Assessing effects from four years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle, 2013-2017.

Abstract:

:The objective was to measure the association between badger culling and bovine tuberculosis (TB) incidents in cattle herds in three areas of England between 2013-2017 (Gloucestershire and Somerset) and 2015-2017 (Dorset). Farming industry-selected licensed culling areas were matched to comparison areas. A TB incident was detection of new Mycobacterium bovis infection (post-mortem confirmed) in at least one animal in a herd. Intervention and comparison area incidence rates were compared in central zones where culling was conducted and surrounding buffer zones, through multivariable Poisson regression analyses. Central zone incidence rates in Gloucestershire (Incidence rate ratio (IRR) 0.34 (95% CI 0.29 to 0.39, p < 0.001) and Somerset (IRR 0.63 (95% CI 0.58 to 0.69, p < 0.001) were lower and no different in Dorset (IRR 1.10, 95% CI 0.96 to 1.27, p = 0.168) than comparison central zone rates. The buffer zone incidence rate was lower for Gloucestershire (IRR 0.64, 95% CI 0.58 to 0.70, p < 0.001), no different for Somerset (IRR 0.97, 95% CI 0.80 to 1.16, p = 0.767) and lower for Dorset (IRR 0.45, 95% CI 0.37 to 0.54, p < 0.001) than comparison buffer zone rates. Industry-led culling was associated with reductions in cattle TB incidence rates after four years but there were variations in effects between areas.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Downs SH,Prosser A,Ashton A,Ashfield S,Brunton LA,Brouwer A,Upton P,Robertson A,Donnelly CA,Parry JE

doi

10.1038/s41598-019-49957-6

subject

Has Abstract

pub_date

2019-10-11 00:00:00

pages

14666

issue

1

issn

2045-2322

pii

10.1038/s41598-019-49957-6

journal_volume

9

pub_type

杂志文章
  • n and p type character of single molecule diodes.

    abstract::Looking for single molecule electronic devices, we have investigated the charge transport properties of individual tetra-phenylporphyrin molecules on different substrates by ultrahigh-vacuum scanning tunneling microscopy and spectroscopy and by first-principles calculations. The tetra-phenylporphyrins with a Co atom (...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08350

    authors: Zoldan VC,Faccio R,Pasa AA

    更新日期:2015-02-10 00:00:00

  • Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans.

    abstract::Mitochondria play critical roles in meeting cellular energy demand, in cell death, and in reactive oxygen species (ROS) and stress signaling. Most Caenorhabditis elegans loss-of-function (lf) mutants in nuclear-encoded components of the respiratory chain are non-viable, emphasizing the importance of respiratory functi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29695

    authors: Wojtovich AP,Wei AY,Sherman TA,Foster TH,Nehrke K

    更新日期:2016-07-21 00:00:00

  • Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice.

    abstract::Fatty infiltration in muscle is often observed in patients with sizable rotator cuff tear (RCT) and is thought to be an irreversible event that significantly compromises muscle plasticity and contraction strength. These changes in the mechanical properties of the affected muscle render surgical repair of RCT highly fo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41552

    authors: Shirasawa H,Matsumura N,Shimoda M,Oki S,Yoda M,Tohmonda T,Kanai Y,Matsumoto M,Nakamura M,Horiuchi K

    更新日期:2017-01-31 00:00:00

  • Application of biosurfactant from Bacillus subtilis C9 for controlling cladoceran grazers in algal cultivation systems.

    abstract::Open algal cultivation platforms often suffer crop losses to herbivorous grazers that have potential to devastate biomass production within a few days. While a number of studies suggest synthetic chemicals as control agents for voracious algal grazers, environmental and safety concerns associated with the use of these...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23535-8

    authors: Yun JH,Cho DH,Lee B,Kim HS,Chang YK

    更新日期:2018-03-29 00:00:00

  • Influence of Roasting Condition on Flavor Profile of Sunflower Seeds: A flavoromics approach.

    abstract::Sunflower see/ds (Helianthus annuus L.) were roasted in an electric forced air oven for 15, 30, 45, and 60 min at 125, 135 and 145 °C. The effect of temperature and time on the flavor profile of the samples were evaluated by headspace solid-phase microextraction coupled with gas chromatography-mass spectroscopy (HS-SP...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47811-3

    authors: Guo S,Na Jom K,Ge Y

    更新日期:2019-08-05 00:00:00

  • Two-dimensional carbon compounds derived from graphyne with chemical properties superior to those of graphene.

    abstract::Computational studies considering both thermodynamic and kinetic aspects revealed that graphyne, a carbon material that has recently been of increasing interest, favours unprecedented homogeneous "in-plane" addition reactions. The addition of dichlorocarbene to the C(sp)-C(sp) bond, a site with outstanding regioselect...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01271

    authors: Zheng JJ,Zhao X,Zhao Y,Gao X

    更新日期:2013-01-01 00:00:00

  • Simultaneous MR imaging for tissue engineering in a rat model of stroke.

    abstract::In situ tissue engineering within a stroke cavity is gradually emerging as a novel therapeutic paradigm. Considering the varied lesion topology within each subject, the placement and distribution of cells within the lesion cavity is challenging. The use of multiple cell types to reconstruct damaged tissue illustrates ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep14597

    authors: Nicholls FJ,Ling W,Ferrauto G,Aime S,Modo M

    更新日期:2015-09-30 00:00:00

  • An oxytocin-dependent social interaction between larvae and adult C. elegans.

    abstract::Oxytocin has a conserved role in regulating animal social behaviour including parental-offspring interactions. Recently an oxytocin-like neuropeptide, nematocin, and its cognate receptors have been identified in the nematode Caenorhabditis elegans. We provide evidence for a pheromone signal produced by C. elegans larv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09350-7

    authors: Scott E,Hudson A,Feist E,Calahorro F,Dillon J,de Freitas R,Wand M,Schoofs L,O'Connor V,Holden-Dye L

    更新日期:2017-08-31 00:00:00

  • Exome sequencing in the knockin mice generated using the CRISPR/Cas system.

    abstract::Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other genes, which could...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34703

    authors: Nakajima K,Kazuno AA,Kelsoe J,Nakanishi M,Takumi T,Kato T

    更新日期:2016-10-04 00:00:00

  • Principles of dynamical modularity in biological regulatory networks.

    abstract::Intractable diseases such as cancer are associated with breakdown in multiple individual functions, which conspire to create unhealthy phenotype-combinations. An important challenge is to decipher how these functions are coordinated in health and disease. We approach this by drawing on dynamical systems theory. We pos...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep21957

    authors: Deritei D,Aird WC,Ercsey-Ravasz M,Regan ER

    更新日期:2016-03-16 00:00:00

  • Quantum phases in circuit QED with a superconducting qubit array.

    abstract::Circuit QED on a chip has become a powerful platform for simulating complex many-body physics. In this report, we realize a Dicke-Ising model with an antiferromagnetic nearest-neighbor spin-spin interaction in circuit QED with a superconducting qubit array. We show that this system exhibits a competition between the c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04083

    authors: Zhang Y,Yu L,Liang JQ,Chen G,Jia S,Nori F

    更新日期:2014-02-13 00:00:00

  • The relationship between alertness and spatial attention under simulated shiftwork.

    abstract::Higher and lower levels of alertness typically lead to a leftward and rightward bias in attention, respectively. This relationship between alertness and spatial attention potentially has major implications for health and safety. The current study examined alertness and spatial attention under simulated shiftworking co...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/s41598-020-71800-6

    authors: Chandrakumar D,Dorrian J,Banks S,Keage HAD,Coussens S,Gupta C,Centofanti SA,Stepien JM,Loetscher T

    更新日期:2020-09-11 00:00:00

  • An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum.

    abstract::Establishing robust genome engineering methods in the malarial parasite, Plasmodium falciparum, has the potential to substantially improve the efficiency with which we gain understanding of this pathogen's biology to propel treatment and elimination efforts. Methods for manipulating gene expression and engineering the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77644-4

    authors: Nasamu AS,Falla A,Pasaje CFA,Wall BA,Wagner JC,Ganesan SM,Goldfless SJ,Niles JC

    更新日期:2021-01-11 00:00:00

  • Maternal body mass index moderates antenatal depression effects on infant birthweight.

    abstract::Obesity and depression are two common medical problems that pregnant women present with in antenatal care. Overweight and obesity at the beginning of the pregnancy, and excessive weight gain during pregnancy, are independent explanatory variables for fetal birthweight and independent risk factors for giving birth to a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42360-1

    authors: Petursdottir Maack H,Skalkidou A,Sjöholm A,Eurenius-Orre K,Mulic-Lutvica A,Wikström AK,Sundström Poromaa I

    更新日期:2019-04-17 00:00:00

  • Tropical protected areas reduced deforestation carbon emissions by one third from 2000-2012.

    abstract::Tropical deforestation is responsible for around one tenth of total anthropogenic carbon emissions, and tropical protected areas (PAs) that reduce deforestation can therefore play an important role in mitigating climate change and protecting biodiversity and ecosystem services. While the effectiveness of PAs in reduci...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14467-w

    authors: Bebber DP,Butt N

    更新日期:2017-10-25 00:00:00

  • Nanofiber network with adjustable nanostructure controlled by PVP content for an excellent microwave absorption.

    abstract::Carbon nanofibers were widely utilized to improve microwave absorption properties since they are a promising lightweight candidate. Adjustable conductive nanostructures of carbon nanofibers were synthesized by electrospinning technique. The conductive network is controlled by the polyvinyl pyrrolidone (PVP) content du...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-38899-8

    authors: Lv J,Gu W,Cui X,Dai S,Zhang B,Ji G

    更新日期:2019-03-12 00:00:00

  • Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.

    abstract::Successful tissue repair requires the activities of myeloid cells such as monocytes and macrophages that guide the progression of inflammation and healing outcome. Immunoregenerative materials leverage the function of endogenous immune cells to orchestrate complex mechanisms of repair; however, a deeper understanding ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00477-1

    authors: Olingy CE,San Emeterio CL,Ogle ME,Krieger JR,Bruce AC,Pfau DD,Jordan BT,Peirce SM,Botchwey EA

    更新日期:2017-03-27 00:00:00

  • Exploration of the role of the virulence factor ElrA during Enterococcus faecalis cell infection.

    abstract::Enterococcus faecalis, an organism generally not pathogenic for healthy humans, has the potential to cause disease in susceptible hosts. While it seems to be equipped to interact with and circumvent host immune defense, most of the molecular and cellular mechanisms underlying the enterococcal infectious process remain...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20206-6

    authors: Nunez N,Derré-Bobillot A,Gaubert S,Herry JM,Deschamps J,Wei Y,Baranek T,Si-Tahar M,Briandet R,Serror P,Archambaud C

    更新日期:2018-01-29 00:00:00

  • A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: A prospective, randomized and multi-center study.

    abstract::Several single-center studies have investigated whether narrow-band imaging (NBI) cystoscopy is more effective in detecting primary and recurrent non-muscle invasive bladder cancer (NMIBC) compared with white-light imaging (WLI) cystoscopy. In this study, we further evaluated the diagnostic value of NBI cystoscopy com...

    journal_title:Scientific reports

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1038/srep10905

    authors: Ye Z,Hu J,Song X,Li F,Zhao X,Chen S,Wang X,He D,Fan J,Ye D,Xing J,Pan T,Wang D

    更新日期:2015-06-05 00:00:00

  • Young onset type 2 diabetic patients might be more sensitive to metformin compared to late onset type 2 diabetic patients.

    abstract::It is unknown whether YOD (young onset diabetes) and LOD (late onset diabetes) require similar insulin doses for intensive insulin therapy with a metformin add-on to achieve glycemic control. We analyzed data from our two previously performed randomized, controlled open-label trials. Patients were randomized to receiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16658-x

    authors: Li FF,Liu BL,Yin GP,Zhang DF,Zhai XF,Chen MY,Su XF,Wu JD,Ye L,Ma JH

    更新日期:2017-11-27 00:00:00

  • The adaptive value of camouflage and colour change in a polymorphic prawn.

    abstract::Camouflage has been a textbook example of natural selection and adaptation since the time of the earliest evolutionists. However, aside from correlational evidence and studies using artificial dummy prey, experiments directly showing that better camouflaged prey to predator vision are at reduced risk of attack are lac...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34470-z

    authors: Duarte RC,Stevens M,Flores AAV

    更新日期:2018-10-30 00:00:00

  • Rapid colorimetric loop-mediated isothermal amplification for hypersensitive point-of-care Staphylococcus aureus enterotoxin A gene detection in milk and pork products.

    abstract::Staphylococcus aureus strains carrying enterotoxin A gene (sea) causes food poisoning and cannot be distinguished from non-pathogenic strains by the culture method. Here, we developed a rapid, specific and sensitive visual detection of sea using loop-mediated isothermal amplification (LAMP) combined with nanogold prob...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-64710-0

    authors: Srimongkol G,Ditmangklo B,Choopara I,Thaniyavarn J,Dean D,Kokpol S,Vilaivan T,Somboonna N

    更新日期:2020-05-08 00:00:00

  • A new nanoscale metastable iron phase in carbon steels.

    abstract::Metastable ω phase is common in body-centred cubic (bcc) metals and alloys, including high-alloying steels. Recent theoretical calculations also suggest that the ω structure may act as an intermediate phase for face-centred cubic (fcc)-to-bcc transformation. Thus far, the role of the ω phase played in fcc-bcc martensi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep15331

    authors: Liu T,Zhang D,Liu Q,Zheng Y,Su Y,Zhao X,Yin J,Song M,Ping D

    更新日期:2015-10-27 00:00:00

  • Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.

    abstract::Although recovery following a stroke is limited, undamaged neurons under the right conditions can establish new connections and take on-board lost functions. Sonic hedgehog (Shh) signaling is integral for developmental axon growth, but its role after injury has not been fully examined. To investigate the effects of Sh...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep21896

    authors: Berretta A,Gowing EK,Jasoni CL,Clarkson AN

    更新日期:2016-02-23 00:00:00

  • EV-3, an endogenous human erythropoietin isoform with distinct functional relevance.

    abstract::Generation of multiple mRNAs by alternative splicing is well known in the group of cytokines and has recently been reported for the human erythropoietin (EPO) gene. Here, we focus on the alternatively spliced EPO transcript characterized by deletion of exon 3 (hEPOΔ3). We show co-regulation of EPO and hEPOΔ3 in human ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03167-0

    authors: Bonnas C,Wüstefeld L,Winkler D,Kronstein-Wiedemann R,Dere E,Specht K,Boxberg M,Tonn T,Ehrenreich H,Stadler H,Sillaber I

    更新日期:2017-06-16 00:00:00

  • Reference genes for quantitative real-time PCR analysis in symbiont Entomomyces delphacidicola of Nilaparvata lugens (Stål).

    abstract::Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is a major rice pest that harbors an endosymbiont ascomycete fungus, Entomomyces delphacidicola str. NLU (also known as yeast-like symbiont, YLS). Driving by demand of novel population management tactics (e.g. RNAi), the importance of YLS has been studied and revealed...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42206

    authors: Wan PJ,Tang YH,Yuan SY,He JC,Wang WX,Lai FX,Fu Q

    更新日期:2017-02-13 00:00:00

  • Effect of adipose-derived mesenchymal stem cell transplantation on vascular calcification in rats with adenine-induced kidney disease.

    abstract::Previous studies have investigated the use of mesenchymal stem cells (MSCs) to treat damaged kidneys. However, the effect of adipose-derived MSCs (ASCs) on vascular calcification in chronic kidney disease (CKD) is still poorly understood. In the present study, we explored the potential of ASCs for the treatment of CKD...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14492-9

    authors: Yokote S,Katsuoka Y,Yamada A,Ohkido I,Yokoo T

    更新日期:2017-10-25 00:00:00

  • Highly Effective Conductance Modulation in Planar Silicene Field Effect Devices Due to Buckling.

    abstract::Silicene is an exciting two-dimensional material that shares many of graphene's electronic properties, but differs in its structural buckling. This buckling allows opening a bandgap in silicene through the application of a perpendicular electric field. Here we show that this buckling also enables highly effective modu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep14815

    authors: Al-Dirini F,Hossain FM,Mohammed MA,Nirmalathas A,Skafidas E

    更新日期:2015-10-06 00:00:00

  • Network diffusion-based analysis of high-throughput data for the detection of differentially enriched modules.

    abstract::A relation exists between network proximity of molecular entities in interaction networks, functional similarity and association with diseases. The identification of network regions associated with biological functions and pathologies is a major goal in systems biology. We describe a network diffusion-based pipeline f...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34841

    authors: Bersanelli M,Mosca E,Remondini D,Castellani G,Milanesi L

    更新日期:2016-10-12 00:00:00

  • Identification of conserved proteins from diverse shell matrix proteome in Crassostrea gigas: characterization of genetic bases regulating shell formation.

    abstract::The calcifying shell is an excellent model for studying biomineralization and evolution. However, the molecular mechanisms of shell formation are only beginning to be elucidated in Mollusca. It is known that shell matrix proteins (SMPs) play important roles in shell formation. With increasing data of shell matrix prot...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45754

    authors: Feng D,Li Q,Yu H,Kong L,Du S

    更新日期:2017-04-04 00:00:00