Abstract:
:We compared cerebrospinal fluid (CSF) and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 36 patients with multiple sclerosis (MS) and 32 matched controls. The mean CSF vitamin E levels and the CSF/serum vitamin E ratio did not differ significantly between the two study groups. The serum levels of vitamin E and the serum vitamin E/cholesterol ratio were significantly lower in MS patients when compared with controls (P < 0.05 and P < 0.01, respectively). These values were not correlated with age, age at onset and duration of the disease in the patients group. These results suggest that CSF vitamin E concentrations are not a marker of activity of MS activity.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Jiménez-Jiménez FJ,de Bustos F,Molina JA,de Andrés C,Gasalla T,Ortí-Pareja M,Zurdo M,Porta J,Castellano-Millán F,Arenas J,Enríquez de Salamanca Rdoi
10.1016/s0304-3940(98)00370-xsubject
Has Abstractpub_date
1998-06-12 00:00:00pages
65-7issue
1eissn
0304-3940issn
1872-7972pii
S030439409800370Xjournal_volume
249pub_type
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