Temporal tuning in the bat auditory cortex is sharper when studied with natural echolocation sequences.

abstract：:Extracellular vesicles (EVs), including exosomes and microvesicles, are nano-sized membrane vesicles containing proteins and nucleic acids, which act as intercellular messengers. They play an important role in a variety of physiological processes, as well as in pathological situations such as inflammation or cancer. H...

journal_title：Scientific reports

authors： Bonjoch L,Gironella M,Iovanna JL,Closa D

更新日期：2017-06-09 00:00:00

abstract：:An intermediate band in the band gap of semiconductors is fundamental to the development of the intermediate band solar cells, but it is usually produced artificially, which imposes technical challenges on the experimental realization. Here we found that there are natural intermediate bands in the band gaps of the I2-...

journal_title：Scientific reports

authors： Liu Q,Cai Z,Han D,Chen S

更新日期：2018-01-25 00:00:00

abstract：:Biological invasions are a major threat to biodiversity and ecosystem functioning. Successful invasions depend on the interplay of multiple abiotic and biotic factors, however, the process of the invasion itself is often overlooked. The temporal variation of environmental factors suggests that a 'window of opportunity...

journal_title：Scientific reports

authors： Bolius S,Wiedner C,Weithoff G

更新日期：2019-06-05 00:00:00

abstract：:Pancreatic cancer is predominantly lethal, and is primarily treated using gemcitabine, with increasing resistance. Therefore, novel agents that increase tumor sensitivity to gemcitabine are needed. Histone deacetylase (HDAC) inhibitors are emerging therapeutic agents, since HDAC plays an important role in cancer initi...

journal_title：Scientific reports

authors： Lee HS,Park SB,Kim SA,Kwon SK,Cha H,Lee DY,Ro S,Cho JM,Song SY

更新日期：2017-01-30 00:00:00

abstract：:Ecosystem carbon carrying capacity (CCC) is determined by prevailing climate and natural disturbance regimes, conditions that are projected to change significantly. The interaction of changing climate and its effects on disturbance regimes is expected to affect forest regeneration and growth, which may diminish forest...

journal_title：Scientific reports

authors： Liang S,Hurteau MD,Westerling AL

更新日期：2017-05-25 00:00:00

abstract：:A large number of drugs are administered on different mucosal surfaces. However, due to the poor mucoadhesion of the current formulations, their bioavailability is often very low. The development of efficient mucoadhesive drug delivery systems is thus crucial for improving the performance of these drugs. The mucoadhes...

journal_title：Scientific reports

authors： Ouellette M,Masse F,Lefebvre-Demers M,Maestracci Q,Grenier P,Millar R,Bertrand N,Prieto M,Boisselier É

更新日期：2018-09-25 00:00:00

abstract：:Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal weight in Anxa5-null...

journal_title：Scientific reports

authors： Ueki H,Mizushina T,Laoharatchatathanin T,Terashima R,Nishimura Y,Rieanrakwong D,Yonezawa T,Kurusu S,Hasegawa Y,Brachvogel B,Pöschl E,Kawaminami M

更新日期：2012-01-01 00:00:00

abstract：:To investigate the influence of various factors on the two outcome parameters "procedure - specific complication" (femoral head necrosis, infection, nonunion, femoral neck shortening, screw loosening, implant penetration) and "functional outcome" in patients with displaced and undisplaced femoral neck fracture treated...

journal_title：Scientific reports

authors： Ramadanov N,Toma I,Herkner H,Klein R,Behringer W,Matthes G

更新日期：2020-01-20 00:00:00

abstract：:Graphene oxide is being used in energy, optical, electronic and sensor devices due to its unique properties. However, unlike its counterpart - graphene - the thermal transport properties of graphene oxide remain unknown. In this work, we use large-scale molecular dynamics simulations with reactive potentials to system...

journal_title：Scientific reports

authors： Mu X,Wu X,Zhang T,Go DB,Luo T

更新日期：2014-01-28 00:00:00

abstract：:The 37 currently recognized Bemisia tabaci cryptic species are economically important species and contain both primary and secondary endosymbionts, but their diversity has never been mapped systematically across the group. To achieve this, PacBio sequencing of full-length bacterial 16S rRNA gene amplicons was carried ...

journal_title：Scientific reports

authors： Wang HL,Lei T,Xia WQ,Cameron SL,Liu YQ,Zhang Z,Gowda MMN,De Barro P,Navas-Castillo J,Omongo CA,Delatte H,Lee KY,Patel MV,Krause-Sakate R,Ng J,Wu SL,Fiallo-Olivé E,Liu SS,Colvin J,Wang XW

更新日期：2019-04-25 00:00:00

abstract：:A relation exists between network proximity of molecular entities in interaction networks, functional similarity and association with diseases. The identification of network regions associated with biological functions and pathologies is a major goal in systems biology. We describe a network diffusion-based pipeline f...

journal_title：Scientific reports

authors： Bersanelli M,Mosca E,Remondini D,Castellani G,Milanesi L

更新日期：2016-10-12 00:00:00

abstract：:Inference of the biological roles of lncRNAs in breast cancer development remains a challenge. Here, we analyzed RNA-seq data in tumor and normal breast tissue samples from 18 breast cancer patients and 18 healthy controls and constructed a functional lncRNA-mRNA co-expression network. We revealed two distinctive co-e...

journal_title：Scientific reports

authors： Wu W,Wagner EK,Hao Y,Rao X,Dai H,Han J,Chen J,Storniolo AMV,Liu Y,He C

更新日期：2016-09-06 00:00:00

abstract：:Time-series data from multicomponent systems capture the dynamics of the ongoing processes and reflect the interactions between the components. The progression of processes in such systems usually involves check-points and events at which the relationships between the components are altered in response to stimuli. Det...

journal_title：Scientific reports

authors： Omranian N,Mueller-Roeber B,Nikoloski Z

更新日期：2015-03-11 00:00:00

abstract：:A lack of information regarding whether genetic polymorphisms of SLCO1B1 and ABCG2 affect the pharmacokinetics (PKs)/pharmacodynamics (PDs) of rosuvastatin in elderly subjects prevents optimal individualized pharmacotherapy of rosuvastatin in clinical settings. This study aimed to investigate the effect of age and gen...

journal_title：Scientific reports

authors： Kim Y,Yoon S,Choi Y,Yoon SH,Cho JY,Jang IJ,Yu KS,Chung JY

更新日期：2019-12-19 00:00:00

abstract：:This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β2-adrenergic receptor (β2-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficient for its interaction ...

journal_title：Scientific reports

authors： Sencanski M,Glisic S,Šnajder M,Veljkovic N,Poklar Ulrih N,Mavri J,Vrecl M

更新日期：2019-11-12 00:00:00

abstract：:Magnetic resonance imaging (MRI) has evolved into an outstandingly versatile diagnostic modality, as it has the ability to non-invasively produce detailed information on a tissue's structure and function. Complementary data is normally obtained in separate measurements, either as contrast-weighted images, which are fa...

journal_title：Scientific reports

authors： Gómez PA,Molina-Romero M,Buonincontri G,Menzel MI,Menze BH

更新日期：2019-06-11 00:00:00

abstract：:Prenylated indole diketopiperazine (DKP) alkaloids are important bioactive molecules or their precursors. In the context of synthetic biology, efficient means for their biological production would increase their chemical diversification and the discovery of novel bioactive compounds. Here, we prove the suitability of ...

journal_title：Scientific reports

authors： Dubois P,Correia I,Le Chevalier F,Dubois S,Jacques I,Canu N,Moutiez M,Thai R,Gondry M,Lequin O,Belin P

更新日期：2019-06-25 00:00:00

abstract：:A five-year swine manure application trial and a study of nitrate leaching losses have been conducted. There were three treatments: traditional without manure (CK), traditional matched manure 4500 kg ha-2 (T1) and traditional matched manure 9000 kg ha-2 (T2). Nitrate nitrogen leaching losses at the 30-, 60-, and 90-cm...

journal_title：Scientific reports

authors： Yang S,Wang Y,Liu R,Zhang A,Yang Z

更新日期：2017-10-20 00:00:00

abstract：:We study the impact of light on the mammalian circadian system using the theory of phase response curves. Using a recently developed ansatz we derive a low-dimensional macroscopic model for the core circadian clock in mammals. Significantly, the variables and parameters in our model have physiological interpretations ...

journal_title：Scientific reports

authors： Hannay KM,Forger DB,Booth V

更新日期：2020-11-11 00:00:00

abstract：:Chromosome segment substitution lines (CSSLs) are useful tools for precise mapping of quantitative trait loci (QTLs) and the evaluation of gene action and interaction in inter-specific crosses. In this study, a set of 90 back cross lines at BC2F8 generation derived from Swarna x Oryza nivara IRGC81832 was evaluated fo...

journal_title：Scientific reports

authors： Balakrishnan D,Surapaneni M,Yadavalli VR,Addanki KR,Mesapogu S,Beerelli K,Neelamraju S

更新日期：2020-05-08 00:00:00

abstract：:Chemical reagents used in traditional mineral processing can be toxic and hazardous for the environment. Therefore, the use of biotechnological methods is becoming increasingly important. Great hopes are being placed in the use of microorganisms for bio-beneficiation of raw materials. However, assessment of adhesion a...

journal_title：Scientific reports

authors： Rabia H,Ould Hamou M,Kasperkiewicz K,Brożek J,Augustyniak M

更新日期：2019-09-10 00:00:00

abstract：:We have quantitatively evaluated the macular and peripapillary microvascular changes in eyes with chiasmal compression caused by brain tumors compared with healthy control eyes using optical coherence tomography angiography (OCT-A) and correlated them with other ocular parameters. This cross-sectional study involved t...

journal_title：Scientific reports

authors： Lee GI,Park KA,Oh SY,Kong DS

更新日期：2020-02-07 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Cazanave S,Podtelezhnikov A,Jensen K,Seneshaw M,Kumar DP,Min HK,Santhekadur PK,Banini B,Mauro AG,Oseini AM,Vincent R,Tanis KQ,Webber AL,Wang L,Bedossa P,Mirshahi F,Sanyal AJ

更新日期：2020-05-15 00:00:00

abstract：:Magnesium has been shown to effectively prevent vascular calcification associated with chronic kidney disease. Magnesium has been hypothesized to prevent the upregulation of osteoblastic genes that potentially drives calcification. However, extracellular effects of magnesium on hydroxyapatite formation are largely neg...

journal_title：Scientific reports

authors： Ter Braake AD,Tinnemans PT,Shanahan CM,Hoenderop JGJ,de Baaij JHF

更新日期：2018-02-01 00:00:00

abstract：:The chemiresistive thin film gas sensors with fast response, high sensitivity, low power consumption and mass-produced potency, have been expected for practical application. It requires both sensitive materials, especially exquisite nanomaterials, and efficient substrate chip for heating and electrical addressing. How...

journal_title：Scientific reports

authors： Dai Z,Xu L,Duan G,Li T,Zhang H,Li Y,Wang Y,Wang Y,Cai W

更新日期：2013-01-01 00:00:00

abstract：:The esophageal gland duct may serve as a pathway for the spread of early esophageal squamous cell neoplasia (ESCN) to a deeper layer. Deep intraductal tumor spreading cannot be completely eradicated by ablation therapy. However, the risk factors of ductal involvement (DI) in patients with ESCNs have yet to be investig...

journal_title：Scientific reports

authors： Wang WL,Chang IW,Hsu MH,Chen TH,Tseng CM,Tseng CH,Tai CM,Wang HP,Lee CT

更新日期：2020-04-22 00:00:00

abstract：:Spirometry is required to confirm a chronic obstructive pulmonary disease (COPD) diagnosis, but it is difficult to perform in resource-limited settings. This study aimed to evaluate symptom-based questions for screening of individuals with COPD among Chinese populations. We recruited 3969 adult subjects from the First...

journal_title：Scientific reports

authors： Zhang Q,Wang M,Li X,Wang H,Wang J

更新日期：2016-07-26 00:00:00

abstract：:The domain wall-related change in the anisotropic magnetoresistance in L-shaped permalloy nanowires is measured as a function of the magnitude and orientation of the applied magnetic field. The magnetoresistance curves, compiled into so-called domain wall magnetoresistance state space maps, are used to identify highly...

journal_title：Scientific reports

authors： Corte-León H,Nabaei V,Manzin A,Fletcher J,Krzysteczko P,Schumacher HW,Kazakova O

更新日期：2014-08-13 00:00:00

abstract：:Soil microbial communities directly affect soil functionality through their roles in the cycling of soil nutrients and carbon storage. Microbial communities vary substantially in space and time, between soil types and under different land management. The mechanisms that control the spatial distributions of soil microb...

journal_title：Scientific reports

authors： Xue PP,Carrillo Y,Pino V,Minasny B,McBratney AB

更新日期：2018-08-06 00:00:00

abstract：:Breast tissue heterogeneity is related to risk factors that lead to more aggressive tumour growth and worse prognosis, yet such heterogeneity has not been well characterized. The aim of this study is to reveal the heterogeneous signal patterns of the apparent diffusion coefficient (ADC) of a tumour and its surrounding...

journal_title：Scientific reports

authors： Fan M,He T,Zhang P,Zhang J,Li L

更新日期：2017-06-06 00:00:00