LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

abstract：:Perovskite solar cells based on series of inorganic cesium lead bromide and iodide mixture, CsPbBr3-xI x , where x varies between 0, 0.1, 0.2, and 0.3 molar ratio were synthesized by two step-sequential deposition at ambient condition to design the variations of wide band gap light absorbers. A device with high overal...

journal_title：Scientific reports

authors： Ng CH,Ripolles TS,Hamada K,Teo SH,Lim HN,Bisquert J,Hayase S

更新日期：2018-02-06 00:00:00

abstract：:The relationship among the single nucleotide polymorphisms (SNPs) of the C-X-C motif chemokine ligand 12 gene (CXCL12) and the serum lipid profiles in the Chinese population has rarely been described, especially in somewhat old-fashioned and isolated Maonan minority. The goal of the current study was to elucidate the ...

journal_title：Scientific reports

authors： Qiu L,Yin RX,Nie RJ,Hu XJ,Khounphinith E,Zhang FH

更新日期：2019-12-20 00:00:00

abstract：:Repeated cycles of post-remission high-dose cytarabine (Ara-C) have been suggested to improve survival in core binding factor (CBF) acute myeloid leukaemia (AML). High-dose Ara-C used for induction regimens has also been reported to be associated with increased treatment-related mortality (TRM). Few data are available...

journal_title：Scientific reports

authors： Wang B,Zhang J,Hua X,Li H,Wang Z,Yang B

更新日期：2020-01-20 00:00:00

abstract：:An enormous amount of tumor sequencing data has been generated through large scale sequencing efforts. The functional consequences of the majority of mutations identified by such projects remain an open, unexplored question. This problem is particularly complicated in the case of rare mutations where frequency of occu...

journal_title：Scientific reports

authors： Katigbak A,Cencic R,Robert F,Sénécha P,Scuoppo C,Pelletier J

更新日期：2016-12-16 00:00:00

abstract：:This study aimed to explore the effects of radiochemotherapy on the neurocognitive function of patients with high-grade gliomas (HGG). The mini-mental state examination (MMSE), Montreal Cognitive Assessment (MoCA), event-related potential P300 (ERP-P300), and specific MRI parameters were compared, and the associations...

journal_title：Scientific reports

authors： Bian Y,Meng L,Peng J,Li J,Wei R,Huo L,Yang H,Wang Y,Fu J,Shen L,Hong J

更新日期：2019-04-12 00:00:00

abstract：:Fibrolamellar carcinoma (FLC) is a unique liver cancer primarily affecting young adults and characterized by a fusion event between DNAJB1 and PRKACA. By analyzing RNA-sequencing data from The Cancer Genome Atlas (TCGA) for >9,100 tumors across ~30 cancer types, we show that the DNAJB1-PRKACA fusion is specific to FLC...

journal_title：Scientific reports

authors： Dinh TA,Vitucci EC,Wauthier E,Graham RP,Pitman WA,Oikawa T,Chen M,Silva GO,Greene KG,Torbenson MS,Reid LM,Sethupathy P

更新日期：2017-03-17 00:00:00

abstract：:We introduce multi-gradients including Laplace pressure gradient, wettable gradient and wettable different gradient on a high adhesion surface via special wedge-pattern and improved anodic oxidation method. As a result of the cooperative effect mentioned above, controlled directional motion of a droplet on a high adhe...

journal_title：Scientific reports

authors： Deng S,Shang W,Feng S,Zhu S,Xing Y,Li D,Hou Y,Zheng Y

更新日期：2017-04-03 00:00:00

abstract：:The ferritic Fe-Cr-Ni-Al-Ti alloys strengthened by hierarchical-Ni2TiAl/NiAl or single-Ni2TiAl precipitates have been developed and received great attentions due to their superior creep resistance, as compared to conventional ferritic steels. Although the significant improvement of the creep resistance is achieved in ...

journal_title：Scientific reports

authors： Song G,Sun Z,Li L,Clausen B,Zhang SY,Gao Y,Liaw PK

更新日期：2017-04-07 00:00:00

abstract：:The lignite biodegradation procedure to produce water-soluble humic materials (WSHM) with a Penicillium stain was established by previous studies in our laboratory. This study researched the effects of WSHM on the growth of Bradyrhizobium liaoningense CCBAU05525 and its nodulation on soybean. Results showed that WSHM ...

journal_title：Scientific reports

authors： Guo Gao T,Yuan Xu Y,Jiang F,Zhen Li B,Shui Yang J,Tao Wang E,Li Yuan H

更新日期：2015-06-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Sanjeev A,Kapellner Y,Shabairou N,Gur E,Sinvani M,Zalevsky Z

更新日期：2020-04-02 00:00:00

abstract：:Cisplatin is one of the most widely used chemotherapeutic agents in the treatment of different tumors but has high toxicity and side effects. Therefore, the synthesis of new chemotherapeutic agents is necessary, so that they are effective in the treatment of cancer while avoiding such toxicity. In this study, we have ...

journal_title：Scientific reports

authors： Espino J,Fernández-Delgado E,Estirado S,de la Cruz-Martinez F,Villa-Carballar S,Viñuelas-Zahínos E,Luna-Giles F,Pariente JA

更新日期：2020-10-07 00:00:00

abstract：:Sirtuin 1 (SIRT1) is involved in both aging and circadian-clock regulation, yet the link between the two processes in relation to SIRT1 function is not clear. Using Sirt1-deficient mice, we found that Sirt1 and Period 2 (Per2) constitute a reciprocal negative regulation loop that plays important roles in modulating he...

journal_title：Scientific reports

authors： Wang RH,Zhao T,Cui K,Hu G,Chen Q,Chen W,Wang XW,Soto-Gutierrez A,Zhao K,Deng CX

更新日期：2016-06-27 00:00:00

abstract：:We propose a model of a learning agent whose interaction with the environment is governed by a simulation-based projection, which allows the agent to project itself into future situations before it takes real action. Projective simulation is based on a random walk through a network of clips, which are elementary patch...

journal_title：Scientific reports

authors： Briegel HJ,De las Cuevas G

更新日期：2012-01-01 00:00:00

abstract：:We investigated the cognitive and behavioral profile of three distinct groups of epilepsies with a genetic background for intergroup differences: (1) idiopathic/genetic generalized epilepsies (IGE/GGE group); (2) idiopathic focal epilepsies (IFE group); and (3) epilepsies with proven or strongly suggested monogenic or...

journal_title：Scientific reports

authors： Moorhouse FJ,Cornell S,Gerstl L,Tacke M,Roser T,Heinen F,Bonfert M,von Stülpnagel C,Wagner M,Borggraefe I

更新日期：2020-12-09 00:00:00

abstract：:Cancer dissemination is initiated by the movement of cells into the vasculature which has been reported to be triggered by EMT (epithelial to mesenchymal transition). Cellular dissemination also requires proteases that remodel the extracellular matrix. The protease, plasmin is a prominent player in matrix remodeling a...

journal_title：Scientific reports

authors： Bydoun M,Sterea A,Weaver ICG,Bharadwaj AG,Waisman DM

更新日期：2018-09-20 00:00:00

abstract：:Non-compressible hemorrhage is the most common preventable cause of death on battlefield and in civilian traumatic injuries. We report the use of microsecond pulses of electric current to induce rapid constriction in femoral and mesenteric arteries and veins in rats. Electrically-induced vasoconstriction could be indu...

journal_title：Scientific reports

authors： Mandel Y,Manivanh R,Dalal R,Huie P,Wang J,Brinton M,Palanker D

更新日期：2013-01-01 00:00:00

abstract：:Pupillary light reflex (PLR) is an involuntary response where the pupil size changes with luminance. Studies have shown that PLR response was altered in children with autism spectrum disorders (ASDs) and other neurological disorders. However, PLR in infants and toddlers is still understudied. We conducted a longitudin...

journal_title：Scientific reports

authors： Kercher C,Azinfar L,Dinalankara DMR,Takahashi TN,Miles JH,Yao G

更新日期：2020-01-27 00:00:00

abstract：:Small for gestational age (SGA) newborns are often born from hypertensive pregnancies. This study aimed to compare the systemic metabolism of cortisol (F) in pregnancies with SGA and appropriate for gestational age (AGA) infants, considering both the normotensive (NT) and hypertensive patients. We hypothesized that th...

journal_title：Scientific reports

authors： Siemiątkowska A,Kosicka K,Szpera-Goździewicz A,Krzyścin M,Bręborowicz GH,Główka FK

更新日期：2019-11-29 00:00:00

abstract：:Willow (Salix spp.) seeds are able to tolerate desiccation, but differ from typical orthodox seeds in that they lose viability in a few days at room temperature, and in that the chloroplasts in embryo tissues do not dedifferentiate during maturation drying, thus retaining chlorophyll and maintaining intact their thyla...

journal_title：Scientific reports

authors： López-Fernández MP,Moyano L,Correa MD,Vasile F,Burrieza HP,Maldonado S

更新日期：2018-11-21 00:00:00

abstract：:Acoustic energy transfer is a promising energy harvesting technology candidate for implantable biomedical devices. However, it does not show competitive strength for enabling self-powered implantable biomedical devices due to two issues - large size of bulk piezoelectric ultrasound transducers and output power fluctua...

journal_title：Scientific reports

authors： Shi Q,Wang T,Lee C

更新日期：2016-04-26 00:00:00

abstract：:The nutritional alarmones ppGpp and pppGpp (collectively: (p)ppGpp) are nucleotide-based second messengers enabling bacteria to respond to environmental and stress conditions. Several bacterial species contain two highly homologous (p)ppGpp synthetases named RelP (SAS2, YwaC) and RelQ (SAS1, YjbM). It is established t...

journal_title：Scientific reports

authors： Steinchen W,Vogt MS,Altegoer F,Giammarinaro PI,Horvatek P,Wolz C,Bange G

更新日期：2018-02-01 00:00:00

abstract：:Arthroplasty is a surgical procedure to restore the function of the joint of patient suffering from knee osteoarthritis. However, postoperative functional deficits are reported even after a rehabilitation program. In order to determine the origin of functional deficits of patient suffering from knee osteoarthritis and...

journal_title：Scientific reports

authors： Lecocq M,Linares JM,Chaves-Jacob J,Coyle T,Roffino S,Eyraud M,Gigmes D,Decherchi P,Dousset E

更新日期：2020-03-24 00:00:00

abstract：:Aggression and responsiveness to noxious stimuli are adaptable traits that are ubiquitous throughout the animal kingdom. Like vertebrate animals, some invertebrates have been shown to exhibit anxiety-like behaviour and altered levels of aggression that are modulated by the neurotransmitter serotonin. To investigate wh...

journal_title：Scientific reports

authors： Hamilton TJ,Kwan GT,Gallup J,Tresguerres M

更新日期：2016-01-25 00:00:00

abstract：:Insecticides are the main method of controlling lepidopteran pests of eucalyptus plantations and those selective to natural enemies, such as the endoparasitoid Palmistichus elaeisis Delvare et LaSalle (Hymenoptera: Eulophidae), are preferable. The objective of this study was to evaluate the selectivity and effects on ...

journal_title：Scientific reports

authors： Pereira Costa ES,Soares MA,Caldeira ZV,Von Dos Santos Veloso R,da Silva LA,da Silva DJH,de Lima Santos IC,de Castro E Castro BM,Zanuncio JC,Legaspi JC

更新日期：2020-07-24 00:00:00

abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

journal_title：Scientific reports

authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

更新日期：2017-09-19 00:00:00

abstract：:The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the present study, prim...

journal_title：Scientific reports

authors： Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C

更新日期：2016-07-08 00:00:00

abstract：:Methanol (MOH) and monomethylamine (MMA) are two typical one-carbon (C1) compounds found in natural environments. They play an important role in marine and atmospheric chemistry, cloud formation, and global climate. The main biological sink of MOH and MMA is rapid consumption by marine microbes. Here, field-based time...

journal_title：Scientific reports

authors： Deng W,Peng L,Jiao N,Zhang Y

更新日期：2018-10-18 00:00:00

abstract：:In many vertebrates, acoustic cues to body size are encoded in resonance frequencies of the vocal tract ("formants"), rather than in the rate of tissue vibration in the sound source ("pitch"). Anatomical constraints on the vocal tract's size render formants honest cues to size in many bird and mammal species, but it i...

journal_title：Scientific reports

authors： Reber SA,Janisch J,Torregrosa K,Darlington J,Vliet KA,Fitch WT

更新日期：2017-05-12 00:00:00

abstract：:Diabetes is a chronic metabolic disease that causes blood glucose (BG) concentration to make dangerous excursions outside its physiological range. Measuring the fraction of time spent by BG outside this range, and, specifically, the time-below-range (TBR), is a clinically common way to quantify the effectiveness of th...

journal_title：Scientific reports

authors： Camerlingo N,Vettoretti M,Facchinetti A,Sparacino G,Mader JK,Choudhary P,Del Favero S

更新日期：2020-10-23 00:00:00

abstract：:The investigation of chemical and structural dynamics in battery materials is essential to elucidation of structure-property relationships for rational design of advanced battery materials. Spatially resolved techniques, such as scanning/transmission electron microscopy (S/TEM), are widely applied to address this chal...

journal_title：Scientific reports

authors： Lin F,Markus IM,Doeff MM,Xin HL

更新日期：2014-07-16 00:00:00