n and p type character of single molecule diodes.

abstract：:Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could also contribute to u...

journal_title：Scientific reports

authors： Sato TK,Kawano S,Endo T

更新日期：2019-05-21 00:00:00

abstract：:Routine antimicrobial susceptibility testing (AST) can prevent deaths due to bacteria and reduce the spread of multi-drug-resistance, but cannot be regularly performed in resource-limited-settings due to technological challenges, high-costs, and lack of trained professionals. We demonstrate an automated and cost-effec...

journal_title：Scientific reports

authors： Feng S,Tseng D,Di Carlo D,Garner OB,Ozcan A

更新日期：2016-12-15 00:00:00

abstract：:Current approaches to predicting a cardiovascular disease (CVD) event rely on conventional risk factors and cross-sectional data. In this study, we applied machine learning and deep learning models to 10-year CVD event prediction by using longitudinal electronic health record (EHR) and genetic data. Our study cohort i...

journal_title：Scientific reports

authors： Zhao J,Feng Q,Wu P,Lupu RA,Wilke RA,Wells QS,Denny JC,Wei WQ

更新日期：2019-01-24 00:00:00

abstract：:NLRP3 inflammasomes recognize non-microbial danger signals and induce release of proinflammatory cytokine interleukin (IL)-1β, leading to sterile inflammation in cardiovascular disease. Because sterile inflammation is involved in doxorubicin (Dox)-induced cardiotoxicity, we investigated the role of NLRP3 inflammasomes...

journal_title：Scientific reports

authors： Kobayashi M,Usui F,Karasawa T,Kawashima A,Kimura H,Mizushina Y,Shirasuna K,Mizukami H,Kasahara T,Hasebe N,Takahashi M

更新日期：2016-05-26 00:00:00

abstract：:Although attempts have been made to reveal the relationships between bacteria and human health, little is known about the species and function of the microbial community associated with oral diseases. In this study, we report the sequencing of 16 metagenomic samples collected from dental swabs and plaques representing...

journal_title：Scientific reports

authors： Wang J,Qi J,Zhao H,He S,Zhang Y,Wei S,Zhao F

更新日期：2013-01-01 00:00:00

abstract：:The identification of the earliest dogs is challenging because of the absence and/or mosaic pattern of morphological diagnostic features in the initial phases of the domestication process. Furthermore, the natural occurrence of some of these characters in Late Pleistocene wolf populations and the time it took from the...

journal_title：Scientific reports

authors： Boschin F,Bernardini F,Pilli E,Vai S,Zanolli C,Tagliacozzo A,Fico R,Fedi M,Corny J,Dreossi D,Lari M,Modi A,Vergata C,Tuniz C,Moroni A,Boscato P,Caramelli D,Ronchitelli A

更新日期：2020-08-07 00:00:00

abstract：:Graphite's capacity of intercalating lithium in rechargeable batteries is limited (theoretically, 372 mAh g-1) due to low diffusion within commensurately-stacked graphene layers. Graphene foam with highly enriched incommensurately-stacked layers was grown and applied as an active electrode in rechargeable batteries. A...

journal_title：Scientific reports

authors： Paronyan TM,Thapa AK,Sherehiy A,Jasinski JB,Jangam JS

更新日期：2017-01-06 00:00:00

abstract：:Polarization of macrophages is regulated through complex signaling networks. Correlating miRNA and mRNA expression over time after macrophage polarization has not yet been investigated. We used paired RNA-Seq and miRNA-Seq experiments to measure the mRNA and miRNA expression in bone marrow-derived macrophages over a t...

journal_title：Scientific reports

authors： Lu L,McCurdy S,Huang S,Zhu X,Peplowska K,Tiirikainen M,Boisvert WA,Garmire LX

更新日期：2016-12-16 00:00:00

abstract：:While previous studies separately demonstrate EEG spectral modulations during speech preparation and ERP responses to the listened speech, it is unclear whether these responses are related on a trial-by-trial basis between a speaker and listener. In order to determine whether these responses are related in real-time, ...

journal_title：Scientific reports

authors： Bridwell DA,Henderson S,Sorge M,Plis S,Calhoun VD

更新日期：2018-08-27 00:00:00

abstract：:The dynamic structure of proteins is essential for their functions and may include large conformational transitions which can be studied by molecular dynamics (MD) simulations. However, details of these transitions are difficult to automatically track. To facilitate their analysis, we developed two scores of correlati...

journal_title：Scientific reports

authors： Taddese B,Garnier A,Abdi H,Henrion D,Chabbert M

更新日期：2020-09-28 00:00:00

abstract：:A novel III-Nitride digital alloy (DA) with ultra-broadband optical gain is proposed. Numerical analysis shows a 50-period InN/GaN DA yields minibands that are densely quantized by numerous confined states. Interband transitions between the conduction and valence minibands create ultra-broadband optical gain spectra w...

journal_title：Scientific reports

authors： Sun W,Tan CK,Wierer JJ Jr,Tansu N

更新日期：2018-02-15 00:00:00

abstract：:HIF-1α, an essential transcription factor under hypoxic condition, is indispensable for chondrocytes during skeletal development but its expression and roles in articular chondrocytes are yet to be revealed. We examined HIF-1α protein expression and the hypoxic condition during mouse osteoarthritis (OA) development us...

journal_title：Scientific reports

authors： Okada K,Mori D,Makii Y,Nakamoto H,Murahashi Y,Yano F,Chang SH,Taniguchi Y,Kobayashi H,Semba H,Takeda N,Piao W,Hanaoka K,Nagano T,Tanaka S,Saito T

更新日期：2020-03-25 00:00:00

abstract：:Studies focusing on biofilm assembly in deep-sea environments are rarely conducted. To examine the effects of substrate type on microbial community assembly, biofilms were developed on different substrates for different durations at two locations in the Red Sea: in a brine pool and in nearby bottom water (NBW) adjacen...

journal_title：Scientific reports

authors： Zhang WP,Wang Y,Tian RM,Bougouffa S,Yang B,Cao HL,Zhang G,Wong YH,Xu W,Batang Z,Al-Suwailem A,Zhang XX,Qian PY

更新日期：2014-10-17 00:00:00

abstract：:Soil water retention curve (SWRC) plays an important role in simulating soil water movement and assessing soil water holding capacity and availability. Comparison of fitness between different models to determine the best SWRC model of specific regions is required. In this study, three popular models, van Genuchten, Br...

journal_title：Scientific reports

authors： Pan T,Hou S,Liu Y,Tan Q

更新日期：2019-12-05 00:00:00

abstract：:Breast cancer is a heterogeneous disease with differences in its clinical, molecular and biological features. Traditionally, immunohistochemical markers together with clinicopathologic parameters are used to classify breast cancer and to predict disease outcome. Triple-negative breast cancer (TNBC) is a particular typ...

journal_title：Scientific reports

authors： Manica GC,Ribeiro CF,Oliveira MA,Pereira IT,Chequin A,Ramos EA,Klassen LM,Sebastião AP,Alvarenga LM,Zanata SM,Noronha L,Rabinovich I,Costa FF,Souza EM,Klassen G

更新日期：2017-03-15 00:00:00

abstract：:Previous studies have demonstrated that gestational diabetes mellitus (GDM) and Type 2 diabetes mellitus (T2D) share common genetic polymorphisms. We conducted meta-analysis and subgroup analysis of all available variants and determined the effects of confounding and experimental components on the genetic association ...

journal_title：Scientific reports

authors： Wu L,Cui L,Tam WH,Ma RC,Wang CC

更新日期：2016-07-29 00:00:00

abstract：:Exotic pattern formation as a result of drying of an aqueous solution containing DNA and silica nanoparticles is reported. The pattern due to segregation was found to critically depend on the relative ratio of nanoparticles and DNA, as revealed by polarization microscopy, scanning electron microscopy, and fluorescence...

journal_title：Scientific reports

authors： Joksimovic R,Watanabe S,Riemer S,Gradzielski M,Yoshikawa K

更新日期：2014-01-13 00:00:00

abstract：:We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...

journal_title：Scientific reports

authors： Liu J,Au Yeung SL,Lin SL,Leung GM,Schooling CM

更新日期：2016-12-20 00:00:00

abstract：:The functions of female song found in a few cicadas have rarely been studied. In the cicada Subpsaltria yangi we investigated the acoustic behaviour and signal structure of songs produced by females, the phonotaxis of males, and mate choice, as well as the selective pressure imposed on this species by predators. Pair-...

journal_title：Scientific reports

authors： Hou Z,Luo C,Roberts JD,Wei C

更新日期：2017-07-25 00:00:00

abstract：:Determining accurate absolute surface energies for polar surfaces of semiconductors has been a great challenge in decades. Here, we propose pseudo-hydrogen passivation to calculate them, using density functional theory approaches. By calculating the energy contribution from pseudo-hydrogen using either a pseudo molecu...

journal_title：Scientific reports

authors： Zhang Y,Zhang J,Tse K,Wong L,Chan C,Deng B,Zhu J

更新日期：2016-02-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Yu C,Li T,Zhang R,Yang X,Yang Z,Xin L,Zhao Z

更新日期：2020-04-29 00:00:00

abstract：:The fusion of villous cytotrophoblasts into the multinucleated syncytiotrophoblast is critical for the essential functions of the mammalian placenta. Using RNA-Seq gene expression and quantitative protein expression, we identified genes and their cognate proteins which are coordinately up- or down-regulated in two cel...

journal_title：Scientific reports

authors： Azar C,Valentine M,Trausch-Azar J,Druley T,Nelson DM,Schwartz AL

更新日期：2018-03-23 00:00:00

abstract：:Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in vitro fertilization...

journal_title：Scientific reports

authors： Honda A,Tachibana R,Hamada K,Morita K,Mizuno N,Morita K,Asano M

更新日期：2019-08-09 00:00:00

abstract：:Tobacco smoking is the major cause of many chronic diseases, especially lung cancer. Knowledge about population-wide tobacco use and exposure is essential to characterise its burden on public health and evaluate policy efficacy. Obtaining such knowledge remains challenging with current methods (e.g., surveys, biomonit...

journal_title：Scientific reports

authors： Lai FY,Lympousi K,Been F,Benaglia L,Udrisard R,Delémont O,Esseiva P,Thomaidis NS,Covaci A,van Nuijs ALN

更新日期：2018-09-05 00:00:00

abstract：:Due to the increasing environmental impact of food production, carbon footprint as an indicator can guide farmland management. This study established a method and estimated the carbon footprint of grain production in China based on life cycle analysis (LCA). The results showed that grain production has a high carbon f...

journal_title：Scientific reports

authors： Zhang D,Shen J,Zhang F,Li Y,Zhang W

更新日期：2017-06-29 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a hyperglycaemic imbalance first recognized during pregnancy, and affects up to 22% of pregnancies worldwide, bringing negative maternal-fetal consequences in the short- and long-term. In order to better characterize GDM in pregnant women, 100 blood plasma samples (50 GDM and 50 ...

journal_title：Scientific reports

authors： Bernardes-Oliveira E,de Freitas DLD,de Morais CLM,Cornetta MDCM,Camargo JDAS,de Lima KMG,Crispim JCO

更新日期：2020-11-06 00:00:00

abstract：:Next generation sequencing has disrupted genetic testing, allowing far more scope in the tests applied. The appropriate sections of the genome to be tested can now be readily selected, from single mutations to whole-genome sequencing. One product offering within this spectrum are focused exomes, targeting ~5,000 genes...

journal_title：Scientific reports

authors： Pengelly RJ,Ward D,Hunt D,Mattocks C,Ennis S

更新日期：2020-02-24 00:00:00

abstract：:The decomposition of methane (CH4) is a catalytically important reaction in the production of syngas that is used to make a wide spectrum of hydrocarbons and alcohols, and a principal carbon deposition pathway in methane reforming. Literatures suggest that stepped Ni surface is uniquely selective toward methane decomp...

journal_title：Scientific reports

authors： Arevalo RL,Aspera SM,Escaño MCS,Nakanishi H,Kasai H

更新日期：2017-10-25 00:00:00

abstract：:Parasite death via ion channel activations is the hallmark of anthelmintic and antiparasitic drugs. Glutamate gated chloride channel (GluCl) is a prominent targets for drug selection and design in parasitology. We report several iodine-fluorine based lead activators of GluCl by computational studies and structure-acti...

journal_title：Scientific reports

authors： Rajasekharan SK,Lee JH,Ravichandran V,Kim JC,Park JG,Lee J

更新日期：2019-02-14 00:00:00

abstract：:Pulse wave transit time (PWTT) has been widely used as an index in assessing arterial stiffness. Percutaneous coronary intervention (PCI) is usually applied to the treatment of coronary artery disease (CAD). Research on the changes in PWTT caused by PCI is helpful for understanding the impact of the PCI procedure. In ...

journal_title：Scientific reports

authors： Ji L,Liu C,Li P,Wang X,Liu C,Hou Y

更新日期：2018-01-08 00:00:00