Abstract:
:A lack of exercise leads to being overweight or obese affecting regional brain structure and functional connectivity associated with impaired cognitive function and dementia. In recent decades, several studies of healthy individuals suggest that adiposity may also produce negative independent effects on the brain. We aimed to investigate the relationship between body composition - total fat mass (TFM) and visceral adipose tissue (VAT) - with white matter (WM) integrity using a whole-brain approach in military pilots. Twenty-three military helicopter pilots (Mage = 36.79; SD = 8.00; MBMI = 25.48; SD = 2.49) took part in the study. Brain volumes were studied using diffusion tensor imaging technique by means of a 3T Magnetom Tim Trio. Measurements of body mass index (BMI), TFM and VAT were obtained using Dual-energy X-ray Absorptiometry (DXA). The results showed that, on one hand, higher TFM was associated with higher white matter fractional anisotropy (FA) and, on the other hand, higher VAT was associated with lower FA. Data showed that TFM and VAT are the critical factors underlying WM integrity in combat helicopter pilots. The authors suggest that fat presence enhance brain connectivity while there is no excess, specifically in VAT.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Cárdenas D,Madinabeitia I,Vera J,de Teresa C,Alarcón F,Jiménez R,Catena Adoi
10.1038/s41598-019-57345-3subject
Has Abstractpub_date
2020-01-17 00:00:00pages
610issue
1issn
2045-2322pii
10.1038/s41598-019-57345-3journal_volume
10pub_type
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