Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes.

abstract：:Early detection of cancer is essential for effective intervention. Urine has been used to reflect early changes in various tumor-bearing models. However, urine has not been used to predict whether tumors will form in animal models. In this study, a cancer model was established by tail vein injection of 2 million NuTu-...

journal_title：Scientific reports

authors： Wei J,Ni N,Meng W,Huan Y,Gao Y

更新日期：2020-07-16 00:00:00

abstract：:High temperature inhibits wheat grain filling. Polyamines (PAs) are closely associated with plant resistance caused by abiotic stress. However, little is known about the effect of PAs on the grain filling of wheat under heat stress. Two wheat varieties differing in heat resistance were used, and endogenous PAs levels ...

journal_title：Scientific reports

authors： Jing J,Guo S,Li Y,Li W

更新日期：2020-05-04 00:00:00

abstract：:Low phase noise mode-locked fiber laser finds important applications in telecommunication, ultrafast sciences, material science, and biology, etc. In this paper, two types of carbon nano-materials, i.e. single-wall carbon nanotube (SWNT) and graphene oxide (GO), are investigated as efficient saturable absorbers (SAs) ...

journal_title：Scientific reports

authors： Li X,Wu K,Sun Z,Meng B,Wang Y,Wang Y,Yu X,Yu X,Zhang Y,Shum PP,Wang QJ

更新日期：2016-04-29 00:00:00

abstract：:Understanding interactions between cell-penetrating peptides and biomembrane under tension can help improve drug delivery and elucidate mechanisms underlying fundamental cellular events. As far as the effect of membrane tension on translocation, it is generally thought that tension should disorder the membrane structu...

journal_title：Scientific reports

authors： He X,Lin M,Sha B,Feng S,Shi X,Qu Z,Xu F

更新日期：2015-08-03 00:00:00

abstract：:Bark beetles often serve as forest damaging agents, causing landscape-level mortality. Understanding the biology and ecology of beetles are important for both, gathering knowledge about important forest insects and forest protection. Knowledge about the bark beetle gut-associated bacteria is one of the crucial yet sur...

journal_title：Scientific reports

authors： Chakraborty A,Ashraf MZ,Modlinger R,Synek J,Schlyter F,Roy A

更新日期：2020-10-29 00:00:00

abstract：:A subwoofer generates the lowest frequency range in loudspeaker systems. Subwoofers are used in audio systems for live concerts, movie theatres, home theatres, gaming consoles, cars, etc. During the last decades, numerical simulations have emerged as a cost- and time-efficient complement to traditional experiments in ...

journal_title：Scientific reports

authors： Bokhari AH,Berggren M,Noreland D,Wadbro E

更新日期：2021-01-08 00:00:00

abstract：:Evolutionary processes, speciation in woody bamboos are presently little understood. Here we used Dendrocalamus sinicus Chia & J.L. Sun as a model species to investigate dispersal or vicariance speciation in woody bamboos. Variation in three chloroplast DNA (cpDNA) fragments and eight simple sequence repeat markers (S...

journal_title：Scientific reports

authors： Yang JB,Dong YR,Wong KM,Gu ZJ,Yang HQ,Li Z

更新日期：2018-11-16 00:00:00

abstract：:Aluminium nitride (AlN) is a promising semiconductor material for use as a substrate in high-power, high-frequency electronic and deep-ultraviolet optoelectronic devices. We study the feasibility of a novel AlN fabrication technique by using the Al/GaN substitution reaction method. The substitution method we propose h...

journal_title：Scientific reports

authors： Noorprajuda M,Ohtsuka M,Adachi M,Fukuyama H

更新日期：2020-08-03 00:00:00

abstract：:Mulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Labora...

journal_title：Scientific reports

authors： Rehman M,Liu J,Johnson AC,Dada TE,Gurr GM

更新日期：2019-10-16 00:00:00

abstract：:The association between perioperative blood transfusion (PBT) with adverse oncological outcomes have been previously reported in multiple malignancies including RCC. Nevertheless, the importance of transfusion timing is still unclear. The primary purpose of this study is to appraise whether the receipt of intraoperati...

journal_title：Scientific reports

authors： Abu-Ghanem Y,Dotan Z,Zilberman DE,Kaver I,Ramon J

更新日期：2019-02-04 00:00:00

abstract：:Atherosclerosis is a chronic inflammatory disease characterized by the infiltration of pro-inflammatory macrophages into a lipid-laden plaque. ITCH is an E3 ubiquitin ligase that has been shown to polarize macrophages to an anti-inflammatory phenotype. We therefore investigated the effect of ITCH deficiency on the dev...

journal_title：Scientific reports

authors： Stöhr R,Mavilio M,Marino A,Casagrande V,Kappel B,Möllmann J,Menghini R,Melino G,Federici M

更新日期：2015-03-17 00:00:00

abstract：:We analysed suppressive effects of potassium (K) fertilisation on radiocesium (137Cs) uptake by hinoki cypress (Chamaecyparis obtusa) seedlings from soils contaminated after the Fukushima Daiichi Nuclear Power Plant accident. Three-year-old seedlings were planted in a clear-cut forest (ca. 4 ha) during June-July 2014,...

journal_title：Scientific reports

authors： Komatsu M,Hirai K,Nagakura J,Noguchi K

更新日期：2017-11-15 00:00:00

abstract：:This observational study investigated the impact of hyponatremia resolution on the results of a comprehensive geriatric assessment (CGA) in 150 patients with age ≥70 years and serum sodium <130 mEq/L. The test battery including Barthel index of Activities of Daily Living (ADL) and various tests of neurocognitive funct...

journal_title：Scientific reports

authors： Brinkkoetter PT,Grundmann F,Ghassabeh PJ,Becker I,Johnsen M,Suaréz V,Schulz RJ,Streichert T,Burst V

更新日期：2019-08-29 00:00:00

abstract：:Fluorescence visualization devices (FVs) are useful for detecting malignant lesions because of their simple and noninvasive application. However, their quantitative application has been challenging. This study aimed to quantitatively and statistically evaluate the change in fluorescence intensity (FI) during the progr...

journal_title：Scientific reports

authors： Kosugi A,Kasahara M,Yang L,Nakamura-Takahashi A,Shibahara T,Mori T

更新日期：2019-05-24 00:00:00

abstract：:Human travel impacts the spread of infectious diseases across spatial and temporal scales, with broad implications for the biological and social sciences. Individual data on travel patterns have been difficult to obtain, particularly in low-income countries. Travel survey data provide detailed demographic information,...

journal_title：Scientific reports

authors： Wesolowski A,Stresman G,Eagle N,Stevenson J,Owaga C,Marube E,Bousema T,Drakeley C,Cox J,Buckee CO

更新日期：2014-07-14 00:00:00

abstract：:Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists for calling locus-specific amplifications and deletions in each patient sample. Here, we report the correlative analysis of copy number amplitude and length wi...

journal_title：Scientific reports

authors： Roszik J,Wu CJ,Siroy AE,Lazar AJ,Davies MA,Woodman SE,Kwong LN

更新日期：2016-01-20 00:00:00

abstract：:Understanding the chemical and physical properties of metal/graphene oxide (M/GO) interfaces is important when GO is used in electronic and electrochemical devices because the metal layer must be firmly attached to GO. Here, permeation of metal from the surface into GO paper bulk at the M/GO interface was observed at ...

journal_title：Scientific reports

authors： Ogata C,Koinuma M,Hatakeyama K,Tateishi H,Asrori MZ,Taniguchi T,Funatsu A,Matsumoto Y

更新日期：2014-01-13 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection promotes a generalized activation of host responses that involves not only CD4 T cells, but also cells of the microenvironment, which are not directly infected, such as endothelial cells. The mechanisms triggering HIV-1-associated vascular alterations remain poorly...

journal_title：Scientific reports

authors： Balducci E,Leroyer AS,Lacroix R,Robert S,Todorova D,Simoncini S,Lyonnet L,Chareyre C,Zaegel-Faucher O,Micallef J,Poizot-Martin I,Roll P,Dignat-George F

更新日期：2019-07-16 00:00:00

abstract：:Most of the current studies on myocardial strain are mainly applied in patients with sinus rhythm because the image quality of arrhythmias obtained with conventional scanning sequences does not meet diagnostic needs. Here, we intend to assess left ventricular (LV) global myocardial strain in patients with arrhythmias ...

journal_title：Scientific reports

authors： Chen H,Xie RM,Zhao L,Zhang XY,Zhao YK,Wang Z,Xie GX,Ma XH

更新日期：2020-06-09 00:00:00

abstract：:Large consortia efforts and genome-wide association studies (GWASs) have linked a number of genetic variants within the 6p21 chromosomal region to non-Hodgkin lymphoma (NHL). Complementing these efforts, we genotyped previously reported SNPs in the human leukocyte antigen (HLA) class I (rs6457327) and class II (rs9271...

journal_title：Scientific reports

authors： Ten LC,Chin YM,Tai MC,Chin EF,Lim YY,Suthandiram S,Chang KM,Ong TC,Bee PC,Mohamed Z,Gan GG,Ng CC

更新日期：2017-01-31 00:00:00

abstract：:Transplantation of cardiomyocytes derived from induced pluripotent stem cell (iPSC-CMs) is a promising approach for increasing functional CMs during end-stage heart failure. Although major histocompatibility complex (MHC) class I matching between donor cells and recipient could reduce acquired immune rejection, innate...

journal_title：Scientific reports

authors： Nakamura Y,Miyagawa S,Yoshida S,Sasawatari S,Toyofuku T,Toda K,Sawa Y

更新日期：2019-07-25 00:00:00

abstract：:Optical thermometry has been widely studied to achieve an inaccessible temperature measurement in submicron scale and it has been reported that the temperature sensitivity depends mainly on host types. In this work, we propose a new method to improve the optical temperature sensitivity of Yb3+-Er3+ co-doped CaWO4 phos...

journal_title：Scientific reports

authors： Wang X,Wang Y,Bu Y,Yan X,Wang J,Cai P,Vu T,Seo HJ

更新日期：2017-02-27 00:00:00

abstract：:Low-dimensional semiconductor structurers formed on a substrate surface at pre-defined locations and with nano-precision placement is of vital interest. The potential of tailoring their electrical and optical properties will revolutionize the next generation of optoelectronic devices. Traditionally, highly aligned sel...

journal_title：Scientific reports

authors： Dushaq G,Rasras M

更新日期：2019-10-02 00:00:00

abstract：:Schistosomes, unlike malaria parasites, are in their diploid stage when targeted by the human immune system. Diploids can be either homozygous or heterozygous. The difference has profound significance for developing immunity and yet has not previously been addressed. We examined the implications of zygosity on immunit...

journal_title：Scientific reports

authors： Xu X,Sun J,Zhang J,Wellems D,Qing X,McCutchan T,Pan W

更新日期：2012-01-01 00:00:00

abstract：:Since the world population is ageing, dementia is going to be a growing concern. Alzheimer's disease is the most common form of dementia. The pathogenesis of Alzheimer's disease is extensively studied, yet unknown remains. Therefore, we aimed to extract new knowledge from existing data. We analysed about 2700 upregula...

journal_title：Scientific reports

authors： Hosseinian S,Arefian E,Rakhsh-Khorshid H,Eivani M,Rezayof A,Pezeshk H,Marashi SA

更新日期：2020-05-20 00:00:00

abstract：:Natural variability in pH in the diffusive boundary layer (DBL), the discrete layer of seawater between bulk seawater and the outer surface of organisms, could be an important factor determining the response of corals and coralline algae to ocean acidification (OA). Here, two corals with different morphologies and one...

journal_title：Scientific reports

authors： Comeau S,Cornwall CE,Pupier CA,DeCarlo TM,Alessi C,Trehern R,McCulloch MT

更新日期：2019-09-06 00:00:00

abstract：:Breast cancer susceptibility gene 1 (BRCA1) located at chromosome 17q12-21 is a classic tumor suppressor gene, and has been considered as a significant role in hereditary breast cancers. Moreover, numerous studies demonstrated the methylation status of CpG islands in the promoter regions of BRCA1 gene was aberrant in ...

journal_title：Scientific reports

authors： Zhang L,Long X

更新日期：2015-12-08 00:00:00

abstract：:This study investigates the immune responses induced by metal-filled single-walled carbon nanotubes (SWCNT) under in vitro, ex vivo and in vivo settings. Either empty amino-functionalized CNTs [SWCNT-NH2 (1)] or samarium chloride-filled amino-functionalized CNTs with [SmCl3@SWCNT-mAb (3)] or without [SmCl3@SWCNT-NH2 (...

journal_title：Scientific reports

authors： Perez Ruiz de Garibay A,Spinato C,Klippstein R,Bourgognon M,Martincic M,Pach E,Ballesteros B,Ménard-Moyon C,Al-Jamal KT,Tobias G,Bianco A

更新日期：2017-02-15 00:00:00

abstract：:Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of ...

journal_title：Scientific reports

authors： Obana A,Gohto Y,Gellermann W,Ermakov IV,Sasano H,Seto T,Bernstein PS

更新日期：2019-06-27 00:00:00

abstract：:Prasinophytes are a paraphyletic group of nine lineages of green microalgae that are currently classified either at the class or order level or as clades without formal taxonomic description. Prasinophyte clade VII comprises picoplanktonic algae that are important components of marine phytoplankton communities, partic...

journal_title：Scientific reports

authors： Lopes Dos Santos A,Pollina T,Gourvil P,Corre E,Marie D,Garrido JL,Rodríguez F,Noël MH,Vaulot D,Eikrem W

更新日期：2017-10-25 00:00:00