Adipose tissue in health and disease through the lens of its building blocks.

abstract：:Bisphenol A (BPA) and silybin are considered xenoestrogens and could interfere with the action of endogenous hormones. It was demonstrated a higher level of BPA in plasma of nonalcoholic steatohepatitis (NASH) patients, compared to those with steatosis (NAFL). We investigated the effect of BPA and silybin, alone or in...

journal_title：Scientific reports

authors： Lama S,Vanacore D,Diano N,Nicolucci C,Errico S,Dallio M,Federico A,Loguercio C,Stiuso P

更新日期：2019-03-01 00:00:00

abstract：:Previous research has shown that low-level visual features (i.e., low-level visual saliency) as well as socially relevant information predict gaze allocation in free viewing conditions. However, these studies mainly used static and highly controlled stimulus material, thus revealing little about the robustness of atte...

journal_title：Scientific reports

authors： Rubo M,Gamer M

更新日期：2018-02-28 00:00:00

abstract：:The sensitivity and accuracy of the Risk/Injury/Failure/Loss/End-stage (RIFLE) versus acute kidney injury Network (AKIN) criteria for acute kidney injury (AKI) in critically ill patients remains uncertain. Therefore, we performed a systematic review and meta-analysis to investigate the incidence and prognostic value o...

journal_title：Scientific reports

authors： Xiong J,Tang X,Hu Z,Nie L,Wang Y,Zhao J

更新日期：2015-12-07 00:00:00

abstract：:We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21)  W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...

journal_title：Scientific reports

authors： Faenov AY,Colgan J,Hansen SB,Zhidkov A,Pikuz TA,Nishiuchi M,Pikuz SA,Skobelev IY,Abdallah J,Sakaki H,Sagisaka A,Pirozhkov AS,Ogura K,Fukuda Y,Kanasaki M,Hasegawa N,Nishikino M,Kando M,Watanabe Y,Kawachi T,Masuda S

更新日期：2015-09-02 00:00:00

abstract：:A global insight into the roles of multiple P-type calcium ATPase (CA) pumps in sustaining the life of a filamentous fungal pathogen is lacking. Here we elucidated the functions of five CA pumps (Eca1, Spf1 and PmcA/B/C) following previous characterization of Pmr1 in Beauveria bassiana, a fungal insect pathogen. The f...

journal_title：Scientific reports

authors： Wang J,Zhu XG,Ying SH,Feng MG

更新日期：2017-05-03 00:00:00

abstract：:Tomato spotted wilt virus is a wide-spread plant disease in the world. It can threaten thousands of plants with a persistent and propagative manner. Early disease detection is expected to be able to control the disease spread, to facilitate management practice, and further to guarantee accompanying economic benefits. ...

journal_title：Scientific reports

authors： Wang D,Vinson R,Holmes M,Seibel G,Bechar A,Nof S,Tao Y

更新日期：2019-03-13 00:00:00

abstract：:Pilonidal sinus disease (PSD) is increasing globally. A recent meta-analysis and merged-data analysis showed that recurrence rates in PSD depend essentially on follow-up time and specific surgical procedures. However, the global distribution of surgical approaches and respective recurrence rates have never been studie...

journal_title：Scientific reports

authors： Doll D,Orlik A,Maier K,Kauf P,Schmid M,Diekmann M,Vogt AP,Stauffer VK,Luedi MM

更新日期：2019-10-22 00:00:00

abstract：:The thermal field theory is applied to fermionic superfluids by doubling the degrees of freedom of the BCS theory. We construct the two-mode states and the corresponding Bogoliubov transformation to obtain the BCS thermal vacuum. The expectation values with respect to the BCS thermal vacuum produce the statistical ave...

journal_title：Scientific reports

authors： Hou XY,Huang Z,Guo H,He Y,Chien CC

更新日期：2018-08-10 00:00:00

abstract：:Oryza coarctata (KKLL; 2n = 4x = 48, 665 Mb) also known as Porteresia coarctata is an extreme halophyte species of genus Oryza. Using Illumina and Nanopore reads, we achieved the assembled genome size of 569.9 Mb, accounting 85.69% of the estimated genome size with N50 of 1.85 Mb and 19.89% repetitive region. We also ...

journal_title：Scientific reports

authors： Mondal TK,Rawal HC,Chowrasia S,Varshney D,Panda AK,Mazumdar A,Kaur H,Gaikwad K,Sharma TR,Singh NK

更新日期：2018-09-12 00:00:00

abstract：:Efficient hematopoietic reconstitution of wild type mice requires preconditioning. Established experimental protocols exist to transplant hematopoietic stem cells into lethally irradiated or chemically myeloablated adult mice or unirradiated immunodeficient mice. We sought to develop a protocol to reconstitute immuno-...

journal_title：Scientific reports

authors： Laky K,Dugan P,Frischmeyer-Guerrerio PA

更新日期：2018-08-16 00:00:00

abstract：:Leaching of nitrate from fertilisers diminishes nitrogen use efficiency (the portion of nitrogen used by a plant) and is a major source of agricultural pollution. To improve nitrogen capture, grasses such as brachiaria are increasingly used, especially in South America and Africa, as a cover crop, either via intercrop...

journal_title：Scientific reports

authors： Galdos MV,Brown E,Rosolem CA,Pires LF,Hallett PD,Mooney SJ

更新日期：2020-03-19 00:00:00

abstract：:The Next-Generation Sequencing (NGS) platforms provide a major approach to obtaining millions of short reads from samples. NGS has been used in a wide range of analyses, such as for determining genome sequences, analyzing evolutionary processes, identifying gene expression and resolving metagenomic analyses. Usually, ...

journal_title：Scientific reports

authors： Gaia ASC,de Sá PHCG,de Oliveira MS,Veras AAO

更新日期：2019-08-12 00:00:00

abstract：:We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA methylation landsca...

journal_title：Scientific reports

authors： Massart R,Dymov S,Millecamps M,Suderman M,Gregoire S,Koenigs K,Alvarado S,Tajerian M,Stone LS,Szyf M

更新日期：2016-01-28 00:00:00

abstract：:By combining the two basic deformation mechanisms for auxetic open-cell metamaterials, re-entrant angle and chirality, new hybrid chiral mechanical metamaterials are designed and fabricated via a multi-material 3D printer. Results from mechanical experiments on the 3D printed prototypes and systematic Finite Element (...

journal_title：Scientific reports

authors： Jiang Y,Li Y

更新日期：2018-02-05 00:00:00

abstract：:Although the cause of Alzheimer's disease (AD) is unknown, glial-induced neuroinflammation is an early symptom. Familial AD is caused by increases in amyloid-beta (Aβ) peptide, particularly soluble oligomeric (oAβ), considered a proximal neurotoxin and neuroinflammatory stimuli. APOE4, a naturally occurring genotype o...

journal_title：Scientific reports

authors： Ghura S,Tai L,Zhao M,Collins N,Che CT,Warpeha KM,LaDu MJ

更新日期：2016-07-07 00:00:00

abstract：:Hirsutella sinensis mycelium (HSM), the anamorph of Cordyceps sinensis, is a traditional Chinese medicine that has been shown to possess various pharmacological properties. We previously reported that this fungus suppresses interleukin-1β and IL-18 secretion by inhibiting both canonical and non-canonical inflammasomes...

journal_title：Scientific reports

authors： Huang TT,Lai HC,Ko YF,Ojcius DM,Lan YW,Martel J,Young JD,Chong KY

更新日期：2015-10-26 00:00:00

abstract：:We hypothesized that beyond the Thalassophryne nattereri venoms ability to induce in mice a strong specific-Th2 response with high levels of specific IgE/IgG1, it would be able to trigger anaphylaxis in sensitized individuals. To investigate whether the venom is capable of inducing an allergic reaction in mice and cha...

journal_title：Scientific reports

authors： Bruni FM,Coutinho EMM,Andrade-Barros AI,Grund LZ,Lopes-Ferreira M,Lima C

更新日期：2020-01-17 00:00:00

abstract：:We describe a multiplexed RNA aptamer selection to 19 different targets simultaneously using a microcolumn-based device, MEDUSA (Microplate-based Enrichment Device Used for the Selection of Aptamers), as well as a modified selection process, that significantly reduce the time and reagents needed for selections. We exp...

journal_title：Scientific reports

authors： Reinholt SJ,Ozer A,Lis JT,Craighead HG

更新日期：2016-07-19 00:00:00

abstract：:Riverine and atmospheric inputs are often considered as the main terrestrial sources of dissolved inorganic nitrogen (DIN), phosphorus (DIP), and silicon (DSi) in the ocean. However, the fluxes of nutrients via submarine groundwater discharge (SGD) often exceed riverine inputs in different local and regional scale set...

journal_title：Scientific reports

authors： Cho HM,Kim G,Kwon EY,Moosdorf N,Garcia-Orellana J,Santos IR

更新日期：2018-02-05 00:00:00

abstract：:Although 70-80% of newly diagnosed ovarian cancer patients respond to first-line therapy, almost all relapse and five-year survival remains below 50%. One strategy to increase five-year survival is prolonging time to relapse by improving first-line therapy response. However, no biomarker today can accurately predict i...

journal_title：Scientific reports

authors： Shuford S,Wilhelm C,Rayner M,Elrod A,Millard M,Mattingly C,Lotstein A,Smith AM,Guo QJ,O'Donnell L,Elder J,Puls L,Weroha SJ,Hou X,Zanfagnin V,Nick A,Stany MP,Maxwell GL,Conrads T,Sood AK,Orr D,Holmes LM,Gevaert

更新日期：2019-08-01 00:00:00

abstract：:A previous study identified 3 nonsynonymous and 6 synonymous mutations in the entire mosquito sodium channel of Culex quinquefasciatus, the prevalence of which were strongly correlated with levels of resistance and increased dramatically following insecticide selection. However, it is unclear whether this is unique to...

journal_title：Scientific reports

authors： Li T,Zhang L,Reid WR,Xu Q,Dong K,Liu N

更新日期：2012-01-01 00:00:00

abstract：:Bast fibres are long extraxylary cells which mechanically support the phloem and they are divided into xylan- and gelatinous-type, depending on the composition of their secondary cell walls. The former, typical of jute/kenaf bast fibres, are characterized by the presence of xylan and a high degree of lignification, wh...

journal_title：Scientific reports

authors： Guerriero G,Behr M,Legay S,Mangeot-Peter L,Zorzan S,Ghoniem M,Hausman JF

更新日期：2017-07-10 00:00:00

abstract：:Zebrafish embryos are translucent and develop rapidly in individual eggs ex utero; they are widely used as models for embryogenesis and organ development for human diseases and drug discovery. Lysine crotonylation (Kcr) is a type of histone post-translational modifications discovered in 2011. Kcr dynamics are involved...

journal_title：Scientific reports

authors： Kwon OK,Kim SJ,Lee S

更新日期：2018-02-26 00:00:00

abstract：:At the moment it is unknown to what extent the impaired function of T lymphocytes in ESRD patients depends on uremia, and to what extent on hemodialysis (HD) procedure. Therefore, the purpose of the study was to evaluate percentages of T lymphocyte subpopulations ex vivo, plasma concentrations of IL12p70, TNF, IL-10, ...

journal_title：Scientific reports

authors： Lisowska KA,Pindel M,Pietruczuk K,Kuźmiuk-Glembin I,Storoniak H,Dębska-Ślizień A,Witkowski JM

更新日期：2019-03-25 00:00:00

abstract：:Genes central to drug absorption, distribution, metabolism and elimination (ADME) also regulate numerous endogenous molecules. The Remote Sensing and Signaling Hypothesis argues that an ADME gene-centered network-including SLC and ABC "drug" transporters, "drug" metabolizing enzymes (DMEs), and regulatory genes-is ess...

journal_title：Scientific reports

authors： Rosenthal SB,Bush KT,Nigam SK

更新日期：2019-08-15 00:00:00

abstract：:We analyze a transition from single peaked to bimodal velocity distribution in a relativistic fluid under increasing temperature, in contrast with a non-relativistic gas, where only a monotonic broadening of the bell-shaped distribution is observed. Such transition results from the interplay between the raise in therm...

journal_title：Scientific reports

authors： Mendoza M,Araújo NA,Succi S,Herrmann HJ

更新日期：2012-01-01 00:00:00

abstract：:Previous studies demonstrated distinct neural correlates underpinning impaired self-regulation (dysregulation) between individuals with autism spectrum disorder (ASD) and typically developing controls (TDC). However, the impacts of dysregulation on white matter (WM) microstructural property in ASD and TDC remain uncle...

journal_title：Scientific reports

authors： Ni HC,Lin HY,Tseng WI,Gau SS

更新日期：2020-08-14 00:00:00

abstract：:The mechanisms contributing to collective attention in humans remain unclear. Research indicates that pedestrians utilise the gaze direction of others nearby to acquire environmentally relevant information, but it is not known which, if any, additional social cues influence this transmission. Extending upon previous f...

journal_title：Scientific reports

authors： Gallup AC,Chong A,Kacelnik A,Krebs JR,Couzin ID

更新日期：2014-07-23 00:00:00

abstract：:The aim of the present study was to evaluate sleep and mood disorders in patients with irritating ocular diseases. The study design was a cross-sectional/case-control study conducted in six eye clinics. Out of 715 outpatients diagnosed with irritating ocular surface diseases and initially enrolled, 301 patients with d...

journal_title：Scientific reports

authors： Ayaki M,Kawashima M,Negishi K,Kishimoto T,Mimura M,Tsubota K

更新日期：2016-03-01 00:00:00

abstract：:Mitochondrial genomes exhibit diverse features among eukaryotes in the aspect of gene content, genome structure, and the mobile genetic elements such as introns and plasmids. Although the number of published mitochondrial genomes is increasing at tremendous speed, those of several lineages remain unexplored. Here, we ...

journal_title：Scientific reports

authors： Nishimura Y,Shiratori T,Ishida KI,Hashimoto T,Ohkuma M,Inagaki Y

更新日期：2019-03-19 00:00:00