Manipulation of visible-light polarization with dendritic cell-cluster metasurfaces.

abstract：:The recent breakthrough in the discovery of Weyl fermions in monopnictide semimetals provides opportunities to explore the exotic properties of relativistic fermions in condensed matter. The chiral anomaly-induced negative magnetoresistance and π Berry phase are two fundamental transport properties associated with the...

journal_title：Scientific reports

authors： Hu J,Liu JY,Graf D,Radmanesh SM,Adams DJ,Chuang A,Wang Y,Chiorescu I,Wei J,Spinu L,Mao ZQ

更新日期：2016-01-04 00:00:00

abstract：:Transport of tissue-derived lymphatic fluid and clearance by draining lymph nodes are pivotal for maintenance of fluid homeostasis in the body and for immune-surveillance of the self- and non-self-proteomes. Yet a quantitative analysis of nodal filtration of the tissue-derived proteome present in lymphatic fluid has n...

journal_title：Scientific reports

authors： Clement CC,Wang W,Dzieciatkowska M,Cortese M,Hansen KC,Becerra A,Thangaswamy S,Nizamutdinova I,Moon JY,Stern LJ,Gashev AA,Zawieja D,Santambrogio L

更新日期：2018-07-26 00:00:00

abstract：:Jasmonates (JAs) are plant-specific key signaling molecules that respond to various stimuli and are involved in the synthesis of secondary metabolites. However, little is known about the JA signal pathway, especially in economically significant medicinal plants. To determine the functions of novel genes that participa...

journal_title：Scientific reports

authors： Ge Q,Zhang Y,Hua WP,Wu YC,Jin XX,Song SH,Wang ZZ

更新日期：2015-09-21 00:00:00

abstract：:Memristive systems have gained considerable attention in the field of neuromorphic engineering, because they allow the emulation of synaptic functionality in solid state nano-physical systems. In this study, we show that memristive behavior provides a broad working framework for the phenomenological modelling of cellu...

journal_title：Scientific reports

authors： Diederich N,Bartsch T,Kohlstedt H,Ziegler M

更新日期：2018-06-19 00:00:00

abstract：:The aperture stop of the iris is subject to refraction by the cornea, and thus an outside observer sees a virtual image: the "entrance pupil" of the eye. When viewed off-axis, the entrance pupil has an elliptical form. The precise appearance of the entrance pupil is a consequence of the anatomical and optical properti...

journal_title：Scientific reports

authors： Aguirre GK

更新日期：2019-06-27 00:00:00

abstract：:MicroRNAs are arising as the next generation of diagnostic and therapeutic tools for gene silencing. Studies demonstrated that the miR-29 expression is decreased in Alzheimer's disease (AD) patients displaying high levels of human β-secretase (hBACE1). Recent advances toward an effective therapy for AD intend to emplo...

journal_title：Scientific reports

authors： Pereira PA,Tomás JF,Queiroz JA,Figueiras AR,Sousa F

更新日期：2016-01-28 00:00:00

abstract：:The emergence of metallic conduction in layered dichalcogenide semiconductor materials by chemical doping is one of key issues for two-dimensional (2D) materials engineering. At present, doping methods for layered dichalcogenide materials have been limited to an ion intercalation between layer units or electrostatic c...

journal_title：Scientific reports

authors： Kim SI,Hwang S,Kim SY,Lee WJ,Jung DW,Moon KS,Park HJ,Cho YJ,Cho YH,Kim JH,Yun DJ,Lee KH,Han IT,Lee K,Sohn Y

更新日期：2016-01-21 00:00:00

abstract：:The striatum plays important motor, associative and cognitive roles in brain functions. However, the rodent dorsolateral (the primate putamen) and dorsomedial (the primate caudate nucleus) striatum are not anatomically separated, making it difficult to distinguish their functions. By contrast, anatomical separation ex...

journal_title：Scientific reports

authors： Takaji M,Takemoto A,Yokoyama C,Watakabe A,Mizukami H,Ozawa K,Onoe H,Nakamura K,Yamamori T

更新日期：2016-11-02 00:00:00

abstract：:GPR88 is an orphan G-protein-coupled receptor with predominant expression in reward-related areas in the brain. While the lack of GPR88 has been demonstrated to induce behavioral deficits, the potential function of the receptor in the control of food intake and energy balance remains unexplored. In this work, the role...

journal_title：Scientific reports

authors： Lau J,Farzi A,Enriquez RF,Shi YC,Herzog H

更新日期：2017-08-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Cazanave S,Podtelezhnikov A,Jensen K,Seneshaw M,Kumar DP,Min HK,Santhekadur PK,Banini B,Mauro AG,Oseini AM,Vincent R,Tanis KQ,Webber AL,Wang L,Bedossa P,Mirshahi F,Sanyal AJ

更新日期：2020-05-15 00:00:00

abstract：:A pancreatic β-cell line MIN6 was previously established in our lab from an insulinoma developed in an IT6 transgenic mouse expressing the SV40 T antigen in β-cells. This cell line has been widely used for in vitro analysis of β-cell function, but tends to lose the mature β-cell features, including glucose-stimulated ...

journal_title：Scientific reports

authors： Miyazaki S,Tashiro F,Tsuchiya T,Sasaki K,Miyazaki JI

更新日期：2021-01-12 00:00:00

abstract：:Resistance of cancer cells to radiotherapy is a major clinical problem in cancer treatment. Therefore, understanding the molecular basis of cellular resistance to radiotherapy and identification of novel targets are essential for improving treatment efficacy for cancer patients. Our previous studies have demonstrated ...

journal_title：Scientific reports

authors： Chen S,Zhang Y,Zhang D

更新日期：2015-09-30 00:00:00

abstract：:We investigated body mass index (BMI) trajectories in the first 2 years of life in 1170 children from an Asian mother-offspring cohort in Singapore, and examined their predictors and associations with childhood cardio-metabolic risk measures at 5 years. Latent class growth mixture modelling analyses were performed to ...

journal_title：Scientific reports

authors： Aris IM,Chen LW,Tint MT,Pang WW,Soh SE,Saw SM,Shek LP,Tan KH,Gluckman PD,Chong YS,Yap F,Godfrey KM,Kramer MS,Lee YS

更新日期：2017-08-21 00:00:00

abstract：:Haemoparasites are responsible for some of the most prevalent and debilitating canine illnesses across the globe, whilst also posing a significant zoonotic risk to humankind. Nowhere are the effects of such parasites more pronounced than in developing countries in the tropics where the abundance and diversity of ectop...

journal_title：Scientific reports

authors： Huggins LG,Koehler AV,Ng-Nguyen D,Wilcox S,Schunack B,Inpankaew T,Traub RJ

更新日期：2019-09-02 00:00:00

abstract：:Small molecule based targeted therapies for the treatment of metastatic melanoma hold promise but responses are often not durable, and tumors frequently relapse. Response to adoptive cell transfer (ACT)-based immunotherapy in melanoma patients are durable but patients develop resistance primarily due to loss of antige...

journal_title：Scientific reports

authors： Dextras C,Dashnyam M,Griner LAM,Sundaresan J,Chim B,Yu Z,Vodnala S,Lee CR,Hu X,Southall N,Marugan JJ,Jadhav A,Restifo NP,Acquavella N,Ferrer M,Singh A

更新日期：2020-03-30 00:00:00

abstract：:G protein-coupled receptors (GPCRs), including dopamine receptors, represent a group of important pharmacological targets. An increased formation of dopamine receptor D2 homodimers has been suggested to be associated with the pathophysiology of schizophrenia. Selective labeling and ligand-induced modulation of dimeriz...

journal_title：Scientific reports

authors： Tabor A,Weisenburger S,Banerjee A,Purkayastha N,Kaindl JM,Hübner H,Wei L,Grömer TW,Kornhuber J,Tschammer N,Birdsall NJ,Mashanov GI,Sandoghdar V,Gmeiner P

更新日期：2016-09-12 00:00:00

abstract：:Electromagnetic resonances in conducting structures give rise to the enhancement of local fields and extinction efficiencies. Conducting structures are conventionally fabricated with a fixed geometry that determines their resonant response. Here, we challenge this conventional approach by demonstrating the photo-gener...

journal_title：Scientific reports

authors： Georgiou G,Tyagi HK,Mulder P,Bauhuis GJ,Schermer JJ,Rivas JG

更新日期：2014-01-07 00:00:00

abstract：:The influenza A virus RNA polymerase cleaves the 5' end of host pre-mRNAs and uses the capped RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5' ends of viral mRNAs from all genome segments transcribed in both human (A549) and mouse (M-1) cells infected with the influenza A/HongK...

journal_title：Scientific reports

authors： Sikora D,Rocheleau L,Brown EG,Pelchat M

更新日期：2014-08-26 00:00:00

abstract：:Unimolecular dual agonists for the glucagon-like peptide 1 receptor (GLP1R) and glucagon receptor (GCGR) are emerging as a potential new class of important therapeutics in type 2 diabetes (T2D). Reliable and quantitative assessments of in vivo occupancy on each receptor would improve the understanding of the efficacy ...

journal_title：Scientific reports

authors： Eriksson O,Haack T,Hijazi Y,Teichert L,Tavernier V,Laitinen I,Berglund JE,Antoni G,Velikyan I,Johansson L,Pierrou S,Wagner M,Tillner J

更新日期：2020-10-07 00:00:00

abstract：:Short-term exposures to outdoor air pollutants have been associated with lower lung function, but the results are inconsistence. The effects of different pollutant levels on lung function changes are still unclear. We quantified the effects of outdoor air pollution exposure (NO2, PM10, O3, and PM2.5) on lung function ...

journal_title：Scientific reports

authors： Zhou Y,Liu Y,Song Y,Xie J,Cui X,Zhang B,Shi T,Yuan J,Chen W

更新日期：2016-10-13 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome...

journal_title：Scientific reports

authors： Ren H,Li F,Tian C,Nie H,Wang L,Li HH,Zheng Y

更新日期：2015-10-28 00:00:00

abstract：:We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10tm2) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozygous mutants. In vitro, we confirmed that Hdl-Myo10 does not induce fi...

journal_title：Scientific reports

authors： Bachg AC,Horsthemke M,Skryabin BV,Klasen T,Nagelmann N,Faber C,Woodham E,Machesky LM,Bachg S,Stange R,Jeong HW,Adams RH,Bähler M,Hanley PJ

更新日期：2019-01-24 00:00:00

abstract：:Lipidomic analyses address the problem of characterizing the lipid components of given cells, tissues and organisms by means of chromatographic separations coupled to high-resolution, tandem mass spectrometry analyses. A number of software tools have been developed to help in the daunting task of mass spectrometry sig...

journal_title：Scientific reports

authors： Manzini S,Busnelli M,Colombo A,Kiamehr M,Chiesa G

更新日期：2020-08-07 00:00:00

abstract：:Low miR-96-5p expression is characteristic of many cancers but its role in breast cancer (BCa) remains poorly defined. Here, the role of miR-96-5p in BC development was assessed. We demonstrate that exogenously expressing miR-96-5p inhibits the proliferative, migratory and invasive capacity of BCa cells. Mechanistical...

journal_title：Scientific reports

authors： Gao XH,Zhang YL,Zhang ZY,Guo SS,Chen XB,Guo YZ

更新日期：2020-01-08 00:00:00

abstract：:Hypoxia inducible factor-1α (HIF-1α) pathway is associated with many vascular diseases, including atherosclerosis, arterial aneurysms, pulmonary hypertension and chronic venous diseases. Significant HIF-1α expression could be found at the rupture edge at human abdominal aortic aneurysm (AAA) tissues. While our initial...

journal_title：Scientific reports

authors： Tsai SH,Huang PH,Hsu YJ,Peng YJ,Lee CH,Wang JC,Chen JW,Lin SJ

更新日期：2016-07-01 00:00:00

abstract：:The early Pliocene shoaling of the Central American Seaway (CAS), ~4.7-4.2 million years ago (mega annum-Ma), is thought to have strengthened Atlantic Meridional Overturning Circulation (AMOC). The associated increase in northward flux of heat and moisture may have significantly influenced the evolution of Pliocene cl...

journal_title：Scientific reports

authors： Bell DB,Jung SJ,Kroon D,Hodell DA,Lourens LJ,Raymo ME

更新日期：2015-07-20 00:00:00

abstract：:Transcriptional enhancers are non-coding segments of DNA that play a central role in the spatiotemporal regulation of gene expression programs. However, systematically and precisely predicting enhancers remain a major challenge. Although existing methods have achieved some success in enhancer prediction, they still su...

journal_title：Scientific reports

authors： Liu F,Li H,Ren C,Bo X,Shu W

更新日期：2016-06-22 00:00:00

abstract：:HSV-2 is one of the most common sexually transmitted pathogens worldwide and HSV-2 infection triggers cytokine and chemokine production. However, little is known about which HSV-2 genes engage in the regulation of NF-κB signaling and what mechanisms are involved. In a screen of the unique short (Us) regions of HSV-2, ...

journal_title：Scientific reports

authors： Lu X,Huang C,Zhang Y,Lin Y,Wang X,Li Q,Liu S,Tang J,Zhou L

更新日期：2017-08-21 00:00:00

abstract：:BK virus (BKV) associated nephropathy (BKVAN) is still an important cause of allograft dysfunction after kidney transplantation (KT). Recent data have shown that the new interferon (IFN)-λ family has been ascribed antiviral properties similar to IFNα, and that the response to IFNλ in kidney is restricted to epithelial...

journal_title：Scientific reports

authors： Dvir R,Paloschi V,Canducci F,Dell'Antonio G,Racca S,Caldara R,Pantaleo G,Clementi M,Secchi A

更新日期：2017-07-27 00:00:00

abstract：:Genome editing has emerged as a technology with a potential to revolutionize plant breeding. In this study, we report on generating, in less than ten months, Tomelo, a non-transgenic tomato variety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology. We used whole-genome sequencing to show...

journal_title：Scientific reports

authors： Nekrasov V,Wang C,Win J,Lanz C,Weigel D,Kamoun S

更新日期：2017-03-28 00:00:00