Dysfunctional EAT thickness may promote maladaptive heart remodeling in CVD patients through the ST2-IL33 system, directly related to EPAC protein expression.

abstract：:Short QT syndrome (SQTS) is a rare condition characterized by abnormally 'short' QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death. This simulation study investigated arrhythmia dynamics in multi-scale human ventricle models associated with the SQT2-related V307L KCNQ1 'gain-...

journal_title：Scientific reports

authors： Adeniran I,Whittaker DG,El Harchi A,Hancox JC,Zhang H

更新日期：2017-08-16 00:00:00

abstract：:Left ventricular mass index (LVMI) increase has been described in hypertension (HTN), but less is known about its association with type 2 diabetes (T2DM). As these conditions frequently co-exist, we investigated the association of T2DM, HTN and both with echocardiographic parameters, and hypothesized that patients wit...

journal_title：Scientific reports

authors： Seferovic JP,Tesic M,Seferovic PM,Lalic K,Jotic A,Biering-Sørensen T,Giga V,Stankovic S,Milic N,Lukic L,Milicic T,Macesic M,Gajovic JS,Lalic NM

更新日期：2018-01-17 00:00:00

abstract：:Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this stud...

journal_title：Scientific reports

authors： Takeuchi H,Taki Y,Nouchi R,Yokoyama R,Nakagawa S,Iizuka K,Sakaki K,Araki T,Nozawa T,Ikeda S,Yokota S,Hanawa S,Magistro D,Kotozaki Y,Sasaki Y,Dos S Kawata KH,Kawashima R

更新日期：2020-07-28 00:00:00

abstract：:Highly Tm(3+) doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm(3+) doped barium gallo-germanate (BGG) glasses....

journal_title：Scientific reports

authors： Wen X,Tang G,Yang Q,Chen X,Qian Q,Zhang Q,Yang Z

更新日期：2016-02-01 00:00:00

abstract：:Plant species of the genus Cecropia (Urticaceae) are used as traditional medicine in Latin-America, and are commercially available as food supplements. The aim of this study was to characterize and compare the phytochemical constituents of four Cecropia species collected in Panama. The structures of 11 compounds isola...

journal_title：Scientific reports

authors： Rivera-Mondragón A,Bijttebier S,Tuenter E,Custers D,Ortíz OO,Pieters L,Caballero-George C,Apers S,Foubert K

更新日期：2019-02-11 00:00:00

abstract：:The spectral distribution of light emitted from a scanning tunnelling microscope junction not only bears its intrinsic plasmonic signature but is also imprinted with the characteristics of optical frequency fluc- tuations of the tunnel current. Experimental spectra from gold-gold tunnel junctions are presented that sh...

journal_title：Scientific reports

authors： Kalathingal V,Dawson P,Mitra J

更新日期：2017-06-14 00:00:00

abstract：:Gyroviruses (GyVs) are small, single-stranded, circular DNA viruses in the genus Gyrovirus, which consists of the chicken anemia virus (CAV) prototype and nine other viral species. These different GyV species have been reported in chickens, humans, mice, and companion animals. To date, CAV has been identified in the f...

journal_title：Scientific reports

authors： Niu JT,Yi SS,Dong GY,Guo YB,Zhao YL,Huang HL,Wang K,Hu GX,Dong H

更新日期：2019-09-16 00:00:00

abstract：:The present work is aimed at studying the dynamic behaviour of the tryptopnanase (tna) operon, which encodes the proteins necessary to uptake and metabolise tryptophan to use it as a carbon source in the absence of glucose. To this end, we designed a micro-bioreactor capable of driving a bacterial culture to a station...

journal_title：Scientific reports

authors： Orozco-Gómez DI,Sosa-Hernández JE,Gallardo-Navarro ÓA,Santana-Solano J,Santillán M

更新日期：2019-04-01 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL, lipocalin 2 or LCN2) is an iron carrier protein whose circulating level is increased by kidney injury, bacterial infection and obesity, but its metabolic consequence remains elusive. To study physiological role of LCN2 in energy homeostasis, we challenged female Lcn2 k...

journal_title：Scientific reports

authors： Ishii A,Katsuura G,Imamaki H,Kimura H,Mori KP,Kuwabara T,Kasahara M,Yokoi H,Ohinata K,Kawanishi T,Tsuchida J,Nakamoto Y,Nakao K,Yanagita M,Mukoyama M,Mori K

更新日期：2017-11-14 00:00:00

abstract：:TBX21 recode T-bet which is an important transcription factor that drives the Th1 immune response primarily by promoting expression of the interferon-gamma (IFNG) gene. Recent studies have shown that genetic variants in TBX21 and IFNG are connected with risk of systemic lupus erythematosus (SLE). The aim of the presen...

journal_title：Scientific reports

authors： Leng RX,Pan HF,Liu J,Yang XK,Zhang C,Tao SS,Wang DG,Li XM,Li XP,Yang W,Ye DQ

更新日期：2016-02-26 00:00:00

abstract：:The spontaneous emission coefficient, Arad, a global molecular property, is one of the most important quantities related to the luminescence of complexes of lanthanide ions. In this work, by suitable algebraic transformations of the matrices involved, we introduce a partition that allows us to compute, for the first t...

journal_title：Scientific reports

authors： Lima NB,Dutra JD,Gonçalves SM,Freire RO,Simas AM

更新日期：2016-02-19 00:00:00

abstract：:Monitoring ecological changes in marine ecosystems is expensive and time-consuming. Passive acoustic methods provide continuous monitoring of soniferous species, are relatively inexpensive, and can be integrated into a larger network to provide enhanced spatial and temporal coverage of ecological events. We demonstrat...

journal_title：Scientific reports

authors： Rycyk AM,Tyson Moore RB,Wells RS,McHugh KA,Berens McCabe EJ,Mann DA

更新日期：2020-10-20 00:00:00

abstract：:Sensing infrared radiation is done inexpensively with pyroelectric detectors that generate a temporary voltage when they are heated by the incident infrared radiation. Unfortunately the performance of these detectors deteriorates for longer wavelengths, leaving the detection of, for instance, millimetre-wave radiation...

journal_title：Scientific reports

authors： Kuznetsov SA,Paulish AG,Navarro-Cía M,Arzhannikov AV

更新日期：2016-02-16 00:00:00

abstract：:The aim of this study is to determine the prevalence and incidence of ankylosing spondylitis (AS) in South Korea, 2010-2015. This study was conducted using the Health Insurance Review Agency (HIRA) database, which includes information on every patient diagnosed with AS. The incidence and prevalence of AS were evaluate...

journal_title：Scientific reports

authors： Park JS,Hong JY,Park YS,Han K,Suh SW

更新日期：2018-05-16 00:00:00

abstract：:The natural alkaloid berberine has several pharmacological properties and recently received attention as a potential anticancer agent. In this work, we investigated the molecular mechanisms underlying the anti-tumor effect of berberine on glioblastoma U343 and pancreatic carcinoma MIA PaCa-2 cells. Human dermal fibrob...

journal_title：Scientific reports

authors： Agnarelli A,Natali M,Garcia-Gil M,Pesi R,Tozzi MG,Ippolito C,Bernardini N,Vignali R,Batistoni R,Bianucci AM,Marracci S

更新日期：2018-07-13 00:00:00

abstract：:Acid-sensing ion channels (ASICs) belong to the degenerin/epithelial sodium channel protein family that form mechanosensitive ion channels. Evidence as to whether or not ASICs activity is directly modulated by mechanical force is lacking. Human ASICs (hASIC1V3, hASIC2a and hASIC3a) were heterologously expressed as hom...

journal_title：Scientific reports

authors： Barth D,Fronius M

更新日期：2019-05-01 00:00:00

abstract：:Chemical chaperones including arginine and its derivatives are widely used by biochemists working on the design of agents, which are able to efficiently suppress protein aggregation. To elucidate the mechanisms of anti-aggregation activity of chemical chaperones, methods based on registration of the increment in light...

journal_title：Scientific reports

authors： Borzova VA,Markossian KA,Kleymenov SY,Kurganov BI

更新日期：2017-06-21 00:00:00

abstract：:We propose a novel scheme to realize an optical waveguide induced by an active Raman gain (ARG) process in a four-level N-type atomic system. Because of the nature of the ARG, there are two distinct features related to the waveguide: i) It is not absorptive, on the contrary, weak gain is presented; ii) It can be impro...

journal_title：Scientific reports

authors： Cui N,Gan Z,Zhang L

更新日期：2017-10-27 00:00:00

abstract：:Our study focused on radiocaesium (137Cs) partitioning in forests, three vegetation periods after the Fukushima Daiichi nuclear power plant accident. 137Cs distribution in forest components (organic and mineral soil layers as well as tree compartments: stem, bark, needles, branches and roots) was measured for two Japa...

journal_title：Scientific reports

authors： Coppin F,Hurtevent P,Loffredo N,Simonucci C,Julien A,Gonze MA,Nanba K,Onda Y,Thiry Y

更新日期：2016-11-23 00:00:00

abstract：:Tolerance to Dutch elm disease (DED) has been linked to the rapid and/or high induction of disease-responsive genes after infection with the fungus Ophiostoma novo-ulmi. Although the fungal infection by O. novo-ulmi primarily takes places in xylem vessels, it is still unclear how xylem contributes to the defense again...

journal_title：Scientific reports

authors： Sherif SM,Erland LA,Shukla MR,Saxena PK

更新日期：2017-08-02 00:00:00

abstract：:Previous research has shown that neighborhood-level variables such as social deprivation, social fragmentation or rurality are related to suicide risk, but most of these studies have been conducted in the U.S. or northern European countries. The aim of this study was to analyze the spatio-temporal distribution of suic...

journal_title：Scientific reports

authors： Marco M,Gracia E,López-Quílez A,Lila M

更新日期：2018-04-30 00:00:00

abstract：:To assess anatomical changes in eyes with progressive myopia, we morphometrically examined the eyes of guinea pigs with lens-induced axial elongation. Starting at an age of 3-4 weeks, guinea pigs in the experimental group (n = 20 animals) developed unilateral lens-induced axial elongation by wearing goggles for 5 week...

journal_title：Scientific reports

authors： Dong L,Shi XH,Kang YK,Wei WB,Wang YX,Xu XL,Gao F,Jonas JB

更新日期：2019-04-29 00:00:00

abstract：:Baeyer-Villiger monooxygenases (BVMOs) are able to catalyze regiospecific Baeyer-Villiger oxygenation of a variety of cyclic and linear ketones to generate the corresponding lactones and esters, respectively. However, the enzymes are usually difficult to express in a functional form in microbial cells and are rather u...

journal_title：Scientific reports

authors： Seo JH,Kim HH,Jeon EY,Song YH,Shin CS,Park JB

更新日期：2016-06-17 00:00:00

abstract：:The rectifying properties of α,ω-dithiol terminated oligo(phenylene ethynylene) molecules sandwiched between heterometallic electrodes, including the molecular length and side group effects, are theoretically investigated using the fully self-consistent nonequilibrium Green's function method combined with density func...

journal_title：Scientific reports

authors： Fu XX,Zhang RQ,Zhang GP,Li ZL

更新日期：2014-09-15 00:00:00

abstract：:Antidiabetic medication may modify the incidence of hepatocellular carcinoma (HCC). We aimed to compare the use of different antidiabetic strategies and the incidence of HCC. PubMed, Embase.com and Cochrane Library databases were searched up to 31 October 2015 and randomized controlled trials (RCTs), cohort studies or...

journal_title：Scientific reports

authors： Zhou YY,Zhu GQ,Liu T,Zheng JN,Cheng Z,Zou TT,Braddock M,Fu SW,Zheng MH

更新日期：2016-09-19 00:00:00

abstract：:The psychrophilic (cold-loving) fungus Pseudogymnoascus destructans was discovered more than a decade ago to be the pathogen responsible for white-nose syndrome, an emerging disease of North American bats causing unprecedented population declines. The same species of fungus is found in Europe but without associated mo...

journal_title：Scientific reports

authors： Ren P,Rajkumar SS,Zhang T,Sui H,Masters PS,Martinkova N,Kubátová A,Pikula J,Chaturvedi S,Chaturvedi V

更新日期：2020-08-17 00:00:00

abstract：:We propose a new express method of the correlation characterization of the particles suspended in the volume of optically transparent medium. It utilizes inline digital holography technique for obtaining two images of the adjacent layers from the investigated volume with subsequent matching of the cross-correlation fu...

journal_title：Scientific reports

authors： Vovk TA,Petrov NV

更新日期：2017-03-02 00:00:00

abstract：:Ferromagnetism can occur in wide-band gap semiconductors as well as in carbon-based materials when specific defects are introduced. It is thus desirable to establish a direct relation between the defects and the resulting ferromagnetism. Here, we contribute to revealing the origin of defect-induced ferromagnetism usin...

journal_title：Scientific reports

authors： Wang Y,Liu Y,Wang G,Anwand W,Jenkins CA,Arenholz E,Munnik F,Gordan OD,Salvan G,Zahn DR,Chen X,Gemming S,Helm M,Zhou S

更新日期：2015-03-11 00:00:00

abstract：:Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or gastrointestinal obstruction....

journal_title：Scientific reports

authors： Chang CS,Wallace CG,Hsiao YC,Huang JJ,Chen ZC,Chang CJ,Lo LJ,Chen PK,Chen JP,Chen YR

更新日期：2018-05-09 00:00:00

abstract：:Plasmacytoid dendritic cells (pDCs) are specialized in the production of interferons (IFNs) in response to viral infections. The Flaviviridae family comprises enveloped RNA viruses such as Hepatitis C virus (HCV) and Dengue virus (DENV). Cell-free flaviviridae virions poorly stimulate pDCs to produce IFN. By contrast,...

journal_title：Scientific reports

authors： Sinigaglia L,Gracias S,Décembre E,Fritz M,Bruni D,Smith N,Herbeuval JP,Martin A,Dreux M,Tangy F,Jouvenet N

更新日期：2018-07-18 00:00:00