Impact of morphine on the expression of insulin receptor and protein levels of insulin/IGFs in rat neural stem cells.

abstract：:In order to assess functional skills of older adults, both timed up and go (TUG) test and gait speed (GS) test are well validated concerning their predictive capacities. However, the question remains unclear which one of these tests represents better the whole physical performance of older adults. The aim of this stud...

journal_title：Neuroscience letters

authors： Kubicki A

更新日期：2014-08-08 00:00:00

abstract：:N-Methyl-D-aspartate (NMDA) receptors were expressed in Xenopus oocytes from injected mRNA. The presence of an alternatively-spliced insertion encoding 21 amino acids at the N-terminus of the NMDAR1 (NR1(111)) subunit, made homomeric assemblies of the receptor more sensitive to ketamine and MK-801 than receptors assem...

journal_title：Neuroscience letters

authors： Rodríguez-Paz JM,Anantharam V,Treistman SN

更新日期：1995-05-12 00:00:00

abstract：:New psychoactive substances (NPSs), i.e., newly designed substances with chemical residues that are slightly different from those of known psychoactive substances, have been emerging since the late 2000s, and social problems related to the use of these substances are increasing globally. Two such NPSs are 4-chloro-2,5...

journal_title：Neuroscience letters

authors： Cha HJ,Jeon SY,Jang HJ,Shin J,Kim YH,Suh SK

更新日期：2018-05-29 00:00:00

abstract：:Dopamine metabolism and release were determined in the striata of rats sustaining varying damage to the nigrostriatal dopamine (DA) projection. DA metabolism, inferred from concentrations of dihydroxy-phenylacetic acid (DOPAC) or homovanillic acid (HVA), decreased with DA denervation of more than 20%. Dopamine release...

journal_title：Neuroscience letters

authors： Altar CA,Marien MR

更新日期：1989-01-30 00:00:00

abstract：:CSF-A beta 42 may be a marker of Alzheimer's disease (AD). A decreased level of CSF-A beta 42 is consistently found in AD and has been suggested to be related to the deposition of amyloid plaques in the brain. However, low CSF-A beta 42 levels have also been found in disorders devoid of plaques, for instance Creutzfel...

journal_title：Neuroscience letters

authors： Sjögren M,Gisslén M,Vanmechelen E,Blennow K

更新日期：2001-11-13 00:00:00

abstract：:The epithelial membrane protein 1 (EMP1) plays a role in neuronal differentiation and neurite outgrowth, which are involved in the pathogenesis of major depressive disorder (MDD). We sought to determine whether the EMP1 gene is implicated in MDD. We determined the mRNA expression levels of the EMP1 gene in peripheral-...

journal_title：Neuroscience letters

authors： Nakataki M,Iga J,Numata S,Yoshimoto E,Kodera K,Watanabe SY,Song H,Ueno S,Ohmori T

更新日期：2011-02-04 00:00:00

abstract：:We have investigated the effect of ethanol upon vasopressin (AVP) content in brain and upon in-vitro release of AVP from the rat median eminence. In-vitro ethanol concentrations (5-25 mM), comparable to behaviorally relevant blood ethanol levels, induce a substantial inhibition of AVP release from the median eminence,...

journal_title：Neuroscience letters

authors： Brinton RE,Gruener R,Deshmukh P,Yamamura HI

更新日期：1986-06-18 00:00:00

abstract：:MicroRNAs, such as miR-34, have been reported to influence age-related diseases. In this study, we explored the role of the miR-34a/Bcl-2 signaling pathway in age-related hearing loss (AHL). Using an AHL mouse model (C57BL/6), we found that the expression of miR-34a in the cochlea increased with age, whereas expressio...

journal_title：Neuroscience letters

authors： Huang Q,Zheng Y,Ou Y,Xiong H,Yang H,Zhang Z,Chen S,Ye Y

更新日期：2017-11-20 00:00:00

abstract：:Nor-binaltorphimine (nor-BNI) is kappa opioid receptor (KOR) antagonist with the extremely long duration in mice analgesic assay, in vivo. For the evaluation of long-lasting effect of nor-BNI, brain content and serum concentration of nor-BNI were quantified in comparison with those of naloxone (a short-acting non-spec...

journal_title：Neuroscience letters

authors： Kishioka S,Kiguchi N,Kobayashi Y,Yamamoto C,Saika F,Wakida N,Ko MC,Woods JH

更新日期：2013-09-27 00:00:00

abstract：:Interactions between emotional stress due to fear and hypovolemic stimuli on vasopressin secretion were studied in rats. Intraperitoneally injected dextran did not significantly change plasma osmolality and arterial blood pressure but increased blood hemoglobin and plasma vasopressin level. An i.v. infused physiologic...

journal_title：Neuroscience letters

authors： Onaka T,Yagi K

更新日期：1990-12-11 00:00:00

abstract：:The effects of gonadal steroids on serotonin (5-HT) synthesis and metabolism in the early developing brain were investigated. Seven-day-old (7 days post-hatch) tilapia, Oreochromis mossambicus were continuously treated with 17beta-estradiol (E2), methyltestosterone (MT) and para-chlorophenylalanine (p-PCA) up to the a...

journal_title：Neuroscience letters

authors： Tsai CL,Wang LH

更新日期：1999-04-02 00:00:00

abstract：:The repressor element-1 silencing transcription factor (REST) has emerged as a key controller of neuronal differentiation and has been shown to play a critical role in the expression of the neuronal phenotype; however, much has still to be learned about its role at specific developmental stages and about the functiona...

journal_title：Neuroscience letters

authors： Antoniotti S,Ruffinatti FA,Torriano S,Luganini A,D'Alessandro R,Lovisolo D

更新日期：2016-08-26 00:00:00

abstract：:Rats were treated with once-daily subcutaneous injections of atropine or normal saline for 10 days. Cryostat sections of fresh-frozen brain were subjected to quantitative muscarinic receptor ([3H]quinuclidinylbenzilate (QNB)) binding autoradiography, and quantitative in-situ hybridization autoradiography for beta-amyl...

journal_title：Neuroscience letters

authors： Beach TG,Walker DG,Cynader MS,Hughes LH

更新日期：1996-05-24 00:00:00

abstract：:Localizations of thalamic relay neurons of vibrissae, common fur of the muzzle and head, as well as those projecting to the cortical vibrissal field in mice with vibrissae coagulated at birth, have been studied by retrograde transport of peroxydase. The tracer was injected in the corresponding cortical areas. In coagu...

journal_title：Neuroscience letters

authors： Verney C,Farkas-Bargeton E,Verley R

更新日期：1982-10-23 00:00:00

abstract：:The number of active cells in each synchronous firing event in a set of 10 neurosecretory cells in the silkmoth Bombyx mori was estimated from the amplitude and waveform of compound action potentials. One to 10 cells discharged an action potential within a period of 30 ms and one to two or nine to 10 units became acti...

journal_title：Neuroscience letters

authors： Ichikawa T,Imafuku Y,Tawada K

更新日期：1999-04-02 00:00:00

abstract：:Here we examine hypothesis that short-term peripheral ZnSO(4)-induced anosmia can produce effects on c-fos expression within spinal cord and caudal medulla in male Wistar rats (n=4). Fos-like-immunoreactive cells revealed by avidin-biotin-peroxidase method show a significant bilateral increase in the nucleus proprius ...

journal_title：Neuroscience letters

authors： Kalueff AV,Maisky VA,Pilyavskii AI,Makarchuk NE

更新日期：2001-03-30 00:00:00

abstract：:The rat spinal cord slice preparation has been used to investigate the sensitivity of deep dorsal horn neurones to the excitatory amino acids N-methyl-D-aspartate (NMDA), quisqualate and L-glutamate. Intracellular recordings were made from 44 neurones in laminae III-VI of 14- to 16-day rats. Superfusion of quisqualate...

journal_title：Neuroscience letters

authors： King AE,Thompson SW,Urban L,Woolf CJ

更新日期：1988-07-08 00:00:00

abstract：:In brainstem slices of guinea pigs perfused with artificial cerebro-spinal fluid (ACSF), the discharge of all the spontaneously active neurons of the medial vestibular nucleus (MVN) is regular. It has been reported that prolonged exposure to a low Ca(2+) medium could induce these neurons to fire bursts of spikes. In t...

journal_title：Neuroscience letters

authors： Ris L,Godaux E

更新日期：2001-01-12 00:00:00

abstract：:A growing body of evidence has demonstrated a role for group II metabotropic glutamate receptors (mGluRs) in the reinforcing effects of cocaine. These receptors are important given their location in limbic-related areas, and their ability to control the release of glutamate and other neurotransmitters. They are also p...

journal_title：Neuroscience letters

authors： Beveridge TJ,Smith HR,Nader MA,Porrino LJ

更新日期：2011-05-27 00:00:00

abstract：:An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in va...

journal_title：Neuroscience letters

authors： Dong L,Qi N,Ge RM,Cao CL,Lan F,Shen L

更新日期：2010-11-05 00:00:00

abstract：:Following the i.c.v. administration of antivasopressin serum the alpha-MPT-induced disappearance of noradrenaline was decreased in the dorsal septal nucleus, parafascicular nucleus and the rostral part of the nucleus tractus solitarii, whereas that of dopamine was lowered in the caudate nucleus and in the A2 region of...

journal_title：Neuroscience letters

authors： Versteeg DH,De Kloet ER,Greidanus TV,De Wied D

更新日期：1979-01-01 00:00:00

abstract：:The recurrence of dopamine-immunoreactive (DAi) fibers and the effect of the adrenocorticotrophic hormone (ACTH)-(4-9) analog ORG 2766 on this process were investigated 1, 4, 12 and 24 weeks after a unilateral 6-hydroxydopamine (6-OHDA) lesion in the nucleus accumbens (NAc). DAi fibers were almost completely absent 1 ...

journal_title：Neuroscience letters

authors： Vos PE,Steinbusch HW,Van Ree JM

更新日期：1996-03-22 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a gene that shares a bi-directional promoter with the Parkinson's disease associated gene parkin. The functional role of PACRG is not well understood, although the gene has been associated with parkinsonian syndromes and more recently with eukaryotic cilia and flagella. We investiga...

journal_title：Neuroscience letters

authors： Wilson GR,Tan JT,Brody KM,Taylor JM,Delatycki MB,Lockhart PJ

更新日期：2009-08-21 00:00:00

abstract：:We studied the effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) on seizure susceptibility in rats. rTMS of 1000 pulses at 0.5 Hz led to a prolonged latency for seizure development after an intraperitoneal injection of pentylenetetrazol. The rTMS effectively prevented the development of stat...

journal_title：Neuroscience letters

authors： Akamatsu N,Fueta Y,Endo Y,Matsunaga K,Uozumi T,Tsuji S

更新日期：2001-09-14 00:00:00

abstract：:Repeated exposure to dizocilpine (MK-801) can be used as a model of schizophrenia that incorporates disease progression. Proton magnetic resonance spectroscopy (1H MRS) has been widely used to investigate schizophrenia-related alterations in glutamate (Glu). The purpose of this study was to investigate metabolic alter...

journal_title：Neuroscience letters

authors： Yoo CH,Song KH,Lim SI,Lee DW,Woo DC,Choe BY

更新日期：2017-01-10 00:00:00

abstract：:The hippocampal formation plays a critical role in episodic memory formation and spatial navigation. Within the hippocampus, the subiculum is considered to be a hub connecting the hippocampal formation to the remainder of the brain. There are functional differences between the dorsal and ventral part of subiculum, whi...

journal_title：Neuroscience letters

authors： Tang H,Wu GS,Xie J,He X,Deng K,Wang H,Xu F,Luo HR

更新日期：2016-08-26 00:00:00

abstract：:Previous studies have reported that intrahemispheric connections between area 17 (V1, striate cortex) and other cortical visual areas are not point-to-point, but instead have some degree of convergence and divergence. Many pathological conditions can interfere with the normal development of patterns of cortico-cortica...

journal_title：Neuroscience letters

authors： Bock AS,Olavarria JF

更新日期：2011-09-01 00:00:00

abstract：:We compared cerebrospinal fluid (CSF) and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 36 patients with multiple sclerosis (MS) and 32 matched controls. The mean CSF vitamin E levels and the CSF/serum vitamin E ratio did not differ significantly between the two study grou...

journal_title：Neuroscience letters

authors： Jiménez-Jiménez FJ,de Bustos F,Molina JA,de Andrés C,Gasalla T,Ortí-Pareja M,Zurdo M,Porta J,Castellano-Millán F,Arenas J,Enríquez de Salamanca R

更新日期：1998-06-12 00:00:00

abstract：:Serial sections of human brainstem were used to determine the total number of pigmented cells in locus coeruleus and, by immunohistochemical staining using an antiserum directed against human dopamine-beta-hydroxylase (DBH), the number of DBH-positive cells. In 12 brains from elderly control and dementia subjects ther...

journal_title：Neuroscience letters

authors： Iversen LL,Rossor MN,Reynolds GP,Hills R,Roth M,Mountjoy CQ,Foote SL,Morrison JH,Bloom FE

更新日期：1983-08-19 00:00:00

abstract：:A growing body of evidence suggests that Alzheimer's disease (AD) is associated with local inflammation processes, including the activation of inflammatory cytokines. We performed a case-control association study between sporadic AD patients and the exon 5 position +3953 polymorphism in the potent pro-inflammatory cyt...

journal_title：Neuroscience letters

authors： Rosenmann H,Meiner Z,Dresner-Pollak R,Kahana E,Aladjem Z,Grenader T,Wertman E,Abramsky O

更新日期：2004-06-10 00:00:00