Abstract:
:The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and prognostic value of the RIFLE versus AKIN criteria for AKI in critically ill patients. Literatures were identified by searching Medline, Embase, PubMed, and China National Knowledge Infrastructure (CNKI) database. Nineteen studies with 171,889 participants were included. The pooled estimates of relative risk (RR) were analyzed. We found that the RIFLE and AKIN criteria is different for the incidence of AKI in intensive care unit (ICU) patients (P = 0.02, RR = 0.88), while not for cardiac surgery patients (P = 0.30, RR = 0.93). For AKI-related hospital mortality, the AKIN criteria did not show a better ability in predicting hospital mortality in either ICU (P = 0.19, RR = 1.01) or cardiac surgery patients (P = 0.61, RR = 0.98) compared to RIFLE criteria. Our findings supported that the AKIN criteria can identify more patients in classifying AKI compared to RIFLE criteria, but not showing a better ability in predicting hospital mortality. Moreover, both RIFLE and AKIN criteria for AKI in cardiac surgery patients had better predictive ability compared with the ICU patients.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Xiong J,Tang X,Hu Z,Nie L,Wang Y,Zhao Jdoi
10.1038/srep17917subject
Has Abstractpub_date
2015-12-07 00:00:00pages
17917issn
2045-2322pii
srep17917journal_volume
5pub_type
杂志文章,meta分析abstract::Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery. As human pluripotent stem cell-derived cardiomyocytes remain functionally fetal-type, close monitoring of electrophysiological maturation is critical for their furthe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43210
更新日期:2017-03-07 00:00:00
abstract::Coating of VO2-based thin film has been extensively studied for fabricating energy-saving smart windows. One of the most efficient ways for fabricating high performance films is to create multi-nanolayered structure. However, it has been highly challenge to make such layers in the VO2-based films using conventional me...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23412-4
更新日期:2018-03-28 00:00:00
abstract::The recently described site of Kalinga in the Philippines adds to our understanding of Early-Middle Pleistocene hominin behaviour. Yet, disentangling the natural from the anthropogenic modifications that have taken place in such an old archaeological site is challenging. In this paper we use a set of taphonomic tools ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68066-3
更新日期:2020-07-06 00:00:00
abstract::Two supramolecular complexes of trans-1⊂CB[8] and trans-2⊂CB[8] were successfully achieved by the controlled selective complexation process of cucurbit[8]uril (CB[8]) with hetero-guest pair containing azobenzene and bispyridinium moieties in aqueous solution, exhibiting the reversibly light-driven movements of CB[8] u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04210
更新日期:2014-02-27 00:00:00
abstract::In optical modulation, the highest available modulation rate is basically limited to the GHz frequency range at best. This is because optical modulation is often performed using electro-optic or acousto-optic effects that require application of an external signal to solid-state nonlinear optical materials. Here we des...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20908
更新日期:2016-02-18 00:00:00
abstract::G-protein-coupled receptors (GPCRs) are important drug targets with diverse therapeutic applications. However, there are still more than a hundred orphan GPCRs, whose protein functions and biochemical features remain unidentified. Gpr176 encodes a class-A orphan GPCR that has a role in circadian clock regulation in mo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61370-y
更新日期:2020-03-10 00:00:00
abstract::The structures, stabilities, and electronic properties of monolayer black phosphorus (M-BP) with different kinds of defects are investigated within the frame of density-functional theory. All the possible configurations of defects in M-BP are explored, and the calculated results suggest that the stabilities of the con...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10848
更新日期:2015-06-02 00:00:00
abstract::Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands. Here we investigated the role of OPN in modulating the liver lipidome during regeneration after ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32919-9
更新日期:2018-10-02 00:00:00
abstract::The aim of the current manuscript was to test the applicability of a nanocomposite system of penetration enhancer vesicles (PEVs) within polymeric in situ forming gel network composed of poloxamer and hyaluronic acid for the intranasal delivery of the antiemetic dimenhydrinate (DMH). PEVs were prepared using phospholi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10032-7
更新日期:2017-08-30 00:00:00
abstract::In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43858
更新日期:2017-03-06 00:00:00
abstract::Electric double-layer capacitors (EDLCs) or supercapacitors (SCs) are fast energy storage devices with high pulse efficiency and superior cyclability, which makes them useful in various applications including electronics, vehicles and grids. Aqueous SCs are considered to be more environmentally friendly than those bas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39836
更新日期:2017-01-05 00:00:00
abstract::The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Fl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41906
更新日期:2017-02-06 00:00:00
abstract::Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by overfeeding Artemia. Here we created DIO zebrafish using a different method to induce T2DM. Zebrafish were overfed a commercially available fish food using...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01432-w
更新日期:2017-05-03 00:00:00
abstract::Anti-PD-1 antibodies revolutionized the treatment of advanced melanoma patients. However, one out of three do not respond to this therapy, with an overall poor prognosis. Identification of predictive biomarkers in patients receiving immune-based therapies is necessary for minimizing risk of toxicity and optimizing pat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72711-2
更新日期:2020-10-19 00:00:00
abstract::A feasibility study is presented on the performance parameters of a novel on-chip antenna based on metasurface technology at terahertz band. The proposed metasurface on-chip antenna is constructed on an electrically thin high-permittivity gallium arsenide (GaAs) substrate layer. Metasurface is implemented by engraving...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68105-z
更新日期:2020-07-03 00:00:00
abstract::We demonstrate synthesis of Ni/CuOx/Ni nanowires (NWs) by electrochemical deposition on anodized aluminum oxide (AAO) membranes. AAO with pore diameter of ~70 nm and pore length of ~50 μm was used as the template for synthesis of NWs. After deposition of Au as the seed layer, NWs with a structure of Ni/CuOx/Ni were gr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23069
更新日期:2016-03-15 00:00:00
abstract::Several microbes, including Staphylococcus epidermidis (S. epidermidis), a Gram-positive bacterium, live inside the human nasal cavity as commensals. The role of these nasal commensals in host innate immunity is largely unknown, although bacterial interference in the nasal microbiome may promote ecological competition...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27870
更新日期:2016-06-16 00:00:00
abstract::We presented the unusual result of photobleaching (PB) in Ge-deficient Ge16.8Se83.2 thin films with continuous irradiation with 560 nm laser for 12000 s, which is contradicted with the previous reports that the PB only occurs in GexSe100-x films with x > 30. Observation of the dynamics variations of the photo-induced ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14796-w
更新日期:2017-11-06 00:00:00
abstract::Nowadays, various collaborations are creating immense machines to try to track and understand the origin of high-energy cosmic particles (e.g., IceCube, ANTARES, Baikal-GVD, P-ONE). The detection mechanism of these sophisticated experiments relies mainly on an optical signal generated by the passage of charged particl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68954-8
更新日期:2020-07-24 00:00:00
abstract::Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the two species of chimpanzee and humans. Contra long-accepted ideas, ne...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25262-6
更新日期:2018-05-02 00:00:00
abstract::Drug repositioning strategies have improved substantially in recent years. At present, two advances are poised to facilitate new strategies. First, the LINCS project can provide rich transcriptome data that reflect the responses of cells upon exposure to various drugs. Second, machine learning algorithms have been app...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07705-8
更新日期:2017-08-02 00:00:00
abstract::Understanding the drivers of animal movement is significant for ecology and biology. Yet researchers have so far been unable to fully understand these drivers, largely due to low data resolution. In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotempo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31967
更新日期:2016-08-24 00:00:00
abstract::SLC7A10 (Asc-1) is a sodium-independent amino acid transporter known to facilitate transport of a number of amino acids including glycine, L-serine, L-alanine, and L-cysteine, as well as their D-enantiomers. It has been described as a neuronal transporter with a primary role related to modulation of excitatory glutama...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35592
更新日期:2016-10-19 00:00:00
abstract::Tuberous sclerosis complex (TSC) is a rare autosomal dominant disorder causing benign tumors in the brain and other vital organs. The genes implicated in disease development are TSC1 and TSC2. Here, we have performed mutational analysis followed by a genotype-phenotype correlation study based on the clinical character...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16988-w
更新日期:2017-12-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-56287-0
更新日期:2019-12-19 00:00:00
abstract::Endovascular sealing is a new technique for the repair of abdominal aortic aneurysms. Commercially available in Europe since 2013, it takes a revolutionary approach to aneurysm repair through minimally invasive techniques. Although aneurysm sealing may be thought as more stable than conventional endovascular stent gra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17759-3
更新日期:2017-12-18 00:00:00
abstract::Quantum measurement is a fundamental cornerstone of experimental quantum computations. The main issues in current quantum measurement strategies are the high number of measurement rounds to determine a global optimal measurement output and the low success probability of finding a global optimal measurement output. Eac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43250-2
更新日期:2019-05-01 00:00:00
abstract::The opening of connexin (Cx) hemichannels in the membrane is tightly regulated by calcium (Ca2+) and membrane voltage. Electrophysiological and atomic force microscopy experiments indicate that Ca2+ stabilizes the hemichannel closed state. However, structural data show that Ca2+ binding induces an electrostatic seal p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15975-5
更新日期:2017-11-20 00:00:00
abstract::Hfq is a bacterial RNA binding protein that carries out several roles in genetic expression regulation, mainly at the post-transcriptional level. Previous studies have shown its importance in growth and virulence of bacteria. Here, we provide the direct observation of its ability to interact with membranes. This was e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11157-5
更新日期:2017-09-06 00:00:00
abstract::Animals execute sensorimotor sequences to optimize performance of complex actions series. However, the sensory aspects of these sequences and their dynamic control are often poorly understood. We trained bats to fly to targets at different distances, and analysed their sensory behavior before and during flight to test...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00543-8
更新日期:2017-03-28 00:00:00