Verification of radiodynamic therapy by medical linear accelerator using a mouse melanoma tumor model.

abstract：:Many systems biology studies lack context-relevant data and as a consequence the predictive capabilities can be limited in developing targeted cancer therapeutics. Production of colon crypt in vitro is ideal for studying colon systems biology. This report presents the first production of, to our knowledge, physiologic...

journal_title：Scientific reports

authors： Tan CW,Hirokawa Y,Burgess AW

更新日期：2015-06-18 00:00:00

abstract：:Micron-scale droplets isolated by an immiscible liquid can provide miniaturised reaction vessels which can be manipulated in microfluidic networks, and has seen a rapid growth in development. In many experiments, the precise volume of these microdroplets is a critical parameter which can be influenced by many external...

journal_title：Scientific reports

authors： Crawford DF,Smith CA,Whyte G

更新日期：2017-09-05 00:00:00

abstract：:Equine athletes have a pattern of exercise which is analogous to human athletes and the cardiovascular risks in both species are similar. Both species have a propensity for atrial fibrillation (AF), which is challenging to detect by ECG analysis when in paroxysmal form. We hypothesised that the proarrhythmic backgroun...

journal_title：Scientific reports

authors： Alexeenko V,Fraser JA,Bowen M,Huang CL,Marr CM,Jeevaratnam K

更新日期：2020-04-22 00:00:00

abstract：:Patients with end stage renal disease (ESRD) suffer high mortality from arrhythmias linked to fibrosis, but are contraindicated to late gadolinium enhancement magnetic resonance imaging (MRI). We present a quantitative method for gadolinium-free cardiac fibrosis imaging using magnetization transfer (MT) weighted MRI, ...

journal_title：Scientific reports

authors： Stromp TA,Spear TJ,Holtkamp RM,Andres KN,Kaine JC,Alghuraibawi WH,Leung SW,Fornwalt BK,Vandsburger MH

更新日期：2018-11-19 00:00:00

abstract：:BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstream Smad signaling pathway. FecB mutation, regarded as a loss of function mutation...

journal_title：Scientific reports

authors： Kumar S,Punetha M,Jose B,Bharati J,Khanna S,Sonwane A,Green JA,Whitworth K,Sarkar M

更新日期：2020-11-24 00:00:00

abstract：:Improving feed efficiency (FE) is a major goal of pig breeding, reducing production costs and providing sustainability to the pig industry. Reliable predictors for FE could assist pig producers. We carried out untargeted blood metabolite profiling in uncastrated males from Danbred Duroc (n = 59) and Danbred Landrace (...

journal_title：Scientific reports

authors： Carmelo VAO,Banerjee P,da Silva Diniz WJ,Kadarmideen HN

更新日期：2020-01-14 00:00:00

abstract：:Sickle cell anaemia (SCA) is characterized by reduced red blood cell (RBC) deformability and nitric oxide (NO) bioavailability. The aim of the study was to investigate whether exercise might affect these parameters in SCA. SCA patients and healthy controls (AA) performed an acute submaximal exercise test until subject...

journal_title：Scientific reports

authors： Grau M,Jerke M,Nader E,Schenk A,Renoux C,Collins B,Dietz T,Bizjak DA,Joly P,Bloch W,Connes P,Prokop A

更新日期：2019-08-14 00:00:00

abstract：:Alpha synuclein (α-syn) is a central player in neurodegeneration, but the mechanisms triggering its pathology are not fully understood. Here we found that α-syn is a highly efficient substrate for arginyltransferase ATE1 and is arginylated in vivo by a novel mid-chain mechanism that targets the acidic side chains of E...

journal_title：Scientific reports

authors： Wang J,Han X,Leu NA,Sterling S,Kurosaka S,Fina M,Lee VM,Dong DW,Yates JR 3rd,Kashina A

更新日期：2017-09-12 00:00:00

abstract：:We present combined in situ X-ray diffraction and high-speed imaging to monitor the phase evolution upon cyclic rapid laser heating and cooling mimicking the direct energy deposition of Ti-6Al-4V in real time. Additive manufacturing of the industrially relevant alloy Ti-6Al-4V is known to create a multitude of phases ...

journal_title：Scientific reports

authors： Kenel C,Grolimund D,Li X,Panepucci E,Samson VA,Sanchez DF,Marone F,Leinenbach C

更新日期：2017-11-27 00:00:00

abstract：:Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl substituents (BODIPY-CN) has been tethered to the 5'-end of the 15-m...

journal_title：Scientific reports

authors： Deore PS,Soldatov DV,Manderville RA

更新日期：2018-11-15 00:00:00

abstract：:Ricco's area (the largest area of visual space in which stimulus area and intensity are inversely proportional at threshold) has previously been hypothesised to be a result of centre/surround antagonism in retinal ganglion cell receptive fields, but recent evidence suggests a sizeable cortical contribution. Here, Ricc...

journal_title：Scientific reports

authors： Je S,Ennis FA,Woodhouse JM,Sengpiel F,Redmond T

更新日期：2018-03-01 00:00:00

abstract：:Non-classical crystallisation (NCC) pathways are widely accepted, however there is conflicting evidence regarding the intermediate stages of crystallisation, how they manifest and further develop into crystals. Evidence from direct observations is especially lacking for small organic molecules, as distinguishing these...

journal_title：Scientific reports

authors： Cookman J,Hamilton V,Hall SR,Bangert U

更新日期：2020-11-05 00:00:00

abstract：:The development of scalable synthesis techniques for optically transparent, electrically conductive coatings is in great demand due to the constantly increasing market price and limited resources of indium for indium tin oxide (ITO) materials currently applied in most of the optoelectronic devices. This work pioneers ...

journal_title：Scientific reports

authors： Mohl M,Dombovari A,Vajtai R,Ajayan PM,Kordas K

更新日期：2015-09-03 00:00:00

abstract：:Spermatogenesis in the mouse has been extensively studied for decades. Previous methods, such as histological staining or bulk transcriptome analysis, either lacked resolution at the single-cell level or were focused on a very narrowly defined set of factors. Here, we present the first comprehensive, unbiased single-c...

journal_title：Scientific reports

authors： Lukassen S,Bosch E,Ekici AB,Winterpacht A

更新日期：2018-04-25 00:00:00

abstract：:Lipid droplet (LD), a multi-functional organelle, is often found to associate with other cellular membranous structures and vary in size in a given cell, which may be related to their functional diversity. Here we established a method to separate LD subpopulations from isolated CHO K2 LDs into three different size cat...

journal_title：Scientific reports

authors： Zhang S,Wang Y,Cui L,Deng Y,Xu S,Yu J,Cichello S,Serrero G,Ying Y,Liu P

更新日期：2016-07-08 00:00:00

abstract：:Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and half-life. Without manipulating the physicochemical properties of nanoparticles with considering their biointerference, attaining effective treatment protocols is impossible. For this reason, protein corona evolution and b...

journal_title：Scientific reports

authors： Tekie FSM,Hajiramezanali M,Geramifar P,Raoufi M,Dinarvand R,Soleimani M,Atyabi F

更新日期：2020-06-15 00:00:00

abstract：:Anatase TiO2 nanoparticles with exposed {001} facets were synthesized from Ti powder via a sequential hydrothermal reaction process. At the first-step hydrothermal reaction, H-titanate nanowires were obtained in NaOH solution with Ti powder, and at second-step hydrothermal reaction, anatase TiO2 nanoparticles with exp...

journal_title：Scientific reports

authors： Chu L,Qin Z,Yang J,Li X

更新日期：2015-07-20 00:00:00

abstract：:Treatment of azo dye effluents has received increasing concerns over the years due to their potential harms to natural environment and human health. The present study described the degrading ability of the as-synthesized crystalline Al-Cu alloys for removal of high-concentration Acid Scarlet 3R in alkaline aqueous sol...

journal_title：Scientific reports

authors： Zhang L,Gao X,Zhang Z,Zhang M,Cheng Y,Su J

更新日期：2016-08-18 00:00:00

abstract：:Species are chronically exposed to ionizing radiation, a natural phenomenon which can be enhanced by human activities. The induced toxicity mechanisms still remain unclear and seem depending on the mode of exposure, i.e. acute and chronic. To better understand these phenomena, studies need to be conducted both at the ...

journal_title：Scientific reports

authors： Dubois C,Lecomte C,Ruys SPD,Kuzmic M,Della-Vedova C,Dubourg N,Galas S,Frelon S

更新日期：2018-07-27 00:00:00

abstract：:The non-invasive high-resolution spatial mapping of cell metabolism within tissues could provide substantial advancements in assessing the efficacy of stem cell therapy and understanding tissue development. Here, using two-photon excited fluorescence microscopy, we elucidate the relationships among endogenous cell flu...

journal_title：Scientific reports

authors： Quinn KP,Sridharan GV,Hayden RS,Kaplan DL,Lee K,Georgakoudi I

更新日期：2013-12-05 00:00:00

abstract：:We report abnormal magnetic field effects on electrogenerated chemiluminescence (MFEECL) based on triplet emission from the Ru(bpy)3Cl2-TPrA electrochemical system: the appearance of MFEECL after magnetic field ceases. In early studies the normal MFEECL have been observed from electrochemical systems during the applic...

journal_title：Scientific reports

authors： Pan H,Shen Y,Wang H,He L,Hu B

更新日期：2015-03-16 00:00:00

abstract：:Present study focuses on rainfall over Western Ghats (WG), a complex topographic region (elevation > 500 m) of India to evaluate and to better understand the satellite behavior in contrast with a flat region (FR) (elevation < 500 m) of central India from 1998 to 2016 using the combinatory data sets of TMPA and IMERG (...

journal_title：Scientific reports

authors： Thakur MK,Kumar TVL,Koteswara Rao K,Barbosa H,Rao VB

更新日期：2019-10-30 00:00:00

abstract：:We fabricate high-performance, flexible, transparent electrochromic (EC) films and thin film heaters (TFHs) on an ITO/Cu/ITO (ICI) multilayer electrode prepared by continuous roll-to-roll (RTR) sputtering of ITO and Cu targets. The RTR-sputtered ICI multilayer on a 700 mm wide PET substrate at room temperature exhibit...

journal_title：Scientific reports

authors： Park SH,Lee SM,Ko EH,Kim TH,Nah YC,Lee SJ,Lee JH,Kim HK

更新日期：2016-09-22 00:00:00

abstract：:This present paper was focused on the manufacture of activated carbon (AC) and its application in the electrokinetic remediation (EKR) technology on removal of the heavy metals (HMs) from the municipal solid waste incineration fly ash. AC was produced from Neosinocalamus affinis (NF) by chemical activation with H3PO4 ...

journal_title：Scientific reports

authors： Liu K,Huang T,Huang X,Yu L,Muhammad F,Jiao B,Li D

更新日期：2016-12-21 00:00:00

abstract：:Understanding how animals respond to injury and how wounds heal remains a challenge. These questions can be addressed using genetically tractable animals, including the nematode Caenorhabditis elegans. Given its small size, the current methods for inflicting wounds in a controlled manner are demanding. To facilitate a...

journal_title：Scientific reports

authors： Belougne J,Ozerov I,Caillard C,Bedu F,Ewbank JJ

更新日期：2020-02-27 00:00:00

abstract：:Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. HFMD outbreaks and reported cases have sharply increased in China since 2008. Epidemiological and clinical data of HFMD cases reported in Henan Province were collected from 2008 to 2013. Clinical specimens were obtained from a ...

journal_title：Scientific reports

authors： Huang X,Wei H,Wu S,Du Y,Liu L,Su J,Xu Y,Wang H,Li X,Wang Y,Liu G,Chen W,Klena JD,Xu B

更新日期：2015-03-10 00:00:00

abstract：:The self-organisation of void and gas bubbles in solids into superlattices is an intriguing nanoscale phenomenon. Despite the discovery of these lattices 45 years ago, the atomistics behind the ordering mechanisms responsible for the formation of these nanostructures are yet to be fully elucidated. Here we report on t...

journal_title：Scientific reports

authors： Harrison RW,Greaves G,Hinks JA,Donnelly SE

更新日期：2017-08-10 00:00:00

abstract：:The ultimate goal of epileptology is the complete abolishment of epileptic seizures. This might be achieved by a system that predicts seizure onset combined with a system that interferes with the process that leads to the onset of a seizure. Seizure prediction remains, as of yet, unresolved in absence-epilepsy, due to...

journal_title：Scientific reports

authors： Maksimenko VA,van Heukelum S,Makarov VV,Kelderhuis J,Lüttjohann A,Koronovskii AA,Hramov AE,van Luijtelaar G

更新日期：2017-05-29 00:00:00

abstract：:Olive (Olea europaea L.) is one of the most economically and historically important fruit crops worldwide. Genetic progress for valuable agronomic traits has been slow in olive despite its importance and benefits. Advances in next generation sequencing technologies provide inexpensive and highly reproducible genotypin...

journal_title：Scientific reports

authors： Kaya HB,Akdemir D,Lozano R,Cetin O,Sozer Kaya H,Sahin M,Smith JL,Tanyolac B,Jannink JL

更新日期：2019-12-10 00:00:00

abstract：:Antimonite [Sb(III)]-oxidizing bacteria can transform the toxic Sb(III) into the less toxic antimonate [Sb(V)]. Recently, the cytoplasmic Sb(III)-oxidase AnoA and the periplasmic arsenite [As(III)] oxidase AioAB were shown to responsible for bacterial Sb(III) oxidation, however, disruption of each gene only partially ...

journal_title：Scientific reports

authors： Li J,Yang B,Shi M,Yuan K,Guo W,Wang Q,Wang G

更新日期：2017-03-02 00:00:00