Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Rombaut D,Chiu HS,Decaesteker B,Everaert C,Yigit N,Peltier A,Janoueix-Lerosey I,Bartenhagen C,Fischer M,Roberts S,D'Haene N,De Preter K,Speleman F,Denecker G,Sumazin P,Vandesompele J,Lefever S,Mestdagh Pdoi
10.1038/s41598-019-46785-6subject
Has Abstractpub_date
2019-07-17 00:00:00pages
10536issue
1issn
2045-2322pii
10.1038/s41598-019-46785-6journal_volume
9pub_type
已发布勘误abstract::Malaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clusters of malaria incidence in Loreto region 2002-2013 and to determine signi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40350
更新日期:2017-01-16 00:00:00
abstract::We investigate collective modes in three dimensional (3D) gapless multi-Weyl semimetals with anisotropic energy band dispersions (i.e., with a positive integer J). For comparison, we also consider the gapless semimetals with the isotropic band dispersions (i.e. E ~ kJ). We calculate analytically long-wavelength plasma...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34023
更新日期:2016-09-30 00:00:00
abstract::During interpersonal interactions, people perform actions with different forms of vitality, communicating their positive or negative attitude toward others. For example, a handshake can be "soft" or "vigorous", a caress can be 'kind' or 'rushed'. While previous studies have shown that the dorso-central insula is a key...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73728-3
更新日期:2020-10-09 00:00:00
abstract::Lipid mediators play pivotal roles in colorectal cancer and colitis, but only a limited member of the phospholipase A2 (PLA2) subtypes, which lie upstream of various lipid mediators, have been implicated in the positive or negative regulation of these diseases. Clinical and biochemical evidence suggests that secreted ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12434-z
更新日期:2017-09-25 00:00:00
abstract::High operating temperatures can have very deleterious effects on the long-term performance of high-Cr, creep-resistant steels used, for example, in the structural components of power plants. For the popular creep-resistant steel X20CrMoV12.1 we analysed the processes of carbide growth using a variety of analytical tec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29734
更新日期:2016-07-13 00:00:00
abstract::Nucleosome not only directly affects cellular processes, such as DNA replication, recombination, and transcription, but also severs as a fundamentally important target of epigenetic modifications. Our previous study indicated that the bending property of DNA is important in nucleosome formation, particularly in predic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27247-x
更新日期:2018-06-11 00:00:00
abstract::Cohesins are vital for chromosome organisation during meiosis and mitosis. In addition to the important function in sister chromatid cohesion, these complexes play key roles in meiotic recombination, DSB repair, homologous chromosome pairing and segregation. Egg-laying mammals (monotremes) feature an unusually complex...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04560-5
更新日期:2017-06-26 00:00:00
abstract::Visceral adiposity index (VAI) has been associated with various cardio-metabolic diseases; however, there is limited information about its association with cerebrovascular diseases. In this study, we evaluated the relationship between VAI and silent brain infarct (SBI). We evaluated a consecutive series of healthy vol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74454-6
更新日期:2020-10-14 00:00:00
abstract::The association between alcohol consumption and kidney function is intriguing, but study results are mixed and controversial. We examined the association of alcohol consumption with the overall change in kidney function over 12 years. We analyzed data from a population-based cohort that was part of the Korean Genome a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81777-5
更新日期:2021-01-27 00:00:00
abstract::The iron binding capacities (IBC) of fulvic acid (FA) and humic acid (HA) were determined in the salinity range from 5 to 40. The results indicated that IBC decreased while salinity increased. In addition, dissolved iron (dFe), FA and HA were also determined along the Yangtze River estuary's increasing salinity gradie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01533-6
更新日期:2017-05-03 00:00:00
abstract::DDX3, a subunit of CK1ε, phosphorylates Dvl2 to promote β-catenin activation. Overexpression of the Dvl2 protein results in potent activation of β-catenin/TCF signaling in colorectal cancer. Therefore, we hypothesized that DDX3 might promote tumor invasion via the CK1ε/Dvl2 axis due to β-catenin/TCF activation. Wester...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21483
更新日期:2016-02-19 00:00:00
abstract::Release of pro-inflammatory mediators by mast cells is a key feature of allergic disease. The 'dogma' is that IgE molecules merely sensitise mast cells by binding FcεRI prior to cross-linking by multivalent allergen, receptor aggregation and mast cell activation. However, certain monoclonal IgE antibodies have been sh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09538
更新日期:2015-04-20 00:00:00
abstract::Wound healing is regulated by complex interactions between the keratinocytes and other cell types including fibroblasts. Recently, adipose-derived mesenchymal stromal/stem cells (ASCs) have been reported to influence wound healing positively via paracrine involvement. However, their roles in keratinocytes are still ob...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54797-5
更新日期:2019-12-04 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-23089-9
更新日期:2018-03-14 00:00:00
abstract::Single nucleotide polymorphisms (SNPs) in commercial arrays have often been discovered in a small number of samples from selected populations. This ascertainment skews patterns of nucleotide diversity and affects population genetic inferences. We propose a demographic inference pipeline that explicitly models the SNP ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28539-y
更新日期:2018-07-05 00:00:00
abstract::NETs constitute a network of DNA and proteins released by neutrophils in response to infectious and immunologic triggers. NET proteins are recognized as autoantigens in ANCA vasculitis; limited knowledge is available in other autoimmune pathologies. The composition of NETs produced ex vivo by resting and Phorbol-myris...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-019-44379-w
更新日期:2019-05-28 00:00:00
abstract::Short-term prospective studies have suggested that pulmonary tuberculosis (TB) preludes permanent loss of lean tissue and fat mass even when TB treatment is effective. The aim of this study was to estimate the risk of sarcopenia and osteoporosis among Korean male TB survivors. Data of the population-based, Korea Natio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12419-y
更新日期:2017-10-13 00:00:00
abstract::Semen fertilizing potential is dependent upon the morphological, functional and molecular attributes of sperm. Sperm microRNAs (miRNAs) were recently shown to hold promise regarding their association with different fertility phenotypes. However, their role in fertility regulation remains to be determined. We postulate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46775-8
更新日期:2019-07-17 00:00:00
abstract::Zika virus (ZIKV) causes significant public health concerns because of its association with congenital malformations, neurological disorders in adults, and, more recently, death. Considering the necessity to mitigate ZIKV-associated diseases, antiviral interventions are an urgent necessity. Sofosbuvir, a drug in clini...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09797-8
更新日期:2017-08-25 00:00:00
abstract::A new approach to estimate the Shannon entropy of a long-range correlated sequence is proposed. The entropy is written as the sum of two terms corresponding respectively to power-law (ordered) and exponentially (disordered) distributed blocks (clusters). The approach is illustrated on the 24 human chromosome sequences...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02721
更新日期:2013-01-01 00:00:00
abstract::Epilepsy is a chronic neurological disease with a variable therapeutic response. To design effective treatment strategies for epilepsy, it is important to understand treatment responses and predictive factors. However, limited data are available in Africa, including Ethiopia. The aim of this study was therefore to ass...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52574-y
更新日期:2019-11-07 00:00:00
abstract::Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks of incursion into FMD-free co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32693-8
更新日期:2018-10-02 00:00:00
abstract::Kmmig1 as a disrupted mutant of MIG1 encoding a regulator for glucose repression in Kluyveromyces marxianus exhibits a histidine-auxotrophic phenotype. Genome-wide expression analysis revealed that only HIS4 in seven HIS genes for histidine biosynthesis was down-regulated in Kmmig1. Consistently, introduction of HIS4 ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46411-5
更新日期:2019-07-09 00:00:00
abstract::Oxidative stress (OS), mitochondrial dysfunction, and dysregulation of alpha-synuclein (aSyn) homeostasis are key pathogenic factors in Parkinson's disease. Nevertheless, the role of aSyn in mitochondrial physiology remains elusive. Thus, we addressed the impact of aSyn specifically on mitochondrial response to OS in ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42942
更新日期:2017-02-22 00:00:00
abstract::In southeastern China (SEC), the precipitation amount produced by the East Asian summer monsoon (EASM) is almost equivalent to that during the non-summer monsoon (NSM) period, both of them significantly affecting agriculture and socioeconomy. Here, we present a seasonally-resolved stalagmite δ18O record (δ18Os) for th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30112-6
更新日期:2018-08-17 00:00:00
abstract::Migration and interactions of immune cells are routinely studied by time-lapse microscopy of in vitro migration and confrontation assays. To objectively quantify the dynamic behavior of cells, software tools for automated cell tracking can be applied. However, many existing tracking algorithms recognize only rather sh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39725-x
更新日期:2019-03-01 00:00:00
abstract::Multiple sclerosis (MS) is a neurodegenerative autoimmune disease, where chronic inflammation plays an essential role in its pathology. A feature of MS is the production of autoantibodies stimulated by an altered-peptide-ligand response and epitope spreading, resulting in loss of tolerance for self-proteins. The invol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25391-y
更新日期:2018-05-04 00:00:00
abstract::The eruptive activity of basaltic hotspot volcanoes displays major fluctuations on times scales of years to decades. Theses fluctuations are thought to reflect changes in the rate of mantle melt supply. However, the crustal filter generally masks the mantle processes involved. Here, we show that the cyclic and general...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32809-0
更新日期:2018-09-27 00:00:00
abstract::In mosquitoes, precise and efficient finding of a host animal is crucial for survival. One of the poorly understood aspects of mosquito blood-feeding behavior is how these insects target an optimal site in order to penetrate the skin and blood vessels without alerting the host animal. Here we provide new findings that...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13444
更新日期:2015-08-26 00:00:00
abstract::One-year time series of current velocities and hydrographic parameters based on four deep moorings deployed east of the Luzon Strait are employed to study the deep current at the western boundary (DCWB) of the northern Philippine Basin. While the mean current is relatively weak, the DCWB is highly variable on an intra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32541-9
更新日期:2018-09-25 00:00:00