Markers of endothelial pathology to support detection of atrial fibrillation in embolic stroke of undetermined source.

abstract：:In this study, we developed a novel poly (lactic-co-glycolic acid)-dextran (PLD)-based nanodelivery system to enhance the anticancer potential of cisplatin (CDDP) in osteosarcoma cells. A nanosized CDDP-loaded PLGA-DX nanoparticle (PLD/CDDP) controlled the release rate of CDDP up to 48 h. In vitro cytotoxicity assay s...

journal_title：Scientific reports

authors： Liu P,Sun L,Zhou DS,Zhang P,Wang YH,Li D,Li QH,Feng RJ

更新日期：2015-12-01 00:00:00

abstract：:Willow (Salix spp.) seeds are able to tolerate desiccation, but differ from typical orthodox seeds in that they lose viability in a few days at room temperature, and in that the chloroplasts in embryo tissues do not dedifferentiate during maturation drying, thus retaining chlorophyll and maintaining intact their thyla...

journal_title：Scientific reports

authors： López-Fernández MP,Moyano L,Correa MD,Vasile F,Burrieza HP,Maldonado S

更新日期：2018-11-21 00:00:00

abstract：:Activation of short-chain free fatty acid receptors 3 (FFAR3) has been suggested to promote sympathetic outflow in postganglionic sympathetic neurons or hamper it by a negative coupling to N-type calcium (CaV2.2) channels. Heterogeneity of FFAR3 expression in sympathetic neurons, however, renders single neurons studie...

journal_title：Scientific reports

authors： Colina C,Puhl HL 3rd,Ikeda SR

更新日期：2018-11-26 00:00:00

abstract：:A new, efficient method based on a series of matrices is introduced to completely describe the detailed topology of individual domains and their topology evolution in three-dimensional cellular structures. With this approach, we found a lot of new topological grain forms which are never reported before, i.e., there ar...

journal_title：Scientific reports

authors： Xue W,Wang H,Liu G,Meng L,Xiang S,Ma G,Li W

更新日期：2016-05-10 00:00:00

abstract：:The heterogeneity of metabolic reactions leads to a non-uniform distribution of temperature in different parts of the living cell. The demand to study normal functioning and pathological abnormalities of cellular processes requires the development of new visualization methods. Previously, we have shown that the 35-kDa...

journal_title：Scientific reports

authors： Maksimov EG,Yaroshevich IA,Tsoraev GV,Sluchanko NN,Slutskaya EA,Shamborant OG,Bobik TV,Friedrich T,Stepanov AV

更新日期：2019-06-20 00:00:00

abstract：:In this study, we examined the possible mechanisms of trehalose (Tre) in improving copper-stress (Cu-stress) tolerance in rice seedlings. Our findings indicated that pretreatment of rice seedlings with Tre enhanced the endogenous Tre level and significantly mitigated the toxic effects of excessive Cu on photosynthesis...

journal_title：Scientific reports

authors： Mostofa MG,Hossain MA,Fujita M,Tran LS

更新日期：2015-06-15 00:00:00

abstract：:Methylacetoin (3-hydroxy-3-methylbutan-2-one) and 2-methyl-2,3-butanediol are currently obtained exclusively via chemical synthesis. Here, we report, to the best of our knowledge, the first alternative route, using engineered Escherichia coli. The biological synthesis of methylacetoin was first accomplished by reversi...

journal_title：Scientific reports

authors： Jiang X,Zhang H,Yang J,Zheng Y,Feng D,Liu W,Xu X,Cao Y,Zou H,Zhang R,Cheng T,Jiao F,Xian M

更新日期：2013-01-01 00:00:00

abstract：:The transport of small amounts of liquids on solid surfaces is fundamental for microfluidics applications. Technologies allowing control of droplets of liquid on flat surfaces generally involve the generation of a wettability contrast. This approach is however limited by the resistance to motion caused by the direct c...

journal_title：Scientific reports

authors： Launay G,Sadullah MS,McHale G,Ledesma-Aguilar R,Kusumaatmaja H,Wells GG

更新日期：2020-09-11 00:00:00

abstract：:We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates. The fabricated SCD-MEAs are systematically employed for the in vitro simultaneous amperometric detection of the secretory activity from populations...

journal_title：Scientific reports

authors： Picollo F,Battiato A,Bernardi E,Plaitano M,Franchino C,Gosso S,Pasquarelli A,Carbone E,Olivero P,Carabelli V

更新日期：2016-02-09 00:00:00

abstract：:DNA-directed RNA polymerase II (pol II) is composed of ten core and two dissociable subunits. The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and Rpb7/Polr2g, which are encoded by RPB4/polr2d and RPB7/polr2g genes, respectively. Functional studies of Rpb4/Polr2d in yeast have revealed that Rpb4 plays a role...

journal_title：Scientific reports

authors： Maeta M,Kataoka M,Nishiya Y,Ogino K,Kashima M,Hirata H

更新日期：2020-08-06 00:00:00

abstract：:The individual impact of North Atlantic and Pacific Ocean Western Boundary Currents (OWBCs) on the tropospheric circulation has recently been studied in depth. However, their simultaneous role in shaping the hemisphere-scale wintertime troposphere/stratosphere-coupled circulation and its variability have not been cons...

journal_title：Scientific reports

authors： Omrani NE,Ogawa F,Nakamura H,Keenlyside N,Lubis SW,Matthes K

更新日期：2019-02-28 00:00:00

abstract：:Mosquito surveillance is a fundamental component of planning and evaluating vector control programmes. However, logistical and cost barriers can hinder the implementation of surveillance, particularly in vector-borne disease-endemic areas and in outbreak scenarios in remote areas where the need is often most urgent. T...

journal_title：Scientific reports

authors： Hoshi T,Brugman VA,Sato S,Ant T,Tojo B,Masuda G,Kaneko S,Moji K,Medlock JM,Logan JG

更新日期：2019-08-06 00:00:00

abstract：:Nanodiamond (ND) has emerged as a promising carbon nanomaterial for therapeutic applications. In previous studies, ND has been reported to have outstanding biocompatibility and high uptake rate in various cell types. ND containing nitrogen-vacancy centers exhibit fluorescence property is called fluorescent nanodiamond...

journal_title：Scientific reports

authors： Huang YA,Kao CW,Liu KK,Huang HS,Chiang MH,Soo CR,Chang HC,Chiu TW,Chao JI,Hwang E

更新日期：2014-11-05 00:00:00

abstract：:Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diu...

journal_title：Scientific reports

authors： Araujo MDS,Guo F,Rosbash M

更新日期：2020-03-19 00:00:00

abstract：:Learning to successfully navigate social environments is a critical developmental goal, predictive of long-term wellbeing. However, little is known about how people learn to adjust to different social environments, and how this behaviour emerges across development. Here, we use a series of economic games to assess how...

journal_title：Scientific reports

authors： Westhoff B,Molleman L,Viding E,van den Bos W,van Duijvenvoorde ACK

更新日期：2020-12-10 00:00:00

abstract：:Glutamate (Glu), the key excitatory neurotransmitter in the central nervous system, is considered essential for brain functioning and has a vital role in learning and memory formation. Earlier it was considered as a harmful agent but later found to be useful for many body functions. However, studies regarding the effe...

journal_title：Scientific reports

authors： Tabassum S,Ahmad S,Madiha S,Shahzad S,Batool Z,Sadir S,Haider S

更新日期：2020-07-08 00:00:00

abstract：:A physically active lifestyle is associated with better health in body and mind, and it is urgent that supporting agents for such lifestyles be developed. In rodents, voluntary locomotor activity as an active physical behavior may be mediated by dopaminergic neurons (DNs). Thiamine phosphate esters can stimulate DNs, ...

journal_title：Scientific reports

authors： Saiki M,Matsui T,Soya M,Kashibe T,Shima T,Shimizu T,Naruto T,Kitayoshi T,Akimoto K,Ninomiya S,Soya H

更新日期：2018-07-11 00:00:00

abstract：:The health effects of the endocrine disruptor Bisphenol A (BPA) led to its partial replacement with Bisphenol S (BPS) in several products including food containers, toys, and thermal paper receipts. The acute effects of BPS on myocardial contractility are unknown. We perfused mouse hearts from both sexes for 15 min wi...

journal_title：Scientific reports

authors： Ferguson M,Lorenzen-Schmidt I,Pyle WG

更新日期：2019-11-04 00:00:00

abstract：:Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids (FFA) are essentially unknown, we determined the lipidomic expression profile after burn in correlation to cl...

journal_title：Scientific reports

authors： Qi P,Abdullahi A,Stanojcic M,Patsouris D,Jeschke MG

更新日期：2016-12-16 00:00:00

abstract：:Dengue virus (DENV) infects 400 million people worldwide annually. Infection of more than one serotype of DENV highly corresponds to dengue hemorrhagic fever and dengue shock syndrome, which are the leading causes of high mortality. Due to lack of effective vaccines and unavailable therapies against DENV, discovery of...

journal_title：Scientific reports

authors： Yu JS,Wu YH,Tseng CK,Lin CK,Hsu YC,Chen YH,Lee JC

更新日期：2017-03-24 00:00:00

abstract：:Some 1,3-diarylureas and 1-((1,4-trans)-4-aryloxycyclohexyl)-3-arylureas (cHAUs) activate heme-regulated kinase causing protein synthesis inhibition via phosphorylation of the eukaryotic translation initiation factor 2 (eIF2) in mammalian cancer cells. To evaluate if these agents have potential to inhibit trypanosome ...

journal_title：Scientific reports

authors： Machado FC,Franco CH,Dos Santos Neto JV,Dias-Teixeira KL,Moraes CB,Lopes UG,Aktas BH,Schenkman S

更新日期：2018-03-20 00:00:00

abstract：:Finding strategies to preserve quantum resources in open systems is nowadays a main requirement for reliable quantum-enhanced technologies. We address this issue by considering structured cavities embedding qubits driven by a control technique known as frequency modulation. We first study a single qubit in a lossy cav...

journal_title：Scientific reports

authors： Mortezapour A,Lo Franco R

更新日期：2018-09-24 00:00:00

abstract：:Designer nucleases, like zinc-finger nucleases (ZFNs), represent valuable tools for targeted genome editing. Here, we took advantage of the gamma-retroviral life cycle and produced vectors to transfer ZFNs in the form of protein, mRNA and episomal DNA. Transfer efficacy and ZFN activity were assessed in quantitative p...

journal_title：Scientific reports

authors： Bobis-Wozowicz S,Galla M,Alzubi J,Kuehle J,Baum C,Schambach A,Cathomen T

更新日期：2014-04-11 00:00:00

abstract：:The ability to generate germ cells from pluripotent stem cells (PSCs) is valuable for human regenerative medicine and animal breeding. Germ cell-like cells (GCLCs) have been differentiated from mouse and human PSCs, but not from porcine PSCs, which are considered an ideal model for stem cell applications. Here, we dev...

journal_title：Scientific reports

authors： Wang H,Xiang J,Zhang W,Li J,Wei Q,Zhong L,Ouyang H,Han J

更新日期：2016-06-06 00:00:00

abstract：:Canadian Indigenous peoples (First Nations and Inuit) exhibit a high burden of infectious diseases including tuberculosis influenced by societal factors, and biological determinants. Toll-like receptor (TLR)-mediated innate immune responses are the first line of defence against infections. We examined the production o...

journal_title：Scientific reports

authors： Semple C,Choi KG,Kroeker A,Denechezhe L,Orr P,Mookherjee N,Larcombe L

更新日期：2019-10-02 00:00:00

abstract：:Time-encoding MRI is a single-scan method that uses traditional k-encoding only in one direction. In the orthogonal "time-encoding" direction, a string of echoes appears in an order that depends on the position of the corresponding spin packets. In one variant of time-encoding, this is achieved by using a series of se...

journal_title：Scientific reports

authors： Marhabaie S,Bodenhausen G,Pelupessy P

更新日期：2018-07-18 00:00:00

abstract：:InGaN light emitting diodes (LED) structure with an embedded 1/4λ-stack nanoporous-GaN/undoped-GaN distributed Bragg reflectors (DBR) structure have been demonstrated. Si-heavily doped GaN epitaxial layers (n(+)-GaN) in the 12-period n(+)-GaN/u-GaN stack structure are transformed into low refractive index nanoporous G...

journal_title：Scientific reports

authors： Shiu GY,Chen KT,Fan FH,Huang KP,Hsu WJ,Dai JJ,Lai CF,Lin CF

更新日期：2016-07-01 00:00:00

abstract：:Interaction between polycyclic aromatic hydrocarbon (PAH) molecule and energetic ion is a subject of interest in different areas of modern physics. Here, we present measurements of energy and angular distributions of absolute double differential electron emission cross section for coronene (C24H12) and fluorene (C13H1...

journal_title：Scientific reports

authors： Biswas S,Champion C,Weck PF,Tribedi LC

更新日期：2017-07-17 00:00:00

abstract：:In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...

journal_title：Scientific reports

authors： Royintarat T,Choi EH,Boonyawan D,Seesuriyachan P,Wattanutchariya W

更新日期：2020-01-31 00:00:00

abstract：:People with ataxia-telangiectasia (A-T) display phenotypic variability with regard to progression of immunodeficiency, sino-pulmonary disease, and neurologic decline. To determine the association between differential gene expression, epigenetic state, and phenotypic variation among people with A-T, we performed transc...

journal_title：Scientific reports

authors： McGrath-Morrow SA,Ndeh R,Helmin KA,Khuder B,Rothblum-Oviatt C,Collaco JM,Wright J,Reyfman PA,Lederman HM,Singer BD

更新日期：2020-05-04 00:00:00