gamma-Aminobutyric acidB receptors in the rat brain: quantitative autoradiographic localization using [3H](-)-baclofen.

abstract：:The Nef protein of human immunodeficiency virus type 1 (HIV-1) is abundantly expressed in HIV-1-infected astrocytes and shares amino acid sequence homology to alpha-scorpion toxins which bind to potassium channels. Here we report effects of recombinant Nef and alpha-scorpion toxins on membrane potassium transport in h...

journal_title：Neuroscience letters

authors： Kort JJ,Jalonen TO

更新日期：1998-07-17 00:00:00

abstract：:Noise-induced hearing loss (NIHL) severely impacts the quality of life of affected individuals. Oxidative stress resulting from noise exposure is a significant cause of NIHL. Although histone deacetylase (HDAC) inhibitors were shown to protect against NIHL, the underlying mechanism remains unclear, and it is not known...

journal_title：Neuroscience letters

authors： Yang DH,Xie J,Liu K,Peng Z,Guo JY,Yu SK,Wang GP,Gong SS

更新日期：2017-11-01 00:00:00

abstract：:The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

journal_title：Neuroscience letters

authors： Wijers AA,Been PH,Romkes KS

更新日期：2005-02-10 00:00:00

abstract：:Previous studies have shown that the midbrain periaqueductal gray (PAG) projects to the ventrolateral medulla (VLM). Here, we studied PAG projections to the area of A1/C1 neurons in the VLM in the rat using phaseolus vulgaris leucoagglutinin (PHA-L) anterograde tracing combined with immunocytochemistry for tyrosine hy...

journal_title：Neuroscience letters

authors： Chen S,Aston-Jones G

更新日期：1995-08-04 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:We examined the rubrospinal projection to forelimb motoneurons (Mns) in cats, in comparison with the corticospinal projection. Under pentobarbital anesthesia, intracellular recordings were made from forelimb Mns following stimulation of the red nucleus (RN) and the cerebral peduncle (CP). Single pulse stimulation of t...

journal_title：Neuroscience letters

authors： Fujito Y,Imai T,Aoki M

更新日期：1991-06-10 00:00:00

abstract：:Transforming growth factor-β (TGF-β) is an anti-inflammatory cytokine and is expressed in the injured spinal cord. TGF-β signals through receptors to activate Smad proteins, which translocate into the nucleus. In the present study, we investigated the chronological alterations and cellular locations of the TGF-β/Smad ...

journal_title：Neuroscience letters

authors： Joko M,Osuka K,Usuda N,Atsuzawa K,Aoyama M,Takayasu M

更新日期：2013-08-09 00:00:00

abstract：:Neurite outgrowth is elicited from whole explants or dissociated neurons of 8--10-day-old chick embryo sensory, dorsal root ganglia when cultured in the presence of a high speed supernatant fraction (105,000 g) from homogenates of chick or rat heart, liver or brain. The neurite promoting activity is not identical to m...

journal_title：Neuroscience letters

authors： Lindsay RM,Tarbit J

更新日期：1979-05-01 00:00:00

abstract：:The trembler mouse suffers from a dominantly inherited mutation of the peripheral myelin protein 22 (PMP22) gene which results in an abnormal myelination of its peripheral nervous system. The recent identification of two different PMP22 mRNA differing in their 5' non-translated region led us to monitor their respectiv...

journal_title：Neuroscience letters

authors： Garbay B,Boiron-Sargueil F,Cassagne C

更新日期：1995-10-06 00:00:00

abstract：:Mirror neurons, which have now been found in the human and songbird as well as the macaque, respond to both the observation and the performance of the same action. It has been suggested that their matching response properties have evolved as an adaptation for action understanding; alternatively, these properties may a...

journal_title：Neuroscience letters

authors： Catmur C

更新日期：2013-04-12 00:00:00

abstract：:Tumor cells frequently express the insulin-like growth factor I (IGF-I). Recently we demonstrated that rat glioma cells when transfected with a vector encoding antisense IGF-I cDNA lost tumorigenicity and induced a tumor specific immune response involving CD8+ lymphocytes. Here we show that the cultured transfected ce...

journal_title：Neuroscience letters

authors： Trojan J,Duc HT,Upegui-Gonzalez LC,Hor F,Guo Y,Anthony D,Ilan J

更新日期：1996-07-05 00:00:00

abstract：:Recently, it has been hypothesized that the N-terminal portion of substance P (SP), SP(1-7), which results from the action of endopeptidase 24.11 (EC3.4.24.11), could be involved in mediating the depressor effects of baroreceptor afferent activation via its action on cells in the nucleus tractus solitarius (NTS). In t...

journal_title：Neuroscience letters

authors： Lasher RS,Lutz EM,Mulholland F,Sanderson R,Stewart JM,Bublitz C

更新日期：1990-09-04 00:00:00

abstract：:To clarify the possible role of in the in vivo toxic effects of 6-hydroxydopamine (6-OHDA), especially caspase activations, we examined its effects on striatal lipid peroxidation (LPO) and caspase activations in 6-OHDA-lesioned mice. Both dopamine (DA) levels and DA turnover were significantly changed by the 6-OHDA i....

journal_title：Neuroscience letters

authors： Tanaka K,Ogawa N,Asanuma M

更新日期：2006-12-20 00:00:00

abstract：:The interaction between ATP-activated channels and the nicotinic receptor-channels has been reported in neuronal cells. To elucidate the mechanisms underlying the interaction, the currents activated by ATP and acetylcholine (ACh) were recorded from cell-free membrane patches excised from rat sympathetic neurons. When ...

journal_title：Neuroscience letters

authors： Nakazawa K,Inoue K

更新日期：1993-11-26 00:00:00

abstract：:Diurnal variation of N-acetylserotonin in the retina was studied in male rats housed under a photoperiod of 12 h light and 12 h darkness (lights on at 06.00 h) for two weeks. N-acetylserotonin was extracted from the retina by ethyl acetate at pH less than or equal to 3 and was determined by radioimmunoassay. There is ...

journal_title：Neuroscience letters

authors： Pang SF,Yu HS,Tang PL

更新日期：1981-01-20 00:00:00

abstract：:Intracolonic (i.col.) administration of the PAR2-activating peptide (PAR2AP) SLIGRL-NH2 slowly develops visceral hypersensitivity to i.col. capsaicin in ddY mice. Thus, we further analyzed roles of PAR2 in colonic hypersensitivity, using the novel potent PAR2AP, 2-furoyl-LIGRL-NH2 and PAR2-knockout (KO) mice. In ddY m...

journal_title：Neuroscience letters

authors： Kawabata A,Kawao N,Kitano T,Matsunami M,Satoh R,Ishiki T,Masuko T,Kanke T,Saito N

更新日期：2006-07-10 00:00:00

abstract：:Changes in contingent negative variation (CNV), a brain-evoked potential related in arousal, as well as in serum triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), prolactin (PRL), cortisol and growth hormone (GH) levels were recorded in 12 male volunteers receiving either thyrotropin-releasing ...

journal_title：Neuroscience letters

authors： Strollo F,Amabile G,Fattapposta F,Strollo G,More M,Riondino G

更新日期：1988-11-11 00:00:00

abstract：:In vivo electrochemistry was used to determine the effects of locally applied raclopride (a D2 receptor antagonist) and SCH-23390 (a D1 receptor antagonist) on the clearance of locally applied dopamine in the striatum, nucleus accumbens, and medial prefrontal cortex of rats. Chronoamperometric recordings were continuo...

journal_title：Neuroscience letters

authors： Cass WA,Gerhardt GA

更新日期：1994-08-01 00:00:00

abstract：:The mechanisms responsible for the termination of paroxysmal depolarization shifts (PDS) were studied with intracellular recordings on CA1 neurons of rat hippocampal slices. Epileptiform activity was induced by application of penicillin, bicuculline or Mg-free artificial cerebrospinal fluid (ACSF). PDS in penicillin-c...

journal_title：Neuroscience letters

authors： Domann R,Westerhoff CH,Witte OW

更新日期：1994-07-18 00:00:00

abstract：:The phenotypic manifestation of McArdle disease varies considerably from one individual to the next. The purpose of this study was to assess the possible association between the clinical severity of the disease, and each of the genotypes PYGM (R50X), ACE (I/D), AMPD1 (Q12X), PPARGC1A (G482S) and ACTN3 (R577X). We also...

journal_title：Neuroscience letters

authors： Rubio JC,Gómez-Gallego F,Santiago C,García-Consuegra I,Pérez M,Barriopedro MI,Andreu AL,Martín MA,Arenas J,Lucia A

更新日期：2007-07-18 00:00:00

abstract：:Changes in the planning and control of discrete aiming movements in response to the introduction and removal of the Ebbinghaus size-contrast illusion were examined. Movements were executed faster to targets that appeared larger following movement initiation. The differences in movement time were associated with the po...

journal_title：Neuroscience letters

authors： Handlovsky I,Hansen S,Lee TD,Elliott D

更新日期：2004-08-19 00:00:00

abstract：:We compared cerebrospinal fluid (CSF) apolipoprotein (apo) A-I and apo E concentrations in early- and late-onset Alzheimer's disease (EOAD (n = 11), LOAD (n = 15), respectively) with those in control subjects (n = 23). CSF apo A-I levels in both EOAD and LOAD were consistent with control subjects. However, CSF apo E l...

journal_title：Neuroscience letters

authors： Song H,Saito K,Seishima M,Noma A,Urakami K,Nakashima K

更新日期：1997-08-15 00:00:00

abstract：:The vanilloid receptor-1 (TRPV1), expressed by nociceptive fibers, is a transducer of thermal and chemical nociceptive messages. However, endogenous ligands excite TRPV1 receptors localized on central nociceptive terminals and interneurons. Using immunocytochemistry at the ultrastructural level, we show that TRPV1 is ...

journal_title：Neuroscience letters

authors： Doly S,Fischer J,Salio C,Conrath M

更新日期：2004-03-04 00:00:00

abstract：:A right-brain damaged patient with pure tactile extinction was asked to report series of single or double light, brief touches delivered to both hands, the thumb or the pinkie of a single hand, the sides of a single index. The stimulated hand was positioned palm up or palm down, in front of or behind the patient, in a...

journal_title：Neuroscience letters

authors： Tinazzi M,Ferrari G,Zampini M,Aglioti SM

更新日期：2000-06-23 00:00:00

abstract：:Chronic social defeat stress in mice significantly decreases subsequent social interactions and induces other depression-like behaviors. Here we measured and manipulated levels of acetylated histone H3 (acH3), a chromatin mark of transcriptional activation, in the hippocampus and amygdala after ten continuous days of ...

journal_title：Neuroscience letters

authors： Covington HE 3rd,Vialou VF,LaPlant Q,Ohnishi YN,Nestler EJ

更新日期：2011-04-15 00:00:00

abstract：:The present study investigated one of the characteristics of No-go-related brain activity during somatosensory Go/No-go paradigms, by manipulating the stimulus site and response hand. Somatosensory event-related potentials (ERPs) were recorded in ten right-handed subjects. Electrical stimulation was delivered to the s...

journal_title：Neuroscience letters

authors： Nakata H,Sakamoto K,Kakigi R

更新日期：2010-07-12 00:00:00

abstract：:Acute and chronic damage to the central nervous system (CNS) releases large quantities of ATP. Whereas the ATP concentration in the extracellular space is normally in the micromolar range, under these conditions it increases to millimolar levels. A number of ligand-gated cationic channels termed P2X receptors (7 mamma...

journal_title：Neuroscience letters

authors： Franke H,Illes P

更新日期：2014-04-17 00:00:00

abstract：:Prolactin (PRL) has been shown to be altered by psychotropic drugs, including antidepressant drugs (ADs). Many studies have focused on the response to antidepressant treatment (especially related to the serotonergic system) using the fenfluramine test (PRF), however some data suggest lack of correlation between PRF an...

journal_title：Neuroscience letters

authors： Faron-Górecka A,Kuśmider M,Szafran-Pilch K,Kolasa M,Żurawek D,Gruca P,Papp M,Solich J,Pabian P,Dziedzicka-Wasylewska M

更新日期：2017-04-24 00:00:00

abstract：:Presenilin 1 mutations are the major cause of autosomal dominant Alzheimer's disease. Here we present evidence that pathogenic mutations in putative transmembrane domains 1, 2, 3, 4 and 6 align along helical faces, thus supporting the view that these are indeed transmembrane domains, and suggesting that disruption of ...

journal_title：Neuroscience letters

authors： Hardy J,Crook R

更新日期：2001-06-29 00:00:00

abstract：:An analysis was made of primary afferent and dorsal horn neuron responses to stimulation of genitalia of female cats. Three types of primary afferents responded to vaginal probing. The most common type responded maximally to the on- and off-ramps of non-noxious pressure applied directly to the clitoris. A second type ...

journal_title：Neuroscience letters

authors： Price DD,Bushnell MC,Iadarola MJ

更新日期：1981-10-01 00:00:00