Author Correction: Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri.

abstract：:Earlier studies showed that endogenous estrogens have neuroprotective effect against oxidative damage. The present study seeks to investigate the protective effect of various endogenous estrogen metabolites against oxidative neurotoxicity in vitro and in vivo. Using immortalized mouse hippocampal neuronal cells as an ...

journal_title：Scientific reports

authors： Choi HJ,Lee AJ,Kang KS,Song JH,Zhu BT

更新日期：2020-04-29 00:00:00

abstract：:Mankind is on the verge of a postantibiotic era. New concepts are needed in our battle to attenuate infectious diseases around the world and broad spectrum plant-inspired synergistic pharmaceutical preparations should find their place in the global fight against pathogenic microorganisms. To progress towards the disco...

journal_title：Scientific reports

authors： Rodrigues AMS,Eparvier V,Odonne G,Amusant N,Stien D,Houël E

更新日期：2019-06-19 00:00:00

abstract：:Plant health is strongly connected with plants´ microbiome. In case of raw-eaten plants, the microbiome can also affect human health. To study potential impacts on health issues of both hosts, the microbiome composition of seven different Brassica vegetables, originating from different food processing pathways, was an...

journal_title：Scientific reports

authors： Wassermann B,Rybakova D,Müller C,Berg G

更新日期：2017-12-15 00:00:00

abstract：:Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density. Allom...

journal_title：Scientific reports

authors： Ma L,Shen C,Lou D,Fu S,Guan D

更新日期：2017-10-13 00:00:00

abstract：:The temperature dependence of the resistivity (ρ) of Ag-doped Bi2Se3 (AgxBi2-xSe3) shows insulating behavior above 35 K, but below 35 K, ρ suddenly decreases with decreasing temperature, in contrast to the metallic behavior for non-doped Bi2Se3 at 1.5-300 K. This significant change in transport properties from metalli...

journal_title：Scientific reports

authors： Uesugi E,Uchiyama T,Goto H,Ota H,Ueno T,Fujiwara H,Terashima K,Yokoya T,Matsui F,Akimitsu J,Kobayashi K,Kubozono Y

更新日期：2019-03-29 00:00:00

abstract：:Early fMRI studies suggested that brain areas processing self-related and other-related information were highly overlapping. Hypothesising functional localisation of the cortex, researchers have tried to locate "self-specific" and "other-specific" regions within these overlapping areas by subtracting suspected confoun...

journal_title：Scientific reports

authors： Chen YA,Huang TR

更新日期：2017-03-03 00:00:00

abstract：:During bipedal walking, modern humans dorsiflex their forefoot at the metatarsophalangeal joints (MTPJs) prior to push off, which tightens the plantar soft tissues to convert the foot into a stiff propulsive lever. Particular features of metatarsal head morphology such as "dorsal doming" are thought to facilitate this...

journal_title：Scientific reports

authors： Fernández PJ,Holowka NB,Demes B,Jungers WL

更新日期：2016-07-28 00:00:00

abstract：:In photosynthesis Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyses the often rate limiting CO2-fixation step in the Calvin cycle. This makes Rubisco both the gatekeeper for carbon entry into the biosphere and a target for functional improvement to enhance photosynthesis and plant growth. Encumbering...

journal_title：Scientific reports

authors： Wilson RH,Alonso H,Whitney SM

更新日期：2016-03-01 00:00:00

abstract：:Fibrocystic breast change (FBC) is extremely common and occurrs in 90% of women during their lives. The association between body composition and risk of breast cancer is well established. We hypothesized that the effect might exist during the development of FBC. Our aim was to examine the relationships of total lean m...

journal_title：Scientific reports

authors： Chen YY,Fang WH,Wang CC,Kao TW,Chang YW,Yang HF,Wu CJ,Sun YS,Chen WL

更新日期：2018-06-15 00:00:00

abstract：:Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. The relation of bacterial factors and unfavorable outcomes remains controversial. We retrospectively reviewed clinical data of patients with bacteremia caused by MRSA with vancomycin MIC ...

journal_title：Scientific reports

authors： Yang CC,Sy CL,Huang YC,Shie SS,Shu JC,Hsieh PH,Hsiao CH,Chen CJ

更新日期：2018-05-18 00:00:00

abstract：:Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition from a highly specialized oocyte to a pluripotent embryo. Depletion of these maternally-encoded transcripts fr...

journal_title：Scientific reports

authors： Mahadevan S,Sathappan V,Utama B,Lorenzo I,Kaskar K,Van den Veyver IB

更新日期：2017-03-20 00:00:00

abstract：:Traditional strengthening ways, such as strain, precipitation, and solid-solution, come into effect by pinning the motion of dislocation. Here, through first-principles calculations we report on an extra-electron induced covalent strengthening mechanism, which alters chemical bonding upon the introduction of extra-val...

journal_title：Scientific reports

authors： Niu H,Chen XQ,Liu P,Xing W,Cheng X,Li D,Li Y

更新日期：2012-01-01 00:00:00

abstract：:The tumour suppressor p53 is mutated in cancer, including over 96% of high-grade serous ovarian cancer (HGSOC). Mutations cause loss of wild-type p53 function due to either gain of abnormal function of mutant p53 (mutp53), or absent to low mutp53. Massively parallel sequencing (MPS) enables increased accuracy of detec...

journal_title：Scientific reports

authors： Cole AJ,Dwight T,Gill AJ,Dickson KA,Zhu Y,Clarkson A,Gard GB,Maidens J,Valmadre S,Clifton-Bligh R,Marsh DJ

更新日期：2016-05-18 00:00:00

abstract：:The nutrient ecological stoichiometry of plants and soil is important for the growth and dynamics of species, but the stoichiometric relationships among leaf, litter, and soil remain poorly understood. We analyzed the carbon (C), nitrogen (N), and phosphorus (P) stoichiometry of the leaves, litter, and soil for 31 spe...

journal_title：Scientific reports

authors： Zhang G,Zhang P,Peng S,Chen Y,Cao Y

更新日期：2017-09-18 00:00:00

abstract：:The concentration of CO2 in many aquatic systems is variable, often lower than the KM of the primary carboxylating enzyme Rubisco, and in order to photosynthesize efficiently, many algae operate a facultative CO2 concentrating mechanism (CCM). Here we measured the responses of a marine diatom, Thalassiosira pseudonana...

journal_title：Scientific reports

authors： Clement R,Lignon S,Mansuelle P,Jensen E,Pophillat M,Lebrun R,Denis Y,Puppo C,Maberly SC,Gontero B

更新日期：2017-02-09 00:00:00

abstract：:Although there is evidence that non-steroidal anti-inflammatory drugs (NSAIDs) might be able to prevent pancreatic cancer, the findings from epidemiological studies have been inconsistent. In this paper, we conducted a meta-analysis of observational studies to examine this possibility. We searched PubMed and Embase fo...

journal_title：Scientific reports

authors： Zhang YP,Wan YD,Sun YL,Li J,Zhu RT

更新日期：2015-10-21 00:00:00

abstract：:KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current study aimed to design a...

journal_title：Scientific reports

authors： Schelleckes K,Schmitz B,Lenders M,Mewes M,Brand SM,Brand E

更新日期：2018-03-09 00:00:00

abstract：:No consensus currently exist on the optimal treatment of patients with high-risk nonmuscle invasive (HGT1) micropapillary variant of bladder cancer (MPBC). Transcripsome analysis may allow stratification of MPBC-HGT1 enabling prediction of recurrence and guide therapeutic management for individual patients. Whole tran...

journal_title：Scientific reports

authors： Bowden M,Nadal R,Zhou CW,Werner L,Barletta J,Juanpere N,Lloreta J,Hernandez-Llodrà S,Morote J,de Torres I,Orsola A,Cejas P,Long H,Bellmunt J

更新日期：2020-11-18 00:00:00

abstract：:Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals. The microbiome has circadian rhythmicity and helps the host circadian clock function. We investigated the ef...

journal_title：Scientific reports

authors： Tahara Y,Yamazaki M,Sukigara H,Motohashi H,Sasaki H,Miyakawa H,Haraguchi A,Ikeda Y,Fukuda S,Shibata S

更新日期：2018-01-23 00:00:00

abstract：:A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vitro. In addition, oral administration of an APD in a rabbit model of ...

journal_title：Scientific reports

authors： Ottosson H,Nylén F,Sarker P,Miraglia E,Bergman P,Gudmundsson GH,Raqib R,Agerberth B,Strömberg R

更新日期：2016-11-09 00:00:00

abstract：:NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to describe differences i...

journal_title：Scientific reports

authors： Nava M,Dutta P,Farias-Eisner R,Vadgama JV,Wu Y

更新日期：2019-03-26 00:00:00

abstract：:Conflicting results of survival outcomes for primary and secondary muscle-invasive bladder cancer (MIBC) have been reported in previous studies. Primary MIBC is defined as presentation of muscle-invasive disease at initial diagnosis while secondary MIBC presumes that non-muscle invasive disease later progressed to MIB...

journal_title：Scientific reports

authors： Ge P,Wang L,Lu M,Mao L,Li W,Wen R,Lin J,Wang J,Chen J

更新日期：2018-05-15 00:00:00

abstract：:Biological functions of hyaluronic acid (HA) depend on its molecular size. High-molecular weight HA (HMW-HA) is an important component of the endothelial wall and has anti-inflammatory and antioxidant properties. Under inflammation or hypoxia, HMW-HA is degraded by hyaluronidases, such as HYAL-1 resulting in pro-infla...

journal_title：Scientific reports

authors： Meszaros M,Kis A,Kunos L,Tarnoki AD,Tarnoki DL,Lazar Z,Bikov A

更新日期：2020-11-10 00:00:00

abstract：:The study of network topology provides insight into the function and behavior of physical, social, and biological systems. A natural step towards discovering the organizing principles of these complex topologies is to identify a reduced network representation using cohesive subgroups or communities. This procedure oft...

journal_title：Scientific reports

authors： Sinha A,Gleich DF,Ramani K

更新日期：2018-08-09 00:00:00

abstract：:One of the challenges of implementing free-space quantum key distribution (QKD) systems working in daylight is to remove unwanted background noise photons from sunlight. Elaborate elimination of background photons in the spectral, temporal, and spatial domains is an indispensable requirement to decrease the quantum bi...

journal_title：Scientific reports

authors： Ko H,Kim KJ,Choe JS,Choi BS,Kim JH,Baek Y,Youn CJ

更新日期：2018-10-17 00:00:00

abstract：:Mitochondrial genomes exhibit diverse features among eukaryotes in the aspect of gene content, genome structure, and the mobile genetic elements such as introns and plasmids. Although the number of published mitochondrial genomes is increasing at tremendous speed, those of several lineages remain unexplored. Here, we ...

journal_title：Scientific reports

authors： Nishimura Y,Shiratori T,Ishida KI,Hashimoto T,Ohkuma M,Inagaki Y

更新日期：2019-03-19 00:00:00

abstract：:Cardiomyocytes differentiated from human pluripotent stem cells provide promising tools for screening of cardiotoxic drugs. For evaluation of human pluripotent stem cell-derived cardiomyocytes for cardiotoxicity test, in the present study, human embryonic stem cells (hESCs) were differentiated to cardiomyocytes, follo...

journal_title：Scientific reports

authors： Kim HS,Yoon JW,Li H,Jeong GO,Park JJ,Shin SE,Jang IH,Kim JH,Park WS

更新日期：2017-10-23 00:00:00

abstract：:Human milk delivers an array of bioactive components that safeguard infant growth and development and maintain healthy gut microbiota. Milk fat globule membrane (MFGM) is a biologically functional fraction of milk increasingly linked to beneficial outcomes in infants through protection from pathogens, modulation of th...

journal_title：Scientific reports

authors： He X,Parenti M,Grip T,Lönnerdal B,Timby N,Domellöf M,Hernell O,Slupsky CM

更新日期：2019-08-12 00:00:00

abstract：:Tumor progression, limited efficacy of current standard treatments, and the rise in patient mortality are associated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1α activation. For this reason, recent investigations have focused on HIF-targeting therapeutic agents, with encoura...

journal_title：Scientific reports

authors： Mangraviti A,Raghavan T,Volpin F,Skuli N,Gullotti D,Zhou J,Asnaghi L,Sankey E,Liu A,Wang Y,Lee DH,Gorelick N,Serra R,Peters M,Schriefer D,Delaspre F,Rodriguez FJ,Eberhart CG,Brem H,Olivi A,Tyler B

更新日期：2017-11-02 00:00:00

abstract：:Despite the unique nature of endemic species, their origin and population history remain poorly studied. We investigated the population history of 28 coral reef fish species, close related, from the Gambier and Marquesas Islands, from five families, with range size varying from widespread to small-range endemic. We an...

journal_title：Scientific reports

authors： Delrieu-Trottin E,Mona S,Maynard J,Neglia V,Veuille M,Planes S

更新日期：2017-01-16 00:00:00