The expression and function of miR-424 in infantile skin hemangioma and its mechanism.

abstract：:The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and prognostic value o...

journal_title：Scientific reports

authors： Xiong J,Tang X,Hu Z,Nie L,Wang Y,Zhao J

更新日期：2015-12-07 00:00:00

abstract：:In mature erythrocytes, glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH) yield NADPH, a crucial cofactor of the enzyme glutathione reductase (GR) converting glutathione disulfide (GSSG) into its reduced state (GSH). GSH is essential for detoxification processes in and survival of ...

journal_title：Scientific reports

authors： Ghashghaeinia M,Giustarini D,Koralkova P,Köberle M,Alzoubi K,Bissinger R,Hosseinzadeh Z,Dreischer P,Bernhardt I,Lang F,Toulany M,Wieder T,Mojzikova R,Rossi R,Mrowietz U

更新日期：2016-06-29 00:00:00

abstract：:Although genetically modified mice can be generated with high efficiency by using CRISPR/Cas9-mediated genome editing in mouse zygotes, only the loci with a protospacer-adjacent motif (PAM) sequence are targetable. The present study investigated the usability of engineered Streptococcus pyogenes Cas9 (SpCas9-NG) in mo...

journal_title：Scientific reports

authors： Fujii W,Ito H,Kanke T,Ikeda A,Sugiura K,Naito K

更新日期：2019-09-09 00:00:00

abstract：:We propose and experimentally demonstrate real-time locating and speed measurement of fibre fuse by analysing the Doppler shift of reflected light using optical frequency-domain reflectometry (OFDR). Our method can detect the start of a fibre fuse within 200 ms which is equivalent to a propagation distance of about 10...

journal_title：Scientific reports

authors： Jiang S,Ma L,Fan X,Wang B,He Z

更新日期：2016-05-05 00:00:00

abstract：:Patients with dengue virus (DENV) infection may also present acute viral encephalitis through an unknown mechanism. Here, we report that encephalitic DENV-infected mice exhibited progressive hunchback posture, limbic seizures, limbic weakness, paralysis, and lethality 7 days post-infection. These symptoms were accompa...

journal_title：Scientific reports

authors： Tsai TT,Chen CL,Lin YS,Chang CP,Tsai CC,Cheng YL,Huang CC,Ho CJ,Lee YC,Lin LT,Jhan MK,Lin CF

更新日期：2016-06-09 00:00:00

abstract：:Fibril formation implies the conversion of a protein's native secondary structure and is associated with several neurodegenerative diseases. A better understanding of fibrillation inhibition and fibril dissection requires nanoscale molecular characterization of amyloid structures involved. Tip-enhanced Raman scatterin...

journal_title：Scientific reports

authors： Deckert-Gaudig T,Deckert V

更新日期：2016-12-23 00:00:00

abstract：:Miscarriage affects ~20% of pregnancies and maternal infections account for ~15% of early miscarriages. Chlamydia trachomatis (Ct) has been associated with miscarriage but the underlying mechanisms are unknown. Successful implantation requires endometrial stromal cell (ESC) decidualisation. Maintenance of pregnancy re...

journal_title：Scientific reports

authors： Giakoumelou S,Wheelhouse N,Brown J,Wade J,Simitsidellis I,Gibson D,Saunders PTK,Horner P,Entrican G,Howie SEM,Horne AW

更新日期：2017-05-17 00:00:00

abstract：:Design and development of efficient processes for continuous manufacturing of solid dosage oral formulations is of crucial importance for pharmaceutical industry in order to implement the Quality-by-Design paradigm. Supercritical solvent-based manufacturing can be utilized in pharmaceutical processing owing to its inh...

journal_title：Scientific reports

authors： Pishnamazi M,Zabihi S,Jamshidian S,Borousan F,Hezave AZ,Marjani A,Shirazian S

更新日期：2021-01-13 00:00:00

abstract：:Mycoplasma mobile, a fish pathogen, exhibits its own specialized gliding motility on host cells based on ATP hydrolysis. The special protein machinery enabling this motility is composed of surface and internal protein complexes. Four proteins, MMOBs 1630, 1660, 1670, and 4860 constitute the internal complex, including...

journal_title：Scientific reports

authors： Tulum I,Kimura K,Miyata M

更新日期：2020-03-02 00:00:00

abstract：:Parental age is increasing rapidly in many countries. Analysis of this potentially important influence on offspring well-being is hampered by strong secular trends and socioeconomic patterning and by a shortage of follow-up data for adult offspring. We used Swedish national data on up to 3,653,938 offspring to conside...

journal_title：Scientific reports

authors： Carslake D,Tynelius P,van den Berg G,Davey Smith G,Rasmussen F

更新日期：2017-03-27 00:00:00

abstract：:Since their first appearance, organic-inorganic perovskite absorbers have been capturing the attention of the scientific community. While high efficiency devices highlight the importance of band level alignment, very little is known on the origin of the strong n-doping character observed in the perovskite. Here, by me...

journal_title：Scientific reports

authors： Caputo M,Cefarin N,Radivo A,Demitri N,Gigli L,Plaisier JR,Panighel M,Di Santo G,Moretti S,Giglia A,Polentarutti M,De Angelis F,Mosconi E,Umari P,Tormen M,Goldoni A

更新日期：2019-10-22 00:00:00

abstract：:Cell counts decrease with sediment depth. Typical explanations consider limiting factors such as water availability and chemistry, carbon source, nutrients, energy and temperature, and overlook the role of pore size. Our analyses consider sediment self-compaction, the evolution of pore size with depth, and the probabi...

journal_title：Scientific reports

authors： Park J,Santamarina JC

更新日期：2020-12-10 00:00:00

abstract：:Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, current TNF-α blockers...

journal_title：Scientific reports

authors： Cui X,Chang L,Li Y,Lv Q,Wang F,Lin Y,Li W,Meade JD,Walden JC,Liang P

更新日期：2018-05-09 00:00:00

abstract：:Mucositis is the limiting toxicity of radio(chemo)therapy of head and neck cancer. Diagnostics, prophylaxis and correction of this condition demand new accurate and objective approaches. Here we report on an in vivo longitudinal monitoring of the oral mucosa dynamics in 25 patients during the course of radiotherapy of...

journal_title：Scientific reports

authors： Maslennikova AV,Sirotkina MA,Moiseev AA,Finagina ES,Ksenofontov SY,Gelikonov GV,Matveev LA,Kiseleva EB,Zaitsev VY,Zagaynova EV,Feldchtein FI,Gladkova ND,Vitkin A

更新日期：2017-11-28 00:00:00

abstract：:Rice stripe virus-infected females of the small brown planthopper (SBPH, Laodelphax striatellus) usually lay fewer eggs with a longer hatch period, low hatchability, malformation and retarded or defective development compared with healthy females. To explore the molecular mechanism of those phenomena, we analyzed the ...

journal_title：Scientific reports

authors： Liu B,Qin F,Liu W,Wang X

更新日期：2016-06-09 00:00:00

abstract：:PARP inhibitors have shown remarkable efficacy in the clinical management of several BRCA-mutated tumors. This approach is based on the long-standing hypothesis that PARP inhibition will impair the repair of single stranded breaks, causing synthetic lethality in tumors with loss of high-fidelity double-strand break ho...

journal_title：Scientific reports

authors： Principe DR,Narbutis M,Koch R,Rana A

更新日期：2020-11-19 00:00:00

abstract：:This study aimed to investigate changes in types of dental arch form during adolescence and explore adolescent changes in size and form of dental arch. Hong Kong Chinese were recruited and digital dental arch models were obtained at ages 12, 15, and 18 years. Geometric morphometrics was used to investigate adolescent ...

journal_title：Scientific reports

authors： Wen YF,Wong HM,Pei T,McGrath C

更新日期：2019-12-06 00:00:00

abstract：:We extend an agent-based multiscale model of vascular tumour growth and angiogenesis to describe transarterial chemoembolisation (TACE) therapies. The model accounts for tumour and normal cells that are both nested in a vascular system that changes its structure according to tumour-related growth factors. Oxygen promo...

journal_title：Scientific reports

authors： Perfahl H,Jain HV,Joshi T,Horger M,Malek N,Bitzer M,Reuss M

更新日期：2020-06-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Lee TH,Lim HB,Nam KY,Kim K,Kim JY

更新日期：2020-03-11 00:00:00

abstract：:For the first time, soil core samples from the Jiuquan region have been analyzed for Pu isotopes for radioactive source identification and radiological assessment. The Jiuquan region is in downwind from the Lop Nor Chinese nuclear test (CNT) site. The high Pu inventories (13 to 546 Bq/m(2)) in most of the sampling loc...

journal_title：Scientific reports

authors： Bu W,Ni Y,Guo Q,Zheng J,Uchida S

更新日期：2015-07-17 00:00:00

abstract：:To improve the performance of solar photovoltaic devices one should mitigate three types of losses: optical, electrical and thermal. However, further reducing the optical and electrical losses in modern photovoltaic devices is becoming increasingly costly. Therefore, there is a rising interest in minimizing the therma...

journal_title：Scientific reports

authors： Vaillon R,Dupré O,Cal RB,Calaf M

更新日期：2018-09-03 00:00:00

abstract：:CoO nanocrystal/graphene nanosheets (GNS) composites, consisting of a triangular CoO nanocrystal of 2~20 nm on the surface of GNS, are synthesized by a mild synthetic method. First, cobalt acetate tetrahydrate is recrystallized in the alcohol solution at a low temperature. Then, graphene oxide mixed with cobalt-precur...

journal_title：Scientific reports

authors： Guan Q,Cheng J,Li X,Wang B,Huang L,Nie F,Ni W

更新日期：2015-05-11 00:00:00

abstract：:Improving surface sensitivities of nanostructure-based plasmonic sensors is an important issue to be addressed. Among the SPR measurements, the wavelength interrogation is commonly utilized. We proposed using blue-shifted surface plasmon mode and Fano resonance, caused by the coupling of a cavity mode (angle-independe...

journal_title：Scientific reports

authors： Lee KL,Chang CC,You ML,Pan MY,Wei PK

更新日期：2018-06-27 00:00:00

abstract：:High-altitude-adapted ectotherms can escape competition from dominant species by tolerating low temperatures at cooler elevations, but climate change is eroding such advantages. Studies evaluating broad-scale impacts of global change for high-altitude organisms often overlook the mitigating role of biotic factors. Yet...

journal_title：Scientific reports

authors： Muluvhahothe MM,Joseph GS,Seymour CL,Munyai TC,Foord SH

更新日期：2021-01-08 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Harhay GP,Harhay DM,Bono JL,Capik SF,DeDonder KD,Apley MD,Lubbers BV,White BJ,Larson RL,Smith TPL

更新日期：2020-01-28 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00

abstract：:Radiation weighting factor wR for photons and electrons has been defined as unity independently of the energy of the particles. However, the biological effects depend on the incident energies according to in vitro experimental data. In this study, we have quantified the energy concentration along electron tracks in te...

journal_title：Scientific reports

authors： Yachi Y,Yoshii Y,Matsuya Y,Mori R,Oikawa J,Date H

更新日期：2019-11-27 00:00:00

abstract：:Urinary tract infections (UTIs) are the third most common types of infection in human medicine worldwide. There is increasing appreciation for the pathogenic role of Gram-positive cocci (GPC) in UTIs, as they have a plethora of virulence factors, maintaining their pathogenicity and high affinity for the epithelial cel...

journal_title：Scientific reports

authors： Gajdács M,Ábrók M,Lázár A,Burián K

更新日期：2020-10-19 00:00:00

abstract：:Amorphous thin films from Ge-As-Te system were prepared by pulsed laser deposition to study their intrinsic photostability, morphology, chemical composition, structure and optical properties. Photostability of fabricated layers was studied by spectroscopic ellipsometry within as-deposited as well as relaxed (annealed)...

journal_title：Scientific reports

authors： Hawlová P,Verger F,Nazabal V,Boidin R,Němec P

更新日期：2015-03-23 00:00:00

abstract：:Calcium regulation plays a central role in cardiac function. Several variants in the calcium channel Cav1.2 have been implicated in arrhythmic syndromes. We screened patients with Brugada syndrome, short QT syndrome, early repolarisation syndrome, and idiopathic ventricular fibrillation to determine the frequency and ...

journal_title：Scientific reports

authors： Blancard M,Debbiche A,Kato K,Cardin C,Sabrina G,Gandjbakhch E,Probst V,Haissaguerre M,Extramiana F,Hocini M,Olivier G,Leenhardt A,Guicheney P,Rougier JS

更新日期：2018-10-02 00:00:00