Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac.

abstract：:Vanadium doped ZnO (VZO) thin films were grown by RF magnetron sputtering, starting from a ZnO:V ceramic target. The crystal structure, chemical composition, electric and piezoelectric properties of the films were investigated either on the as-grown thin films or after a post-deposition rapid thermal annealing (RTA) t...

journal_title：Scientific reports

authors： Laurenti M,Castellino M,Perrone D,Asvarov A,Canavese G,Chiolerio A

更新日期：2017-02-06 00:00:00

abstract：:Breast cancer is a major cause of cancer mortality worldwide. Fascin-1 (FSCN1) is an actin-binding protein found in mammalian cells, including endothelial, neuronal and mesenchymal cells. FSCN1 overexpression has been indicated in breast cancer patients. However, scant information is available regarding the associatio...

journal_title：Scientific reports

authors： Wang CQ,Tang CH,Wang Y,Jin L,Wang Q,Li X,Hu GN,Huang BF,Zhao YM,Su CM

更新日期：2017-11-21 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Kim MS,Jeong J,Seo J,Kim HS,Kim SJ,Jin W

更新日期：2020-07-06 00:00:00

abstract：:Ghrelin and obestatin are two gastrointestinal peptides, derived from a common precursor. Expression of both peptides have been found in breast cancer tissue and ghrelin has been associated with breast cancer development. Ghrelin expression is associated with longer survival in women diagnosed with invasive and node n...

journal_title：Scientific reports

authors： Grönberg M,Nilsson C,Markholm I,Hedenfalk I,Blomqvist C,Holmberg L,Tiensuu Janson E,Fjällskog ML

更新日期：2018-09-11 00:00:00

abstract：:Microvascular endothelial cell heterogeneity and its relationship to hemodynamics remains poorly understood due to a lack of sufficient methods to examine these parameters in vivo at high resolution throughout an angiogenic network. The availability of surrogate markers for functional vascular proteins, such as green ...

journal_title：Scientific reports

authors： Kelly-Goss MR,Ning B,Bruce AC,Tavakol DN,Yi D,Hu S,Yates PA,Peirce SM

更新日期：2017-08-22 00:00:00

abstract：:Respiratory syncytial virus (RSV) is an important cause of serious lower respiratory tract disease in infants. Several studies have shown evidence pointing to the genome of the host as an important factor determining susceptibility to respiratory disease caused by RSV. We sequenced the complete exomes of 54 patients i...

journal_title：Scientific reports

authors： Salas A,Pardo-Seco J,Cebey-López M,Gómez-Carballa A,Obando-Pacheco P,Rivero-Calle I,Currás-Tuala MJ,Amigo J,Gómez-Rial J,Martinón-Torres F,GENDRES network.

更新日期：2017-11-21 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:Alternative splicing contributes to phenotypic diversity at multiple biological scales, and its dysregulation is implicated in both ageing and age-associated diseases in human. Cross-tissue variability in splicing further complicates its links to age-associated phenotypes and elucidating these links requires a compreh...

journal_title：Scientific reports

authors： Wang K,Wu D,Zhang H,Das A,Basu M,Malin J,Cao K,Hannenhalli S

更新日期：2018-07-19 00:00:00

abstract：:Despite the unique nature of endemic species, their origin and population history remain poorly studied. We investigated the population history of 28 coral reef fish species, close related, from the Gambier and Marquesas Islands, from five families, with range size varying from widespread to small-range endemic. We an...

journal_title：Scientific reports

authors： Delrieu-Trottin E,Mona S,Maynard J,Neglia V,Veuille M,Planes S

更新日期：2017-01-16 00:00:00

abstract：:Mitochondrial disorders are among the most prevalent inborn errors of metabolism but largely lack treatments and have poor outcomes. High-fat, low-carbohydrate ketogenic diets (KDs) have shown beneficial effects in mouse models of mitochondrial myopathies, with induction of mitochondrial biogenesis as the suggested ma...

journal_title：Scientific reports

authors： Purhonen J,Rajendran J,Mörgelin M,Uusi-Rauva K,Katayama S,Krjutskov K,Einarsdottir E,Velagapudi V,Kere J,Jauhiainen M,Fellman V,Kallijärvi J

更新日期：2017-04-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： McCloskey MC,Shaheen S,Rabago L,Hulverson MA,Choi R,Barrett LK,Arnold SLM

更新日期：2020-02-11 00:00:00

abstract：:Infection after renal transplantation remains a major cause of morbidity and death, especially infection from the extensively drug-resistant bacteria, A. baumannii. A total of fourteen A. baumannii isolates were isolated from the donors' preserved fluid from DCD (donation after cardiac death) renal transplantation and...

journal_title：Scientific reports

authors： Jiang H,Cao L,Qu L,Qu T,Liu G,Wang R,Li B,Wang Y,Ying C,Chen M,Lu Y,Feng S,Xiao Y,Wang J,Wu J,Chen J

更新日期：2017-05-16 00:00:00

abstract：:Despite increasing work detailing the presence of foraging specializations across a range of taxa, limited attention so far has been given to the role of spatiotemporal variation in food predictability in shaping individual resource selection. Here, we studied the exploitation of human-provided carrion resources diffe...

journal_title：Scientific reports

authors： van Overveld T,García-Alfonso M,Dingemanse NJ,Bouten W,Gangoso L,de la Riva M,Serrano D,Donázar JA

更新日期：2018-10-11 00:00:00

abstract：:Knee osteoarthritis (KOA) is reported to have characteristic kinematics during walking. However, the relationship between Kellgren-Lawrence (K/L) score and the 3D kinematic gait of patients with medial KOA remains unclear. Here, ninety-seven patients with medial KOA and thirty-eight asymptomatic participants were invo...

journal_title：Scientific reports

authors： Zeng X,Ma L,Lin Z,Huang W,Huang Z,Zhang Y,Mao C

更新日期：2017-06-22 00:00:00

abstract：:The mechanistic target of rapamycin (mTOR) is a central mediator of protein synthesis in skeletal muscle. We utilized immunofluorescence approaches to study mTOR cellular distribution and protein-protein co-localisation in human skeletal muscle in the basal state as well as immediately, 1 and 3 h after an acute bout o...

journal_title：Scientific reports

authors： Song Z,Moore DR,Hodson N,Ward C,Dent JR,O'Leary MF,Shaw AM,Hamilton DL,Sarkar S,Gangloff YG,Hornberger TA,Spriet LL,Heigenhauser GJ,Philp A

更新日期：2017-07-10 00:00:00

abstract：:Although plants are essentially sessile in nature, these organisms are very much in tune with their environment and are capable of a variety of movements. This may come as a surprise to many non-botanists, but not to Charles Darwin, who reported that plants do produce movements. Following Darwin's specific interest on...

journal_title：Scientific reports

authors： Guerra S,Peressotti A,Peressotti F,Bulgheroni M,Baccinelli W,D'Amico E,Gómez A,Massaccesi S,Ceccarini F,Castiello U

更新日期：2019-11-12 00:00:00

abstract：:A lack of exercise leads to being overweight or obese affecting regional brain structure and functional connectivity associated with impaired cognitive function and dementia. In recent decades, several studies of healthy individuals suggest that adiposity may also produce negative independent effects on the brain. We ...

journal_title：Scientific reports

authors： Cárdenas D,Madinabeitia I,Vera J,de Teresa C,Alarcón F,Jiménez R,Catena A

更新日期：2020-01-17 00:00:00

abstract：:Emergence of resistant Plasmodium species makes drug efficacy testing a crucial part of malaria control. Here we describe a novel assay for sensitive, fast and simple drug screening via the magneto-optical detection of hemozoin, a natural biomarker formed during the hemoglobin metabolism of Plasmodium species. By quan...

journal_title：Scientific reports

authors： Molnár P,Orbán Á,Izrael R,Babai R,Marton L,Butykai Á,Karl S,Vértessy BG,Kézsmárki I

更新日期：2020-08-20 00:00:00

abstract：:A spontaneous exchange bias (SEB) discovered by Wang et al. [Phys. Rev. Lett. 106 (2011) 077203.] after zero-field cooling (ZFC) has attracted recent attention due to its interesting physics. In this letter, we report a giant SEB tuned by Sb-doping in Ni50Mn38Ga12-xSbx Heusler alloys. Such an SEB was switched on below...

journal_title：Scientific reports

authors： Tian F,Cao K,Zhang Y,Zeng Y,Zhang R,Chang T,Zhou C,Xu M,Song X,Yang S

更新日期：2016-08-01 00:00:00

abstract：:Platelet-driven reduction in blood clot volume (clot contraction or retraction) has been implicated to play a role in hemostasis and thrombosis. Although these processes are often linked with inflammation, the role of inflammatory cells in contraction of blood clots and thrombi has not been investigated. The aim of th...

journal_title：Scientific reports

authors： Peshkova AD,Le Minh G,Tutwiler V,Andrianova IA,Weisel JW,Litvinov RI

更新日期：2017-07-11 00:00:00

abstract：:Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only Rnasel-1 and Rnasel-...

journal_title：Scientific reports

authors： Ferguson R,Holloway DE,Chandrasekhar A,Acharya KR,Subramanian V

更新日期：2019-02-01 00:00:00

abstract：:To match the relentless pursuit of three research hot points - efficient solar utilization, green and sustainable remediation of wastewater and advanced oxidation processes, solar-mediated thermo-electrochemical oxidation of surfactant was proposed and developed for green remediation of surfactant wastewater. The sola...

journal_title：Scientific reports

authors： Gu D,Gao S,Jiang T,Wang B

更新日期：2017-03-15 00:00:00

abstract：:The amphibian chytrid fungus Batrachochytrium dendrobatidis is an emerging infectious pathogen present on every continent except Antarctica. It causes the disease chytridiomycosis in a subset of species but does not always result in disease or death for every host. Ambient temperature influences both amphibian metabol...

journal_title：Scientific reports

authors： Campbell L,Bower DS,Clulow S,Stockwell M,Clulow J,Mahony M

更新日期：2019-01-14 00:00:00

abstract：:The increasing availability of electronic health care records has provided remarkable progress in the field of population health. In particular the identification of disease risk factors has flourished under the surge of available data. Researchers can now access patient data across a broad range of demographics and g...

journal_title：Scientific reports

authors： Feldman K,Stiglic G,Dasgupta D,Kricheff M,Obradovic Z,Chawla NV

更新日期：2016-07-27 00:00:00

abstract：:We report a small molecule tandem organic photovoltaic (OPV) cell with a high power conversion efficiency (PCE) of 7.27%. This cell contains two subcells with an identical mixed active layer of C70:5 wt%TAPC (1,1-bis-(4-bis(4-methyl-phenyl)-amino-phenyl)-cyclohexane). The performance was dramatically improved by simpl...

journal_title：Scientific reports

authors： Gao Y,Jin F,Li W,Su Z,Chu B,Wang J,Zhao H,Wu H,Liu C,Hou F,Lin T,Song Q

更新日期：2016-04-01 00:00:00

abstract：:In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. Th...

journal_title：Scientific reports

authors： Wang W,Chu ST,Little BE,Pasquazi A,Wang Y,Wang L,Zhang W,Wang L,Hu X,Wang G,Hu H,Su Y,Li F,Liu Y,Zhao W

更新日期：2016-06-24 00:00:00

abstract：:FAS rs2234767 (-1377 G>A), rs1800682 (-670 A>G) and FASLG rs763110 (-844 C>T) promoter polymorphisms can influence transcriptional activities of the genes and thus multiple tumors susceptibility. To investigate their association with risk of colorectal cancer (CRC), the three SNPs were genotyped in 878 cases and 884 c...

journal_title：Scientific reports

authors： Wang S,Wu S,Meng Q,Li X,Zhang J,Chen R,Wang M

更新日期：2016-01-13 00:00:00

abstract：:Despite recent advances in cancer management and therapy, resistance to cytotoxic medications remains a major clinical challenge; hence, combination-based anti-cancer treatment regimens are currently gaining momentum. PTC-209 reduced BMI1 protein expression, while palbociclib inhibited CDK4, Rb, and pRbSer795 protein ...

journal_title：Scientific reports

authors： Elango R,Vishnubalaji R,Manikandan M,Binhamdan SI,Siyal AA,Alshawakir YA,Alfayez M,Aldahmash A,Alajez NM

更新日期：2019-09-23 00:00:00

abstract：:Next generation sequencing panels have been developed for hereditary cancer, although there is some debate about their cost-effectiveness compared to exome sequencing. The performance of two panels is compared to exome sequencing. Twenty-four patients were selected: ten with identified mutations (control set) and four...

journal_title：Scientific reports

authors： Feliubadaló L,Tonda R,Gausachs M,Trotta JR,Castellanos E,López-Doriga A,Teulé À,Tornero E,Del Valle J,Gel B,Gut M,Pineda M,González S,Menéndez M,Navarro M,Capellá G,Gut I,Serra E,Brunet J,Beltran S,Lázaro C

更新日期：2017-01-04 00:00:00

abstract：:Phosphorylation plays important roles in several processes including synaptic plasticity and memory. The critical role of extracellular signal-regulated kinase (ERK) in these processes is well established. ERK is activated in a sustained manner by different stimuli. However, the mechanisms of sustained ERK activation ...

journal_title：Scientific reports

authors： Maharana C,Sharma KP,Sharma SK

更新日期：2013-01-01 00:00:00