Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging.

abstract：:Transgenic rice producing insecticidal proteins from Bacillus thuringiensis (Bt) could help protect the plants from damage by lepidopteran pests. However, one concern is the potential of Bt rice to harm non-target natural enemies, which play a vital role in pest control. In the present study, the potential effects of ...

journal_title：Scientific reports

authors： Tian JC,Romeis J,Liu K,Zhang FC,Zheng XS,Xu HX,Chen GH,He XC,Lu ZX

更新日期：2017-08-10 00:00:00

abstract：:The tricarboxylic acid cycle produces NADH for oxidative phosphorylation and fumarase [EC 4.2.1.2] is a critical enzyme in this cycle, catalysing the reversible conversion of fumarate and L-malate. Fumarase is applied to industrial L-malate production as a biocatalyst. L-malate is used in a wide range of industries su...

journal_title：Scientific reports

authors： Katayama N,Takeya M,Osanai T

更新日期：2019-07-23 00:00:00

abstract：:The mangrove fern genus Acrostichum grows in the extremely unstable marine intertidal zone under harsh conditions, such as high salt concentrations, tidal rhythms and long-term climate changes. To explore the phylogenetic relationships and molecular mechanisms underlying adaptations in this genus, we sequenced the tra...

journal_title：Scientific reports

authors： Zhang Z,He Z,Xu S,Li X,Guo W,Yang Y,Zhong C,Zhou R,Shi S

更新日期：2016-10-26 00:00:00

abstract：:CSNK2B, which encodes the beta subunit of casein kinase II (CK2), plays an important role in neuron morphology and synaptic transmission. Variants in CSNK2B associated with epilepsy and/or intellectual disability (ID)/developmental delay (DD) have been reported in five cases only. Among the 816 probands suspected here...

journal_title：Scientific reports

authors： Li J,Gao K,Cai S,Liu Y,Wang Y,Huang S,Zha J,Hu W,Yu S,Yang Z,Xie H,Yan H,Wang J,Wu Y,Jiang Y

更新日期：2019-11-29 00:00:00

abstract：:Precise temporal coding is necessary for proper acoustic analysis. However, at cortical level, forward suppression appears to limit the ability of neurons to extract temporal information from natural sound sequences. Here we studied how temporal processing can be maintained in the bats' cortex in the presence of suppr...

journal_title：Scientific reports

authors： Beetz MJ,Hechavarría JC,Kössl M

更新日期：2016-06-30 00:00:00

abstract：:Extensive computational modeling and simulations have been carried out, in the present study, to uncover the fundamental reaction pathway for butyrylcholinesterase (BChE)-catalyzed hydrolysis of ghrelin, demonstrating that the acylation process of BChE-catalyzed hydrolysis of ghrelin follows an unprecedented single-st...

journal_title：Scientific reports

authors： Yao J,Yuan Y,Zheng F,Zhan CG

更新日期：2016-02-29 00:00:00

abstract：:Epigallocatechin-3-gallate (EGCG), a green tea-derived polyphenol, exhibits antitumor activities. An EGCG nanoemulsion (nano-EGCG) was prepared to improve the stability and reduce the side effects of EGCG for treatment of human lung cancer cells, and the antitumor effects were studied. The possible molecular mechanism...

journal_title：Scientific reports

authors： Chen BH,Hsieh CH,Tsai SY,Wang CY,Wang CC

更新日期：2020-03-20 00:00:00

abstract：:The abundance and diversity of bacteria in two types of ponds were investigated by quantitative PCR and Illumina MiSeq sequencing. The results revealed that the abundance of bacterial 16S rRNA genes in D ponds (with grass carp fed sudan grass) was significantly lower than that in E ponds (with grass carp fed commercia...

journal_title：Scientific reports

authors： Qin Y,Hou J,Deng M,Liu Q,Wu C,Ji Y,He X

更新日期：2016-10-19 00:00:00

abstract：:The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation of testis different...

journal_title：Scientific reports

authors： Otake T,Kuroiwa A

更新日期：2016-09-09 00:00:00

abstract：:The anisotropic shape of DNA molecules allows them to form lyotropic liquid crystals (LCs) at high concentrations. This liquid crystalline arrangement is also found in vivo (e.g., in bacteriophage capsids, bacteria or human sperm nuclei). However, the role of DNA liquid crystalline organization in living organisms sti...

journal_title：Scientific reports

authors： Brach K,Hatakeyama A,Nogues C,Olesiak-Banska J,Buckle M,Matczyszyn K

更新日期：2018-03-14 00:00:00

abstract：:The ends of eukaryotic chromosomes are capped by telomeres which consist of tandem G-rich DNA repeats stabilized by the shelterin protein complex. Telomeres shorten progressively in most normal cells due to the end replication problem. In more than 85% of cancers however, the telomere length is maintained by telomeras...

journal_title：Scientific reports

authors： Hwang H,Opresko P,Myong S

更新日期：2014-09-29 00:00:00

abstract：:Located across the equator, the East Africa region is among regions of Africa which have previously known the severe vegetation degradation. Some known reasons are associated with the climate change events and unprofessional agricultural practices. For this purpose, the Advanced Very High Resolution Radiometer (AVHRR)...

journal_title：Scientific reports

authors： Kalisa W,Igbawua T,Henchiri M,Ali S,Zhang S,Bai Y,Zhang J

更新日期：2019-11-14 00:00:00

abstract：:The stochastic tunneling-basin hopping method (STUN-BH) was utilized to obtain the most stable peptide S7 configuration (Ac-Ser-Ser-Phe-Pro-Gln-Pro-Asn-CONH2) adsorbed on Au(111) facet. After the most stable S7 configuration was found, molecular dynamics (MD) simulation was conducted to investigate the thermal stabili...

journal_title：Scientific reports

authors： Lin CH,Ju SP,Su JW,Li DE

更新日期：2020-02-07 00:00:00

abstract：:Leaf flattening influences plant photosynthesis, thereby affecting product yield and quality. Here, we obtained a stably inherited leaf crinkled mutant (lcm), derived from the Chinese cabbage doubled haploid (DH) 'FT' line using EMS mutagenesis combined with isolated microspore culture. The crinkled phenotype was cont...

journal_title：Scientific reports

authors： Zhang M,Huang S,Gao Y,Fu W,Qu G,Zhao Y,Shi F,Liu Z,Feng H

更新日期：2020-08-18 00:00:00

abstract：:Cytolytic score (CYT), calculated from mRNA expression levels of granzyme and perforin, positively correlates with CD8+ T cell infiltration/activity in a variety of cancers. Unlike other cancers, higher CYT has been associated with worse prognosis in glioblastoma (GBM). To address this discrepancy, we sought to invest...

journal_title：Scientific reports

authors： Haddad AF,Chen JS,Oh T,Pereira MP,Joshi RS,Aghi MK

更新日期：2020-10-16 00:00:00

abstract：:Tin selenide has attracted much research interest due to its unprecedentedly high thermoelectric figure of merit (ZT). For real applications, it is desirable to increase the ZT value in the lower-temperature range, as the peak ZT value currently exists near the melting point. It is shown in this paper that the structu...

journal_title：Scientific reports

authors： Yu H,Dai S,Chen Y

更新日期：2016-05-19 00:00:00

abstract：:An appropriate tillage method must be implemented by maize growers to improve phosphorus dynamics in the soil in order to increase phosphorus uptake by plant. The objective of this study was to investigate the effects of tillage systems on phosphorus and its fractions in rhizosphere and non-rhizosphere soils under mai...

journal_title：Scientific reports

authors： Xomphoutheb T,Jiao S,Guo X,Mabagala FS,Sui B,Wang H,Zhao L,Zhao X

更新日期：2020-04-20 00:00:00

abstract：:We compared the gut microbial populations in 100 women, from rural Ghana and urban US [50% lean (BMI < 25 kg/m2) and 50% obese (BMI ≥ 30 kg/m2)] to examine the ecological co-occurrence network topology of the gut microbiota as well as the relationship of short chain fatty acids (SCFAs) with obesity. Ghanaians consumed...

journal_title：Scientific reports

authors： Dugas LR,Bernabé BP,Priyadarshini M,Fei N,Park SJ,Brown L,Plange-Rhule J,Nelson D,Toh EC,Gao X,Dong Q,Sun J,Kliethermes S,Gottel N,Luke A,Gilbert JA,Layden BT

更新日期：2018-11-20 00:00:00

abstract：:CoO nanocrystal/graphene nanosheets (GNS) composites, consisting of a triangular CoO nanocrystal of 2~20 nm on the surface of GNS, are synthesized by a mild synthetic method. First, cobalt acetate tetrahydrate is recrystallized in the alcohol solution at a low temperature. Then, graphene oxide mixed with cobalt-precur...

journal_title：Scientific reports

authors： Guan Q,Cheng J,Li X,Wang B,Huang L,Nie F,Ni W

更新日期：2015-05-11 00:00:00

abstract：:This study aimed to examine the effect of transcutaneous electrical nerve stimulation (TENS) on stair climbing capacity in individuals with pre-radiographic to mild knee osteoarthritis (OA). This is a secondary analysis of data from a single, participant-blinded, randomized controlled trial with a pre-post design. Par...

journal_title：Scientific reports

authors： Iijima H,Eguchi R,Shimoura K,Yamada K,Aoyama T,Takahashi M

更新日期：2020-04-29 00:00:00

abstract：:Countries in the Asia Pacific region aim to eliminate malaria by 2030. A cornerstone of malaria elimination is the effective management of Anopheles mosquito vectors. Current control tools such as insecticide treated nets or indoor residual sprays target mosquitoes in human dwellings. We find in a high transmission re...

journal_title：Scientific reports

authors： Waite JL,Swain S,Lynch PA,Sharma SK,Haque MA,Montgomery J,Thomas MB

更新日期：2017-01-16 00:00:00

abstract：:Society's increasing interactions with technology are creating extensive "digital traces" of our collective human behavior. These new data sources are fuelling the rapid development of the new field of computational social science. To investigate user attention to the Hurricane Sandy disaster in 2012, we analyze data ...

journal_title：Scientific reports

authors： Preis T,Moat HS,Bishop SR,Treleaven P,Stanley HE

更新日期：2013-11-05 00:00:00

abstract：:This study aimed to determine the characteristics of CT changes in patients with severe coronavirus disease 2019 (COVID-19) based on prognosis. Serial CT scans in 47 patients with severe COVID-19 were reviewed. The patterns, distribution and CT score of lung abnormalities were assessed. Scans were classified according...

journal_title：Scientific reports

authors： Liang B,Xie L,Yang F,Makamure J,Zhang L,Pang R,Du P,Fan W,Zheng C

更新日期：2020-12-14 00:00:00

abstract：:Patients who undergo orthotopic liver transplantation often sustain acute kidney injury(AKI). The toll-like receptor 4(TLR4)/Nuclear factor-кB(NF-кB) pathway plays a role in AKI. Dexmedetomidine(Dex) has been shown to attenuate AKI. The current study aimed to determine whether liver transplantation-induced AKI is asso...

journal_title：Scientific reports

authors： Yao H,Chi X,Jin Y,Wang Y,Huang P,Wu S,Xia Z,Cai J

更新日期：2015-11-20 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Yang CH,Chuang LY,Lin YD

更新日期：2017-11-23 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) development is a multistage process includes the normal, dysplasia and squamous cell carcinoma (SCC) stages. Recently, increasing evidence has suggested that the tumor microenvironment (TME) is an integral part of malignant transformation. Exploring certain key node genes ...

journal_title：Scientific reports

authors： Wu T,Hong Y,Jia L,Wu J,Xia J,Wang J,Hu Q,Cheng B

更新日期：2016-02-01 00:00:00

abstract：:Harmaline (HAR), a natural occurrence β-carboline alkaloid, was isolated from the seeds of Peganum harmala and exhibited potent antitumor effect. In this study, the anti-gastric tumor effects of HAR were firstly investigated in vitro and in vivo. The results strongly showed that HAR could inhibit tumor cell proliferat...

journal_title：Scientific reports

authors： Wang Y,Wang C,Jiang C,Zeng H,He X

更新日期：2015-12-18 00:00:00

abstract：:We employ nematic liquid crystals as the nonlinear medium to recover noisy images via stochastic resonance, in which nonlinear coupling allows signals to grow at the expense of noise. The process is theoretically analyzed and the cross-correlation is numerically calculated. It is found that the quality of output image...

journal_title：Scientific reports

authors： Feng X,Liu H,Huang N,Wang Z,Zhang Y

更新日期：2019-03-08 00:00:00

abstract：:Recently, the first-order synchronization transition has been studied in systems of coupled phase oscillators. In this paper, we propose a framework to investigate the synchronization in the frequency-weighted Kuramoto model with all-to-all couplings. A rigorous mean-field analysis is implemented to predict the possib...

journal_title：Scientific reports

authors： Xu C,Sun Y,Gao J,Qiu T,Zheng Z,Guan S

更新日期：2016-02-23 00:00:00

abstract：:Engineered Terahertz (THz) metamaterials presented an unique characteristics for biosensing application due to their accurately tunable resonance frequency, which is in accord with vibrational frequency of some important biomolecules such as cancer biomarker. However, water absorption in THz regime is an obstacle to e...

journal_title：Scientific reports

authors： Geng Z,Zhang X,Fan Z,Lv X,Chen H

更新日期：2017-11-27 00:00:00