Controlled electromechanical cell stimulation on-a-chip.

abstract：:Ion mobility mass spectrometry (IM-MS) is a technique capable of investigating structural changes of biomolecules based on their collision cross section (CCS). Recent advances in IM-MS allow us to separate carbohydrate isomers with subtle conformational differences, but the relationship between CCS and atomic structur...

journal_title：Scientific reports

authors： Re S,Watabe S,Nishima W,Muneyuki E,Yamaguchi Y,MacKerell AD Jr,Sugita Y

更新日期：2018-01-26 00:00:00

abstract：:Although various surgical procedures have been developed for chronic rotator cuff tear repair, the re-tear rate remains high with severe fat infiltration. However, little is known about the molecular regulation of this process. Mesenchymal stem cells (MSCs) in the intra-muscular space are origin of ectopic fat cells i...

journal_title：Scientific reports

authors： Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E

更新日期：2018-06-25 00:00:00

abstract：:Changes in the stability, hydrogen diffusion, and mechanical properties of the NbH phases from Ni-doping was studied by using first-principles methods. The calculation results reveal that the single H atom adsorption is energetically favorable at the tetrahedral interstitial site (TIS) and octahedral interstitial site...

journal_title：Scientific reports

authors： Wu Y,Wang Z,Wang D,Wan Z,Zhong Y,Hu C,Zhou H

更新日期：2017-07-26 00:00:00

abstract：:Smart nanoparticles (NPs) that respond to external and internal stimulations have been developing to achieve optimal drug release in tumour. However, applying these smart NPs to attain high antitumour performance is hampered by limited drug carriers and inefficient spatiotemporal control. Here we report a noninvasive ...

journal_title：Scientific reports

authors： Zhao P,Zheng M,Luo Z,Gong P,Gao G,Sheng Z,Zheng C,Ma Y,Cai L

更新日期：2015-09-24 00:00:00

abstract：:Modelling the biokinetics of radionuclide excretion or retention is important in nuclear medicine and following accidental/malicious radioactivity releases. Sums of discrete exponential decay rates are often used, but we hypothesized that continuous probability distributions (CPD) of decay rates can describe the data ...

journal_title：Scientific reports

authors： Shuryak I,Dadachova E

更新日期：2019-02-04 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death worldwide. The use of alpha fetoprotein (AFP) alone was not an accurate biomarker for HCC despite its high specificity. Therefore, we assessed the possible role of serum biomarkers that have been mentioned briefly in previous studie...

journal_title：Scientific reports

authors： N Zekri AR,El Kassas M,Salam ESE,Hassan RM,Mohanad M,Gabr RM,M Lotfy M,Abdel-Zaher RAT,Bahnassy AA,Ahmed OS

更新日期：2020-03-20 00:00:00

abstract：:Polymers have appealing optical, biochemical, and mechanical qualities, including broadband transparency, ease of functionalization, and biocompatibility. However, their low refractive indices have precluded wavelength-scale optical confinement and nanophotonic applications in polymers. Here, we introduce a suspended ...

journal_title：Scientific reports

authors： Gan X,Clevenson H,Tsai CC,Li L,Englund D

更新日期：2013-01-01 00:00:00

abstract：:Volumetric and morphometric studies have demonstrated structural abnormalities related to chronic epilepsies on a cohort- and population-based level. On a single-patient level, specific patterns of atrophy or cortical reorganization may be widespread and heterogeneous but represent potential targets for further person...

journal_title：Scientific reports

authors： Rummel C,Slavova N,Seiler A,Abela E,Hauf M,Burren Y,Weisstanner C,Vulliemoz S,Seeck M,Schindler K,Wiest R

更新日期：2017-09-07 00:00:00

abstract：:The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) has been counted on for conserving threatened marine fish since it regulates the commercial international trade of these species. Implementation of the international treaty for Mantas included on CITES Appendix II is challengin...

journal_title：Scientific reports

authors： Zeng Y,Wu Z,Zhang C,Meng Z,Jiang Z,Zhang J

更新日期：2016-11-23 00:00:00

abstract：:Computer simulation provides an increasingly realistic picture of large-scale conformational change of proteins, but investigations remain fundamentally constrained by the femtosecond timestep of molecular dynamics simulations. For this reason, many biologically interesting questions cannot be addressed using accessib...

journal_title：Scientific reports

authors： Heilmann N,Wolf M,Kozlowska M,Sedghamiz E,Setzler J,Brieg M,Wenzel W

更新日期：2020-10-23 00:00:00

abstract：:Lung adenocarcinoma (LUAD) is characterized by high infiltration and rapid growth. The function of the stem cell population is to control and maintain cell regeneration. Therefore, it is necessary to study the prognostic value of stem cell-related genes in LUAD. Signature genes were screened out from 166 stem cell-rel...

journal_title：Scientific reports

authors： Huang Z,Shi M,Zhou H,Wang J,Zhang HJ,Shi J-

更新日期：2021-01-18 00:00:00

abstract：:Cell fate decisions are controlled by the interplay of transcription factors and epigenetic modifiers, which together determine cellular identity. Here we elaborate on the role of miR302 in the regulation of cell plasticity. Overexpression of miR302 effected silencing of the TGFβ type II receptor and facilitated plast...

journal_title：Scientific reports

authors： De Chiara L,Andrews D,Watson A,Oliviero G,Cagney G,Crean J

更新日期：2017-02-14 00:00:00

abstract：:The aminopeptidase gene from Mesorhizobium SEMIA3007 was cloned and overexpressed in Escherichia coli. The enzyme called MesoAmp exhibited optimum activity at pH 8.5 and 45 °C and was strongly activated by Co2+ and Mn2+. Under these reaction conditions, the enzyme displayed Km and kcat values of 0.2364 ± 0.018 mM and ...

journal_title：Scientific reports

authors： Sierra EM,Pereira MR,Maester TC,Gomes-Pepe ES,Mendoza ER,Lemos EGM

更新日期：2017-09-06 00:00:00

abstract：:With new degrees of freedom to achieve full control of the optical wavefront, metasurfaces could overcome the fabrication embarrassment faced by the metamaterials. In this paper, a broadband hologram using metasurface consisting of elongated nanoapertures array with different orientations has been experimentally demon...

journal_title：Scientific reports

authors： Zhang X,Jin J,Wang Y,Pu M,Li X,Zhao Z,Gao P,Wang C,Luo X

更新日期：2016-01-28 00:00:00

abstract：:Quantification of stillbirth risk has potential to support clinical decision-making. Studies that have attempted to quantify stillbirth risk have been hampered by small event rates, a limited range of predictors that typically exclude obstetric history, lack of validation, and restriction to a single classifier (logis...

journal_title：Scientific reports

authors： Malacova E,Tippaya S,Bailey HD,Chai K,Farrant BM,Gebremedhin AT,Leonard H,Marinovich ML,Nassar N,Phatak A,Raynes-Greenow C,Regan AK,Shand AW,Shepherd CCJ,Srinivasjois R,Tessema GA,Pereira G

更新日期：2020-03-24 00:00:00

abstract：:Knowledge of the direct role humans have had in changing the landscape requires the perspective of historical and archaeological sources, as well as climatic and ecologic processes, when interpreting paleoecological records. People directly impact land at the local scale and land use decisions are strongly influenced ...

journal_title：Scientific reports

authors： Mensing SA,Schoolman EM,Tunno I,Noble PJ,Sagnotti L,Florindo F,Piovesan G

更新日期：2018-02-01 00:00:00

abstract：:The metal-free nitrogen-doped graphitic-carbon@graphene (Ng-C@G) is prepared from a composite of polyaniline and graphene by a facile polymerization following by pyrolysis for electrochemical oxygen reduction reaction (ORR). Pyrolysis creates a sponge-like with ant-cave-architecture in the polyaniline derived nitrogen...

journal_title：Scientific reports

authors： Begum H,Ahmed MS,Kim YB

更新日期：2020-07-24 00:00:00

abstract：:Electrohydrodynamic (EHD) jet printing has a variety of benefits compared to conventional inkjet techniques, such as high resolution and the ability to work with high-viscosity pastes. In this work, Ag nanoparticles with 4000 cPs were chosen because they are printable on various substrates for electronic devices. The ...

journal_title：Scientific reports

authors： Can TTT,Nguyen TC,Choi WS

更新日期：2019-06-24 00:00:00

abstract：:The ability to shape the index profile of optical fibers holds the key to fully flexible engineering of their optical properties and future applications. We present a new approach for the development of a graded index fused silica fiber based on core nanostructurization. A graded index core is obtained by means of dis...

journal_title：Scientific reports

authors： Anuszkiewicz A,Kasztelanic R,Filipkowski A,Stepniewski G,Stefaniuk T,Siwicki B,Pysz D,Klimczak M,Buczynski R

更新日期：2018-08-17 00:00:00

abstract：:Mammalian spermatogenesis is a classic adult stems cell-dependent process, supported by the self-renewal and differentiation of spermatogonial stem cells (SSCs). However, the identification of SSCs and elucidation of their behaviors in undisturbed testis has long been a big challenge. Here, we generated a knock-in mou...

journal_title：Scientific reports

authors： Sun F,Xu Q,Zhao D,Degui Chen C

更新日期：2015-12-01 00:00:00

abstract：:An initial study of processing bioresorbable polycaprolactone (PCL) through material jetting was conducted using a Fujifilm Dimatix DMP-2830 material printer. The aim of this work was to investigate a potential solvent based method of jetting polycaprolactone. Several solvents were used to prepare a PCL solvent based ...

journal_title：Scientific reports

authors： He Y,Wildman RD,Tuck CJ,Christie SD,Edmondson S

更新日期：2016-02-12 00:00:00

abstract：:New ionic liquids with multiple Brönsted acid sites were synthesized in ≥98% yield, and their inhibiting properties for the corrosion of carbon steel in 0.5 M HCl solution had been evaluated using electrochemical impedance spectroscopy, potentiodynamic polarization and weight loss method, finally the possible inhibiti...

journal_title：Scientific reports

authors： Cao S,Liu D,Zhang P,Yang L,Yang P,Lu H,Gui J

更新日期：2017-08-18 00:00:00

abstract：:Hepatocarcinoma (HCC) is one of the deadliest cancers in the world and represents a significant disease burden. Better biomarkers are needed for early detection of HCC. Metabolomics was applied to urine samples obtained from HCC patients to discover noninvasive and reliable biomarkers for rapid diagnosis of HCC. Metab...

journal_title：Scientific reports

authors： Liang Q,Liu H,Wang C,Li B

更新日期：2016-01-25 00:00:00

abstract：:Conversion of lignocellulosic biomass to biofuels and biomaterials suffers from high production costs associated with biomass pretreatment and enzymatic hydrolysis. In-planta expression of lignocellulose-digesting enzymes is a promising approach to reduce these cost elements. However, this approach faces a number of c...

journal_title：Scientific reports

authors： Mir BA,Myburg AA,Mizrachi E,Cowan DA

更新日期：2017-09-13 00:00:00

abstract：:Ocular involvement in leukemia is considered rare. Ocular symptoms can be the presenting signs of leukemia, they can appear after diagnosis has been established, or they can be the first manifestation of a relapse after remission. We report, to the best of our knowledge for the first time, the ocular manifestation of ...

journal_title：Scientific reports

authors： Vishnevskia-Dai V,Sella King S,Lekach R,Fabian ID,Zloto O

更新日期：2020-02-06 00:00:00

abstract：:Enhancement of endogenous neurogenesis after ischemic stroke may improve functional recovery. We previously demonstrated that medium B, which is a combination with epidermal growth factor (EGF) and fibronectin, can promote neural stem/progenitor cell (NSPC) proliferation and migration. Here, we showed that medium B pr...

journal_title：Scientific reports

authors： Chen YA,Tsai YC,Chen YD,Liu DZ,Young TH,Tsai LK

更新日期：2020-04-20 00:00:00

abstract：:Group-IVa elements silicon and germanium are known for their semiconducting properties at room temperature, which are technologically critical. Metallicity and superconductivity are found at higher pressures only, Ge β-tin (tI4) being the first high-pressure metallic phase in the phase diagram. However, recent experim...

journal_title：Scientific reports

authors： Selli D,Baburin IA,Martoňák R,Leoni S

更新日期：2013-01-01 00:00:00

abstract：:In response to infestation by herbivores, rice plants rapidly biosynthesize defense compounds by activating a series of defense-related pathways. However, which defensive compounds in rice are effective against herbivores remains largely unknown. We found that the infestation of white-backed planthopper (WBPH) Sogatel...

journal_title：Scientific reports

authors： Wang W,Yu Z,Meng J,Zhou P,Luo T,Zhang J,Wu J,Lou Y

更新日期：2020-04-01 00:00:00

abstract：:Sufficient tissue oxygenation is required for regular brain function; thus oxygen supply must be tightly regulated to avoid hypoxia and irreversible cell damage. If hypoxia occurs the transcription factor complex hypoxia-inducible factor (HIF) will accumulate and coordinate adaptation of cells to hypoxia. However, eve...

journal_title：Scientific reports

authors： Kleszka K,Leu T,Quinting T,Jastrow H,Pechlivanis S,Fandrey J,Schreiber T

更新日期：2020-11-05 00:00:00

abstract：:In order to clearly understand the intrinsic microwave absorption properties of carbon nanomaterials, we proposed an efficient strategy to synthesize high purity metal-free carbon nanotubes (CNTs) over water-soluble K2CO3 particles through chemical vapor decomposition and water-washing process. The comparison results ...

journal_title：Scientific reports

authors： Qi X,Xu J,Hu Q,Deng Y,Xie R,Jiang Y,Zhong W,Du Y

更新日期：2016-06-21 00:00:00