当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > Serum anion gap at admission as a predictor of mortality in the pediatric intensive care unit.

Serum anion gap at admission as a predictor of mortality in the pediatric intensive care unit.

Abstract：

:An accurate method to predict the mortality in the intensive care unit (ICU) patients has been required, especially in children. The aim of this study is to evaluate the value of serum anion gap (AG) for predicting mortality in pediatric ICU (PICU). We reviewed a data of 461 pediatric patients were collected on PICU admission. Corrected anion gap (cAG), the AG compensated for abnormal albumin levels, was significantly lower in survivors compared with nonsurvivors (p < 0.001). Multivariable logistic regression analysis identified the following variables as independent predictors of mortality; cAG (OR 1.110, 95% CI 1.06-1.17; p < 0.001), PIM3 [OR 7.583, 95% CI 1.81-31.78; p = 0.006], and PRISM III [OR 1.076, 95% CI 1.02-1.14; p = 0.008]. Comparing AUCs for mortality prediction, there were no statistically significant differences between cAG and other mortality prediction models; cAG 0.728, PIM2 0.779, PIM3 0.822, and PRISM III 0.808. The corporation of cAG to pre-existing mortality prediction models was significantly more accurate at predicting mortality than using any of these models alone. We concluded that cAG at ICU admission may be used to predict mortality in children, regardless of underlying etiology. And the incorporation of cAG to pre-existing mortality prediction models might improve predictability.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kim MJ,Kim YH,Sol IS,Kim SY,Kim JD,Kim HY,Kim KW,Sohn MH,Kim KE

doi

10.1038/s41598-017-01681-9

subject

Has Abstract

pub_date

2017-05-03 00:00:00

pages

1456

issue

1

issn

2045-2322

pii

10.1038/s41598-017-01681-9

journal_volume

7

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Paneth Cell in Adenomas of the Distal Colorectum Is Inversely Associated with Synchronous Advanced Adenoma and Carcinoma.

    abstract：:Recent studies have linked appearance of Paneth cells in colorectal adenomas to adenoma burden and male gender. However, the clinical importance of Paneth cells' associations with synchronous advanced adenoma (AA) and colorectal carcinoma (CRC) is currently unclear. We performed a comprehensive case-control study usin...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep26129

    authors： Mahon M,Xu J,Yi X,Liu X,Gao N,Zhang L

    更新日期：2016-05-18 00:00:00

  • Generation of biallelic knock-out sheep via gene-editing and somatic cell nuclear transfer.

    abstract：:Transgenic sheep can be used to achieve genetic improvements in breeds and as an important large-animal model for biomedical research. In this study, we generated a TALEN plasmid specific for ovine MSTN and transfected it into fetal fibroblast cells of STH sheep. MSTN biallelic-KO somatic cells were selected as nuclea...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep33675

    authors： Li H,Wang G,Hao Z,Zhang G,Qing Y,Liu S,Qing L,Pan W,Chen L,Liu G,Zhao R,Jia B,Zeng L,Guo J,Zhao L,Zhao H,Lv C,Xu K,Cheng W,Li H,Zhao HY,Wang W,Wei HJ

    更新日期：2016-09-22 00:00:00

  • Ripening of bananas using Bowdichia virgilioides Kunth leaves.

    abstract：:Bananas are usually ripened with calcium carbide (CaC2), a dangerous substance that can cause food poisoning. The objective was to test the empirical ripening banana method using Bowdichia virgilioides leaves compared to carbide. Ripening tests were carried out using 'Pacovan' banana fruits with B. virgilioides leaves...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-40053-3

    authors： da Costa Nascimento R,de Oliveira Freire O,Ribeiro LS,Araújo MB,Finger FL,Soares MA,Wilcken CF,Zanuncio JC,Souto Ribeiro W

    更新日期：2019-03-05 00:00:00

  • Incorporating hybrid models into lysine malonylation sites prediction on mammalian and plant proteins.

    abstract：:Protein malonylation, a reversible post-translational modification of lysine residues, is associated with various biological functions, such as cellular regulation and pathogenesis. In proteomics, to improve our understanding of the mechanisms of malonylation at the molecular level, the identification of malonylation ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-67384-w

    authors： Chung CR,Chang YP,Hsu YL,Chen S,Wu LC,Horng JT,Lee TY

    更新日期：2020-06-29 00:00:00

  • Revised role for Hfq bacterial regulator on DNA topology.

    abstract：:Hfq is a pleiotropic regulator that mediates several aspects of bacterial RNA metabolism. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, usually via its interaction with small regulatory RNA. Besides these RNA-related functions, Hfq has also been described as one of the n...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-35060-9

    authors： Malabirade A,Partouche D,El Hamoui O,Turbant F,Geinguenaud F,Recouvreux P,Bizien T,Busi F,Wien F,Arluison V

    更新日期：2018-11-14 00:00:00

  • Projecting groundwater storage changes in California's Central Valley.

    abstract：:Accurate and detailed knowledge of California's groundwater is of paramount importance for statewide water resources planning and management, and to sustain a multi-billion-dollar agriculture industry during prolonged droughts. In this study, we use water supply and demand information from California's Department of W...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-31210-1

    authors： Massoud EC,Purdy AJ,Miro ME,Famiglietti JS

    更新日期：2018-08-27 00:00:00

  • Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors.

    abstract：:Auditory neuropathy (AN) is a hearing disorder characterized by normal cochlear amplification to sound but poor temporal processing and auditory perception in noisy backgrounds. These deficits likely result from impairments in auditory neural synchrony; such dyssynchrony of the neural responses has been linked to demy...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-06600-6

    authors： Pan H,Song Q,Huang Y,Wang J,Chai R,Yin S,Wang J

    更新日期：2017-07-25 00:00:00

  • Rating knockdown of flour beetles after exposure to two insecticides as an indicator of mortality.

    abstract：:Knockdown and mortality of adults of the red flour beetle, Tribolium castaneum (Herbst) and the confused flour beetle, Tribolium confusum Jacquelin du Val, were assessed after exposure to two contact insecticides, chlorfenapyr and cyfluthrin, on a concrete surface. Individuals were rated on a scale for knockdown of ex...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-78982-z

    authors： Athanassiou CG,Kavallieratos NG,Arthur FH,Nakas CT

    更新日期：2021-01-13 00:00:00

  • Synthesis, properties and surface self-assembly of a pentanuclear cluster based on the new π-conjugated TTF-triazole ligand.

    abstract：:The new π-extended redox-active ligand with both TTF and triazole units, 6-(4,5-bis(propylthio)-1,3-dithiol-2-ylidene)-1H-[1,3]dithiolo[4',5':4,5]benzo [1,2-d] [1-3]triazole, has been successfully prepared. Based on the versatile ligand and Cu(tta)2 precursors (tta(-) = 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dion...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep25544

    authors： Cui L,Geng YF,Leong CF,Ma Q,D'Alessandro DM,Deng K,Zeng QD,Zuo JL

    更新日期：2016-05-06 00:00:00

  • Quantitative imaging of heterogeneous dynamics in drying and aging paints.

    abstract：:Drying and aging paint dispersions display a wealth of complex phenomena that make their study fascinating yet challenging. To meet the growing demand for sustainable, high-quality paints, it is essential to unravel the microscopic mechanisms underlying these phenomena. Visualising the governing dynamics is, however, ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep34383

    authors： van der Kooij HM,Fokkink R,van der Gucht J,Sprakel J

    更新日期：2016-09-29 00:00:00

  • In Vivo Near Infrared Virtual Intraoperative Surgical Photoacoustic Optical Coherence Tomography.

    abstract：:Since its first implementation in otolaryngological surgery nearly a century ago, the surgical microscope has improved the accuracy and the safety of microsurgeries. However, the microscope shows only a magnified surface view of the surgical region. To overcome this limitation, either optical coherence tomography (OCT...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep35176

    authors： Lee D,Lee C,Kim S,Zhou Q,Kim J,Kim C

    更新日期：2016-10-12 00:00:00

  • Tendons from kangaroo rats are exceptionally strong and tough.

    abstract：:Tendons must be able to withstand the forces generated by muscles and not fail. Accordingly, a previous comparative analysis across species has shown that tendon strength (i.e., failure stress) increases for larger species. In addition, the elastic modulus increases proportionally to the strength, demonstrating that t...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-44671-9

    authors： Javidi M,McGowan CP,Schiele NR,Lin DC

    更新日期：2019-06-03 00:00:00

  • A new strategy to measure intercellular adhesion forces in mature cell-cell contacts.

    abstract：:Intercellular adhesion plays a major role in tissue development and homeostasis. Yet, technologies to measure mature cell-cell contacts are not available. We introduce a methodology based on fluidic probe force microscopy to assess cell-cell adhesion forces after formation of mature intercellular contacts in cell mono...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep46152

    authors： Sancho A,Vandersmissen I,Craps S,Luttun A,Groll J

    更新日期：2017-04-10 00:00:00

  • CNS microRNA profiles: a database for cell type enriched microRNA expression across the mouse central nervous system.

    abstract：:microRNAs are short, noncoding RNAs that can regulate hundreds of targets and thus shape the expression landscape of a cell. Similar to mRNA, they often exhibit cell type enriched expression and serve to reinforce cellular identity. In tissue with high cellular complexity, such as the central nervous system (CNS), it ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-61307-5

    authors： Pomper N,Liu Y,Hoye ML,Dougherty JD,Miller TM

    更新日期：2020-03-18 00:00:00

  • Egg oil from Portunus trituberculatus alleviated obesity and regulated gut microbiota in mice.

    abstract：:Egg oil from Portunus trituberculatus (Pt-egg oil) can overcome insulin resistance resulting from abundant bioactive lipids. However, its effects on obesity and gut microbiota were unclear. Here, we evaluated whether Pt-egg oil could improve obesity and gut microbiota or not in high-fat diet feeding mice. Results exhi...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-65199-3

    authors： Hu S,Yang H,Gao X,Li S,Jiang W,Liu Y

    更新日期：2020-05-21 00:00:00

  • Microgravity inhibits decidualization via decreasing Akt activity and FOXO3a expression in human endometrial stromal cells.

    abstract：:Decidualization is characterized by the differentiation of endometrial stromal cells (eSCs), which is critical for embryo implantation and maintenance of pregnancy. In the present study, we investigated the possible effect of simulated microgravity (SM) on the process of proliferation and in vitro decidualization usin...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-48580-9

    authors： Cho HJ,Baek MO,Khaliq SA,Chon SJ,Son KH,Lee SH,Yoon MS

    更新日期：2019-08-20 00:00:00

  • Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.

    abstract：:More than a hundred different Transthyretin (TTR) mutations are associated with fatal systemic amyloidoses. They destabilize the protein tetrameric structure and promote the extracellular deposition of TTR as pathological amyloid fibrils. So far, only mutations R104H and T119M have been shown to stabilize significantl...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep44709

    authors： Sant'Anna R,Almeida MR,Varejāo N,Gallego P,Esperante S,Ferreira P,Pereira-Henriques A,Palhano FL,de Carvalho M,Foguel D,Reverter D,Saraiva MJ,Ventura S

    更新日期：2017-03-24 00:00:00

  • TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling.

    abstract：:Transforming growth factor-β (TGF-β) signaling plays a key role in progression and metastasis of HCC. This study was undertaken to gain the proof of concept of a small-molecule inhibitor of TGF-β type I receptor kinase, EW-7197 as a potent anti-cancer therapy for HCC. We identified tissue inhibitors of metalloproteina...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep16492

    authors： Park SA,Kim MJ,Park SY,Kim JS,Lim W,Nam JS,Yhong Sheen Y

    更新日期：2015-11-09 00:00:00

  • Long non-coding RNA PARTICLE bridges histone and DNA methylation.

    abstract：:PARTICLE (Gene PARTICL- 'Promoter of MAT2A-Antisense RadiaTion Induced Circulating LncRNA) expression is transiently elevated following low dose irradiation typically encountered in the workplace and from natural sources. This long non-coding RNA recruits epigenetic silencers for cis-acting repression of its neighbour...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-01875-1

    authors： O'Leary VB,Hain S,Maugg D,Smida J,Azimzadeh O,Tapio S,Ovsepian SV,Atkinson MJ

    更新日期：2017-05-11 00:00:00

  • Composite Membranes of Recombinant Silkworm Antimicrobial Peptide and Poly (L-lactic Acid) (PLLA) for biomedical application.

    abstract：:Antimicrobial peptides, produced by innate immune system of hosts in response to invading pathogens, are capable of fighting against a spectrum of bacteria, viruses, fungi, parasites and cancer cells. Here, a recombinant silkworm AMP Bmattacin2 from heterologous expression is studied, indicating a broad spectrum of an...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep31149

    authors： Li Z,Liu X,Li Y,Lan X,Leung PH,Li J,Li G,Xie M,Han Y,Lin X

    更新日期：2016-08-09 00:00:00

  • Mineral dust aerosols promote the formation of toxic nitropolycyclic aromatic compounds.

    abstract：:Atmospheric nitrated polycyclic aromatic hydrocarbons (NPAHs), which have been shown to have adverse health effects such as carcinogenicity, are formed in part through nitration reactions of their parent polycyclic aromatic hydrocarbons (PAHs) in the atmosphere. However, little is known about heterogeneous nitration r...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep24427

    authors： Kameda T,Azumi E,Fukushima A,Tang N,Matsuki A,Kamiya Y,Toriba A,Hayakawa K

    更新日期：2016-04-14 00:00:00

  • The expression and function of miR-424 in infantile skin hemangioma and its mechanism.

    abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

    journal_title：Scientific reports

    pub_type： 临床试验,杂志文章

    doi：10.1038/s41598-017-10674-7

    authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

    更新日期：2017-09-19 00:00:00

  • Perioperative multidisciplinary implementation enhancing recovery after hip arthroplasty in geriatrics with preoperative chronic hypoxaemia.

    abstract：:We investigated risk factors for postoperative serious adverse events (SAEs) in elderly patients with preoperative chronic hypoxaemia undergone total hip arthroplasty (THA) or hemiarthroplasty and performed an implementation to modify and improve clinical outcome. A retrospective medical record review was performed to...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-55607-8

    authors： He L,Zhang R,Yin J,Zhang H,Bu W,Wang F,Zhang F

    更新日期：2019-12-16 00:00:00

  • Solar-mediated thermo-electrochemical oxidation of sodium dodecyl benzene sulfonate by modulating the effective oxidation potential and pathway for green remediation of wastewater.

    abstract：:To match the relentless pursuit of three research hot points - efficient solar utilization, green and sustainable remediation of wastewater and advanced oxidation processes, solar-mediated thermo-electrochemical oxidation of surfactant was proposed and developed for green remediation of surfactant wastewater. The sola...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep44683

    authors： Gu D,Gao S,Jiang T,Wang B

    更新日期：2017-03-15 00:00:00

  • The Replication-Transmission Relativity Theory for Multiscale Modelling of Infectious Disease Systems.

    abstract：:It is our contention that for multiscale modelling of infectious disease systems to evolve and expand in scope, it needs to be founded on a theory. Such a theory would improve our ability to describe infectious disease systems in terms of their scales and levels of organization, and their inter-relationships. In this ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-52820-3

    authors： Garira W

    更新日期：2019-11-08 00:00:00

  • Genomic signatures of local adaptation reveal source-sink dynamics in a high gene flow fish species.

    abstract：:Understanding source-sink dynamics is important for conservation management, particularly when climatic events alter species' distributions. Following a 2011 'marine heatwave' in Western Australia, we observed high recruitment of the endemic fisheries target species Choerodon rubescens, towards the cooler (southern) e...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-09224-y

    authors： Cure K,Thomas L,Hobbs JA,Fairclough DV,Kennington WJ

    更新日期：2017-08-17 00:00:00

  • Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum.

    abstract：:Helicobacter pullorum is an avian bacterium that causes gastroenteritis, intestinal bowel and hepatobiliary diseases in humans. Although H. pullorum has been shown to activate the mammalian innate immunity with release of nitric oxide (NO), the proteins that afford protection against NO and reactive nitrogen species (...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-10375-1

    authors： Parente MR,Forte E,Falabella M,Boneca IG,Teixeira M,Giuffrè A,Saraiva LM

    更新日期：2017-08-30 00:00:00

  • Novel Polymer-Free Everolimus-Eluting Stent Fabricated using Femtosecond Laser Improves Re-endothelialization and Anti-inflammation.

    abstract：:The aim of this study was to fabricate a novel polymer-free everolimus-eluting stent with nanostructure using a femtosecond laser (FSL). The stent were coated with everolimus (EVL) using FSL and electrospinning processes. The surface was rendered hydrophobic, which negatively affected both platelet adhesion (82.1%) an...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-25629-9

    authors： Bae IH,Jeong MH,Lim KS,Park DS,Shim JW,Park JK,Oh KH,Jin MR,Sim DS

    更新日期：2018-05-09 00:00:00

  • Optimal architectures for long distance quantum communication.

    abstract：:Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥ 1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep20463

    authors： Muralidharan S,Li L,Kim J,Lütkenhaus N,Lukin MD,Jiang L

    更新日期：2016-02-15 00:00:00

  • Beatquency domain and machine learning improve prediction of cardiovascular death after acute coronary syndrome.

    abstract：:Frequency domain measures of heart rate variability (HRV) are associated with adverse events after a myocardial infarction. However, patterns in the traditional frequency domain (measured in Hz, or cycles per second) may capture different cardiac phenomena at different heart rates. An alternative is to consider freque...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep34540

    authors： Liu Y,Scirica BM,Stultz CM,Guttag JV

    更新日期：2016-10-06 00:00:00