Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis.

abstract：:Floating macrophytes, including water hyacinth (Eichhornia crassipes), are dominant invasive organisms in tropical aquatic systems, and they may play an important role in modifying the gas exchange between water and the atmosphere. However, these systems are underrepresented in global datasets of greenhouse gas (GHG) ...

journal_title：Scientific reports

authors： Attermeyer K,Flury S,Jayakumar R,Fiener P,Steger K,Arya V,Wilken F,van Geldern R,Premke K

更新日期：2016-02-05 00:00:00

abstract：:Spliced leader dependent trans-splicing (SLTS) has been described as an important RNA regulatory process that occurs in different organisms, including the trematode Schistosoma mansoni. We identified more than seven thousand putative SLTS sites in the parasite, comprising genes with a wide spectrum of functional class...

journal_title：Scientific reports

authors： Boroni M,Sammeth M,Gava SG,Jorge NAN,Macedo AM,Machado CR,Mourão MM,Franco GR

更新日期：2018-03-01 00:00:00

abstract：:A bound state in the continuum (BIC) is an unusual localized state that is embedded in a continuum of extended states. Here, we present the general condition for BICs to arise from wave equation separability. Then we show that by exploiting perturbations of certain symmetry such BICs can be turned into resonances that...

journal_title：Scientific reports

authors： Rivera N,Hsu CW,Zhen B,Buljan H,Joannopoulos JD,Soljačić M

更新日期：2016-09-19 00:00:00

abstract：:Compact silicon integrated lasers are of significant interest for various applications. We present a detailed investigation for realizing sub-mm long on-chip laser structures operating at λ = 1.533 µm on the silicon-on-insulator photonic platform by combining a multi-segment silicon waveguide structure and a recently ...

journal_title：Scientific reports

authors： Tu Z,Zhang J,Rönn J,Alonso-Ramos C,Leroux X,Vivien L,Sun Z,Cassan É

更新日期：2020-07-02 00:00:00

abstract：:2D transition metal dichalcogenides (TMDs) have attracted a lot of attention recently for energy-efficient tunneling-field-effect transistor (TFET) applications due to their excellent gate control resulting from their atomically thin dimensions. However, most TMDs have bandgaps (Eg) and effective masses (m(*)) outside...

journal_title：Scientific reports

authors： Ameen TA,Ilatikhameneh H,Klimeck G,Rahman R

更新日期：2016-06-27 00:00:00

abstract：:The precision and accuracy of quantifying semi-volatile organic compounds (SVOCs) in solution by GC/MS, particularly when volume errors are unpredictable or difficult to control, are improved by utilizing internal standards (IS). Not obvious though is the extent to which timing IS addition affects measurement. To illu...

journal_title：Scientific reports

authors： Otim O,Rocha J Jr

更新日期：2020-10-19 00:00:00

abstract：:Studies suggest that chromium deficiency is associated with elevated levels of fasting blood glucose, circulating insulin, cholesterol and triglycerides, and decreased proportion of lean body mass. However, data directly relating chromium levels to metabolic syndrome (MetS) risk are lacking. A total of 3,648 American ...

journal_title：Scientific reports

authors： Bai J,Xun P,Morris S,Jacobs DR Jr,Liu K,He K

更新日期：2015-10-22 00:00:00

abstract：:Emergence of DS-1-like-G1P[8] rotavirus in Asia have been recently reported. We report for the first time the detection and the whole genome phylogenetic analysis of DS-1-like-G1P[8] strains in America. From 2013 to 2017, a total of 4226 fecal samples were screened for rotavirus by ELISA, PAGE, RT-PCR and sequencing. ...

journal_title：Scientific reports

authors： Luchs A,da Costa AC,Cilli A,Komninakis SCV,Carmona RCC,Morillo SG,Sabino EC,Timenetsky MDCST

更新日期：2019-02-18 00:00:00

abstract：:This study aims to prepare, characterize and evaluate the pharmacokinetics of liposomal donepezil HCl (LDH) dispersed into thiolated chitosan hydrogel (TCH) in rabbits. Various hydrogels including TCH were prepared, and after characterization, TCH was selected for subsequent evaluations, due to the promising results. ...

journal_title：Scientific reports

authors： Al Harthi S,Alavi SE,Radwan MA,El Khatib MM,AlSarra IA

更新日期：2019-07-02 00:00:00

abstract：:Stable electroluminescence from micro-pixelated light-emitting diode (μLED) occurs when electrons and holes are continuously injected from external electrodes. Different from the general recognition, in this work, μLED works in an operation mode, namely, non-electrical contact and non-carrier injection mode, and can b...

journal_title：Scientific reports

authors： Wang K,Liu Y,Wu C,Li D,Lv S,Zhang Y,Zhou X,Guo T

更新日期：2020-05-15 00:00:00

abstract：:The Na+;HCO3- co-transporter NBCn1 (SLC4A7) is a major regulator of intracellular pH yet its trafficking and turnover are essentially unstudied. Here, we used MDCK-II and MCF-7 cells to investigate these processes in epithelial cells. GFP-NBCn1 membrane localization was abolished by truncation of the full NBCn1 C-term...

journal_title：Scientific reports

authors： Olesen CW,Vogensen J,Axholm I,Severin M,Schnipper J,Pedersen IS,von Stemann JH,Schrøder JM,Christensen DP,Pedersen SF

更新日期：2018-05-09 00:00:00

abstract：:The capacity of graphene oxide nanoparticles (nGOx) to reduce or increase As and metals availability in polluted soils was compared with that of zero valent iron nanoparticles (nZVI). The nanomaterials used in this study were characterized by X-ray techniques, CHNS-O analysis, dynamic light scattering, and microscopy ...

journal_title：Scientific reports

authors： Baragaño D,Forján R,Welte L,Gallego JLR

更新日期：2020-02-05 00:00:00

abstract：:The population of hepatitis B combined with a number of metabolic disorders is increasing significantly. Resveratrol (RSV) has been used as a preclinical drug for the treatment of the metabolic disorders. However, the impact of RSV on HBV replication remains unknown. In this study, the HBV-expressing hepatocelluar car...

journal_title：Scientific reports

authors： Shi Y,Li Y,Huang C,Ying L,Xue J,Wu H,Chen Z,Yang Z

更新日期：2016-04-21 00:00:00

abstract：:Plasmonic metamaterials have overcome fundamental limitations in conventional optics by their capability to engineer material resonances and dispersions at will, holding great promise for sensing applications. Recent demonstrations of metamaterial sensors, however, have mainly relied on their resonant nature for stron...

journal_title：Scientific reports

authors： Ishikawa A,Hara S,Tanaka T,Hayashi Y,Tsuruta K

更新日期：2017-06-09 00:00:00

abstract：:The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which genes and signalling pathways regulate their development is crucial for understanding developmental disorders as well as diseases in adulthood. We exploited unique...

journal_title：Scientific reports

authors： Trubiroha A,Gillotay P,Giusti N,Gacquer D,Libert F,Lefort A,Haerlingen B,De Deken X,Opitz R,Costagliola S

更新日期：2018-04-04 00:00:00

abstract：:Novel bioplastic films derived from wool keratins were prepared by protein solution in an alkaline mild oxidative method that splits disulphide (-S-S-) bonds. The native structure of the keratin macromolecules was partially modified upon extraction as revealed by the decrease of the β-sheet to α-helices/coils ratio bu...

journal_title：Scientific reports

authors： Fernández-d'Arlas B

更新日期：2019-10-15 00:00:00

abstract：:Oxygen-induced retinopathy (OIR) upregulates Müller cell vascular endothelial growth factor A (VEGFA) that causes intravitreal neovascularization similar to severe retinopathy of prematurity (ROP). Safety concerns exist with anti-VEGF treatment for ROP. We evaluated long-term knockdown of Müller cell-VEGFA with short-...

journal_title：Scientific reports

authors： Becker S,Wang H,Simmons AB,Suwanmanee T,Stoddard GJ,Kafri T,Hartnett ME

更新日期：2018-01-31 00:00:00

abstract：:Dissolved organic carbon (DOC) concentrations and water colour are increasing in many inland waters across northern Europe and northeastern North America. This inland-water "browning" has profound physical, chemical and biological repercussions for aquatic ecosystems affecting water quality, biological community struc...

journal_title：Scientific reports

authors： Meyer-Jacob C,Michelutti N,Paterson AM,Cumming BF,Keller WB,Smol JP

更新日期：2019-11-13 00:00:00

abstract：:Twisting light in both phase and intensity has recently drawn great interests in various fields related to light-matter interactions such as optical manipulation of particles and quantum entanglement of photons. Conventionally, bulky optical components are required to produce such twisted optical beams, which signific...

journal_title：Scientific reports

authors： Zhang Y,Yang X,Gao J

更新日期：2018-03-20 00:00:00

abstract：:Scaling evolutionary trees to time is essential for understanding the origins of clades. Recently developed methods allow including the entire fossil record known for the group of interest and eliminated the need for specifying prior distributions for node ages. Here we apply the fossilized birth-death (FBD) approach ...

journal_title：Scientific reports

authors： Šmíd J,Tolley KA

更新日期：2019-04-02 00:00:00

abstract：:The apolipoprotein B mRNA editing catalytic polypeptide-like (APOBEC) family proteins bind RNA and single-stranded DNA, and create C-to-U base modifications through cytidine deaminase activity. APOBEC3G restricts human immunodeficiency virus 1 (HIV-1) infection by creating hypermutations in proviral DNA, while HIV-1-e...

journal_title：Scientific reports

authors： Chen R,Zhao X,Wang Y,Xie Y,Liu J

更新日期：2017-01-18 00:00:00

abstract：:We construct two families of orthogonal product quantum states that cannot be exactly distinguished by local operation and classical communication (LOCC) in the quantum system of (2k+i) ⊗ (2l+j) (i, j ∈ {0, 1} and i ≥ j ) and (3k+i) ⊗ (3l+j) (i, j ∈ {0, 1, 2}). And we also give the tiling structure of these two famili...

journal_title：Scientific reports

authors： Zhang X,Tan X,Weng J,Li Y

更新日期：2016-07-05 00:00:00

abstract：:Accurate measurements of autonomic nerve regulation in heart failure (HF) were unresolved. The discriminating performance of deceleration and acceleration capacities of heart rate in HF was evaluated in 130 HF patients and 212 controls. Acceleration capacity and deceleration capacity were independent risk factors for ...

journal_title：Scientific reports

authors： Hu W,Jin X,Zhang P,Yu Q,Yin G,Lu Y,Xiao H,Chen Y,Zhang D

更新日期：2016-03-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Bruneau N,Toumi R,Wang S

更新日期：2018-04-17 00:00:00

abstract：:Reciprocity is frequently assumed to require complex cognitive abilities. Therefore, it has been argued that reciprocity may be restricted to animals that can meet these demands. Here, we provide evidence for the potential presence of direct reciprocity in teleost fishes. We demonstrate that in pairs of coral reef rab...

journal_title：Scientific reports

authors： Brandl SJ,Bellwood DR

更新日期：2015-09-25 00:00:00

abstract：:Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder, and the exact causal mechanism is unknown. Dysregulated allele-specific expression (ASE) has been identified in persons with ASD; however, a comprehensive analysis of ASE has not been conducted in a family quartet with ASD. To fill this ...

journal_title：Scientific reports

authors： Lin CY,Chang KW,Lin CY,Wu JY,Coon H,Huang PH,Ho HN,Akbarian S,Gau SS,Huang HS

更新日期：2018-03-09 00:00:00

abstract：:Resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has become the main clinical challenge of advanced lung cancer. This research aimed to explore the role of PARP1-mediated autophagy in the progression of TKI therapy. PARP1-mediated autophagy was evaluated in vitro by CCK-8 assay, cl...

journal_title：Scientific reports

authors： Zhang Z,Lian X,Xie W,Quan J,Liao M,Wu Y,Yang ZZ,Wang G

更新日期：2020-12-01 00:00:00

abstract：:Temperature index (TI) models are convenient for modelling glacier ablation since they require only a few input variables and rely on simple empirical relations. The approach is generally assumed to be reliable at lower elevations (below 3500 m above sea level, a.s.l) where air temperature (Ta) relates well to the ene...

journal_title：Scientific reports

authors： Litt M,Shea J,Wagnon P,Steiner J,Koch I,Stigter E,Immerzeel W

更新日期：2019-03-27 00:00:00

abstract：:Following radiation induced DNA damage, several repair pathways are activated to help preserve genome integrity. Double Strand Breaks (DSBs), which are highly toxic, have specified repair pathways to address them. The main repair pathways used to resolve DSBs are Non-Homologous End Joining (NHEJ) and Homologous Recomb...

journal_title：Scientific reports

authors： Ingram SP,Warmenhoven JW,Henthorn NT,Smith EAK,Chadwick AL,Burnet NG,Mackay RI,Kirkby NF,Kirkby KJ,Merchant MJ

更新日期：2019-04-23 00:00:00

abstract：:HCV NS3 protein plays a central role in viral polyprotein processing and RNA replication. We demonstrate that the NS3 protease (NS3(pro)) domain alone can specifically bind to HCV-IRES RNA, predominantly in the SLIV region. The cleavage activity of the NS3 protease domain is reduced upon HCV-RNA binding. More importan...

journal_title：Scientific reports

authors： Ray U,Das S

更新日期：2011-01-01 00:00:00