Abstract:
:Human travel impacts the spread of infectious diseases across spatial and temporal scales, with broad implications for the biological and social sciences. Individual data on travel patterns have been difficult to obtain, particularly in low-income countries. Travel survey data provide detailed demographic information, but sample sizes are often small and travel histories are hard to validate. Mobile phone records can provide vast quantities of spatio-temporal travel data but vary in spatial resolution and explicitly do not include individual information in order to protect the privacy of subscribers. Here we compare and contrast both sources of data over the same time period in a rural area of Kenya. Although both data sets are able to quantify broad travel patterns and distinguish regional differences in travel, each provides different insights that can be combined to form a more detailed picture of travel in low-income settings to understand the spread of infectious diseases.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Wesolowski A,Stresman G,Eagle N,Stevenson J,Owaga C,Marube E,Bousema T,Drakeley C,Cox J,Buckee COdoi
10.1038/srep05678subject
Has Abstractpub_date
2014-07-14 00:00:00pages
5678issn
2045-2322pii
srep05678journal_volume
4pub_type
杂志文章abstract::This work highlights the possibility of using microstructured fibres with predefined doped regions to produce functional microstructures at a fibre facet with differential chemical etching. A specially designed silica microstructured fibre (MSF) that possesses specific boron-doped silica regions was fabricated for the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21279
更新日期:2016-02-19 00:00:00
abstract::Technical guidelines for magnetic resonance imaging (MRI) of the small bowel (SB) in the setting of inflammatory bowel diseases (IBDs) were detailed in a 2017 consensus issued by European Society of Gastrointestinal and Abdominal Radiology (ESGAR) and European Society of Pediatric Radiology (ESPR); however, MRI for no...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50501-9
更新日期:2019-10-01 00:00:00
abstract::The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16580
更新日期:2015-11-16 00:00:00
abstract::Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC II transactivation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40531
更新日期:2017-01-17 00:00:00
abstract::The brain effortlessly recognizes objects even when the visual information belonging to an object is widely separated, as well demonstrated by the Kanizsa-type illusory contours (ICs), in which a contour is perceived despite the fragments of the contour being separated by gaps. Such large-range visual completion has l...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep08346
更新日期:2015-02-10 00:00:00
abstract::In a previous study, we proposed that age-related mitochondrial respiration defects observed in elderly subjects are partially due to age-associated downregulation of nuclear-encoded genes, including serine hydroxymethyltransferase 2 (SHMT2), which is involved in mitochondrial one-carbon (1C) metabolism. This assertio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52372-6
更新日期:2019-11-05 00:00:00
abstract::A relevant part of embolic strokes of undetermined source (ESUS) is assumed to be cardiogenic. As shown previously, certain biomarkers of endothelial pathology are related to atrial fibrillation (AF). In this long-term follow-up study, we aimed to investigate whether these biomarkers are associated with subsequently d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55943-9
更新日期:2019-12-19 00:00:00
abstract::Many remarkable properties of graphene are derived from its large energy window for Dirac-like electronic states and have been explored for applications in electronics and photonics. In addition, strong electron-phonon interaction in graphene has led to efficient photo-thermo energy conversions, which has been harness...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10582
更新日期:2015-06-08 00:00:00
abstract::The application of metabolic phenotyping in clinical and epidemiological studies is limited by a poor understanding of inter-individual, intra-individual and temporal variability in metabolic phenotypes. Using 1H NMR spectroscopy we characterised short-term variability in urinary metabolites measured from 20 children ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46082
更新日期:2017-04-19 00:00:00
abstract::Stem cell research has yielded promising advances in regenerative medicine, but standard assays generally lack the ability to combine different cell stimulations with rapid sample processing and precise fluid control. In this work, we describe the design and fabrication of a micro-scale cell stimulator capable of simu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11800
更新日期:2015-07-02 00:00:00
abstract::Radiotherapy (RT) is one of the most frequently used methods for cancer treatment. Despite remarkable advancements in RT techniquesthe treatment of radioresistant tumours (i.e. high-grade gliomas) is not yet satisfactory. Finding novel approaches less damaging for normal tissues is of utmost importance. This would mak...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70371-w
更新日期:2020-08-11 00:00:00
abstract::A major issue in human olfaction research is to characterize the main dimensions that organize the space of odors. The present study examines this question and shows that, beside pleasantness, trigeminal sensations, and particularly irritation, play an important role. These results were consistent along two different ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26510-5
更新日期:2018-05-31 00:00:00
abstract::Many species can successfully colonize new areas despite their propagules having low genetic variation. We assessed whether the decreased genetic diversity could result in temporal fluctuations of genetic parameters of the new populations of an invasive species, western flower thrips, Frankliniella occidentalis, using...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11877
更新日期:2015-07-03 00:00:00
abstract::Acoustic structure quantification (ASQ) is a recently developed technique widely used for detecting liver fibrosis. Ultrasound Nakagami parametric imaging based on the Nakagami distribution has been widely used to model echo amplitude distribution for tissue characterization. We explored the feasibility of using ultra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33075
更新日期:2016-09-08 00:00:00
abstract::Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06180
更新日期:2014-08-26 00:00:00
abstract::Both chronic calorie restriction (CCR) and intermittent calorie restriction (ICR) have shown anticancer effects. However, the direct evidence comparing ICR to CCR with respect to cancer prevention is controversial and inconclusive. PubMed and Web of Science were searched on November 25, 2015. The relative risk (RR) [9...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33739
更新日期:2016-09-22 00:00:00
abstract::The genetic data of 17 Y chromosome short tandem repeats in 146 unrelated donor residents in the provinces of Granada, Málaga, and Almería (GMA) were analyzed to determine the genetic legacy of the male inhabitants of the former Kingdom of Granada. A total of 139 unique haplotypes were identified. Observed allele freq...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41580-9
更新日期:2019-03-26 00:00:00
abstract::Breast cancer is a heterogeneous disease with differences in its clinical, molecular and biological features. Traditionally, immunohistochemical markers together with clinicopathologic parameters are used to classify breast cancer and to predict disease outcome. Triple-negative breast cancer (TNBC) is a particular typ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44414
更新日期:2017-03-15 00:00:00
abstract::Neovascularization of the erectile tissue emerges as a beneficial curative approach to treat erectile dysfunction (ED). Here we for the first time report the unexpected role of vasohibin-1 (VASH1), mainly known as an anti-angiogenic factor, in restoring erectile function in diabetic mice. A diabetic patient has lower ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80925-7
更新日期:2021-01-13 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-23597-8
更新日期:2018-04-11 00:00:00
abstract::Iron (Fe) and manganese (Mn) are essential metals which, when scarce in the growth medium, are respectively taken up by the root high affinity transporters IRT1 and NRAMP1 in Arabidopsis thaliana. The molecular bases for low affinity transport however remained unknown. Since IRT1 and NRAMP1 have a broad range of subst...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37222
更新日期:2016-11-16 00:00:00
abstract::Nano-scale investigations of bainitic structures formed at temperatures below 350 °C have shown that the bainitic ferrite lattice is super-saturated in carbon. A high density of intrinsic defects would be playing a part in the carbon-supersaturation levels detected. In this work, the role of C-vacancy complexes on car...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57469-x
更新日期:2020-01-16 00:00:00
abstract::Peripheral artery disease (PAD) is a major cause of acute and chronic illness, with extremely poor prognosis that remains underdiagnosed and undertreated. Trimethylamine-N-Oxide (TMAO), a gut derived metabolite, has been associated with atherosclerotic burden. We determined plasma levels of TMAO by mass spectrometry a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52082-z
更新日期:2019-10-30 00:00:00
abstract::Dysfunctional epicardial adipose tissue (EAT) secretome can influence the heart's stretch response. However, the molecular mechanisms are still poorly understood. The aim of this study was to clarify how dysfunctional EAT promotes maladaptive heart remodeling in cardiovascular disease (CVD) through ST2 production asso...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46676-w
更新日期:2019-07-17 00:00:00
abstract::Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07549-2
更新日期:2017-08-04 00:00:00
abstract::Core-shell Nb2O5/TiO2 composite with hierarchical heterostructure is successfully synthesized In-situ by a facile template-free and acid-free solvothermal method based on the mechanism of liquid phase epitaxy. The chemical circumstance change induced by the alcoholysis of NbCl5 is utilized tactically to trigger core-s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25260
更新日期:2016-04-28 00:00:00
abstract::Facial beauty and moral beauty have been suggested to be two significant forms of social aesthetics. However, it remains unknown the extent to which there are neural underpinnings of the integration of these two forms of beauty. In the present study, participants were asked to make general aesthetic judgments of facia...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38553-3
更新日期:2019-02-13 00:00:00
abstract::Ultrasound-enhanced drug delivery has shown great promise in providing targeted burst release of drug at the site of the disease. Yet current solid ultrasound-responsive particles are non-degradable with limited potential for drug-loading. Here, we report on an ultrasound-responsive multi-cavity poly(lactic-co-glycoli...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46022-0
更新日期:2019-07-03 00:00:00
abstract::Circadian clocks are endogenous oscillators driving daily rhythms in physiology. The cell-autonomous clock is governed by an interlocked network of transcriptional feedback loops. Hundreds of clock-controlled genes (CCGs) regulate tissue specific functions. Transcriptome studies reveal that different organs (e.g. live...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05782
更新日期:2014-07-22 00:00:00
abstract::Most organisms are able to maintain systemic water homeostasis over a wide range of external or dietary osmolarities. The excretory system, composed of the kidneys in mammals and the Malpighian tubules and hindgut in insects, can increase water conservation and absorption to maintain systemic water homeostasis, which ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07993
更新日期:2015-01-23 00:00:00