Synthesis and structure of a new thiazoline-based palladium(II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cells.

abstract：:Measurement techniques that allow the global analysis of cellular responses while retaining single-cell sensitivity are increasingly needed in order to understand complex and dynamic biological processes. In this context, compromises between sensitivity, degree of multiplexing, throughput, and invasiveness are often u...

journal_title：Scientific reports

authors： Pavillon N,Smith NI

更新日期：2019-11-19 00:00:00

abstract：:The regulatory (neuro)peptide galanin and its three receptors (GAL1-3R) are involved in immunity and inflammation. Galanin alleviated inflammatory bowel disease (IBD) in rats. However, studies on the galanin receptors involved are lacking. We aimed to determine galanin receptor expression in IBD patients and to evalua...

journal_title：Scientific reports

authors： Brunner SM,Reichmann F,Leitner J,Wölfl S,Bereswill S,Farzi A,Schneider AM,Klieser E,Neureiter D,Emberger M,Heimesaat MM,Weghuber D,Lang R,Holzer P,Kofler B

更新日期：2021-01-12 00:00:00

abstract：:The proteolytic system of Lactobacillus plays an essential role in bacterial growth, contributes to the flavor development of fermented products, and can release bioactive health-beneficial peptides during milk fermentation. In this work, a genomic analysis of all genes involved in the proteolytic system of L. delbrue...

journal_title：Scientific reports

authors： Brown L,Villegas JM,Elean M,Fadda S,Mozzi F,Saavedra L,Hebert EM

更新日期：2017-08-17 00:00:00

abstract：:Transport of self-propelled particles in a two-dimensional (2D) separate channel is investigated in the presence of the combined forces. By applying an ac force, the particles will be trapped by the separate walls. A dc force produces the asymmetry of the system and induces the longitudinal directed transport. Due to ...

journal_title：Scientific reports

authors： Wu JC,Ai BQ

更新日期：2016-04-01 00:00:00

abstract：:Chemotaxonomy and the comparative analysis of metabolic features of fungi have the potential to provide valuable information relating to ecology and evolution, but have not been fully explored in fungal biology. Here, we investigated the chemical diversity of legume-associated Ascochyta and Phoma species and the possi...

journal_title：Scientific reports

authors： Kim W,Peever TL,Park JJ,Park CM,Gang DR,Xian M,Davidson JA,Infantino A,Kaiser WJ,Chen W

更新日期：2016-02-05 00:00:00

abstract：:Extreme weather events (e.g., cyclones, floods, droughts) are capable of changing ecosystems and altering how animals obtain resources. Understanding the behavioural responses of animals being impacted by these natural events can help initiate and ameliorate conservation or management programs. This study investigated...

journal_title：Scientific reports

authors： Matley JK,Eanes S,Nemeth RS,Jobsis PD

更新日期：2019-10-03 00:00:00

abstract：:L-Ascorbic acid (vitamin C, AA) exhibits anti-cancer effects with high-dose treatment through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. The anti-cancer effects of L-ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a transporter of L-ascorbic...

journal_title：Scientific reports

authors： Cho S,Chae JS,Shin H,Shin Y,Song H,Kim Y,Yoo BC,Roh K,Cho S,Kil EJ,Byun HS,Cho SH,Park S,Lee S,Yeom CH

更新日期：2018-07-27 00:00:00

abstract：:After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge. Therefore, there is a need to evaluate new imaging modalities, such as CT perfusion (CTP) to improve the visualization of coagulation necrosis. MWA and CTP...

journal_title：Scientific reports

authors： Bressem KK,Vahldiek JL,Erxleben C,Shnayien S,Poch F,Geyer B,Lehmann KS,Hamm B,Niehues SM

更新日期：2019-12-06 00:00:00

abstract：:Intraperitoneal administration of antibiotics together with peritoneal dialysis fluids (PDFs) remains the preferable route for treatment of peritoneal dialysis-related peritonitis. For home based therapy, antibiotic-containing PDFs are stored for up to two weeks and warmed up to body-temperature before administration....

journal_title：Scientific reports

authors： Kussmann M,Ferth A,Obermüller M,Pichler P,Zeitlinger M,Wiesholzer M,Burgmann H,Poeppl W,Reznicek G

更新日期：2019-04-24 00:00:00

abstract：:Chrysopidae (green lacewings) is the second largest family in Neuroptera, and it includes medium-size lacewings largely recognized by the presence of golden-colored eyes, bright green bodies and delicate wings with dense venation patterns. The subfamily Chrysopinae includes 97% of the species diversity in the family a...

journal_title：Scientific reports

authors： Jiang Y,Garzón-Orduña IJ,Winterton SL,Yang F,Liu X

更新日期：2017-08-03 00:00:00

abstract：:Ecdysteroids (arthropod molting hormones) play an important role in the development and sexual maturation of arthropods, and they have been shown to have anabolic and "energizing" effect in higher vertebrates. The aim of this study was to assess ecdysteroid diversity, levels according to bird species and months, as we...

journal_title：Scientific reports

authors： Hornok S,Csorba A,Kováts D,Csörgő T,Hunyadi A

更新日期：2019-11-18 00:00:00

abstract：:Protein aggregation is a common biological phenomenon, observed in different physiological and pathological conditions. Decreased protein solubility and a tendency to aggregate is also observed during physiological aging but the causes are currently unknown. Herein we performed a biophysical separation of aging-relate...

journal_title：Scientific reports

authors： Tanase M,Urbanska AM,Zolla V,Clement CC,Huang L,Morozova K,Follo C,Goldberg M,Roda B,Reschiglian P,Santambrogio L

更新日期：2016-01-18 00:00:00

abstract：:Understanding of avian nocturnal flight comes mainly from northern hemisphere species in seasonal temperate ecosystems where nocturnal flight is often precisely timed and entrained by annual photoperiod. Here we investigate patterns of nocturnal flight in waterbirds of Australian desert ecosystems that fly considerabl...

journal_title：Scientific reports

authors： McEvoy JF,Ribot RFH,Wingfield JC,Bennett ATD

更新日期：2017-12-14 00:00:00

abstract：:New ionic liquids with multiple Brönsted acid sites were synthesized in ≥98% yield, and their inhibiting properties for the corrosion of carbon steel in 0.5 M HCl solution had been evaluated using electrochemical impedance spectroscopy, potentiodynamic polarization and weight loss method, finally the possible inhibiti...

journal_title：Scientific reports

authors： Cao S,Liu D,Zhang P,Yang L,Yang P,Lu H,Gui J

更新日期：2017-08-18 00:00:00

abstract：:Cardiotrophin-1 is known to be a key regulator of energy homeostasis, as well as glucose and lipid metabolism in vivo. However, there are inconsistent results of the association between cardiotrophin-1 and obesity in humans, possibly confounded by hyperglycemia. Therefore, the aim of this study was to investigate the ...

journal_title：Scientific reports

authors： Hung HC,Lu FH,Wu HT,Ou HY,Yang YC,Wu JS,Chang CJ

更新日期：2015-12-01 00:00:00

abstract：:Two supramolecular complexes of trans-1⊂CB[8] and trans-2⊂CB[8] were successfully achieved by the controlled selective complexation process of cucurbit[8]uril (CB[8]) with hetero-guest pair containing azobenzene and bispyridinium moieties in aqueous solution, exhibiting the reversibly light-driven movements of CB[8] u...

journal_title：Scientific reports

authors： Cheng HB,Zhang YM,Xu C,Liu Y

更新日期：2014-02-27 00:00:00

abstract：:Editor's Note: this Article has been retracted; the Retraction Note is available at https://www.nature.com/articles/s41598-020-76500-9. ...

journal_title：Scientific reports

authors： Sudhakar YA,Verma RK,Pawar SC

更新日期：2020-11-26 00:00:00

abstract：:F-box and WD40 domain protein 7 (FBXW7) is a component of the SKP1-CUL1-F-box protein (SCF) complex that mediates the ubiquitination of diverse oncogenic target proteins. The exploration of FBXW7 mutations in human primary cancer has revealed three mutation hotspots at conserved arginine residues (Arg465, Arg479, and ...

journal_title：Scientific reports

authors： Ikenoue T,Terakado Y,Zhu C,Liu X,Ohsugi T,Matsubara D,Fujii T,Kakuta S,Kubo S,Shibata T,Yamaguchi K,Iwakura Y,Furukawa Y

更新日期：2018-01-31 00:00:00

abstract：:The increasing demand for healthy baked goods boosted studies on sourdough microbiota with beneficial metabolic traits, to be used as potential functional starters. Here, 139 yeasts isolated from cereal-based fermented foods were in vitro characterized for their phytase and antioxidant activities. The molecular charac...

journal_title：Scientific reports

authors： Palla M,Blandino M,Grassi A,Giordano D,Sgherri C,Quartacci MF,Reyneri A,Agnolucci M,Giovannetti M

更新日期：2020-07-30 00:00:00

abstract：:Increased p66Shc expression has been associated with diabetic nephropathy (DN). However, whether p66Shc can serve as a potential biomarker for tubular oxidative injury in DN is unknown. We measured the expression of p66Shc in peripheral blood monocytes (PBMs) and renal biopsy tissues from DN patients and then analysed...

journal_title：Scientific reports

authors： Xu X,Zhu X,Ma M,Han Y,Hu C,Yuan S,Yang Y,Xiao L,Liu F,Kanwar YS,Sun L

更新日期：2016-07-05 00:00:00

abstract：:Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale ranges from 20.4 to 30.5 mg kg-1, showing a solid gap to the biofortification target for human health (40 mg ...

journal_title：Scientific reports

authors： Chen XP,Zhang YQ,Tong YP,Xue YF,Liu DY,Zhang W,Deng Y,Meng QF,Yue SC,Yan P,Cui ZL,Shi XJ,Guo SW,Sun YX,Ye YL,Wang ZH,Jia LL,Ma WQ,He MR,Zhang XY,Kou CL,Li YT,Tan DS,Cakmak I,Zhang FS,Zou CQ

更新日期：2017-08-01 00:00:00

abstract：:Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the salvage pathway of nicotinamide adenine dinucleotide biosynthesis. NAMPT protein is a secreted plasma biomarker in inflammation and in cancer. The NAMPT enzymatic inhibitor, FK866, acts as an inducer of apoptosis and is a cancer therapeuti...

journal_title：Scientific reports

authors： Zhou T,Wang T,Garcia JG

更新日期：2014-08-22 00:00:00

abstract：:Nanotechnology can improve the performance of dental polymers. The objective of this study was to modify the surfaces of nanoparticles with silanes and proteins, characterize nanoparticles' agglomeration levels and interfaces between nanoparticles and the polymeric matrix. Undoped (n-TiO2), nitrogen-doped (N_TiO2) and...

journal_title：Scientific reports

authors： Esteban Florez FL,Trofimov AA,Ievlev A,Qian S,Rondinone AJ,Khajotia SS

更新日期：2020-06-17 00:00:00

abstract：:Complex interactions occur between tumor and host immune system at each site in the metastatic setting, the outcome of which can determine behavior ranging from dormancy to rapid growth. An additional layer of complexity arises from the understanding that cytotoxic T cells can traffic through the host circulatory syst...

journal_title：Scientific reports

authors： Walker R,Poleszczuk J,Pilon-Thomas S,Kim S,Anderson AARA,Czerniecki BJ,Harrison LB,Moros EG,Enderling H

更新日期：2018-06-21 00:00:00

abstract：:Private Set Intersection Cardinality (PSI-CA) and Private Set Union Cardinality (PSU-CA) are two cryptographic primitives whereby two or more parties are able to obtain the cardinalities of the intersection and the union of their respective private sets, and the privacy of their sets is preserved. In this paper, we pr...

journal_title：Scientific reports

authors： Zhang C,Long Y,Sun Z,Li Q,Huang Q

更新日期：2020-12-17 00:00:00

abstract：:Bi-phasic or diauxic growth is often observed when microbes are grown in a chemically defined medium containing two sugars (for example glucose and lactose). Typically, the two growth stages are separated by an often lengthy phase of arrested growth, the so-called lag-phase. Diauxic growth is usually interpreted as an...

journal_title：Scientific reports

authors： Chu D,Barnes DJ

更新日期：2016-04-29 00:00:00

abstract：:A disposable cyclic voltammetry (CV) tag is printed on a plastic film by integrating wireless power transmitter, polarized triangle wave generator, electrochemical cell and signage through a scalable gravure printing method. By proximity of 13.56 MHz RF reader, the printed CV tag generates 320 mHz of triangular sweep ...

journal_title：Scientific reports

authors： Jung Y,Park H,Park JA,Noh J,Choi Y,Jung M,Jung K,Pyo M,Chen K,Javey A,Cho G

更新日期：2015-01-29 00:00:00

abstract：:Early diagnosis of hepatocellular carcinoma (HCC) remains challenging to date. Characteristic metabolic deregulations of HCC may enable novel biomarkers discovery for early diagnosis. A capillary electrophoresis-time of flight mass spectrometry (CE-TOF/MS)-based metabolomics approach was performed to discover and vali...

journal_title：Scientific reports

authors： Zeng J,Huang X,Zhou L,Tan Y,Hu C,Wang X,Niu J,Wang H,Lin X,Yin P

更新日期：2015-11-03 00:00:00

abstract：:Pertuzumab is an antihuman HER2 antibody developed for HER2 positive breast cancer. Glycosylation profiles are always the important issue for antibody based therapy. Previous findings have suggested the impact of glycosylation profiles on the function of antibodies, like pharmacodynamics, antibody-dependent cellular c...

journal_title：Scientific reports

authors： Luo C,Chen S,Xu N,Wang C,Sai WB,Zhao W,Li YC,Hu XJ,Tian H,Gao XD,Yao WB

更新日期：2017-04-11 00:00:00

abstract：:The dynamics of networks of neuronal cultures has been recently shown to be strongly dependent on the network geometry and in particular on their dimensionality. However, this phenomenon has been so far mostly unexplored from the theoretical point of view. Here we reveal the rich interplay between network geometry and...

journal_title：Scientific reports

authors： Millán AP,Torres JJ,Bianconi G

更新日期：2018-07-02 00:00:00