A 5'-BODIPY End-label for Monitoring DNA Duplex-Quadruplex Exchange.

abstract：:In this report, we investigate the stabilization of saddle fixed points in coupled oscillators where individual oscillators exhibit the saddle fixed points. The coupled oscillators may have two structurally different types of suppressed states, namely amplitude death and oscillation death. The stabilization of saddle ...

journal_title：Scientific reports

authors： Rakshit S,Bera BK,Majhi S,Hens C,Ghosh D

更新日期：2017-04-05 00:00:00

abstract：:We aimed to analyze the associations of bone mineral density (BMD) of femoral heads, age and gender, and compare the differences in BMD between fracture side and non-fracture side by "3D Spine Exam Analysis" module in QCT Pro software. In this study, we identified patients who had undergone quantitative computed tomog...

journal_title：Scientific reports

authors： Li X,Xu Y,Lin W,Fan Y

更新日期：2020-08-03 00:00:00

abstract：:Since the introduction of leukemia-type induction therapies for T-cell lymphoblastic lymphoma (T-LBL), improvements in the long-term outcomes of T-LBL have been reported. However, indications for and the appropriate timing of hematopoietic stem cell transplantation (HSCT) have not yet been established. Therefore, we p...

journal_title：Scientific reports

authors： Morita-Fujita M,Arai Y,Yoshioka S,Ishikawa T,Kanda J,Kondo T,Akasaka T,Ueda Y,Imada K,Moriguchi T,Yago K,Kitano T,Yonezawa A,Nohgawa M,Takaori-Kondo A,Kyoto Stem Cell Transplantation Group (KSCTG).

更新日期：2020-12-08 00:00:00

abstract：:PDCD4, the protein encoded by the tumor suppressor gene PDCD4 (programmed cell death 4) has been implicated in the control of cellular transcription and translation by modulating the activity of specific transcription factors and suppressing the translation of mRNAs with structured 5'-UTRs. Most studies of human PDCD4...

journal_title：Scientific reports

authors： Haas A,Nilges BS,Leidel SA,Klempnauer KH

更新日期：2020-02-17 00:00:00

abstract：:A soil remediation method based on magnetic beneficiation is reported. A new magnetic solid chelator powder, FS@IDA (core-shell Fe3O4@SiO2 nanoparticles coated with iminodiacetic acid chelators), was used as a reactive magnetic carrier to selectively capture non-magnetic heavy metals in soil by chelation and removal b...

journal_title：Scientific reports

authors： Fan L,Song J,Bai W,Wang S,Zeng M,Li X,Zhou Y,Li H,Lu H

更新日期：2016-02-16 00:00:00

abstract：:With about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte nucleus. How viral cccDNA gene expression is regulated by its chromatin structure; more importa...

journal_title：Scientific reports

authors： Alarcon V,Hernández S,Rubio L,Alvarez F,Flores Y,Varas-Godoy M,De Ferrari GV,Kann M,Villanueva RA,Loyola A

更新日期：2016-05-13 00:00:00

abstract：:15-lipoxygenase is involved in the generation of specialized pro-resolving lipid mediators that play essential roles in resolution and inflammatory responses. Here, we investigated anti-inflammatory role of Alox15 in skin homeostasis. We demonstrated that knockout (KO) of Alox15 led to hair loss and disrupted the stru...

journal_title：Scientific reports

authors： Kim SN,Akindehin S,Kwon HJ,Son YH,Saha A,Jung YS,Seong JK,Lim KM,Sung JH,Maddipati KR,Lee YH

更新日期：2018-06-11 00:00:00

abstract：:Myopic traction maculopathy (MTM) can cause vision disabilities in highly myopic eyes. This retrospective case series investigated the clinical outcomes of posterior scleral contraction (PSC) using genipin-cross-linked sclera as the material to treat MTM in highly myopic eyes. In total, 32 eyes from 29 highly myopic p...

journal_title：Scientific reports

authors： Pan AP,Wan T,Zhu SQ,Dong L,Xue AQ

更新日期：2017-02-21 00:00:00

abstract：:The repeated measurements of heart rate variability (HRV) is more relevant than a single HRV measurement in predicting patient prognosis but is less addressed previously. This prospective study aimed to investigate the association between repeated measurements of HRV and long-term mortality in chronic hemodialysis pat...

journal_title：Scientific reports

authors： Chang YM,Huang YT,Chen IL,Yang CL,Leu SC,Su HL,Kao JL,Tsai SC,Jhen RN,Shiao CC

更新日期：2020-01-21 00:00:00

abstract：:Anopheles gambiae and Aedes aegypti are perhaps the best studied mosquito species and important carriers of human malaria and arbovirus, respectively. Mosquitoes have daily rhythms in behaviors and show a wide range of activity patterns. Although Anopheles is known to be principally nocturnal and Aedes principally diu...

journal_title：Scientific reports

authors： Araujo MDS,Guo F,Rosbash M

更新日期：2020-03-19 00:00:00

abstract：:It has been a long-standing puzzle why buckled dimers of the Si(001) surface appeared symmetric below ~20 K in scanning tunneling microscopy (STM) experiments. Although such symmetric dimer images were concluded to be due to an artifact induced by STM measurements, its underlying mechanism is still veiled. Here, we de...

journal_title：Scientific reports

authors： Ren XY,Kim HJ,Niu CY,Jia Y,Cho JH

更新日期：2016-06-13 00:00:00

abstract：:Axonal injury is a common feature of central nervous system insults that culminates with the death of the affected neurons, and an irreversible loss of function. Inflammation is an important component of the neurodegenerative process, where the microglia plays an important role by releasing proinflammatory factors as ...

journal_title：Scientific reports

authors： Nadal-Nicolás FM,Galindo-Romero C,Valiente-Soriano FJ,Barberà-Cremades M,deTorre-Minguela C,Salinas-Navarro M,Pelegrín P,Agudo-Barriuso M

更新日期：2016-12-08 00:00:00

abstract：:Enhancers play a crucial role in gene regulation but the participation of enhancer transcripts (i.e. enhancer RNA, eRNAs) in regulatory systems remains unclear. We provide a computational analysis on eRNAs using genome-wide data across 12 mouse tissues. The expression of genes targeted by transcribing enhancer is posi...

journal_title：Scientific reports

authors： Cheng JH,Pan DZ,Tsai ZT,Tsai HK

更新日期：2015-07-29 00:00:00

abstract：:Several prenatal and perinatal factors have been found to be associated with developmental dyslexia (reading disorder) in alphabetic language. Given the absence of relevant studies of Chinese children, the present study tries to investigate these risk factors. A total of 45,850 students were recruited from grades thre...

journal_title：Scientific reports

authors： Liu L,Wang J,Shao S,Luo X,Kong R,Zhang X,Song R

更新日期：2016-11-07 00:00:00

abstract：:Biological sulfate-reducing bacteria (SRB) may be effective in removing toxic lead and mercury ions (Pb(II) and Hg(II)) from wet flue gas desulfurization (FGD) wastewater through anaerobic sulfite reduction. To confirm this hypothesis, a sulfite-reducing up-flow anaerobic sludge blanket reactor was set up to treat FGD...

journal_title：Scientific reports

authors： Zhang L,Lin X,Wang J,Jiang F,Wei L,Chen G,Hao X

更新日期：2016-07-26 00:00:00

abstract：:The aim of this study was to analyse postoperative haemorrhage (POH) after a total thyroidectomy and explore the possible risk factors. Records of patients receiving a total thyroidectomy were reviewed and analysed for risk factors of POH. From the 2,678 patients in this study, a total of 39 patients had POH, represen...

journal_title：Scientific reports

authors： Zhang X,Du W,Fang Q

更新日期：2017-08-01 00:00:00

abstract：:Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and neurotoxic effects, but the...

journal_title：Scientific reports

authors： Esposito G,Capoccia E,Gigli S,Pesce M,Bruzzese E,D'Alessandro A,Cirillo C,di Cerbo A,Cuomo R,Seguella L,Steardo L,Sarnelli G

更新日期：2017-08-10 00:00:00

abstract：:An accurate method to predict the mortality in the intensive care unit (ICU) patients has been required, especially in children. The aim of this study is to evaluate the value of serum anion gap (AG) for predicting mortality in pediatric ICU (PICU). We reviewed a data of 461 pediatric patients were collected on PICU a...

journal_title：Scientific reports

authors： Kim MJ,Kim YH,Sol IS,Kim SY,Kim JD,Kim HY,Kim KW,Sohn MH,Kim KE

更新日期：2017-05-03 00:00:00

abstract：:Hepcidin, a cysteine-rich peptide hormone, secreted mainly by the liver, plays a central role in iron metabolism regulation. Emerging evidence suggests that disordered iron metabolism is a risk factor for various types of diseases including cancers. However, it remains challenging to apply current mass spectrometry (M...

journal_title：Scientific reports

authors： Moghieb A,Tesfay L,Nie S,Gritsenko M,Fillmore TL,Jacobs JM,Smith RD,Torti FM,Torti SV,Shi T,Ansong C

更新日期：2019-05-13 00:00:00

abstract：:Raman microspectroscopy provides the means to obtain local orientations on polycrystalline materials at the submicrometer level. The present work demonstrates how orientation-distribution maps composed of Raman intensity distributions can be acquired on large areas of several hundreds of square micrometers. A polycrys...

journal_title：Scientific reports

authors： Schmid T,Schäfer N,Levcenko S,Rissom T,Abou-Ras D

更新日期：2015-12-17 00:00:00

abstract：:We report the synthesis of single-crystal iron germanium nanowires via chemical vapor deposition without the assistance of any catalysts. The assembly of single-crystal FeGe2 nanowires with tetragonal C16 crystal structure shows anisotropic magnetic behavior along the radial direction or the growth axial direction, wi...

journal_title：Scientific reports

authors： Tang S,Kravchenko I,Ward TZ,Zou Q,Yi J,Ma C,Chi M,Cao G,Li AP,Mandrus D,Gai Z

更新日期：2017-08-02 00:00:00

abstract：:In this paper, we explore the concept of structural Luneburg lens (SLL) as a design framework for performing dynamic structural tailoring to obtain a structural wave cloak and a structural waveguide. The SLL is a graded refractive index lens, which is realized by using a variable thickness structure defined in a thin ...

journal_title：Scientific reports

authors： Zhao L,Yu M

更新日期：2020-09-03 00:00:00

abstract：:Recent breakthrough of novel hierarchic materials, orchestrated through oriented attachment of crystal subunits, opened questions on what is the mechanism of their self-assembly. Using rutile-type TiO2, synthesized by hydrothermal reaction of Ti(IV)-butoxide in highly acidic aqueous medium, we uncovered the key proces...

journal_title：Scientific reports

authors： Jordan V,Javornik U,Plavec J,Podgornik A,Rečnik A

更新日期：2016-04-11 00:00:00

abstract：:Although re-sequencing of gene panels and mRNA expression profiling are now firmly established in clinical laboratories, in-depth proteome analysis has remained a niche technology, better suited for studying model systems rather than challenging materials such as clinical trial samples. To address this limitation, we ...

journal_title：Scientific reports

authors： Hughes CS,McConechy MK,Cochrane DR,Nazeran T,Karnezis AN,Huntsman DG,Morin GB

更新日期：2016-10-07 00:00:00

abstract：:Grading of essential hypertension according to blood pressure (BP) level may not adequately reflect clinical heterogeneity of hypertensive patients. This study was carried out to explore clinical phenotypes in essential hypertensive patients using cluster analysis. This study recruited 513 hypertensive patients and ev...

journal_title：Scientific reports

authors： Guo Q,Lu X,Gao Y,Zhang J,Yan B,Su D,Song A,Zhao X,Wang G

更新日期：2017-03-07 00:00:00

abstract：:Single-photon emission computed tomography combined with micro-CT (SPECT/μCT) imaging using Nanobodies against complement receptor of the Ig superfamily (CRIg), found on tissue macrophages such as synovial macrophages, has promising potential to visualize joint inflammation in experimental arthritis. Here, we further ...

journal_title：Scientific reports

authors： Zheng F,Perlman H,Matthys P,Wen Y,Lahoutte T,Muyldermans S,Lu S,De Baetselier P,Schoonooghe S,Devoogdt N,Raes G

更新日期：2016-10-25 00:00:00

abstract：:Amyloid-β (Aβ) deposition is known to starts decades before the onset of clinical symptoms of Alzheimer's disease (AD), however, the detailed pathophysiological processes underlying this preclinical period are not well understood. This study aimed to investigate functional network alterations in cognitively intact eld...

journal_title：Scientific reports

authors： Nakamura A,Cuesta P,Kato T,Arahata Y,Iwata K,Yamagishi M,Kuratsubo I,Kato K,Bundo M,Diers K,Fernández A,Maestú F,Ito K

更新日期：2017-07-26 00:00:00

abstract：:Conventional crystalline β-MnO2 usually exhibits poor electrochemical activities due to the narrow tunnels in its rutile-type structure. In this study, we synthesized a novel 2D β-MnO2 network with long-range order assembled by β-MnO2 nanowires and demonstrated that the novel 2D β-MnO2 network exhibits enhanced electr...

journal_title：Scientific reports

authors： Wei C,Pang H,Zhang B,Lu Q,Liang S,Gao F

更新日期：2013-01-01 00:00:00

abstract：:Miscarriage affects ~20% of pregnancies and maternal infections account for ~15% of early miscarriages. Chlamydia trachomatis (Ct) has been associated with miscarriage but the underlying mechanisms are unknown. Successful implantation requires endometrial stromal cell (ESC) decidualisation. Maintenance of pregnancy re...

journal_title：Scientific reports

authors： Giakoumelou S,Wheelhouse N,Brown J,Wade J,Simitsidellis I,Gibson D,Saunders PTK,Horner P,Entrican G,Howie SEM,Horne AW

更新日期：2017-05-17 00:00:00

abstract：:Perinatal piglet mortality is an important factor in pig production from economic and animal welfare perspectives; however, the statistical analysis of mortality is difficult because of its categorical nature. Recent studies have suggested that a binomial model for the survival of each specific piglet with a logit app...

journal_title：Scientific reports

authors： Varona L,Noguera JL,Casellas J,de Hijas MM,Rosas JP,Ibáñez-Escriche N

更新日期：2020-12-03 00:00:00