Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery.

abstract：:We found that the most suitable flooding disturbance model for regenerating Populus euphratica forest was two to three times per year with a duration of 15-20 days and an intensity of 25-30 m(3)/s. The flooding should take place during the seed emergence to young tree growth stages, and should be based on flooding exp...

journal_title：Scientific reports

authors： Ling H,Zhang P,Xu H,Zhao X

更新日期：2015-10-20 00:00:00

abstract：:Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for comparisons of clinical parameters in...

journal_title：Scientific reports

authors： Joshita S,Umemura T,Usami Y,Yamashita Y,Norman GL,Sugiura A,Yamazaki T,Fujimori N,Kimura T,Matsumoto A,Igarashi K,Yoshizawa K,Ota M,Tanaka E

更新日期：2018-05-25 00:00:00

abstract：:Rice stripe virus-infected females of the small brown planthopper (SBPH, Laodelphax striatellus) usually lay fewer eggs with a longer hatch period, low hatchability, malformation and retarded or defective development compared with healthy females. To explore the molecular mechanism of those phenomena, we analyzed the ...

journal_title：Scientific reports

authors： Liu B,Qin F,Liu W,Wang X

更新日期：2016-06-09 00:00:00

abstract：:Cooperation in one-shot anonymous interactions is a widely documented aspect of human behaviour. Here we shed light on the motivations behind this behaviour by experimentally exploring cooperation in a one-shot continuous-strategy Prisoner's Dilemma (i.e. one-shot two-player Public Goods Game). We examine the distribu...

journal_title：Scientific reports

authors： Capraro V,Jordan JJ,Rand DG

更新日期：2014-10-28 00:00:00

abstract：:Lateral organ boundaries domain (LBD) proteins are plant-specific transcription factors that play a crucial role in growth and development, as well as metabolic processes. However, knowledge of the function of LBD proteins in Camellia sinensis is limited, and no systematic investigations of the LBD family have been re...

journal_title：Scientific reports

authors： Zhang X,He Y,He W,Su H,Wang Y,Hong G,Xu P

更新日期：2019-10-30 00:00:00

abstract：:Kelp forests are in decline globally and large-scale intervention could be required to halt the loss of these valuable ecosystems. To date kelp forest restoration has had limited success and been expensive and unable to address the increasing scale of ecosystem deterioration. Here we developed and tested a new approac...

journal_title：Scientific reports

authors： Fredriksen S,Filbee-Dexter K,Norderhaug KM,Steen H,Bodvin T,Coleman MA,Moy F,Wernberg T

更新日期：2020-03-04 00:00:00

abstract：:No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women's Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake...

journal_title：Scientific reports

authors： Wu QJ,Yang G,Zheng W,Li HL,Gao J,Wang J,Gao YT,Shu XO,Xiang YB

更新日期：2015-05-19 00:00:00

abstract：:Anatase TiO2 is a typical photocatalyst, and its excellent performance is limited in ultraviolet light range due to its wide band gap of 3.2 eV. A series of Se-doped TiO2 nanoparticles in anatase structure with various Se concentrations up to 17.1 at.% were prepared using sol-gel method. The doped Se ions are confirme...

journal_title：Scientific reports

authors： Xie W,Li R,Xu Q

更新日期：2018-06-08 00:00:00

abstract：:Knowing the distribution of marine animals is central to understanding climatic and other environmental influences on population ecology. This information has proven difficult to gain through capture-based methods biased by capture location. Here we show that marine location can be inferred from animal tissues. As the...

journal_title：Scientific reports

authors： MacKenzie KM,Palmer MR,Moore A,Ibbotson AT,Beaumont WR,Poulter DJ,Trueman CN

更新日期：2011-01-01 00:00:00

abstract：:AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex ligand, C8, to HeLa can...

journal_title：Scientific reports

authors： Carvalho J,Paiva A,Cabral Campello MP,Paulo A,Mergny JL,Salgado GF,Queiroz JA,Cruz C

更新日期：2019-05-28 00:00:00

abstract：:Correlating data from different microscopy techniques holds the potential to discover new facets of signaling events in cellular biology. Here we report for the first time a hardware set-up capable of achieving simultaneous co-localized imaging of spatially correlated far-field super-resolution fluorescence microscopy...

journal_title：Scientific reports

authors： Gómez-Varela AI,Stamov DR,Miranda A,Alves R,Barata-Antunes C,Dambournet D,Drubin DG,Paiva S,De Beule PAA

更新日期：2020-01-24 00:00:00

abstract：:Cardiorenal syndrome is defined by primary heart failure conditions influencing or leading to renal injury or dysfunction. Dilated cardiomyopathy (DCM) is a major co-existing form of heart failure (HF) with renal diseases. Myocardin (MYOCD), a cardiac-specific co-activator of serum response factor (SRF), is increased ...

journal_title：Scientific reports

authors： Mittal A,Rana S,Sharma R,Kumar A,Prasad R,Raut SK,Sarkar S,Saikia UN,Bahl A,Dhandapany PS,Khullar M

更新日期：2019-04-10 00:00:00

abstract：:Mitochondrial dysfunction and significant changes in metabolic pathways accompany cancer development and are responsible for maintaining the tumor microenvironment. Normal mitochondria can trigger intrinsic apoptosis by releasing cytochrome c into the cytosol. The survival of malignant cells highly depends on the supp...

journal_title：Scientific reports

authors： Bencze G,Bencze S,Rivera KD,Watson JD,Hidvegi M,Orfi L,Tonks NK,Pappin DJ

更新日期：2020-08-25 00:00:00

abstract：:Small for gestational age (SGA) newborns are often born from hypertensive pregnancies. This study aimed to compare the systemic metabolism of cortisol (F) in pregnancies with SGA and appropriate for gestational age (AGA) infants, considering both the normotensive (NT) and hypertensive patients. We hypothesized that th...

journal_title：Scientific reports

authors： Siemiątkowska A,Kosicka K,Szpera-Goździewicz A,Krzyścin M,Bręborowicz GH,Główka FK

更新日期：2019-11-29 00:00:00

abstract：:Antigens from Mycobacterium tuberculosis (M.tb), have been shown to stimulate human B cell responses to unrelated recall antigens in vitro. However, it is not known whether natural M.tb infection or whether vaccination with, Mycobacterium bovis BCG, has a similar effect. This study investigated the effects of M.tb inf...

journal_title：Scientific reports

authors： Kimuda SG,Andia-Biraro I,Sebina I,Egesa M,Nalwoga A,Smith SG,Bagaya BS,Levin J,Elliott AM,Raynes JG,Cose S

更新日期：2020-08-31 00:00:00

abstract：:Ongoing studies of a multiple track-bearing horizons from massive excavations in the Jinju Formation (Lower Cretaceous) of South Korea have yielded a remarkable diversity of avian, non-avian dinosaur, pterosaur, crocodilian and mammal tracks, many very small and well preserved. Here we report diminutive, didactyl trac...

journal_title：Scientific reports

authors： Kim KS,Lim JD,Lockley MG,Xing L,Kim DH,Piñuela L,Romilio A,Yoo JS,Kim JH,Ahn J

更新日期：2018-11-15 00:00:00

abstract：:Rubber-filler composites are a key component in the manufacture of tyres. The filler provides mechanical reinforcement and additional wear resistance to the rubber, but it in turn introduces non-linear mechanical behaviour to the material which most likely arises from interactions between the filler particles, mediate...

journal_title：Scientific reports

authors： Staniewicz L,Vaudey T,Degrandcourt C,Couty M,Gaboriaud F,Midgley P

更新日期：2014-12-09 00:00:00

abstract：:Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propo...

journal_title：Scientific reports

authors： Yoon C,Kang M,Hong JH,Yang TD,Xing J,Yoo H,Choi Y,Choi W

更新日期：2017-07-26 00:00:00

abstract：:It is challenging to create artificial catalysts that approach enzymes with regard to catalytic efficiency and selectivity. The enantioselective catalysis ranks the privileged characteristic of enzymatic transformations. Here, we report two pyridine-linked bis(β-cyclodextrin) (bisCD) copper(II) complexes that enantios...

journal_title：Scientific reports

authors： Xue SS,Zhao M,Ke ZF,Cheng BC,Su H,Cao Q,Cao ZK,Wang J,Ji LN,Mao ZW

更新日期：2016-02-26 00:00:00

abstract：:Human and animal infections of Enterocytozoon bieneusi (E. bieneusi) have consistently been reported worldwide, garnering public attention; however, the molecular epidemiology of E. bieneusi in the giant panda remains limited. We surveyed captive giant pandas in China for the presence of E. bieneusi by using PCR and s...

journal_title：Scientific reports

authors： Li W,Zhong Z,Song Y,Gong C,Deng L,Cao Y,Zhou Z,Cao X,Tian Y,Li H,Feng F,Zhang Y,Wang C,Li C,Yang H,Huang X,Fu H,Geng Y,Ren Z,Wu K,Peng G

更新日期：2018-04-26 00:00:00

abstract：:Cenozoic climate cooling at the advent of the Eocene-Oligocene transition (EOT), ~33.7 Ma ago, was stamped in the ocean by a series of climatic events albeit the impact of this global climatic transition on terrestrial environments is still fragmentary. Yet archival constraints on Late Eocene atmospheric circulation a...

journal_title：Scientific reports

authors： Sorrel P,Eymard I,Leloup PH,Maheo G,Olivier N,Sterb M,Gourbet L,Wang G,Jing W,Lu H,Li H,Yadong X,Zhang K,Cao K,Chevalier ML,Replumaz A

更新日期：2017-08-10 00:00:00

abstract：:Systemic antioxidative status has been implicated in glaucoma pathogenesis. Additionally, corneal hysteresis (CH) may contribute to glaucoma progression. Here, we evaluated the relationship between biological antioxidant potential (BAP) and CH. This study included 103 patients with open-angle glaucoma (OAG). We used a...

journal_title：Scientific reports

authors： Uchida K,Himori N,Hashimoto K,Shiga Y,Tsuda S,Omodaka K,Nakazawa T

更新日期：2020-01-17 00:00:00

abstract：:The paper presents the procedure for planning an experiment to create standard sets of reagents for a technetium-99m generator based on glucose derivatives. All stages are presented from researching the required quantities of a substance, a reducing agent, a stabilizer and auxiliary components to developing lyophilize...

journal_title：Scientific reports

authors： Stasyuk E,Sкuridin V,Rogov A,Zelchan R,Sadkin V,Varlamova N,Nestеrov E

更新日期：2020-03-20 00:00:00

abstract：:Tolerance to Dutch elm disease (DED) has been linked to the rapid and/or high induction of disease-responsive genes after infection with the fungus Ophiostoma novo-ulmi. Although the fungal infection by O. novo-ulmi primarily takes places in xylem vessels, it is still unclear how xylem contributes to the defense again...

journal_title：Scientific reports

authors： Sherif SM,Erland LA,Shukla MR,Saxena PK

更新日期：2017-08-02 00:00:00

abstract：:Given new distribution patterns of the endangered North Atlantic right whale (NARW; Eubalaena glacialis) population in recent years, an improved understanding of spatio-temporal movements are imperative for the conservation of this species. While so far visual data have provided most information on NARW movements, pas...

journal_title：Scientific reports

authors： Davis GE,Baumgartner MF,Bonnell JM,Bell J,Berchok C,Bort Thornton J,Brault S,Buchanan G,Charif RA,Cholewiak D,Clark CW,Corkeron P,Delarue J,Dudzinski K,Hatch L,Hildebrand J,Hodge L,Klinck H,Kraus S,Martin B,Mellin

更新日期：2017-10-18 00:00:00

abstract：:M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP inhibits HIV-1 virio...

journal_title：Scientific reports

authors： Wang Q,Zhang X,Han Y,Wang X,Gao G

更新日期：2016-09-08 00:00:00

abstract：:Family studies have identified a heritable component to self-harm that is partially independent from comorbid psychiatric disorders. However, the genetic aetiology of broad sense (non-suicidal and suicidal) self-harm has not been characterised on the molecular level. In addition, controversy exists about the degree to...

journal_title：Scientific reports

authors： Campos AI,Verweij KJH,Statham DJ,Madden PAF,Maciejewski DF,Davis KAS,John A,Hotopf M,Heath AC,Martin NG,Rentería ME

更新日期：2020-06-16 00:00:00

abstract：:Seed size is a major determinant of seed yield but few is known about the genetics controlling of seed size in plants. Phytohormones cytokinin and brassinosteroid were known to be involved in the regulation of herbaceous plant seed development. Here we identified a homolog of Auxin Response Factor 19 (JcARF19) from a ...

journal_title：Scientific reports

authors： Sun Y,Wang C,Wang N,Jiang X,Mao H,Zhu C,Wen F,Wang X,Lu Z,Yue G,Xu Z,Ye J

更新日期：2017-01-19 00:00:00

abstract：:Novel glasses in a Ga2S3-Sb2S3-AgI system were prepared with a melt-quenching method, and their glass-forming region was identified. The maximum dissolvable AgI in glasses was 65 mol%. The thermal, optical, and structural properties of glasses were investigated as a function of AgI and Ga2S3 contents. The Ga2S3-Sb2S3-...

journal_title：Scientific reports

authors： Huang X,Jiao Q,Lin C,Ma H,Zhang X,Zhu E,Liu X,Dai S,Xu T

更新日期：2018-01-26 00:00:00

abstract：:Models of exchange-bias in thin films have been able to describe various aspects of this technologically relevant effect. Through appropriate choices of free parameters the modelled hysteresis loops adequately match experiment, and typical domain structures can be simulated. However, the use of these parameters, notab...

journal_title：Scientific reports

authors： Benassi A,Marioni MA,Passerone D,Hug HJ

更新日期：2014-03-28 00:00:00