Abstract：
:Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of an ophthalmology clinic (577 men, 408 women, mean age of 69.7 ± 13.6 [SD]). Skin carotenoid (SC) and macular pigment (MP) levels were measured with reflection spectroscopy and autofluorescence imaging methods, respectively. The mean SC index was 343.1 ± 142.1 (SD). SC indices for women were higher than for men (382 vs 315, p < 0.001). Smokers and overweight subjects (BMI ≥ 25) had lower SC indices. Subjects taking lutein supplements had higher SC indices than non-supplementing subjects (415 vs 325, p < 0.001). SC and MP indices were significantly correlated. The obtained data set can be used for reference purposes by Japanese subjects and researchers interested in tissue responses to diets high in carotenoids and lutein supplementation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Obana A,Gohto Y,Gellermann W,Ermakov IV,Sasano H,Seto T,Bernstein PSdoi
10.1038/s41598-019-45751-6subject
Has Abstractpub_date
2019-06-27 00:00:00pages
9318issue
1issn
2045-2322pii
10.1038/s41598-019-45751-6journal_volume
9pub_type
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