Blurring of ancient wall paintings caused by binder decay in the pigment layer.

abstract：:Sex-based variations in the immune response to the influenza vaccines was reported, however, the genetic basis responsible for the sex variations in the immune response toward the influenza vaccines remains unclear. Here, the genes responsible for sex-specific responses after vaccination with trivalent inactivated inf...

journal_title：Scientific reports

authors： Wen F,Guo J,Li Z,Huang S

更新日期：2018-09-10 00:00:00

abstract：:Primary cultured cardiomyocytes show spontaneous Ca2+ oscillations (SCOs) which not only govern contractile events, but undergo derangements that promote arrhythmogenesis through Ca2+ -dependent mechanism. We systematically examined influence on SCOs of an array of ion channel modifiers by recording intracellular Ca2+...

journal_title：Scientific reports

authors： Li X,Shen L,Zhao F,Zou X,He Y,Zhang F,Zhang C,Yu B,Cao Z

更新日期：2017-01-19 00:00:00

abstract：:We propose two generalized Haldane models on laser-coupling optical lattices. Laser-assisted nearest neighbour tunnelings generate artificial staggered magnetic flux, facilitating the realization of topological nontrivial band structures. As generalizations of Haldane model, these models support topological insulator ...

journal_title：Scientific reports

authors： Liu W,Lin Z,Wang ZD,Chen Y

更新日期：2018-08-27 00:00:00

abstract：:The resistance-nodulation-cell division (RND)-type xenobiotic efflux system plays a major role in the multidrug resistance of gram-negative bacteria. The only constitutively expressed RND system of Escherichia coli consists of the inner membrane transporter AcrB, the membrane fusion protein AcrA, and the outer membran...

journal_title：Scientific reports

authors： Yamamoto K,Tamai R,Yamazaki M,Inaba T,Sowa Y,Kawagishi I

更新日期：2016-02-26 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： El-Zahar ER,Rashad AM,Saad W,Seddek LF

更新日期：2020-09-24 00:00:00

abstract：:Sigma-1 and sigma-2 receptors are emerging therapeutic targets. We have identified that simple ammonium salts bind to these receptors and are effective in vivo. Radioligand binding assays were used to obtain structure-activity relationships of these salts. MTS assays were performed to determine their effect on growth ...

journal_title：Scientific reports

authors： Brimson JM,Akula KK,Abbas H,Ferry DR,Kulkarni SK,Russell ST,Tisdale MJ,Tencomnao T,Safrany ST

更新日期：2020-06-08 00:00:00

abstract：:Characterizing the genetic diversity of microbial copper (Cu) resistance at the community level remains challenging, mainly due to the polymorphism of the core functional gene copA. In this study, a local BLASTN method using a copA database built in this study was developed to recover full-length putative copA sequenc...

journal_title：Scientific reports

authors： Li X,Zhu YG,Shaban B,Bruxner TJ,Bond PL,Huang L

更新日期：2015-08-19 00:00:00

abstract：:Subsolid pulmonary nodules are commonly encountered in lung cancer screening and clinical routine. Compared to other nodule types, subsolid nodules are associated with a higher malignancy probability for which the size and mass of the nodule and solid core are important indicators. However, reliably measuring these ch...

journal_title：Scientific reports

authors： Charbonnier JP,Chung K,Scholten ET,van Rikxoort EM,Jacobs C,Sverzellati N,Silva M,Pastorino U,van Ginneken B,Ciompi F

更新日期：2018-01-12 00:00:00

abstract：:Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas. From ...

journal_title：Scientific reports

authors： Zheng HX,Yan S,Qin ZD,Jin L

更新日期：2012-01-01 00:00:00

abstract：:We propose an ultrathin metallic structure to produce frequency-selective spoof surface plasmon polaritons (SPPs) in the microwave and terahertz frequencies. Designed on a thin dielectric substrate, the ultrathin metallic structure is composed of two oppositely oriented single-side corrugated strips, which are coupled...

journal_title：Scientific reports

authors： Yin JY,Ren J,Zhang HC,Pan BC,Cui TJ

更新日期：2015-02-02 00:00:00

abstract：:The discovery of the insertion of IbT-DNA1 and IbT-DNA2 into the cultivated (hexaploid) sweetpotato [Ipomoea batatas (L.) Lam.] genome constitutes a clear example of an ancient event of Horizontal Gene Transfer (HGT). However, it remains unknown whether the acquisition of both IbT-DNAs by the cultivated sweetpotato oc...

journal_title：Scientific reports

authors： Quispe-Huamanquispe DG,Gheysen G,Yang J,Jarret R,Rossel G,Kreuze JF

更新日期：2019-08-29 00:00:00

abstract：:The transition energies and formation energies of N, C, F, Cl, and S as substitutional dopants in Ag3PO4 are studied using first-principles calculations based on the hybrid Hartree-Fock density functional, which correctly reproduces the band gap and thus provides the accurate defect states. Our results show that NO an...

journal_title：Scientific reports

authors： Huang Y,Ma T,Chen QY,Cao C,He Y

更新日期：2015-08-03 00:00:00

abstract：:A typical assumption made in the existing opinion formation models is that two individuals can communicate with each other only if the distance between their opinions is less than a threshold called bound of confidence. However, in the real world it is quite possible that people may also have a few friends with quite ...

journal_title：Scientific reports

authors： Liu Q,Wang X

更新日期：2013-10-17 00:00:00

abstract：:Promoter activation drives gene transcriptional output. Here we report generating site-specifically integrated single-copy promoter transgenes and measuring their expression to indicate promoter activities at single-mRNA level. mRNA counts, Pol II density and Pol II firing rates of the Ccnb1 promoter transgene resembl...

journal_title：Scientific reports

authors： Vishnoi N,Yao J

更新日期：2017-05-18 00:00:00

abstract：:The raccoon dog (Nyctereutes procyonoides) is an important canid fur-bearing animal species worldwide. Chinese raccoon dogs that present a white mutation, especially those with a white coat. Exploring melanin biosynthesis in the hair and skin of raccoon dogs is important for understanding the survival and evolutionary...

journal_title：Scientific reports

authors： Du Z,Huang K,Zhao J,Song X,Xing X,Wu Q,Zhang L,Xu C

更新日期：2017-01-18 00:00:00

abstract：:Nanoparticles are widely used in commodities, and pregnant women are inevitably exposed to these particles. The placenta protects the growing fetus from foreign or toxic materials, and provides energy and oxygen. Here we report that autophagy, a cellular mechanism to maintain homeostasis, engulfs platinum nanoparticle...

journal_title：Scientific reports

authors： Nakashima A,Higashisaka K,Kusabiraki T,Aoki A,Ushijima A,Ono Y,Tsuda S,Shima T,Yoshino O,Nagano K,Yoshioka Y,Tsutsumi Y,Saito S

更新日期：2019-04-02 00:00:00

abstract：:Prescribing the right drug with the right dose is a central tenet of precision medicine. We examined the use of patients' prior Electronic Health Records to predict a reduction in drug dosage. We focus on drugs that interact with the P450 enzyme family, because their dosage is known to be sensitive and variable. We ex...

journal_title：Scientific reports

authors： Coulet A,Shah NH,Wack M,Chawki MB,Jay N,Dumontier M

更新日期：2018-10-22 00:00:00

abstract：:The over-expression and aggregation of α-synuclein (αSyn) are linked to the onset and pathology of Parkinson's disease. Native monomeric αSyn exists in an intrinsically disordered ensemble of interconverting conformations, which has made its therapeutic targeting by small molecules highly challenging. Nonetheless, her...

journal_title：Scientific reports

authors： Tóth G,Neumann T,Berthet A,Masliah E,Spencer B,Tao J,Jobling MF,Gardai SJ,Bertoncini CW,Cremades N,Bova M,Ballaron S,Chen XH,Mao W,Nguyen P,Tabios MC,Tambe MA,Rochet JC,Junker HD,Schwizer D,Sekul R,Ott I,Ander

更新日期：2019-11-18 00:00:00

abstract：:There are at least two different principles of how ADP-ribose (ADPR) induces activation of TRPM2 channels. In human TRPM2, gating requires the C-terminal NUDT9H domain as ADPR-binding module, whereas in sea anemone, NUDT9H is dispensable and binding of ADPR occurs N-terminally. Zebrafish TRPM2 needs both, the N-termin...

journal_title：Scientific reports

authors： Kühn FJP,Ehrlich W,Barth D,Kühn C,Lückhoff A

更新日期：2019-12-16 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract of uncertain origin, which includes ulcerative colitis (UC) and Crohn's disease (CD). The composition of gut microbiota may change in IBD affected individuals, but whether dysbiosis is the cause or the consequence of infla...

journal_title：Scientific reports

authors： Santoru ML,Piras C,Murgia A,Palmas V,Camboni T,Liggi S,Ibba I,Lai MA,Orrù S,Blois S,Loizedda AL,Griffin JL,Usai P,Caboni P,Atzori L,Manzin A

更新日期：2017-08-25 00:00:00

abstract：:Total Grain-Size Distribution (TGSD) of tephra deposits is key to the characterization of explosive volcanism, plume-dispersal modeling, and magmatic fragmentation studies. Nonetheless, various aspects that includes deposit exposure and data fitting make its determination extremely complex and affect its representativ...

journal_title：Scientific reports

authors： Pioli L,Bonadonna C,Pistolesi M

更新日期：2019-07-10 00:00:00

abstract：:Global ocean acidification is expected to chronically lower the pH to 7.3 (>2200 µatm seawater pCO2) by the year 2300. Acute hypercapnia already occurs along the South African west and south coasts due to upwelling- and low-oxygen events, with increasing frequency. In the present project we investigated the impact of ...

journal_title：Scientific reports

authors： Dziergwa J,Singh S,Bridges CR,Kerwath SE,Enax J,Auerswald L

更新日期：2019-12-19 00:00:00

abstract：:Birds have a highly specialized and efficient digestive system, but when this system originated remains uncertain. Here we report six gastric pellets attributable to the recently discovered 160-million-year-old troodontid dinosaur Anchiornis, which is among the key taxa for understanding the transition to birds. The g...

journal_title：Scientific reports

authors： Zheng X,Wang X,Sullivan C,Zhang X,Zhang F,Wang Y,Li F,Xu X

更新日期：2018-09-21 00:00:00

abstract：:Method for production of alpha emitter 149Tb by irradiation of 151Eu with 70 MeV 3He nuclei is proposed. For the first time, the cross sections for the formation of isotopes 149,150,151,152Tb were measured experimentally using a stack foil technique in the 3He particles energy range 70 → 12 MeV. The thick target yield...

journal_title：Scientific reports

authors： Moiseeva AN,Aliev RA,Unezhev VN,Zagryadskiy VA,Latushkin ST,Aksenov NV,Gustova NS,Voronuk MG,Starodub GY,Ogloblin AA

更新日期：2020-01-16 00:00:00

abstract：:In this study, a novel resorufin thionocarbonate-based Hg2+-selective signaling probe (RT) for microfluidic paper-based analytical device (μPAD) applications is reported. The designed probe, RT, was readily synthesized by the one-step reaction of resorufin with phenyl thionochloroformate. The RT probe displayed a prom...

journal_title：Scientific reports

authors： Choi MG,Park SY,Park KY,Chang SK

更新日期：2019-03-04 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive immune-mediated joint deterioration. Current treatments are not antigen specific and are associated with various adverse. We have previously demonstrated that tolerogenic dendritic cells (Tol-DC) are potent antigen-specific immune regulato...

journal_title：Scientific reports

authors： Li R,Zhang Y,Zheng X,Peng S,Yuan K,Zhang X,Min W

更新日期：2017-02-23 00:00:00

abstract：:Marine crabs inhabit shallow coastal/estuarine habitats particularly sensitive to climate change, and yet we know very little about the diversity of their responses to environmental change. We report the effects of a rarely studied, but increasingly prevalent, combination of environmental factors, that of near-future ...

journal_title：Scientific reports

authors： Whiteley NM,Suckling CC,Ciotti BJ,Brown J,McCarthy ID,Gimenez L,Hauton C

更新日期：2018-10-23 00:00:00

abstract：:The barnase-barstar complex is one of the most stable protein-protein complexes and has a very wide range of possible applications. Here we report the use of top-down mass spectrometry for the investigation of the structure of this complex, its ionization via ESI, isolation and fragmentation. It was found that the asy...

journal_title：Scientific reports

authors： Kostyukevich Y,Shulga AA,Kononikhin A,Popov I,Nikolaev E,Deyev S

更新日期：2017-07-21 00:00:00

abstract：:We conducted a prospective cohort study among HIV-negative MSM aged 18 years or older between 2007 and 2012 in Beijing, China to measure the rates of incident HIV and identify risk factors for infection. Among 5,800 participants evaluated at enrollment, we identified 486 prevalent cases of HIV (8.4%). Among the 3,625 ...

journal_title：Scientific reports

authors： Jia Z,Huang X,Wu H,Zhang T,Li N,Ding P,Sun Y,Liu Z,Wei F,Zhang H,Jiao Y,Ji Y,Zhang Y,Guo C,Li W,Mou D,Xia W,Li Z,Chen D,Yan H,Chen X,Zhao J,Meyers K,Cohen T,Mayer K,Salomon JA,Lu Z,Dye C

更新日期：2015-07-02 00:00:00

abstract：:High-resolution spectroscopy in the 1-10 μm region has never been fully tackled for the lack of widely-tunable and practical light sources. Indeed, all solutions proposed thus far suffer from at least one of three issues: they are feasible only in a narrow spectral range; the power available for spectroscopy is limite...

journal_title：Scientific reports

authors： Insero G,Borri S,Calonico D,Pastor PC,Clivati C,D'Ambrosio D,De Natale P,Inguscio M,Levi F,Santambrogio G

更新日期：2017-10-06 00:00:00