Milk fat globule-EGF factor 8 (MFG-E8), as a link between apoptotic cells and phagocytes, facilitate...

journal_title：Scientific reports

authors： Wang Y,Luo G,Chen J,Jiang R,Zhu J,Hu N,Huang W,Cheng G,Jia M,Su B,Zhang N,Cui T

更新日期：2017-02-14 00:00:00