A diurnal rhythm of N-acetylserotonin in the retina of rats.

abstract：:To investigate whether the xenon-induced inhibition of the transient receptor potential vanilloid type 1 (TRPV1) ion channel in rat dorsal root ganglion (DRG) neurons reduces nociceptive processing, we examined the effect of xenon in reducing the release of calcitonin gene-related peptide (CGRP) from those neurons. We...

journal_title：Neuroscience letters

authors： Calcott G,White JP,Nagy I

更新日期：2011-07-20 00:00:00

abstract：:Assessments of the pharmacological profiles of antipsychotic agents have shown that the serotonin receptor family is often involved in their pharmacodynamics. Response to antipsychotic therapy is highly variable, yet prognostic biomarkers are lacking. The aim of the study was to investigate the association of 14 singl...

journal_title：Neuroscience letters

authors： Zhou W,Chang W,Yan Y,Shen L,Li W,Yi Z,Qin S

更新日期：2018-09-14 00:00:00

abstract：:We studied anxiety-like behavior in the elevated plus-maze (EPM) tests in male Lewis rats on days 2 and 4 of adjuvant arthritis (AA). In plasma we analyzed C-reactive protein (CRP), albumin, ACTH, corticosterone, in the hippocampus the mRNA expression of interleukin-1β (IL-1β), interleukin-6 (IL-6), corticotrophin rel...

journal_title：Neuroscience letters

authors： Skurlova M,Stofkova A,Jurcovicova J

更新日期：2011-01-07 00:00:00

abstract：:Although the coadministration of lidocaine with propranolol interferes with the metabolic profile (pharmacokinetics), its pharmacodynamics is still unclear. In this report, we investigate whether propranolol can potentiate the effect of lidocaine. Rats received spinal anesthesia with lidocaine co-injected with propran...

journal_title：Neuroscience letters

authors： Chen YW,Chu CC,Chen YC,Hung CH,Li YT,Wang JJ

更新日期：2011-09-26 00:00:00

abstract：:Monosynaptic evoked responses were used to localize dorsal root ganglion (DRG) afferent terminals within organotypic fetal mouse spinal cord explants which had been chronically exposed to purified bovine gangliosides during early development. Ganglioside grown cultures showed a highly significant increase in dorsal co...

journal_title：Neuroscience letters

authors： Baker RE

更新日期：1983-10-31 00:00:00

abstract：:Treatment with acamprosate, a compound used for relapse prevention treatment of alcoholism, was recently shown to be associated with increased plasma concentration of beta-endorphin in rats selectively bred for high alcohol preference. The aim of our study was to prove this result in a comparative clinical study with ...

journal_title：Neuroscience letters

authors： Kiefer F,Jahn H,Otte C,Nakovics H,Wiedemann K

更新日期：2006-08-14 00:00:00

abstract：:Secondary optic projections were studied in the toad, Bufo marinus using the method of transneuronal transport of triated proline and fucose. Following a survival of 14 days after eye injection autoradiographic label was transported transneuronally to the contralateral nucleus isthmi, the deeper layers of the contrala...

journal_title：Neuroscience letters

authors： Mayner L

更新日期：1980-03-01 00:00:00

abstract：:It is well-known that cocaine dependence is a public health issue, and several studies stress the need to look for new and more effective treatments. Although the mesolimbic dopamine (DA) system, which originates in the ventral tegmental area (VTA) and projects to several forebrain structures, is known to be criticall...

journal_title：Neuroscience letters

authors： Zacarias MS,Ramos AC,Alves DR,Galduróz JC

更新日期：2012-04-04 00:00:00

abstract：:Although abnormal processing of amyloid precursor protein (APP) leads to early onset of Alzheimer's disease, the normal function of this protein is poorly understood. APP is widely expressed in axons, dendrites, and synapses in both central and peripheral nervous systems. Mice homozygous for APP or its homologue APP-l...

journal_title：Neuroscience letters

authors： Yang G,Gong YD,Gong K,Jiang WL,Kwon E,Wang P,Zheng H,Zhang XF,Gan WB,Zhao NM

更新日期：2005-08-12 00:00:00

abstract：:Avoidance of the nicotine withdrawal syndrome as well as the positive subjective effects of nicotine is the major predisposing factor to motivate nicotine abuse. However, its underlying neurobehavioral mechanisms remain perplexing. In the present study, we investigated the influence of the neurosteroid allopregnanolon...

journal_title：Neuroscience letters

authors： Thakre PP,Tundulwar MR,Chopde CT,Ugale RR

更新日期：2013-04-29 00:00:00

abstract：:Auditory steady-state responses (ASSRs) are increasingly used in research of neuropsychiatric disorders and for brain-computer interface applications. However, results on attentional modulation of ASSRs are inconclusive. The evaluation of large-scale effects of task-related modulation on ASSRs might give better estima...

journal_title：Neuroscience letters

authors： Griskova-Bulanova I,Pipinis E,Voicikas A,Koenig T

更新日期：2018-05-01 00:00:00

abstract：:Odor-induced oscillatory signals have been reported in odor discrimination in various insects. To understand dynamic olfactory coding in the first order olfactory center, the antennal lobe, localization of oscillatory signals was investigated using an optical recording technique with a voltage-sensitive dye. We presen...

journal_title：Neuroscience letters

authors： Okada K,Kanzaki R

更新日期：2001-12-28 00:00:00

abstract：:Experimental Scrapie in hamster is a simple, reproducible model of prion diseases that occur in humans and animals. Stereotaxic microinoculation (0.5 microliter) of the agent (263 K) into a specific cerebral structure (striatum) in hamster, previously developed in our group, gives the opportunity to further investigat...

journal_title：Neuroscience letters

authors： Grégoire N,Lebrun F,Fahn L,Salamon G,Nicoli J

更新日期：1993-12-12 00:00:00

abstract：:In this study, we investigated two newly reported polymorphisms in association with late onset Alzheimer's disease (AD) in Chinese. They were a -491 A/T polymorphism in the Apolipoprotein E (APOE) promoter region and a five base pair deletion at exon 18 of alpha2-Macroglobin (A2M). There were 196 AD and 180 normal con...

journal_title：Neuroscience letters

authors： Chen L,Baum L,Ng HK,Chan LY,Sastre I,Artíga MJ,Valdivieso F,Bullido MJ,Chiu HF,Pang CP

更新日期：1999-07-16 00:00:00

abstract：:We have studied the electrophysiological properties of hippocampal neurons grown on surfaces of organic thin films formed on glass or silicon substrates and on microelectronic device surfaces in culture. Hippocampal neurons were dissociated from embryonic rats and plated on substrates chemically modified with laminin ...

journal_title：Neuroscience letters

authors： Offenhäusser A,Sprössler C,Matsuzawa M,Knoll W

更新日期：1997-02-14 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:Many recent studies have revealed the consistency of anticipatory postural adjustments preceding single leg movements, such as stepping, in standing humans. These adjustments appear to involve an active lateral transfer of weight to the stance leg. The present study demonstrates that these anticipatory adjustments oft...

journal_title：Neuroscience letters

authors： McIlroy WE,Maki BE

更新日期：1993-12-24 00:00:00

abstract：:2-Deoxy-d-glucose (2DG) is an analog of glucose that is effectively taken up by cells competing with normal glucose but cannot be further utilized to produce energy. It was previously reported that 2DG can mimic the beneficial effects of dietary restriction in experimental models of neurodegenerative disorders and can...

journal_title：Neuroscience letters

authors： Park M,Song KS,Kim HK,Park YJ,Kim HS,Bae MI,Lee J

更新日期：2009-01-16 00:00:00

abstract：:Sepsis-associated encephalopathy (SAE) has significant impact on the neurocognitive outcome of sepsis survivors. This study was conducted to analyze the amino-terminal propeptide of the C-type natriuretic peptide (NT-proCNP) as a biomarker for SAE in comparison to neuron-specific enolase (NSE) and S100B protein. Cereb...

journal_title：Neuroscience letters

authors： Ehler J,Saller T,Wittstock M,Rommer PS,Chappell D,Zwissler B,Grossmann A,Richter G,Reuter DA,Nöldge-Schomburg G,Sauer M

更新日期：2019-01-23 00:00:00

abstract：:Behavioral responses and neural responses in the somatosensory cortex were recorded in nine rabbits during the unpaired and paired treatments of classical eyeblink conditioning with a tone conditioned stimulus (CS) and an airpuff unconditioned stimulus. During the unpaired treatment, neither the behavioral nor neural ...

journal_title：Neuroscience letters

authors： Wikgren J,Ruusuvirta T,Korhonen T

更新日期：2003-05-01 00:00:00

abstract：:kappa-Opioid receptors were radiolabelled with the peptides [125I]dynorphin(1-8) and [3H]dynorphin(1-8) or with [3H]etorphine on guinea pig forebrain and cerebellar sections and visualized by quantitative autoradiography. All three radioligands yielded similar patterns of kappa-receptor localization. However, quantita...

journal_title：Neuroscience letters

authors： Sharif NA,Hunter JC,Hill RG,Hughes J

更新日期：1988-04-12 00:00:00

abstract：:Activation of the μ-opioid receptor (MOR) and noradrenaline reuptake inhibition (NRI) are well recognized as analgesic principles in acute and chronic pain indications. The novel analgesic tapentadol combines MOR agonism and NRI in a single molecule. The present study used OPRM1 (MOR) knockout (KO) mice to determine t...

journal_title：Neuroscience letters

authors： Kögel B,De Vry J,Tzschentke TM,Christoph T

更新日期：2011-03-17 00:00:00

abstract：:Recent findings from our and other laboratories indicate that cell cycle-related phenomena may play a key role in the formation of Alzheimer-type pathology and neuronal cell death in both Alzheimer's and cerebro-vascular diseases. In this study we examine the expression patterns of cyclins A, B1, D1 and E in neuronal ...

journal_title：Neuroscience letters

authors： Smith MZ,Nagy Z,Esiri MM

更新日期：1999-08-13 00:00:00

abstract：:1,3-di(2-[5-3H]tolyl)Guanidine ([3H]DTG) was found to bind to a single saturable population of binding sites in human cerebral cortex and NCB20 cells, a second low-affinity site was apparent in guinea pig brain. Displacement studies were performed to determine the pharmacology of the [3H]DTG binding site in these 3 me...

journal_title：Neuroscience letters

authors： Knight AR,Gillard J,Wong EH,Middlemiss DN

更新日期：1991-10-14 00:00:00

abstract：:Capsaicin, a neurotoxin which impairs some primary afferent nerve fibers, was locally applied to the mesenteric nerve trunks of adult guinea pigs. The effect of capsaicin was studied on contractile responses of the ileum to mesenteric nerve stimulation (20 Hz). Exposure of the mesenteric nerve to capsaicin (1 microM) ...

journal_title：Neuroscience letters

authors： Jin JG,Takaki M,Nakayama S

更新日期：1989-11-20 00:00:00

abstract：:Around 200,000 veterans (up to 32% of those deployed) of the 1991 Gulf War (GW) suffer from GW illness (GWI), which is characterized by multiple deficits in cognitive, affective, sensory and nociception domains. In this study we employed resting state fMRI (rsfMRI) to map impairments in brain function in GWI with adva...

journal_title：Neuroscience letters

authors： Gopinath KS,Sakoglu U,Crosson BA,Haley RW

更新日期：2019-05-14 00:00:00

abstract：:Human apolipoprotein E (apoE) exists in three major isoforms encoded by distinct alleles (APOE epsilon2, epsilon3 and epsilon4) and has important functions in nerve development and repair. Inheritance of the 4 allele is a major risk factor for the development of Alzheimer's disease. To investigate the role of APOE pol...

journal_title：Neuroscience letters

authors： Zetterberg H,Palmér M,Ricksten A,Poirier J,Palmqvist L,Rymo L,Zafiropoulos A,Arvanitis DA,Spandidos DA,Blennow K

更新日期：2002-05-24 00:00:00

abstract：:In order to clarify the mechanism of action of cerulenin analog, C75, known to suppress feeding behavior, food intake was measured in adult CD-1 male mice n=5 per group, treated i.p. with 10 and 20mg/kg of C75. Animals in both treatment groups had significantly lower 24h food consumption rate relative to the control g...

journal_title：Neuroscience letters

authors： Binienda ZK,Ross IA,Gough B,Riccio T,Kim CS,Ali SF

更新日期：2010-01-29 00:00:00

abstract：:Parkinson's disease (PD) is characterized by the selective loss of dopaminergic (DAergic) neurons in the substantia nigra and the subsequent depletion of dopamine (DA). This study assessed the protective effects of costunolide on DA-induced apoptosis in human DAergic SH-SY5Y cells, and its regulation of DA metabolism-...

journal_title：Neuroscience letters

authors： Ham A,Lee SJ,Shin J,Kim KH,Mar W

更新日期：2012-01-24 00:00:00

abstract：:We have previously shown that 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), an inhibitor of protein kinase C, inhibits proliferation of neuroblastoma cells in culture. We have now tested whether the effect of H7 is mediated by MAP kinase and Raf. It is shown that, in Neuro 2a cells, activation of protein kinase...

journal_title：Neuroscience letters

authors： Cabedo H,Felipo V,Miñana MD,Grisolía S

更新日期：1996-08-16 00:00:00