Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells.

abstract：:To investigate the role of the altered activation of the immune system in the prognosis of patients affected by laryngeal squamous cell carcinoma (LSCC). We analyzed 56 patients with advanced LSCC divided into two groups according to their prognosis: the first group relapsed within 24 months after treatment, the secon...

journal_title：Scientific reports

authors： Tagliabue M,Maffini F,Fumagalli C,Gandini S,Lepanto D,Corso F,Cacciola S,Ranghiero A,Rappa A,Vacirca D,Cossu Rocca M,Alterio D,Guerini Rocco E,Cattaneo A,Chu F,Zorzi S,Curigliano G,Chiocca S,Barberis M,Viale G,Ans

更新日期：2020-10-27 00:00:00

abstract：:A novel type of transparent monitor with high-resolution images based on Si-SiO2 core-shell nanoparticles is presented in this contribution. In this monitor, a quasi-array of nanoparticles was used to obtain a very sharp scattering profile. For this purpose, the Si-SiO2 nanoparticles were synthesized and with controll...

journal_title：Scientific reports

authors： Dolatyari M,Jafari A,Rostami A,Klein A

更新日期：2019-02-19 00:00:00

abstract：:The macular ellipsoid zone intensity (mEZi) is a known marker of disease severity in a number of diverse ocular diseases. The purpose of this study was to establish an automated method (AM) for mEZi quantification and to compare the method's performance with that of a manual method (MM) for glaucoma patients and healt...

journal_title：Scientific reports

authors： Ha A,Sun S,Kim YK,Jeoung JW,Kim HC,Park KH

更新日期：2019-12-24 00:00:00

abstract：:In this work, cerium-diethyldithiocarbamate (Ce-DEDTC) complex was synthesized as a novel anti-corrosion pigment. The structure of the synthesized pigment was characterized by employing Fourier transfer infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, inductively coupled plasma optical emission sp...

journal_title：Scientific reports

authors： Mohammadi I,Shahrabi T,Mahdavian M,Izadi M

更新日期：2020-03-19 00:00:00

abstract：:A novel dinuclear Ir(III) complex 5 was discovered to be specific to G-quadruplex DNA, and was utilized in a label-free G-quadruplex-based detection platform for transcription factor activity. The principle of this assay was demonstrated by using HIF-1α as a model protein. Moreover, this HIF-1α detection assay exhibit...

journal_title：Scientific reports

authors： Lu L,Wang M,Mao Z,Kang TS,Chen XP,Lu JJ,Leung CH,Ma DL

更新日期：2016-03-02 00:00:00

abstract：:Virus production in the deep-sea environment has been found to be high, and viruses have been suggested to play significant roles in the overall functioning of this ecosystem. Nevertheless, little is known about these viruses, including the mechanisms that control their production, which makes them one of the least un...

journal_title：Scientific reports

authors： Jian H,Xiong L,Xu G,Xiao X,Wang F

更新日期：2016-02-22 00:00:00

abstract：:Fluid overload (FO) has been shown to adversely affect multiple organs and survival in critically ill patients. Liver transplantation (LT) carries the risk of massive transfusion, which frequently results in FO. We investigated the association of postoperative weight gain with graft failure, early allograft dysfunctio...

journal_title：Scientific reports

authors： Jeong HW,Jung KW,Kim SO,Kwon HM,Moon YJ,Jun IG,Song JG,Hwang GS

更新日期：2019-12-27 00:00:00

abstract：:It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain, and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells. Haem is enzymatically degraded to iron, carbon monoxide (CO), and ...

journal_title：Scientific reports

authors： Takeda TA,Mu A,Tai TT,Kitajima S,Taketani S

更新日期：2015-05-20 00:00:00

abstract：:Ultrasound-enhanced drug delivery has shown great promise in providing targeted burst release of drug at the site of the disease. Yet current solid ultrasound-responsive particles are non-degradable with limited potential for drug-loading. Here, we report on an ultrasound-responsive multi-cavity poly(lactic-co-glycoli...

journal_title：Scientific reports

authors： Su X,Thomas RG,Bharatula LD,Kwan JJ

更新日期：2019-07-03 00:00:00

abstract：:As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to inhibit gene transcription. As such, BET inhibitors may be useful ...

journal_title：Scientific reports

authors： Gibbons HR,Mi DJ,Farley VM,Esmond T,Kaood MB,Aune TM

更新日期：2019-07-16 00:00:00

abstract：:Omniphobic surfaces with reentrant microstructures have been investigated for a range of applications, but the evaporation of high- and low-surface-tension liquid droplets placed on such surfaces has not been rigorously studied. In this work, we develop a technique to fabricate omniphobic surfaces on copper substrates...

journal_title：Scientific reports

authors： Chen X,Weibel JA,Garimella SV

更新日期：2015-11-25 00:00:00

abstract：:Accounting for about 1.5 million deaths annually, lung cancer is the prevailing cause of cancer deaths worldwide, mostly associated with long-term smoking effects. Numerous small-animal studies are performed currently in order to better understand the pathogenesis of the disease and to develop treatment strategies. Wi...

journal_title：Scientific reports

authors： Scherer K,Yaroshenko A,Bölükbas DA,Gromann LB,Hellbach K,Meinel FG,Braunagel M,Berg JV,Eickelberg O,Reiser MF,Pfeiffer F,Meiners S,Herzen J

更新日期：2017-03-24 00:00:00

abstract：:Mitochondrial DNA (mtDNA) mutations are commonly found in the skeletal muscle of patients with mitochondrial disease, inflammatory myopathies and sarcopenia. The majority of these mutations are mtDNA deletions, which accumulate to high levels in individual muscle fibres causing a respiratory defect. Most mtDNA deletio...

journal_title：Scientific reports

authors： Rygiel KA,Grady JP,Taylor RW,Tuppen HA,Turnbull DM

更新日期：2015-05-19 00:00:00

abstract：:Neuropathic pain is characterized by an uncertain etiology and by a poor response to common therapies. The ineffectiveness and the frequent side effects of the drugs used to counteract neuropathic pain call for the discovery of new therapeutic strategies. Laser therapy proved to be effective for reducing pain sensitiv...

journal_title：Scientific reports

authors： Micheli L,Cialdai F,Pacini A,Branca JJV,Morbidelli L,Ciccone V,Lucarini E,Ghelardini C,Monici M,Di Cesare Mannelli L

更新日期：2019-06-26 00:00:00

abstract：:A key to the success of chimeric antigen receptor (CAR) T-cell based therapies greatly rely on the capacity to identify and target antigens with expression restrained to tumor cells. Here we present a strategy to generate CAR T-cells that are only effective locally (tumor tissue), potentially also increasing the choic...

journal_title：Scientific reports

authors： Juillerat A,Marechal A,Filhol JM,Valogne Y,Valton J,Duclert A,Duchateau P,Poirot L

更新日期：2017-01-20 00:00:00

abstract：:Breast cancer is the most common cancer among women, and its incidence is on a constant rise. Previous studies suggest that higher levels of plasma prolactin are associated with escalated risk of breast cancer, however, these results are contradictory and inconclusive. PubMed and Medline were used to search and identi...

journal_title：Scientific reports

authors： Wang M,Wu X,Chai F,Zhang Y,Jiang J

更新日期：2016-05-17 00:00:00

abstract：:The chemiresistive thin film gas sensors with fast response, high sensitivity, low power consumption and mass-produced potency, have been expected for practical application. It requires both sensitive materials, especially exquisite nanomaterials, and efficient substrate chip for heating and electrical addressing. How...

journal_title：Scientific reports

authors： Dai Z,Xu L,Duan G,Li T,Zhang H,Li Y,Wang Y,Wang Y,Cai W

更新日期：2013-01-01 00:00:00

abstract：:In the human visual system, different attributes of an object, such as shape and color, are separately processed in different modules and then integrated to elicit a specific response. In this process, different attributes are thought to be temporarily "bound" together by focusing attention on the object; however, how...

journal_title：Scientific reports

authors： Ishizaki T,Morita H,Morita M

更新日期：2015-03-12 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:Auricle defects are important and common occurrences in forensic medicine. The accurate measurement and assessment of auricle defects is key to identifying and evaluating injury, and the currently available methods are known to be labor intensive and inaccurate. In this paper, we introduce an identification and docume...

journal_title：Scientific reports

authors： Zhan G,Han L,Li Z,Liu Z,Fu J,Zhong K

更新日期：2018-02-12 00:00:00

abstract：:Disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in blood of breast cancer patients (pts) are known to correlate with worse outcome. Here we demonstrate a different prognostic value of DTCs and CTCs and explain these findings by early clodronate intake. CTCs (n = 376 pts) were...

journal_title：Scientific reports

authors： Kasimir-Bauer S,Reiter K,Aktas B,Bittner AK,Weber S,Keller T,Kimmig R,Hoffmann O

更新日期：2016-05-23 00:00:00

abstract：:Organic solar cells (OSCs) have attracted great attention in the past 30 years, and the power conversion efficiency (PCE) now reaches around 10%, largely owning to the rapid material developments. Meanwhile with the progress in the device performance, more and more interests are turning to understanding the fundamenta...

journal_title：Scientific reports

authors： Li H,He D,Zhou Q,Mao P,Cao J,Ding L,Wang J

更新日期：2017-01-10 00:00:00

abstract：:To appraise the content and pollution level of cadmium (Cd), arsenic (As), mercury (Hg), nickel (Ni) and lead (Pb) in bus stop dusts, representative samples (n = 53) were collected from the city of Qingyang in Gansu province, NW China. The Cd, As, Hg, Ni, and Pb contents and physicochemical properties (particle size, ...

journal_title：Scientific reports

authors： Wu Y,Lu X

更新日期：2018-08-22 00:00:00

abstract：:Much attention has been given in the literature to the effects of astrophysical events on human and land-based life. However, little has been discussed on the resilience of life itself. Here we instead explore the statistics of events that completely sterilise an Earth-like planet with planet radii in the range 0.5-1....

journal_title：Scientific reports

authors： Sloan D,Alves Batista R,Loeb A

更新日期：2017-07-14 00:00:00

abstract：:The colour of oyster shells is a very diverse characteristic morphotype, forming intriguing vivid patterns both on the inside and outside of the shell. In the present study, we have identified for the first time, the presence of several porphyrins as constituents of the shell pigmentation of the Crassostrea gigas oyst...

journal_title：Scientific reports

authors： Bonnard M,Cantel S,Boury B,Parrot I

更新日期：2020-07-22 00:00:00

abstract：:Usher Syndrome (USH) is a rare disease with hearing loss, retinitis pigmentosa and, sometimes, vestibular dysfunction. A phenotype heterogeneity is reported. Recent evidence indicates that USH is likely to belong to an emerging class of sensory ciliopathies. Olfaction has recently been implicated in ciliopathies, but ...

journal_title：Scientific reports

authors： Ribeiro JC,Oliveiros B,Pereira P,António N,Hummel T,Paiva A,Silva ED

更新日期：2016-06-22 00:00:00

abstract：:When one liquid is introduced into another immiscible one, it ultimately fragments due to hydrodynamic instability. In contrast to neck pinch-off without external actuation, the viscous two-fluid system subjected to an oscillatory flow demonstrates higher efficiency in breaking fluid threads. However, the underlying d...

journal_title：Scientific reports

authors： Zhu P,Tang X,Tian Y,Wang L

更新日期：2016-08-11 00:00:00

abstract：:Approximately 75% of melanomas have known driver oncogenic mutations in BRAF, NRAS, GNA11 or GNAQ, while the mutations providing constitutive oncogenic signaling in the remaining melanomas are not known. We established a melanoma cell line from a tumor with none of the common driver mutations. This cell line demonstra...

journal_title：Scientific reports

authors： Atefi M,Titz B,Tsoi J,Avramis E,Le A,Ng C,Lomova A,Lassen A,Friedman M,Chmielowski B,Ribas A,Graeber TG

更新日期：2016-06-08 00:00:00

abstract：:Quality assessment of protein models using no other information than the structure of the model itself has been shown to be useful for structure prediction. Here, we introduce two novel methods, ProQRosFA and ProQRosCen, inspired by the state-of-art method ProQ2, but using a completely different description of a prote...

journal_title：Scientific reports

authors： Uziela K,Shu N,Wallner B,Elofsson A

更新日期：2016-10-04 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Chefaoui RM,Duarte CM,Serrão EA

更新日期：2020-04-03 00:00:00