A novel signature for stratifying the molecular heterogeneity of the tissue-infiltrating T-cell receptor repertoire reflects gastric cancer prognosis.

abstract：:The Longwangzhuang pluton is a typical example of Paleoproterozoic A-type granite intrusions at the southern margin of the North China Craton. This pluton is composed of arfvedsonite granite and minor aegirine-augite granites. Samples from both granite types display similar zircon U-Pb ages with 207U-206Pb ages of 161...

journal_title：Scientific reports

authors： Wang Y,Yang YZ,Siebel W,Zhang H,Zhang YS,Chen F

更新日期：2020-01-09 00:00:00

abstract：:Testosterone is involved in male sexual, parental and aggressive behaviors through the androgen receptor (AR) and estrogen receptor (ER) α expressed in the brain. Although several studies have demonstrated that ERα and AR in the medial preoptic area (MPOA) are required for exhibiting sexual and aggressive behaviors of...

journal_title：Scientific reports

authors： Tsuneoka Y,Yoshida S,Takase K,Oda S,Kuroda M,Funato H

更新日期：2017-08-29 00:00:00

abstract：:Numerous researchers have expressed concern over the emerging water scarcity issues around the globe. Economic water scarcity is severe in the developing countries; thus, the use of inexpensive wastewater treatment strategies can help minimize this issue. An abundant amount of laundry wastewater (LWW) is generated dai...

journal_title：Scientific reports

authors： Yaseen ZM,Zigale TT,Tiyasha,D RK,Salih SQ,Awasthi S,Tung TM,Al-Ansari N,Bhagat SK

更新日期：2019-12-10 00:00:00

abstract：:Visceral adiposity is a risk factor for cardiovascular disorders, type 2 diabetes mellitus (T2D) and associated metabolic diseases. Sub-cutaneous fat is believed to be intrinsically different from visceral fat. To understand molecular mechanisms involved in metabolic advantages of fat transplantation, we studied a rat...

journal_title：Scientific reports

authors： Satoor SN,Puranik AS,Kumar S,Williams MD,Ghale M,Rahalkar A,Karandikar MS,Shouche Y,Patole M,Bhonde R,Yajnik CS,Hardikar AA

更新日期：2011-01-01 00:00:00

abstract：:Mitochondria-generated reactive oxygen species (mROS) are frequently associated with DNA damage and cell cycle arrest, but physiological increases in mROS serve to regulate specific cell functions. T3 is a major regulator of mROS, including hydrogen peroxide (H2O2). Here we show that exogenous thyroid hormone (T3) adm...

journal_title：Scientific reports

authors： Tan L,Bogush N,Naib H,Perry J,Calvert JW,Martin DIK,Graham RM,Naqvi N,Husain A

更新日期：2019-11-27 00:00:00

abstract：:The increasing demand for healthy baked goods boosted studies on sourdough microbiota with beneficial metabolic traits, to be used as potential functional starters. Here, 139 yeasts isolated from cereal-based fermented foods were in vitro characterized for their phytase and antioxidant activities. The molecular charac...

journal_title：Scientific reports

authors： Palla M,Blandino M,Grassi A,Giordano D,Sgherri C,Quartacci MF,Reyneri A,Agnolucci M,Giovannetti M

更新日期：2020-07-30 00:00:00

abstract：:Soil water retention curve (SWRC) plays an important role in simulating soil water movement and assessing soil water holding capacity and availability. Comparison of fitness between different models to determine the best SWRC model of specific regions is required. In this study, three popular models, van Genuchten, Br...

journal_title：Scientific reports

authors： Pan T,Hou S,Liu Y,Tan Q

更新日期：2019-12-05 00:00:00

abstract：:Avian influenza viruses (AIV) are classified into 16 hemagglutinin (HA; H1-H16) and 9 neuraminidase (NA; N1-N9) subtypes. All AIV are low pathogenic (LP) in birds, but subtypes H5 and H7 AIV can evolve into highly pathogenic (HP) forms. In the last two decades evolution of HPAIV H7 from LPAIV has been frequently repor...

journal_title：Scientific reports

authors： Scheibner D,Ulrich R,Fatola OI,Graaf A,Gischke M,Salaheldin AH,Harder TC,Veits J,Mettenleiter TC,Abdelwhab EM

更新日期：2019-08-09 00:00:00

abstract：:Nitrogen-doped graphene (N-graphene) has attractive properties that has been widely studied over the years. However, its possible formation process still remains unclear. Here, we propose a highly feasible formation mechanism of the graphitic-N doing in thermally treated graphene with ammonia by performing ab initio m...

journal_title：Scientific reports

authors： Li XF,Lian KY,Liu L,Wu Y,Qiu Q,Jiang J,Deng M,Luo Y

更新日期：2016-03-22 00:00:00

abstract：:Detailed measurements of physical, chemical and biological dynamics in groundwater are key to understanding the important processes in place and their influence on water quality - particularly when used for drinking water. Measuring temporal bacterial dynamics at high frequency is challenging due to the limitations in...

journal_title：Scientific reports

authors： Besmer MD,Epting J,Page RM,Sigrist JA,Huggenberger P,Hammes F

更新日期：2016-12-07 00:00:00

abstract：:Despite the development of crystal engineering, it remains a great challenge to predict the crystal structure even for the simplest molecules, and a clear link between molecular and crystal symmetry is missing in general. Here we demonstrate that the two-dimensional (2D) crystallization of heterocirculenes on a Au(111...

journal_title：Scientific reports

authors： Xiao WD,Zhang YY,Tao L,Aït-Mansour K,Chernichenko KY,Nenajdenko VG,Ruffieux P,Du SX,Gao HJ,Fasel R

更新日期：2014-06-24 00:00:00

abstract：:The high hydrophobicity of poly(vinylidene fluoride) (PVDF) membrane remains an obstacle to be applied in some purification processes of water or wastewater. Herein, a highly hydrophilic hybrid mesoporous titania membrane composed of mesoporous anatase titania (meso-TiO2) materials inside the three-dimensional (3D) ma...

journal_title：Scientific reports

authors： Wang M,Yang G,Jin P,Tang H,Wang H,Chen Y

更新日期：2016-01-12 00:00:00

abstract：:The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships. In the present study, we evaluated the influence of visual impairment on depression in all age groups using a longitudinal database of a nationa...

journal_title：Scientific reports

authors： Choi HG,Lee MJ,Lee SM

更新日期：2018-02-01 00:00:00

abstract：:In eusocial Hymenoptera (ants, bees and wasps), queen and worker adult castes typically arise via environmental influences. A fundamental challenge is to understand how a single genome can thereby produce alternative phenotypes. A powerful approach is to compare the molecular basis of caste determination and different...

journal_title：Scientific reports

authors： Collins DH,Mohorianu I,Beckers M,Moulton V,Dalmay T,Bourke AF

更新日期：2017-03-31 00:00:00

abstract：:In a globalized world, plant invasions are common challenges for native ecosystems. Although a considerable number of invasive plants form arbuscular mycorrhizae, interactions between arbuscular mycorrhizal (AM) fungi and invasive and native plants are not well understood. In this study, we conducted a greenhouse expe...

journal_title：Scientific reports

authors： Řezáčová V,Řezáč M,Gryndlerová H,Wilson GWT,Michalová T

更新日期：2020-11-20 00:00:00

abstract：:Chrysopidae (green lacewings) is the second largest family in Neuroptera, and it includes medium-size lacewings largely recognized by the presence of golden-colored eyes, bright green bodies and delicate wings with dense venation patterns. The subfamily Chrysopinae includes 97% of the species diversity in the family a...

journal_title：Scientific reports

authors： Jiang Y,Garzón-Orduña IJ,Winterton SL,Yang F,Liu X

更新日期：2017-08-03 00:00:00

abstract：:Scaling evolutionary trees to time is essential for understanding the origins of clades. Recently developed methods allow including the entire fossil record known for the group of interest and eliminated the need for specifying prior distributions for node ages. Here we apply the fossilized birth-death (FBD) approach ...

journal_title：Scientific reports

authors： Šmíd J,Tolley KA

更新日期：2019-04-02 00:00:00

abstract：:Calcium oxalate monohydrate (COM) crystals cause kidney stone disease by still unclear mechanisms. The present study aimed to characterize changes in secretion of proteins from basolateral compartment of renal tubular epithelial cells after exposure to COM crystals and then correlated them with the stone pathogenesis....

journal_title：Scientific reports

authors： Chiangjong W,Thongboonkerd V

更新日期：2016-04-05 00:00:00

abstract：:Divalent metal-ion transporter 1 (DMT1) has been found to play an important role in the iron metabolism and hemogenesis. However, little is known about the potential role of DMT1 in the pathogenesis of anemia from patients with inflammatory bowel disease (IBD). Herein, we investigated expression of DMT1 in the intesti...

journal_title：Scientific reports

authors： Wu W,Song Y,He C,Liu C,Wu R,Fang L,Cong Y,Miao Y,Liu Z

更新日期：2015-11-17 00:00:00

abstract：:The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate...

journal_title：Scientific reports

authors： Wang CY,Xia JG,Yang ZQ,Zhou WZ,Chen WH,Qi CJ,Gu JP,Wang Q

更新日期：2020-03-10 00:00:00

abstract：:The aim of this study was to compare the effects of an aerobic training program with a strength training program on body composition and energy expenditure in overweight or obese (29.06 ± 3.49 kg/m2) young adults (21.96 ± 1.90 years). Subjects (N = 109) were randomly assigned to one of three groups: a control group (C...

journal_title：Scientific reports

authors： Fernández-García JC,Gálvez-Fernández I,Mercadé-Melé P,Gavala-González J

更新日期：2020-03-24 00:00:00

abstract：:Metabolic syndrome, including obesity and insulin resistance, has been reported to lower lung function in elderly subjects with asthma or chronic obstructive lung disease. This study aimed to find the association between lung function and insulin resistance in Korean young adults. This study used data from the Korean ...

journal_title：Scientific reports

authors： Lee YB,Kim YS,Lee DH,Kim HY,Lee JI,Ahn HS,Sohn TS,Lee TK,Song JY,Yeo CD,Hong M,Han K,Jeong SC,Chae HS

更新日期：2017-09-15 00:00:00

abstract：:Membrane type 1 metalloproteinase (MT1-MMP) is an important regulator of cancer invasion, growth and angiogenesis, thus making it an attractive target for cancer imaging and therapy. A non-substrate peptide (MT1-AF7p) that bonded to the "MT-Loop" region of MT1-MMP was identified by using a phage-displayed peptide libr...

journal_title：Scientific reports

authors： Ren L,Wang Y,Zhu L,Shen L,Zhang J,Wang J,Li H,Zheng Q,Yu D,Fang X

更新日期：2018-07-09 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Yu K,Lu F,Li Q,Chen H,Lu B,Liu J,Li Z,Dai F,Wu D,Lan G

更新日期：2018-01-22 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

journal_title：Scientific reports

authors： Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

更新日期：2019-10-10 00:00:00

abstract：:Waddlia chondrophila is a Gram-negative intracellular bacterial organism that is related to classical chlamydial species and has been implicated as a cause of abortion in cattle. Despite an increasing number of observational studies linking W. chondrophila infection to cattle abortion, little direct experimental evide...

journal_title：Scientific reports

authors： Wheelhouse N,Flockhart A,Aitchison K,Livingstone M,Finlayson J,Flachon V,Sellal E,Dagleish MP,Longbottom D

更新日期：2016-11-14 00:00:00

abstract：:Large-scale anthropogenic disturbances can have direct and indirect effects on marine communities, with direct effects often taking the form of widespread injury or mortality and indirect effects manifesting as changes in food web structure. Here, we report a time series that captures both direct and indirect effects ...

journal_title：Scientific reports

authors： Lewis JP,Tarnecki JH,Garner SB,Chagaris DD,Patterson WF 3rd

更新日期：2020-04-09 00:00:00

abstract：:Immune responses against gene therapy products limit its therapeutic efficacy and present a safety risk. Identification of agents that blunt immune reactions may aid in developing novel immunomodulatory therapies. Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibit...

journal_title：Scientific reports

authors： Baer A,Colon-Moran W,Bhattarai N

更新日期：2018-07-19 00:00:00

abstract：:Owing to the diversity of pulse-wave morphology, pulse-based diagnosis is difficult, especially pulse-wave-pattern classification (PWPC). A powerful method for PWPC is a convolutional neural network (CNN). It outperforms conventional methods in pattern classification due to extracting informative abstraction and featu...

journal_title：Scientific reports

authors： Li G,Watanabe K,Anzai H,Song X,Qiao A,Ohta M

更新日期：2019-10-17 00:00:00

abstract：:The structural and mechanical properties of tissue and the interplay between them play a critical role in tissue function. We introduce the optomechanogram, a combined quantitative and qualitative visualization of spatially co-registered measurements of the microstructural and micromechanical properties of any tissue....

journal_title：Scientific reports

authors： Lee W,Ostadi Moghaddam A,Shen S,Phillips H,McFarlin BL,Wagoner Johnson AJ,Toussaint KC Jr

更新日期：2021-01-11 00:00:00