Screening of Microbial Volatile Organic Compounds for Detection of Disease in Cattle: Development of Lab-scale Method.

abstract：:EhV-ATPase is an ATP-driven Na+ pump in the eubacteria Enterococcus hirae (Eh). Here, we present the first entire structure of detergent-solubilized EhV-ATPase by single-particle cryo-electron microscopy (cryo-EM) using Zernike phase plate. The cryo-EM map dominantly showed one of three catalytic conformations in this...

journal_title：Scientific reports

authors： Tsunoda J,Song C,Imai FL,Takagi J,Ueno H,Murata T,Iino R,Murata K

更新日期：2018-10-23 00:00:00

abstract：:The topotactic phase transition in SrCoO x (x = 2.5-3.0) makes it possible to reversibly transit between the two distinct phases, i.e. the brownmillerite SrCoO2.5 that is a room-temperature antiferromagnetic insulator (AFM-I) and the perovskite SrCoO3 that is a ferromagnetic metal (FM-M), owing to their multiple valen...

journal_title：Scientific reports

authors： Lee JH,Choi WS,Jeen H,Lee HJ,Seo JH,Nam J,Yeom MS,Lee HN

更新日期：2017-11-22 00:00:00

abstract：:We propose a new method to extend the path length tunability of rotary delay-lines. This method was shown to achieve a duty cycle of >80% and repetition rates of over 40 kHz. The new method relies on a new multi-segmented micro-machined mirror and serial injection of a single reflection onto separate segments of this ...

journal_title：Scientific reports

authors： Fleddermann R,Lee WM,Huang K,Campbell GT,Lam PK,Chow JH

更新日期：2017-08-24 00:00:00

abstract：:Vitamin D deficiency, a major public-health worldwide, is associated with hyperuricemia but casual association is questioned. The study was conducted to determine potential causal associations between 25-hydroxy vitamin D (25(OH)D) and uric acid (UA). A cross-sectional study of the Electricity Generating Authority of ...

journal_title：Scientific reports

authors： Thakkinstian A,Anothaisintawee T,Chailurkit L,Ratanachaiwong W,Yamwong S,Sritara P,Ongphiphadhanakul B

更新日期：2015-09-29 00:00:00

abstract：:Features from Electrovestibulography (EVestG) recordings have been used to classify and measure the severity of both persistent post-concussion syndrome (PCS) and major depressive disorder. Herein, we examined the effect of comorbid depression on the detection of persistent PCS using EVestG. To validate our previously...

journal_title：Scientific reports

authors： Suleiman A,Lithgow B,Mansouri B,Moussavi Z

更新日期：2018-09-27 00:00:00

abstract：:The estrogen signaling pathway has been reported to modulate prostate cancer (PCa) progression through the activity of estrogen receptors α and β (ERα and ERβ). Given that selective estrogen receptor modulators (SERMs) are used to treat breast cancer, ERs have been proposed as attractive therapeutic targets in PCa. Ho...

journal_title：Scientific reports

authors： Lafront C,Germain L,Weidmann C,Audet-Walsh É

更新日期：2020-03-04 00:00:00

abstract：:Species of kalanchoe are rich in bioactive compounds and are widely used in folk medicine; however, these plants are not well known from the point of view of aroma. Two species, Kalanchoe pinnata and Kalanchoe daigremontiana, were examined after six months and two years of growth and their vitamin C content, succulenc...

journal_title：Scientific reports

authors： Zawirska-Wojtasiak R,Jankowska B,Piechowska P,Mildner-Szkudlarz S

更新日期：2019-12-24 00:00:00

abstract：:Hybrid cells of Nicotiana suaveolens x N. tabacum grow normally at 36 °C, but immediately express lethality due to probable autoimmune response when transferred from 36 to 28 °C. Our recent study showed that the temperature-sensitive lethality of these hybrid cells occurs through autolytic programmed cell death (PCD)....

journal_title：Scientific reports

authors： Ueno N,Kashiwagi M,Kanekatsu M,Marubashi W,Yamada T

更新日期：2019-07-15 00:00:00

abstract：:Medium chain fatty acids can activate the pro-inflammatory receptor GPR84 but so also can molecules related to 3,3'-diindolylmethane. 3,3'-Diindolylmethane and decanoic acid acted as strong positive allosteric modulators of the function of each other and analysis showed the affinity of 3,3'-diindolylmethane to be at l...

journal_title：Scientific reports

authors： Mahmud ZA,Jenkins L,Ulven T,Labéguère F,Gosmini R,De Vos S,Hudson BD,Tikhonova IG,Milligan G

更新日期：2017-12-20 00:00:00

abstract：:Available CFTR modulators provide no therapeutic benefit for cystic fibrosis (CF) caused by many loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, including N1303K. We previously introduced the concept of 'co-potentiators' (combination-potentiators) to rescu...

journal_title：Scientific reports

authors： Phuan PW,Tan JA,Rivera AA,Zlock L,Nielson DW,Finkbeiner WE,Haggie PM,Verkman AS

更新日期：2019-11-27 00:00:00

abstract：:Metal-insulator transition is observed in the La0.8Sr0.2MnO3 thin films with thickness larger than 5 unit cells. Insulating phase at lower temperature appeared in the ultrathin films with thickness ranging from 6 unit cells to 10 unit cells and it is found that the Mott variable range hopping conduction dominates in t...

journal_title：Scientific reports

authors： Feng Y,Jin KJ,Gu L,He X,Ge C,Zhang QH,He M,Guo QL,Wan Q,He M,Lu HB,Yang G

更新日期：2016-03-01 00:00:00

abstract：:A novel design of thin-film crystalline silicon solar cell (TF C-Si-SC) is proposed and numerically analyzed. The reported SC has 1.0 µm thickness of C-Si with embedded dielectric silicon dioxide nanowires (NWs). The introduced NWs increase the light scattering in the active layer which improves the optical path lengt...

journal_title：Scientific reports

authors： Elrabiaey MA,Hussein M,Hameed MFO,Obayya SSA

更新日期：2020-10-16 00:00:00

abstract：:Imputation is a computational method based on the principle of haplotype sharing allowing enrichment of genome-wide association study datasets. It depends on the haplotype structure of the population and density of the genotype data. The 1000 Genomes Project led to the generation of imputation reference panels which h...

journal_title：Scientific reports

authors： Ahmad M,Sinha A,Ghosh S,Kumar V,Davila S,Yajnik CS,Chandak GR

更新日期：2017-07-27 00:00:00

abstract：:Most organisms are able to maintain systemic water homeostasis over a wide range of external or dietary osmolarities. The excretory system, composed of the kidneys in mammals and the Malpighian tubules and hindgut in insects, can increase water conservation and absorption to maintain systemic water homeostasis, which ...

journal_title：Scientific reports

authors： Luan Z,Quigley C,Li HS

更新日期：2015-01-23 00:00:00

abstract：:Fatty acid oxidation is the major energy pathway used by the kidney, although glycolysis becomes more important in the low oxygen environment of the medulla. Fatty acid oxidation appears to be reduced in renal fibrosis, and drugs that reverse this improve fibrosis. Expression of glycolytic genes is more variable, but ...

journal_title：Scientific reports

authors： Lee M,Harley G,Katerelos M,Gleich K,Sullivan MA,Laskowski A,Coughlan M,Fraser SA,Mount PF,Power DA

更新日期：2020-09-03 00:00:00

abstract：:In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined phenotypic and transcriptome-wide studies and showed that the stimulation of the LUSC cell line SK-MES1 with TGF...

journal_title：Scientific reports

authors： Dvornikov D,Schneider MA,Ohse S,Szczygieł M,Titkova I,Rosenblatt M,Muley T,Warth A,Herth FJ,Dienemann H,Thomas M,Timmer J,Schilling M,Busch H,Boerries M,Meister M,Klingmüller U

更新日期：2018-06-22 00:00:00

abstract：:Combined treatment with 5-aminolevulinic acid (5-ALA) and X-rays improves tumor suppression in vivo. This is because the accumulated protoporphyrin IX from 5-ALA enhances the generation of ROS by the X-ray irradiation. In the present study, a high-energy medical linear accelerator was used instead of a non-medical low...

journal_title：Scientific reports

authors： Takahashi J,Murakami M,Mori T,Iwahashi H

更新日期：2018-02-09 00:00:00

abstract：:Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum Tower Hospital, Jiangsu province of eastern China. Relative telomere length (RTL) of...

journal_title：Scientific reports

authors： Weng Q,Deng K,Wu F,Gan M,Li J,Dai Y,Jiang Y,Chen J,Dai J,Ma H,Hu Z,Shen H,Du J,Hu Y,Jin G

更新日期：2019-06-11 00:00:00

abstract：:Solving river engineering problems typically requires river flow characterization, including the prediction of flow depth, flow velocity, and flood extent. Hydraulic models use governing equations of the flow in motion (conservation of mass and momentum principles) to predict the flow characteristics. However, solving...

journal_title：Scientific reports

authors： Hosseiny H,Nazari F,Smith V,Nataraj C

更新日期：2020-05-19 00:00:00

abstract：:Plasmodium vivax, a major agent of malaria in both temperate and tropical climates, has been thought to be unable to infect humans lacking the Duffy (Fy) blood group antigen because this receptor is critical for erythrocyte invasion. Recent surveys in various endemic regions, however, have reported P. vivax infections...

journal_title：Scientific reports

authors： Cheng Y,Lu F,Wang B,Li J,Han JH,Ito D,Kong DH,Jiang L,Wu J,Ha KS,Takashima E,Sattabongkot J,Cao J,Nyunt MH,Kyaw MP,Desai SA,Miller LH,Tsuboi T,Han ET

更新日期：2016-10-19 00:00:00

abstract：:We show that the space in which scientific, technological and economic activities interplay with each other can be mathematically shaped using techniques from statistical physics of networks. We build a holistic view of the innovation system as the tri-layered network of interactions among these many activities (scien...

journal_title：Scientific reports

authors： Pugliese E,Cimini G,Patelli A,Zaccaria A,Pietronero L,Gabrielli A

更新日期：2019-11-11 00:00:00

abstract：:Adult stem cells are considered promising candidates for cellular therapies due to their capacity to differentiate and self-renew. Differentiation leads to changes in the metabolism, structure, and gene expression patterns of cells. Hedgehog is one of the pathways that is involved in the enhancement of osteogenesis an...

journal_title：Scientific reports

authors： Shigunov P,Balvedi LT,Santos MDM,Herai RH,de Aguiar AM,Dallagiovanna B

更新日期：2018-05-30 00:00:00

abstract：:The innate and adaptive immune systems fail to control HCV infection in the majority of infected individuals. HCV is an ssRNA virus, which suggests a role for Toll-like receptors (TLRs) 7 and 8 in initiating the anti-viral response. Here we demonstrate that HCV genomic RNA harbours specific sequences that initiate an ...

journal_title：Scientific reports

authors： Zhang Y,El-Far M,Dupuy FP,Abdel-Hakeem MS,He Z,Procopio FA,Shi Y,Haddad EK,Ancuta P,Sekaly RP,Said EA

更新日期：2016-07-07 00:00:00

abstract：:Valproic acid (VPA) is a drug commonly used for epileptic seizure control. Recently, it has been shown that VPA alters the activation of several immune cells, including Natural Killer (NK) cells, which play an important role in the containment of viruses and intracellular bacteria. Although VPA can increase susceptibi...

journal_title：Scientific reports

authors： Soria-Castro R,Chávez-Blanco AD,García-Pérez BE,Wong-Baeza I,Flores-Mejía R,Flores-Borja F,Estrada-Parra S,Estrada-García I,Serafín-López J,Chacón-Salinas R

更新日期：2020-10-20 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:Super-Planckian near-field radiative heat transfer allows effective heat transfer between a hot and a cold body to increase beyond the limits long known for black bodies. Until present, experimental techniques to measure the radiative heat flow relied on steady-state systems. Here, we present a dynamic measurement app...

journal_title：Scientific reports

authors： Lang S,Sharma G,Molesky S,Kränzien PU,Jalas T,Jacob Z,Petrov AY,Eich M

更新日期：2017-10-24 00:00:00

abstract：:The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region and/or differential e...

journal_title：Scientific reports

authors： Kathuria H,Millien G,McNally L,Gower AC,Tagne JB,Cao Y,Ramirez MI

更新日期：2018-09-26 00:00:00

abstract：:Magnetic carboxyl functional nanoporous polymer (MCFNP) was chemically fabricated by incorporation of magnetic Fe3O4 precursor into the carboxyl functional nanoporous polymer (CFNP). The as-synthesized MCFNP was characterized and used as an adsorbent for rapid adsorption removal of methylene blue (MB) from wastewater....

journal_title：Scientific reports

authors： Su H,Li W,Han Y,Liu N

更新日期：2018-04-25 00:00:00

abstract：:p-Alkoxyphenols (AOPs) are a class of ethers that are widely used in industrial and agricultural productions and daily necessities. p-Phenoxyphenol (PhOP) and p-pentyloxyphenol (PeOP) belong to this class and have been reported to be estrogenic in vitro. However, their in vivo estrogenic activities have rarely been of...

journal_title：Scientific reports

authors： Wang Y,Xiao H,Yang L,Jia X,Guo X,Zhang Z

更新日期：2020-10-14 00:00:00

abstract：:Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer's disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that impact microvascular network morphology as well as endothelial cell biol...

journal_title：Scientific reports

authors： Sailem HZ,Al Haj Zen A

更新日期：2020-08-14 00:00:00