Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.

abstract：:The natural alkaloid berberine has several pharmacological properties and recently received attention as a potential anticancer agent. In this work, we investigated the molecular mechanisms underlying the anti-tumor effect of berberine on glioblastoma U343 and pancreatic carcinoma MIA PaCa-2 cells. Human dermal fibrob...

journal_title：Scientific reports

authors： Agnarelli A,Natali M,Garcia-Gil M,Pesi R,Tozzi MG,Ippolito C,Bernardini N,Vignali R,Batistoni R,Bianucci AM,Marracci S

更新日期：2018-07-13 00:00:00

abstract：:Breast cancer survivors display altered inflammatory responses to immune challenges relative to cancer-naive controls likely due to previous cancer treatments, stress associated with cancer, and/or tumor physiology. Proper inflammatory responses are necessary for adaptive sickness behaviors (e.g., fatigue, anorexia, a...

journal_title：Scientific reports

authors： Santos JC,Bever SR,Pereira-da-Silva G,Pyter LM

更新日期：2019-01-24 00:00:00

abstract：:Social information use has well-known fitness benefits. However, causes underlying the apparent inter-individual variability in the propensity to use social information are poorly studied. Melanins are pigments responsible for most of intra-specific color variation in vertebrates and their variation is often associate...

journal_title：Scientific reports

authors： Parejo D,Avilés JM

更新日期：2020-02-05 00:00:00

abstract：:The inactivation of pathogens in liquids has broad applications, ranging from water disinfection to food pasteurization. However, common cell inactivation methods (e.g., chlorination, ultraviolet radiation and thermal treatment) have significant drawbacks such as carcinogenic byproduct formation, energy intensiveness ...

journal_title：Scientific reports

authors： Huo ZY,Li GQ,Yu T,Feng C,Lu Y,Wu YH,Yu C,Xie X,Hu HY

更新日期：2018-10-25 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Hassan R,Tantawy M,Gouda NA,Elzayat MG,Gabra S,Nabih A,Diab AA,El-Hadidi M,Bakry U,Shoeb MR,Elanany M,Shalaby L,Sayed AA

更新日期：2020-04-29 00:00:00

abstract：:Posttraumatic growth (PTG) is defined as positive psychological change in the wake of highly challenging circumstances. Healthcare workers in particular are more vulnerable to stressors and trauma than the general population. The current study examined the use and effectiveness of a novel positive psychological interv...

journal_title：Scientific reports

authors： Xu X,Hu ML,Song Y,Lu ZX,Chen YQ,Wu DX,Xiao T

更新日期：2016-12-20 00:00:00

abstract：:The authors present the preparation procedure and a computational model of a three-layered fibrous scaffold for prolonged drug release. The scaffold, produced by emulsion/sequential electrospinning, consists of a poly(D,L-lactic-co-glycolic acid) (PLGA) fiber layer sandwiched between two poly(ε-caprolactone) (PCL) lay...

journal_title：Scientific reports

authors： Milosevic M,Stojanovic DB,Simic V,Grkovic M,Bjelovic M,Uskokovic PS,Kojic M

更新日期：2020-07-07 00:00:00

abstract：:Damage of enteric neurons and partial or total loss of selective neuronal populations are reported in intestinal disorders including inflammatory bowel diseases and necrotizing enterocolitis. To develop three-dimensional scaffolds for enteric neurons we propose the decoration of ionic-complementary self-assembling pep...

journal_title：Scientific reports

authors： Brun P,Zamuner A,Peretti A,Conti J,Messina GML,Marletta G,Dettin M

更新日期：2019-04-03 00:00:00

abstract：:TBX5 is a T-box family transcription factor that regulates heart and forelimb development in vertebrates and functional deficiencies in this protein result in Holt-Oram syndrome. Recently, we have shown that acetylation of TBX5 potentiates its activity and is important for heart and limb development. Here we report th...

journal_title：Scientific reports

authors： Ghosh TK,Aparicio-Sánchez JJ,Buxton S,Brook JD

更新日期：2019-11-29 00:00:00

abstract：:Maintaining vigilance over long periods of time is especially critical in performing fundamental everyday activities and highly responsible professional tasks (e.g., driving, performing surgery or piloting). Here, we investigated the role of aerobic fitness as a crucial factor related to the vigilance capacity. To thi...

journal_title：Scientific reports

authors： Luque-Casado A,Perakakis P,Ciria LF,Sanabria D

更新日期：2016-06-08 00:00:00

abstract：:The coherent state preparation and control of single quantum systems is an important prerequisite for the implementation of functional quantum devices. Prominent examples for such systems are semiconductor quantum dots, which exhibit a fine structure split single exciton state and a V-type three level structure, given...

journal_title：Scientific reports

authors： Mantei D,Förstner J,Gordon S,Leier YA,Rai AK,Reuter D,Wieck AD,Zrenner A

更新日期：2015-05-22 00:00:00

abstract：:Wrightia tinctoria is a constituent of several ayurvedic preparations against skin disorders including psoriasis and herpes, though not yet has been explored for anticancer potential. Herein, for the first time, we report the significant anticancer properties of a semi-purified fraction, DW-F5, from the dichloromethan...

journal_title：Scientific reports

authors： Antony J,Saikia M,Vinod V,Nath LR,Katiki MR,Murty MS,Paul A,Shabna A,Chandran H,Joseph SM,Nishanth KS,Panakkal EJ,Sriramya I,Sridivya I,Ran S,Sankar S,Rajan E,Anto RJ

更新日期：2015-06-10 00:00:00

abstract：:Classical swine fever virus (CSFV) non-structural protein 3 (NS3) is a multifunctional non-structural protein that plays a major role in viral replication. However, how exactly NS3 exerts these functions remains unknown. Here, we identified tumour necrosis factor receptor-associated factor 6 (TRAF6) as a novel NS3-int...

journal_title：Scientific reports

authors： Lv H,Dong W,Cao Z,Li X,Wang J,Qian G,Lv Q,Wang C,Guo K,Zhang Y

更新日期：2017-07-27 00:00:00

abstract：:We established in vivo and in vitro models to investigate the role of αB-Crystallin (CryAB) and assess the ability of aspirin (ASA) to protect the myocardium during prolonged heat stress. Thirty-day-old chickens were divided into three groups (n = 90): heat stress (HS, 40±1 °C); ASA(-)HS(+), 1 mg/kg ASA orally 2 h bef...

journal_title：Scientific reports

authors： Tang S,Yin B,Song E,Chen H,Cheng Y,Zhang X,Bao E,Hartung J

更新日期：2016-11-18 00:00:00

abstract：:The immune system is constantly challenged, being required to protect the organism against a wide variety of infectious pathogens and, at the same time, to avoid autoimmune disorders. One of the most important molecules involved in these events is the Major Histocompatibility Complex class I (MHC-I), responsible for b...

journal_title：Scientific reports

authors： Rigo MM,Antunes DA,Vaz de Freitas M,Fabiano de Almeida Mendes M,Meira L,Sinigaglia M,Vieira GF

更新日期：2015-12-17 00:00:00

abstract：:Solid state memory and switching devices aimed at replacing the flash memory technology operate by switching from the high to low resistance when conductive filaments are created in response to the electric pulse. The filaments are identified with either structurally different protrusions or purely electronic conducti...

journal_title：Scientific reports

authors： Karpov VG,Niraula D

更新日期：2018-08-15 00:00:00

abstract：:Afforestation is an important approach to mitigate global warming. Its complex interactions with the climate system, however, makes it controversial. Afforestation is expected to be effective in the tropics where biogeochemical and biogeophysical effects act in concert; however, its potential in the large semi-arid re...

journal_title：Scientific reports

authors： Yosef G,Walko R,Avisar R,Tatarinov F,Rotenberg E,Yakir D

更新日期：2018-01-17 00:00:00

abstract：:The Southern Ocean has taken up more than 40% of the total anthropogenic carbon (Cant) stored in the oceans since the preindustrial era, mainly in subantarctic mode and intermediate waters (SAMW-AAIW). However, the physical mechanisms responsible for the transfer of Cant into the ocean interior remain poorly understoo...

journal_title：Scientific reports

authors： Langlais CE,Lenton A,Matear R,Monselesan D,Legresy B,Cougnon E,Rintoul S

更新日期：2017-12-06 00:00:00

abstract：:Effects of fertilisation and other management techniques on a weed community were evaluated during wheat growth in a rice-wheat cropping system. Fertiliser treatments were C0 (C means chemical, C0 means zero chemical fertiliser.), CN (N fertiliser), CNK (N plus K fertiliser), CNPK (N plus P and K fertiliser), CNP (N p...

journal_title：Scientific reports

authors： Jiang M,Liu T,Huang N,Shen X,Shen M,Dai Q

更新日期：2018-03-05 00:00:00

abstract：:Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in the autophagic process remains controversial. Furthermore, the mechanis...

journal_title：Scientific reports

authors： Hou B,Wang G,Gao Q,Wei Y,Zhang C,Wang Y,Huo Y,Yang H,Jiang X,Xi Z

更新日期：2019-07-31 00:00:00

abstract：:Screening programs for lung cancer aim to allow diagnosis at the early stage, and therefore the decline in mortality rates. Thus, the aim of this retrospective cohort study was to the comparison of screened and non-screened lung cancer in terms of lung cancer characteristics, overdiagnosis and survival rate. A retrosp...

journal_title：Scientific reports

authors： Wu FZ,Kuo PL,Huang YL,Tang EK,Chen CS,Wu MT,Lin YP

更新日期：2019-12-18 00:00:00

abstract：:Application of alginate-microencapsulated therapeutic cells is a promising approach for diseases that require a local and constant supply of therapeutic molecules. However most conventional alginate microencapsulation systems are associated with low mechanical stability and protrusion of cells which is associated with...

journal_title：Scientific reports

authors： Bhujbal SV,de Haan B,Niclou SP,de Vos P

更新日期：2014-10-31 00:00:00

abstract：:Aerosol particles emitted from various human activities deteriorate air quality and are suggested to increase public health risk. Numerous studies have emphasized the relationship between the mass and/or number concentration of aerosols (or commonly known as particulate matter (PM)) in the atmosphere and the incidence...

journal_title：Scientific reports

authors： Ching J,Kajino M

更新日期：2018-06-11 00:00:00

abstract：:Exposure to an adverse early-life environment leads to long-term health problems, many of which are recapitulated in subsequent generations. The female reproductive tract is particularly sensitive to early-life influences, and plays a pivotal role in programming the conceptus. We examine the influence of suboptimal gr...

journal_title：Scientific reports

authors： Aiken CE,Tarry-Adkins JL,Ozanne SE

更新日期：2015-11-03 00:00:00

abstract：:Cholestasis impairs liver regeneration following partial liver resection (PHx). Bile acid receptor farnesoid X-receptor (FXR) is a key mediator of liver regeneration. The effects of FXR agonist obeticholic acid (OCA) on liver (re)growth were therefore studied in cholestatic rats. Animals underwent sham surgery or reve...

journal_title：Scientific reports

authors： van Golen RF,Olthof PB,Lionarons DA,Reiniers MJ,Alles LK,Uz Z,de Haan L,Ergin B,de Waart DR,Maas A,Verheij J,Jansen PL,Damink SWO,Schaap FG,van Gulik TM,Heger M

更新日期：2018-11-08 00:00:00

abstract：:We propose a simple quantum voting scenario with a set of pairs of particles in a multi-particle entangled state. This scenario is suitable for large scale general votings. We also provide a proof of security of our scheme against the most general type of attack by generalizing Shor and Preskill's proof of security of...

journal_title：Scientific reports

authors： Xue P,Zhang X

更新日期：2017-08-08 00:00:00

abstract：:Anticarsia gemmatalis (velvetbean caterpillar) and Chrysodeixis includens (soybean looper) are two important defoliation pests of soybeans. In the present study, we have investigated the susceptibility and brush border membrane-binding properties of both species to Bacillus thuringiensis Cry1Ea toxin. Bioassays perfor...

journal_title：Scientific reports

authors： Bel Y,Zack M,Narva K,Escriche B

更新日期：2019-12-03 00:00:00

abstract：:G-proteins are implicated in plant productivity, but their genome-wide roles in regulating agronomically important traits remain uncharacterized. Transcriptomic analyses of rice G-protein alpha subunit mutant (rga1) revealed 2270 differentially expressed genes (DEGs) including those involved in C/N and lipid metabolis...

journal_title：Scientific reports

authors： Pathak RR,Mandal VK,Jangam AP,Sharma N,Madan B,Jaiswal DK,Raghuram N

更新日期：2021-01-27 00:00:00

abstract：:The impacts of ecosystem engineers may be expected to vary along environmental gradients. Due to some resources being more limited in arid than in mesic environments, disturbances created by burrowing mammals are expected to have a greater ameliorating effect in arid environments, with larger differences in microhabit...

journal_title：Scientific reports

authors： Louw MA,Haussmann NS,le Roux PC

更新日期：2019-12-18 00:00:00

abstract：:In the present work, an attempt has been made to synthesize the 1,2,3-triazole derivatives resulting from the click reaction, in a mild and green environment using the new copper(II)-coated magnetic core-shell nanoparticles Fe3O4@SiO2 modified by isatoic anhydride. The structure of the catalyst has been determined by ...

journal_title：Scientific reports

authors： Rajabi-Moghaddam H,Naimi-Jamal MR,Tajbakhsh M

更新日期：2021-01-22 00:00:00