Cortisol metabolism in pregnancies with small for gestational age neonates.

abstract：:While implicated in therapeutic resistance, malignant progenitor cell cycle kinetics have been difficult to quantify in real-time. We developed an efficient lentiviral bicistronic fluorescent, ubiquitination-based cell cycle indicator reporter (Fucci2BL) to image live single progenitors on a defined niche coupled with...

journal_title：Scientific reports

authors： Pineda G,Lennon KM,Delos Santos NP,Lambert-Fliszar F,Riso GL,Lazzari E,Marra MA,Morris S,Sakaue-Sawano A,Miyawaki A,Jamieson CH

更新日期：2016-04-04 00:00:00

abstract：:Unlike mammals, in palmipedes de novo lipogenesis from diet takes place mostly in the liver. The French Landes Goose is famous for its high capacity and susceptibility to fatty liver production. While miRNAs play a critical role in the posttranscriptional regulation of gene expression, miRNAs that are involved in the ...

journal_title：Scientific reports

authors： Chen F,Zhang H,Li J,Tian Y,Xu J,Chen L,Wei J,Zhao N,Yang X,Zhang W,Lu L

更新日期：2017-11-24 00:00:00

abstract：:During inflammatory response, blood leukocytes adhere to the endothelium. This process involves numerous adhesion molecules, including a transmembrane chemokine, CX3CL1, which behaves as a molecular cluster. How this cluster assembles and whether this association has a functional role remain unknown. The analysis of C...

journal_title：Scientific reports

authors： Ostuni MA,Hermand P,Saindoy E,Guillou N,Guellec J,Coens A,Hattab C,Desuzinges-Mandon E,Jawhari A,Iatmanen-Harbi S,Lequin O,Fuchs P,Lacapere JJ,Combadière C,Pincet F,Deterre P

更新日期：2020-06-03 00:00:00

abstract：:A simple, environmentally friendly and cost-effective nonsurfactant template method was used to synthesize tannic-acid-templated mesoporous silica nanoparticles (TMSNs), and then dopamine functionalized TMSNs (Dop-TMSNs) which was synthesized by a facile and biomimetic coating strategy, was developed as a new sorbent ...

journal_title：Scientific reports

authors： Gao J,Lei H,Han Z,Shi Q,Chen Y,Jiang Y

更新日期：2017-03-22 00:00:00

abstract：:Pulse generation often requires a stabilized cavity and its corresponding mode structure for initial phase-locking. Contrastingly, modeless cavity-free random lasers provide new possibilities for high quantum efficiency lasing that could potentially be widely tunable spectrally and temporally. Pulse generation in rand...

journal_title：Scientific reports

authors： Yao BC,Rao YJ,Wang ZN,Wu Y,Zhou JH,Wu H,Fan MQ,Cao XL,Zhang WL,Chen YF,Li YR,Churkin D,Turitsyn S,Wong CW

更新日期：2015-12-21 00:00:00

abstract：:The manuscript highlights the efficacy of silver ions to act as a unique probe for the detection of bacterial contamination in water samples. The bacterial cell membrane adherence property of the silver ions was employed to develop two different bacterial detection assays employing colorimetric and electrochemical tec...

journal_title：Scientific reports

authors： Kumar V,Chopra A,Bisht B,Bhalla V

更新日期：2020-07-20 00:00:00

abstract：:The shape of fragments generated by the breakup of solids is central to a wide variety of problems ranging from the geomorphic evolution of boulders to the accumulation of space debris orbiting Earth. Although the statistics of the mass of fragments has been found to show a universal scaling behavior, the comprehensiv...

journal_title：Scientific reports

authors： Domokos G,Kun F,Sipos AÁ,Szabó T

更新日期：2015-03-16 00:00:00

abstract：:The Kidney Donor Profile Index (KDPI) was introduced in the United States in 2014 to guide the decision making of clinicians with respect to accepting or declining a donated kidney. To evaluate whether the KDPI can be applied to a European cohort, we retrospectively assessed 580 adult patients who underwent renal tran...

journal_title：Scientific reports

authors： Dahmen M,Becker F,Pavenstädt H,Suwelack B,Schütte-Nütgen K,Reuter S

更新日期：2019-08-02 00:00:00

abstract：:The growth in energy devices and the role of supercapacitors are increasingly important in today's world. Designing an electrode material for supercapacitors using metals that have high performance, superior structure, are eco-friendly, inexpensive and highly abundant is essentially required for commercialization. In ...

journal_title：Scientific reports

authors： Isacfranklin M,Yuvakkumar R,Ravi G,Hong SI,Shini F,Thambidurai M,Dang C,Velauthapillai D

更新日期：2020-11-05 00:00:00

abstract：:In resampling methods, such as bootstrapping or cross validation, a very similar computational problem (usually an optimization procedure) is solved over and over again for a set of very similar data sets. If it is computationally burdensome to solve this computational problem once, the whole resampling method can bec...

journal_title：Scientific reports

authors： Mestdagh M,Verdonck S,Duisters K,Tuerlinckx F

更新日期：2015-11-24 00:00:00

abstract：:Understanding adipose tissue cellular heterogeneity and homeostasis is essential to comprehend the cell type dynamics in metabolic diseases. Cellular subpopulations in the adipose tissue have been related to disease development, but efforts towards characterizing the adipose tissue cell type composition are limited. H...

journal_title：Scientific reports

authors： Lenz M,Arts ICW,Peeters RLM,de Kok TM,Ertaylan G

更新日期：2020-06-26 00:00:00

abstract：:Natural infection with measles virus (MV) establishes lifelong immunity. Persistent infection with MV is likely involved in this phenomenon, as non-replicating protein antigens never induce such long-term immunity. Although MV establishes stable persistent infection in vitro and possibly in vivo, the mechanism by whic...

journal_title：Scientific reports

authors： Doi T,Kwon HJ,Honda T,Sato H,Yoneda M,Kai C

更新日期：2016-11-24 00:00:00

abstract：:With the continuous urbanization and industrialization in the world, energy saving and greenhouse gas (GHG) emission reduction have been serious issues to be addressed, for which heat recovery from traditional energy-intensive industries makes up a significant strategy. Here we report a novel approach to extract the w...

journal_title：Scientific reports

authors： Sun Y,Sridhar S,Liu L,Wang X,Zhang Z

更新日期：2015-11-12 00:00:00

abstract：:In response to ER stress, activating transcription factor 6 (ATF6) traffics from ER to Golgi apparatus where it is activated by cleavage before being translocated as transcription factor to the cell nucleus. In this work we describe ATF6α as a newly target of the aspirin metabolite sodium salicylate (NaSal). NaSal tre...

journal_title：Scientific reports

authors： Mügge FLB,Silva AM

更新日期：2017-08-23 00:00:00

abstract：:Viewing facial expressions often evokes facial responses in the observer. These spontaneous facial reactions (SFRs) are believed to play an important role for social interactions. However, their developmental trajectory and the underlying neurocognitive mechanisms are still little understood. In the current study, 4- ...

journal_title：Scientific reports

authors： Kaiser J,Crespo-Llado MM,Turati C,Geangu E

更新日期：2017-12-13 00:00:00

abstract：:We set out to determine the usability of serum neurofilament light chain (sNfL), serum glial fibrillary acidic protein (sGFAP), and retinal parameters by using optical coherence tomography (OCT) as reliable biomarkers of the progression of oxaliplatin-induced peripheral neuropathy (OIPN). Forty-three patients schedule...

journal_title：Scientific reports

authors： Kim SH,Choi MK,Park NY,Hyun JW,Lee MY,Kim HJ,Jung SK,Cha Y

更新日期：2020-05-14 00:00:00

abstract：:Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated the spindle assembly checkpoint component BUB1 and the mitotic cohesin SMC1A, and...

journal_title：Scientific reports

authors： Andriani GA,Almeida VP,Faggioli F,Mauro M,Tsai WL,Santambrogio L,Maslov A,Gadina M,Campisi J,Vijg J,Montagna C

更新日期：2016-10-12 00:00:00

abstract：:Peritoneal macrophages play a critical role in the control of infectious and inflammatory diseases. Although recent progress on murine peritoneal macrophages has revealed multiple aspects on their origin and mechanisms involved in their maintenance in this compartment, little is known on the characteristics of human p...

journal_title：Scientific reports

authors： Ruiz-Alcaraz AJ,Carmona-Martínez V,Tristán-Manzano M,Machado-Linde F,Sánchez-Ferrer ML,García-Peñarrubia P,Martínez-Esparza M

更新日期：2018-08-24 00:00:00

abstract：:Recovery of nutrients and energy from municipal wastewater has attracted much attention in recent years; however, its efficiency is significantly limited by the low-strength properties of municipal wastewater. Herein, we report a pilot-scale forward osmosis (FO) system using a spiral-wound membrane module to concentra...

journal_title：Scientific reports

authors： Wang Z,Zheng J,Tang J,Wang X,Wu Z

更新日期：2016-02-22 00:00:00

abstract：:Previous reports on epigenetic mechanisms involved in alcohol abuse have focus on hepatic and neuronal regions, leaving the immune system and specifically monocyte-derived dendritic cells (MDDCs) understudied. Our lab has previously shown histone deacetylases are modulated in cells derived from alcohol users and after...

journal_title：Scientific reports

authors： Parira T,Figueroa G,Laverde A,Casteleiro G,Gomez Hernandez ME,Fernandez-Lima F,Agudelo M

更新日期：2017-09-11 00:00:00

abstract：:Glomerular mesangial cell (GMC) proliferation and matrix expansion are pathological hallmarks of a wide range of kidney diseases, including diabetic nephropathy. Although the circulating level of peptide hormone urotensin II (UII) and kidney tissue expression of UII and UII receptors (UTR) are increased in diabetic ne...

journal_title：Scientific reports

authors： Soni H,Adebiyi A

更新日期：2017-12-22 00:00:00

abstract：:Honey bees (Apis mellifera) are important pollinators and their health is threatened worldwide by persistent exposure to a wide range of factors including pesticides, poor nutrition, and pathogens. Nosema ceranae is a ubiquitous microsporidian associated with high colony mortality. We used lab micro-colonies of honey ...

journal_title：Scientific reports

authors： Lecocq A,Jensen AB,Kryger P,Nieh JC

更新日期：2016-02-25 00:00:00

abstract：:We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21)  W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...

journal_title：Scientific reports

authors： Faenov AY,Colgan J,Hansen SB,Zhidkov A,Pikuz TA,Nishiuchi M,Pikuz SA,Skobelev IY,Abdallah J,Sakaki H,Sagisaka A,Pirozhkov AS,Ogura K,Fukuda Y,Kanasaki M,Hasegawa N,Nishikino M,Kando M,Watanabe Y,Kawachi T,Masuda S

更新日期：2015-09-02 00:00:00

abstract：:E. coli of the phylogenetic group B2 harbouring Extra intestinal Pathogenic Escherichia coli (ExPEC) genes are frequently seen as colonizers of the intestine in patients with active ulcerative colitis (UC). In this study, we describe the influence of E. coli Nissle (EcN) B2 as add-on treatment to conventional therapie...

journal_title：Scientific reports

authors： Mirsepasi-Lauridsen HC,Halkjaer SI,Mortensen EM,Lydolph MC,Nordgaard-Lassen I,Krogfelt KA,Petersen AM

更新日期：2016-09-30 00:00:00

abstract：:Early diagnosis of hepatocellular carcinoma (HCC) remains challenging to date. Characteristic metabolic deregulations of HCC may enable novel biomarkers discovery for early diagnosis. A capillary electrophoresis-time of flight mass spectrometry (CE-TOF/MS)-based metabolomics approach was performed to discover and vali...

journal_title：Scientific reports

authors： Zeng J,Huang X,Zhou L,Tan Y,Hu C,Wang X,Niu J,Wang H,Lin X,Yin P

更新日期：2015-11-03 00:00:00

abstract：:The growing interest in engineered tumor models prompted us to devise a method for the non-invasive assessment of such models. Here, we report on bioluminescence imaging (BLI) for the assessment of engineered tumor models in the fertilized chicken egg, i.e, chick chorioallantoic membrane (CAM) assay. One prostate canc...

journal_title：Scientific reports

authors： Jefferies B,Lenze F,Sathe A,Truong N,Anton M,von Eisenhart-Rothe R,Nawroth R,Mayer-Kuckuk P

更新日期：2017-07-10 00:00:00

abstract：:The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to RGPs. Here we find that GPR157, an orphan G protein-coupled receptor, localizes to RGPs' primary cilia exposed to the cerebrospinal fluid (CSF). GPR157 couples wi...

journal_title：Scientific reports

authors： Takeo Y,Kurabayashi N,Nguyen MD,Sanada K

更新日期：2016-05-04 00:00:00

abstract：:Insecticide-treated nets (ITNs) remain major components for vector control despite the spread of resistance mechanisms among mosquito populations. Multiple exposures to pyrethroids may induce physiological and behavioral changes in mosquitoes, possibly reducing efficacy of control tools. Despite epidemiological releva...

journal_title：Scientific reports

authors： Mulatier M,Pennetier C,Porciani A,Chandre F,Dormont L,Cohuet A

更新日期：2019-06-03 00:00:00

abstract：:Thaumarchaeota and the gene encoding for a subunit of ammonia monooxygenase (amoA) are ubiquitous in Polar Seas, and some Thaumarchaeota also have a gene coding for ureC, diagnostic for urease. Using quantitative PCR we investigated the occurrence of genes and transcripts of ureC and amoA in Arctic samples from winter...

journal_title：Scientific reports

authors： Pedneault E,Galand PE,Potvin M,Tremblay JÉ,Lovejoy C

更新日期：2014-04-11 00:00:00

abstract：:Extracellular vesicles (EVs) have important roles in physiology, pathology, and more recently have been identified as efficient carriers of therapeutic cargoes. For efficient study of EVs, a single-step, rapid and scalable isolation strategy is necessary. Chromatography techniques are widely used for isolation of biol...

journal_title：Scientific reports

authors： Heath N,Grant L,De Oliveira TM,Rowlinson R,Osteikoetxea X,Dekker N,Overman R

更新日期：2018-04-10 00:00:00