Mammalian Solute Carrier (SLC)-like transporters of Legionella pneumophila.

abstract：:Shikimate is a key intermediate in the synthesis of neuraminidase inhibitors. Compared with traditional methods, microbial production of shikimate has the advantages of environmental friendliness, low cost, feed stock renewability, and product selectivity and diversity. Despite these advantages, shikimate kinase I and...

journal_title：Scientific reports

authors： Gu P,Su T,Wang Q,Liang Q,Qi Q

更新日期：2016-07-13 00:00:00

abstract：:Electroencephalographic hyperscanning was used to investigate interbrain synchronization patterns in dyads of participants interacting through speech. Results show that brain oscillations are synchronized between listener and speaker during oral narratives. This interpersonal synchronization is mediated in part by a l...

journal_title：Scientific reports

authors： Pérez A,Carreiras M,Duñabeitia JA

更新日期：2017-06-23 00:00:00

abstract：:Despite the detailed characterization of the inflammatory and endothelial changes observed in Sickle Cell Disease (SCD), the hierarchical relationship between elements involved in the pathogenesis of this complex disease is yet to be described. Meta-analyses of gene expression studies from public repositories represen...

journal_title：Scientific reports

authors： Hounkpe BW,Fiusa MM,Colella MP,da Costa LN,Benatti Rde O,Saad ST,Costa FF,dos Santos MN,De Paula EV

更新日期：2015-12-09 00:00:00

abstract：:Few-layer black phosphorus (BP) is the most promising material among the two-dimensional materials due to its layered structure and the excellent semiconductor properties. Currently, thin BP atomic layers are obtained mostly by mechanical exfoliation of bulk BP, which limits applications in thin-film based electronics...

journal_title：Scientific reports

authors： Seo S,Lee HU,Lee SC,Kim Y,Kim H,Bang J,Won J,Kim Y,Park B,Lee J

更新日期：2016-03-30 00:00:00

abstract：:Bovine TB (bTB) is endemic in Irish cattle and has eluded eradication despite considerable expenditure, amid debate over the relative roles of badgers and cattle in disease transmission. Using a comprehensive dataset from Northern Ireland (>10,000 km(2); 29,513 cattle herds), we investigated interactions between host ...

journal_title：Scientific reports

authors： Wright DM,Reid N,Ian Montgomery W,Allen AR,Skuce RA,Kao RR

更新日期：2015-08-17 00:00:00

abstract：:We presented the unusual result of photobleaching (PB) in Ge-deficient Ge16.8Se83.2 thin films with continuous irradiation with 560 nm laser for 12000 s, which is contradicted with the previous reports that the PB only occurs in GexSe100-x films with x > 30. Observation of the dynamics variations of the photo-induced ...

journal_title：Scientific reports

authors： Zhang S,Chen Y,Wang R,Shen X,Dai S

更新日期：2017-11-06 00:00:00

abstract：:A tunable high-order sideband spectra generation scheme is presented by using a photonic molecule optomechanical system coupled to a waveguide beyond the perturbation regime. The system is coherently driven by a two-tone laser consisting of a continuous-wave control field and a pulsed driving field which propagates th...

journal_title：Scientific reports

authors： Cao C,Mi SC,Gao YP,He LY,Yang D,Wang TJ,Zhang R,Wang C

更新日期：2016-03-10 00:00:00

abstract：:Basal-like breast cancer (BLBC) is associated with a poor clinical outcome due to the few treatment options and absence of effective targeted agents. Here, we show that malic enzyme 1 (ME1) is dramatically upregulated in BLBC due to ME1 copy number amplification. ME1 expression increases glucose uptake and lactate pro...

journal_title：Scientific reports

authors： Liao R,Ren G,Liu H,Chen X,Cao Q,Wu X,Li J,Dong C

更新日期：2018-11-13 00:00:00

abstract：:It was previously demonstrated that microRNA-199a (miR-199a) was down-regulated in testicular germ cell tumor (TGCT) partially caused by hypermethylation of its promoter. miR-199a is encoded by two loci in the human genome, miR-199a-1 on chromosome (Chr) 19 and miR-199a-2 on Chr 1. Both loci encode the same miR-199a. ...

journal_title：Scientific reports

authors： Chen BF,Suen YK,Gu S,Li L,Chan WY

更新日期：2014-09-18 00:00:00

abstract：:Work stress is a risk factor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile of individuals with work stress. To address this limitation, we conducted a cross-sectional study including 43,593 working adults from a French population-based sample aged 18-72 years (the CONSTA...

journal_title：Scientific reports

authors： Magnusson Hanson LL,Westerlund H,Goldberg M,Zins M,Vahtera J,Hulvej Rod N,Stenholm S,Steptoe A,Kivimäki M

更新日期：2017-08-24 00:00:00

abstract：:Family studies have identified a heritable component to self-harm that is partially independent from comorbid psychiatric disorders. However, the genetic aetiology of broad sense (non-suicidal and suicidal) self-harm has not been characterised on the molecular level. In addition, controversy exists about the degree to...

journal_title：Scientific reports

authors： Campos AI,Verweij KJH,Statham DJ,Madden PAF,Maciejewski DF,Davis KAS,John A,Hotopf M,Heath AC,Martin NG,Rentería ME

更新日期：2020-06-16 00:00:00

abstract：:In recent years, microbial cholesterol oxidases have gained great attention due to its widespread use in medical applications for serum cholesterol determination. Streptomyces aegyptia strain NEAE-102 exhibited high level of extracellular cholesterol oxidase production using a minimum medium containing cholesterol as ...

journal_title：Scientific reports

authors： El-Naggar NE,Soliman HM,El-Shweihy NM

更新日期：2018-02-09 00:00:00

abstract：:The total spatial coverage of Marine Protected Areas (MPAs) within the Brazilian Economic Exclusive Zone (EEZ) has recently achieved the quantitative requirement of the Aichii Biodiversity Target 11. However, the distribution of MPAs in the Brazilian EEZ is still unbalanced regarding the proportion of protected ecosys...

journal_title：Scientific reports

authors： Endo CAK,Gherardi DFM,Pezzi LP,Lima LN

更新日期：2019-06-14 00:00:00

abstract：:Here we present the first report of a carbon-γ-Fe₂O₃ nanoparticle composite of mesoporous carbon, bearing COOH- and phenolic OH- functional groups on its surface, a remarkable and magnetically separable adsorbent, for the radioactive material emitted by the Fukushima Daiichi nuclear power plant accident. Contaminated ...

journal_title：Scientific reports

authors： Yamaguchi D,Furukawa K,Takasuga M,Watanabe K

更新日期：2014-08-13 00:00:00

abstract：:Plant litter represents a major basal resource in streams, where its decomposition is partly regulated by litter traits. Litter-trait variation may determine the latitudinal gradient in decomposition in streams, which is mainly microbial in the tropics and detritivore-mediated at high latitudes. However, this hypothes...

journal_title：Scientific reports

authors： Boyero L,Graça MAS,Tonin AM,Pérez J,J Swafford A,Ferreira V,Landeira-Dabarca A,A Alexandrou M,Gessner MO,McKie BG,Albariño RJ,Barmuta LA,Callisto M,Chará J,Chauvet E,Colón-Gaud C,Dudgeon D,Encalada AC,Figueroa R,Fle

更新日期：2017-09-05 00:00:00

abstract：:Multiple parasitic arthropods of medical importance depend on symbiotic bacteria. While the link between scabies and secondary bacterial infections causing post infective complications of Group A streptococcal and staphylococcal pyoderma is increasingly recognized, very little is known about the microbiota of Sarcopte...

journal_title：Scientific reports

authors： Swe PM,Zakrzewski M,Waddell R,Sriprakash KS,Fischer K

更新日期：2019-08-13 00:00:00

abstract：:Successful immunity requires that a limited pool of αβ T-cell receptors (TCRs) provide cover for a vast number of potential foreign peptide antigens presented by 'self' major histocompatibility complex (pMHC) molecules. Structures of unligated and ligated MHC class-I-restricted TCRs with different ligands, supplemente...

journal_title：Scientific reports

authors： Holland CJ,Rizkallah PJ,Vollers S,Calvo-Calle JM,Madura F,Fuller A,Sewell AK,Stern LJ,Godkin A,Cole DK

更新日期：2012-01-01 00:00:00

abstract：:Sugarcane (Saccharum spp.) is a globally important crop for sugar and bioenergy production. Its highly polyploid, complex genome has hindered progress in understanding its molecular structure. Flow cytometric sorting and analysis has been used in other important crops with large genomes to dissect the genome into comp...

journal_title：Scientific reports

authors： Metcalfe CJ,Li J,Giorgi D,Doležel J,Piperidis N,Aitken KS

更新日期：2019-12-18 00:00:00

abstract：:The objective of this study was to determine if Ihh is required for fracture healing. Fibular fracture was created in adult Col2a1-CreERT2; Ihhfl/fl mice. Ihhfl/fl mice received Tamoxifen (TM) to delete Ihh. WT mice received Cyclopamine to inhibit Hh pathway. Callus tissue properties and Ihh pathway were analyzed at 1...

journal_title：Scientific reports

authors： Li S,Xiang C,Wei X,Li H,Li K,Sun X,Wang S,Zhang M,Deng J,Wang X,Li P,Li R,Zhang Y,Wei L

更新日期：2018-07-09 00:00:00

abstract：:Cell competition is a cell-cell interaction by which a cell compares its fitness to that of neighboring cells. The cell with the relatively lower fitness level is the "loser" and actively eliminated, while the cell with the relatively higher fitness level is the "winner" and survives. Recent studies have shown that ce...

journal_title：Scientific reports

authors： Chiba T,Ishihara E,Miyamura N,Narumi R,Kajita M,Fujita Y,Suzuki A,Ogawa Y,Nishina H

更新日期：2016-06-21 00:00:00

abstract：:Obstructive heart defects (OHDs) are a major health concern worldwide. The platelet-derived growth factor (PDGF) genes are known to have regulatory functions that are essential for proper heart development. In a zebrafish model, Pdgfra was further demonstrated to interact with ethanol during craniofacial development. ...

journal_title：Scientific reports

authors： Tang X,Eberhart JK,Cleves MA,Li J,Li M,MacLeod S,Nembhard WN,Hobbs CA

更新日期：2018-07-23 00:00:00

abstract：:Theoretical and experimental work has demonstrated that excitatory (E) and inhibitory (I) currents within cortical circuits stabilize to a balanced state. This E/I balance, observed from single neuron to network levels, has a fundamental role in proper brain function and its impairment has been linked to numerous brai...

journal_title：Scientific reports

authors： Shen K,Zeppillo T,Limon A

更新日期：2020-07-09 00:00:00

abstract：:Although increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis, the molecular mechanisms of pressure overload or AngII -induced cardiac interstitial fibrosis remain elusive. In this study, serpinE2/protease nexin-1 ...

journal_title：Scientific reports

authors： Li X,Zhao D,Guo Z,Li T,Qili M,Xu B,Qian M,Liang H,E X,Chege Gitau S,Wang L,Huangfu L,Wu Q,Xu C,Shan H

更新日期：2016-11-23 00:00:00

abstract：:We have designed a fully automated optical microscope running at high-speed and achieving a very high spatial resolution. In order to overcome the resolution limit of optical microscopes, it exploits the localized surface plasmon resonance phenomenon. The customized setup using a polarization analyzer, based on liquid...

journal_title：Scientific reports

authors： Alexandrov A,Asada T,De Lellis G,Di Crescenzo A,Gentile V,Naka T,Tioukov V,Umemoto A

更新日期：2020-11-02 00:00:00

abstract：:The benefits that physical exercise confers on cardiovascular health are well known, whereas the notion that physical exercise can also improve cognitive performance has only recently begun to be explored and has thus far yielded only controversial results. In the present study, we used a sample of young male subjects...

journal_title：Scientific reports

authors： Perini R,Bortoletto M,Capogrosso M,Fertonani A,Miniussi C

更新日期：2016-05-05 00:00:00

abstract：:Laser has been widely used in many aspects, by now it is difficult to get each frequency that we want, and frequency conversion is an effective way to obtain different frequency laser through a nonlinear optical crystal. MgO-doped LiNbO3 (Mg:LN) crystal has usually been used for second harmonic generation (SHG) throug...

journal_title：Scientific reports

authors： Kong T,Liu H,Ge X,Qu D,Liu S,Chen S,Zhang L,Kong Y,Rupp R,Xu J

更新日期：2018-03-01 00:00:00

abstract：:The physiological, biochemical and functional differences between oxidative and glycolytic muscles play important roles in human metabolic health and in animal meat quality. To explore these differences, we determined the genome-wide landscape of DNA methylomes and their relationship with the mRNA and miRNA transcript...

journal_title：Scientific reports

authors： Shen L,Du J,Xia Y,Tan Z,Fu Y,Yang Q,Li X,Tang G,Jiang Y,Wang J,Li M,Zhang S,Zhu L

更新日期：2016-08-26 00:00:00

abstract：:Inelastic electron tunneling spectroscopy is a powerful technique for investigating lattice dynamics of nanoscale systems including graphene and small molecules, but establishing a stable tunnel junction is considered as a major hurdle in expanding the scope of tunneling experiments. Hexagonal boron nitride is a pivot...

journal_title：Scientific reports

authors： Jung S,Park M,Park J,Jeong TY,Kim HJ,Watanabe K,Taniguchi T,Ha DH,Hwang C,Kim YS

更新日期：2015-11-13 00:00:00

abstract：:Little is known about the composition and clinical implications of lung microbiome in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia requiring invasive mechanical ventilation and intensive care unit admission. Therefore, this study aimed to explore the longitudinal changes ...

journal_title：Scientific reports

authors： Huang WC,Wu MF,Huang CC,Liu SY,Chen HC,Chen YY,Hsu JY,Huang CC

更新日期：2020-07-06 00:00:00

abstract：:Ge-monopnictides (GeAs) plays critical role in high-tech industry, especially in the field of advanced optical devices and infrared. As a secondary material, coal fly ash could be further recycled to retrieve germanium and prepare GeAs material with high added values. Hence, the aim of this paper is to propose a one-p...

journal_title：Scientific reports

authors： Zhang L,Xu Z

更新日期：2017-06-16 00:00:00