Potential for sub-mm long erbium-doped composite silicon waveguide DFB lasers.

abstract：:To better understand the brain function based on neural activity, a minimally invasive analysis technology in a freely moving animal is necessary. Such technology would provide new knowledge in neuroscience and contribute to regenerative medical techniques and prosthetics care. An application that combines optogenetic...

journal_title：Scientific reports

authors： Kobayashi T,Haruta M,Sasagawa K,Matsumata M,Eizumi K,Kitsumoto C,Motoyama M,Maezawa Y,Ohta Y,Noda T,Tokuda T,Ishikawa Y,Ohta J

更新日期：2016-02-16 00:00:00

abstract：:Plastic pollution is a rapidly worsening environmental problem, especially in oceanic habitats. Environmental pollution with microplastic particles is also causing food consumed by humans to be increasingly polluted, including table salts. Therefore, we present the first study which focuses only on table salt products...

journal_title：Scientific reports

authors： Lee H,Kunz A,Shim WJ,Walther BA

更新日期：2019-07-12 00:00:00

abstract：:In this paper, the effect of binder decay rather than a change in the pigments on the blurring of ancient wall paintings was researched. The simulated wall paintings were prepared by brushing an aqueous solution containing gelatine and ochre grains on the surface of cylindrical compressed soil samples. Then, the dried...

journal_title：Scientific reports

authors： Zheng L,Wang Z,Shen S,Xia Y,Li Y,Hu D

更新日期：2020-12-03 00:00:00

abstract：:Dengue virus (DENV) causes a wide range of illnesses in humans, including dengue fever and dengue haemorrhagic fever. Current animal models of DENV infection are limited for understanding infectious diseases in humans. Bonnet monkeys (Macaca radiata), a type of Old World monkey, have been used to study experimental an...

journal_title：Scientific reports

authors： Kato F,Ishida Y,Kawakami A,Takasaki T,Saijo M,Miura T,Hishiki T

更新日期：2018-02-21 00:00:00

abstract：:The quantification of hepatitis C virus (HCV) is essential for the management of chronic hepatitis C therapy. We have developed a fully automated microfluidic RT-qPCR system for rapid quantitative detection of HCV RNA in human EDTA-plasma and serum, and the performance of the method was assessed. The platform for the ...

journal_title：Scientific reports

authors： Chan SDH,Toyoda H,Sanjeeviraman J,Souppe A,Iwamoto M,Wu W,Eto D,Tada T,Kumada T,Zhang JP

更新日期：2020-04-30 00:00:00

abstract：:Fusarium wilt is one of the major biotic stresses reducing chickpea productivity. The use of wilt-resistant cultivars is the most appropriate means to combat the disease and secure productivity. As a step towards understanding the molecular basis of wilt resistance in chickpea, we investigated the transcriptomes of wi...

journal_title：Scientific reports

authors： Upasani ML,Limaye BM,Gurjar GS,Kasibhatla SM,Joshi RR,Kadoo NY,Gupta VS

更新日期：2017-08-10 00:00:00

abstract：:Heat shock factor-1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins by stimulating the transcription of genes encoding heat shock proteins (HSPs). This stimulatory action depends on the association of trimeric HSF1 to sequences within HSP gene promoters. However, we recently describ...

journal_title：Scientific reports

authors： Qu Z,Titus ASCLS,Xuan Z,D'Mello SR

更新日期：2018-11-22 00:00:00

abstract：:Hydrogels are being extensively used for three-dimensional immobilization and culture of cells in fundamental biological studies, biochemical processes, and clinical treatments. However, it is still a challenge to support viability and regulate phenotypic activities of cells in a structurally stable gel, because the g...

journal_title：Scientific reports

authors： Lee MK,Rich MH,Baek K,Lee J,Kong H

更新日期：2015-03-10 00:00:00

abstract：:Microalgae have great potential for the production of biofuels due to the ability of the organism to accumulate large quantities of storage lipids under stress conditions. Mitogen activated protein kinase (MAPK) signaling cascades are widely recognized for their role in stress response signal transduction in eukaryote...

journal_title：Scientific reports

authors： Yang A,Suh WI,Kang NK,Lee B,Chang YK

更新日期：2018-09-14 00:00:00

abstract：:Hepatitis C virus (HCV) uses components of the very-low-density lipoprotein (VLDL) pathway for assembly/release. We previously reported that hepatocyte nuclear factor 4α (HNF4α) participates in HCV assembly/release through downstream factors those participate in VLDL assembly/secretion. Cell-death-inducing DFFA-like e...

journal_title：Scientific reports

authors： Cai H,Yao W,Li L,Li X,Hu L,Mai R,Peng T

更新日期：2016-06-10 00:00:00

abstract：:The primary hurdle for diagnosis of some diseases is the long incubation required to culture and confirm the presence of bacteria. The concept of using microbial VOCs as "signature markers" could provide a faster and noninvasive diagnosis. Finding biomarkers is challenging due to the specificity required in complex ma...

journal_title：Scientific reports

authors： Maurer DL,Ellis CK,Thacker TC,Rice S,Koziel JA,Nol P,VerCauteren KC

更新日期：2019-08-20 00:00:00

abstract：:Liquid biopsy can provide a strong basis for precision medicine. We aimed to identify novel single-nucleotide variants (SNVs) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Deep sequencing of plasma-derived ctDNA from 59 patients with HCC was performed using a panel of 2924 SNVs in 6...

journal_title：Scientific reports

authors： Kim SS,Eun JW,Choi JH,Woo HG,Cho HJ,Ahn HR,Suh CW,Baek GO,Cho SW,Cheong JY

更新日期：2020-10-20 00:00:00

abstract：:Freeze-thaw cycles are predicted to increase in cold temperate regions. The potential influence of the interactions of freeze-thaw cycles and agrochemicals on the release of Cd into river water is unknown. In this study, the interactions of freeze-thaw cycles and chlorpyrifos (FC) on Cd mobility in soils were analysed...

journal_title：Scientific reports

authors： Wang F,Ouyang W,Hao F,Jiao W,Shan Y,Lin C

更新日期：2016-06-02 00:00:00

abstract：:Plant genomes encode several classes of small regulatory RNAs (sRNAs) that play critical roles in both development and stress responses. Panax notoginseng (Burk.) F.H. Chen (P. notoginseng) is an important traditional Chinese herbal medicinal plant species for its haemostatic effects. Therefore, the root yield of P. n...

journal_title：Scientific reports

authors： Zheng Y,Chen K,Xu Z,Liao P,Zhang X,Liu L,Wei K,Liu D,Li YF,Sunkar R,Cui X

更新日期：2017-08-25 00:00:00

abstract：:Three-dimensional (3D) spheroidal cell cultures are now recognised as better models of cancers as compared to traditional cell cultures. However, established 3D cell culturing protocols and techniques are time-consuming, manually laborious and often expensive due to the excessive consumption of reagents. Microfluidics...

journal_title：Scientific reports

authors： Khot MI,Levenstein MA,de Boer GN,Armstrong G,Maisey T,Svavarsdottir HS,Andrew H,Perry SL,Kapur N,Jayne DG

更新日期：2020-09-28 00:00:00

abstract：:Cardiac progenitor cells (CPCs) have been shown to promote cardiac regeneration and improve heart function. However, evidence suggests that their regenerative capacity may be limited in conditions of severe hypoxia. Elucidating the mechanisms involved in CPC protection against hypoxic stress is essential to maximize t...

journal_title：Scientific reports

authors： Bellio MA,Pinto MT,Florea V,Barrios PA,Taylor CN,Brown AB,Lamondin C,Hare JM,Schulman IH,Rodrigues CO

更新日期：2017-08-29 00:00:00

abstract：:Herein, by growing mono dispersed gold nanoparticles (MNPAu) on the surface of polystyrene (PS)/nanogold (Au) core-shell composites (PS@Au), we successfully synthesized a micron-sized gold cage (2.6-10.7 μm), referred to as PS@Au@MNPAu for the first time. The new micron-gold cage materials exhibit broadband absorption...

journal_title：Scientific reports

authors： Dong S,Yi L,Cheng L,Li S,Yang W,Wang Z,Jiang S

更新日期：2020-10-06 00:00:00

abstract：:Brønsted-Lewis acidic ionic liquids (ILs) were applied to catalyze cellobiose to prepare levulinic acid (LA) in one pot under hydrothermal conditions. Under the optimum conditions, the highest LA yield of 67.51% was obtained when low [HO3S-(CH2)3-mim]Cl-FeCl3 (molar fraction of FeCl3 x = 0.60) was used. This indicated...

journal_title：Scientific reports

authors： Liu S,Wang K,Yu H,Li B,Yu S

更新日期：2019-02-12 00:00:00

abstract：:In this paper, we developed a new method to produce large-area single crystal arrays by using the organic semiconductor 9, 10-bis (phenylethynyl) anthracene (BPEA). This method involves an easy operation, is efficient, meets the demands of being low-cost and is independent of the substrate for large-area arrays fabric...

journal_title：Scientific reports

authors： Li Y,Ji D,Liu J,Yao Y,Fu X,Zhu W,Xu C,Dong H,Li J,Hu W

更新日期：2015-08-18 00:00:00

abstract：:The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show th...

journal_title：Scientific reports

authors： Vo U,Vajpai N,Embrey KJ,Golovanov AP

更新日期：2016-07-14 00:00:00

abstract：:An increasing number of industrial applications need superstrength steels. It is known that refined grains and nanoscale precipitates can increase strength. The hardest martensitic steel reported to date is C0.8 steel, whose nanohardness can reach 11.9 GPa through incremental interstitial solid solution strengthening....

journal_title：Scientific reports

authors： Yu H,Yan M,Lu C,Tieu AK,Li H,Zhu Q,Godbole A,Li J,Su L,Kong C

更新日期：2016-11-28 00:00:00

abstract：:The physiological, biochemical and functional differences between oxidative and glycolytic muscles play important roles in human metabolic health and in animal meat quality. To explore these differences, we determined the genome-wide landscape of DNA methylomes and their relationship with the mRNA and miRNA transcript...

journal_title：Scientific reports

authors： Shen L,Du J,Xia Y,Tan Z,Fu Y,Yang Q,Li X,Tang G,Jiang Y,Wang J,Li M,Zhang S,Zhu L

更新日期：2016-08-26 00:00:00

abstract：:Live birth is the most important concern for assisted reproductive technology (ART) patients. Therefore, in the medical reproductive centre, obstetricians often need to answer the following question: "What are the chances that I will have a healthy baby after ART treatment?" To date, our obstetricians have no referenc...

journal_title：Scientific reports

authors： Gao H,Liu DE,Li Y,Wu X,Tan H

更新日期：2021-01-11 00:00:00

abstract：:To resolve the pore-associated bottleneck problem observed in the electrode materials used for ultracapacitors, which inhibits the transport of the electrolyte ions, we designed hierarchically structured activated carbon (HAC) by synthesizing a mesoporous silica template/carbon composite and chemically activating it t...

journal_title：Scientific reports

authors： Kim MH,Kim KB,Park SM,Roh KC

更新日期：2016-02-16 00:00:00

abstract：:Alternative polyadenylation has been recognized as a key contributor of gene expression regulation by generating different transcript isoforms with altered 3' ends. Although polyadenylation is well known for marking the end of a 3' UTR, an increasing number of studies have reported previously less-addressed polyadenyl...

journal_title：Scientific reports

authors： Guo C,Spinelli M,Liu M,Li QQ,Liang C

更新日期：2016-06-15 00:00:00

abstract：:Multi-modal three dimensional (3D) optical imaging combining both structural sensitivity and molecular specificity is highly desirable in biomedical research. In this paper, we present a method termed oblique scanning laser microscopy (OSLM) to combine optical coherence tomography (OCT), for simultaneously volumetric ...

journal_title：Scientific reports

authors： Zhang L,Capilla A,Song W,Mostoslavsky G,Yi J

更新日期：2017-08-17 00:00:00

abstract：:Integrins coupled with other proteins form protein complexes named focal adhesions (FA) which are considered as the primary sites for cellular forces transduction during cell stable adhesion. Cell traction forces transmitted by FAs and integrin tensions inside FAs have been extensively studied. However, it remains unk...

journal_title：Scientific reports

authors： Wang Y,Wang X

更新日期：2016-11-15 00:00:00

abstract：:Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...

journal_title：Scientific reports

authors： Koide M,Yamashita T,Murakami K,Uehara S,Nakamura K,Nakamura M,Matsushita M,Ara T,Yasuda H,Penninger JM,Takahashi N,Udagawa N,Kobayashi Y

更新日期：2020-08-13 00:00:00

abstract：:Sequence-controlled polymers (SCPs) such as DNA and proteins play an important role in biology. Many efforts have been devoted to synthesize SCPs in the past half a century. However, to our knowledge, the artificial sequences containing independently functional groups have never been reported. Here, we present a facil...

journal_title：Scientific reports

authors： Han J,Zheng Y,Zhao B,Li S,Zhang Y,Gao C

更新日期：2014-03-17 00:00:00

abstract：:Radionuclide molecular imaging of HER2 expression in disseminated cancer enables stratification of patients for HER2-targeted therapies. DARPin G3, a small (14 kDa) engineered scaffold protein, is a promising probe for imaging of HER2. We hypothesized that position (C- or N-terminus) and composition (hexahistidine or ...

journal_title：Scientific reports

authors： Vorobyeva A,Schulga A,Konovalova E,Güler R,Löfblom J,Sandström M,Garousi J,Chernov V,Bragina O,Orlova A,Tolmachev V,Deyev SM

更新日期：2019-06-28 00:00:00