Anxiety-like behavior in the elevated-plus maze tests and enhanced IL-1β, IL-6, NADPH oxidase-1, and iNOS mRNAs in the hippocampus during early stage of adjuvant arthritis in rats.

abstract：:Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies we...

journal_title：Neuroscience letters

authors： Raja R,Rosenberg G,Caprihan A

更新日期：2019-02-16 00:00:00

abstract：:A comparison has been made of the effects of carbon monoxide (CO) or nitrogen (N2) exposure on synaptic transmission in the hippocampal slice. CA1 field potentials, evoked by Schaffer collateral stimulation, were unaffected by superfusion of slices with artificial cerebral spinal fluid (ACSF) equilibrated with either ...

journal_title：Neuroscience letters

authors： Doolette DJ,Kerr DI

更新日期：1992-04-13 00:00:00

abstract：:Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

journal_title：Neuroscience letters

authors： Zheng T,Li W,Zhang A,Altura BT,Altura BM

更新日期：1998-01-30 00:00:00

abstract：:Three variations of the in vitro neonatal rat spinal cord preparation were used to investigate motor responses to stimulation of the ventrolateral funiculus (VLF). In a partially hemisected spinal cord preparation, stimuli elicited frequency-dependent activity in lumbar ventral roots that outlasted the stimulus train ...

journal_title：Neuroscience letters

authors： Magnuson DS,Schramm MJ,MacLean JN

更新日期：1995-06-09 00:00:00

abstract：:The human visual system is divided into two pathways specialized for the processing of either objects or spatial locations. Neuroanatomical studies in monkeys have suggested that a similar specialization may also divide auditory cortex into two such pathways. We used the identical stimulus material in two experimental...

journal_title：Neuroscience letters

authors： Herrmann CS,Senkowski D,Maess B,Friederici AD

更新日期：2002-12-06 00:00:00

abstract：:This study examined c-Fos expression in selected brain areas consequent to intraperitoneal (IP) administration of saccharin and lithium chloride. Rats were tested for aversion to the saccharin as measured by flavor consumption and orofacial reactions in the taste reactivity (TR) test. It was found that intraperitoneal...

journal_title：Neuroscience letters

authors： Soto A,Gasalla P,Begega A,López M

更新日期：2017-04-24 00:00:00

abstract：:Bath application of alpha-melanocyte stimulating hormone (alpha-MSH) to rat hypothalamic slices inhibited the spontaneous firing rate of continuously firing neurons in the ventromedial hypothalamic nucleus or paraventricular nucleus. This inhibitory effect is most likely direct and independent of synaptic transmission...

journal_title：Neuroscience letters

authors： Fong TM,Van der Ploeg LH

更新日期：2000-03-31 00:00:00

abstract：:The effects of histamine (HA) on the resting membrane potential and input resistance of rat medial vestibular nucleus (MVN) neurons were investigated using intracellular recording techniques from a submerged brain slice preparation. The exogenous application of HA predominantly produced a concentration-dependent membr...

journal_title：Neuroscience letters

authors： Phelan KD,Nakamura J,Gallagher JP

更新日期：1990-02-16 00:00:00

abstract：:Purkinje cell degeneration (pcd) mutant mice lose cerebellar Purkinje cells. It was found that pcd mice, contrary to normal mice, did not alternate spontaneously at any of 3 inter-trial intervals (15 s, 3 or 6 min). Deficits in spontaneous alternation are typical of animals with brain damage in areas important in spat...

journal_title：Neuroscience letters

authors： Lalonde R,Manseau M,Botez MI

更新日期：1987-10-05 00:00:00

abstract：:To evaluate the roles of complement in kainic acid (KA)-induced neuronal damages, the immunohistochemical localization of the complement protein C3 was examined in rat hippocampus after systemic KA injection. The immunoreactivity for C3 was found in glial cells in control rats, and such glial cells were increased in n...

journal_title：Neuroscience letters

authors： Morita H,Suzuki K,Mori N,Yasuhara O

更新日期：2006-11-27 00:00:00

abstract：:To test if nitric oxide (NO) is involved in modulation of neuronal activity after global changes of brain function, nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) reactivity in the cerebellar cortex was compared in monkeys maintained under anaesthesia for 24-48 h with others only anaesthetised for pe...

journal_title：Neuroscience letters

authors： Yan XX,Garey LJ

更新日期：1997-07-18 00:00:00

abstract：:The potassium-chloride cotransporter 2 (KCC2)-dependent intracellular chloride level determines whether neurons respond to GABA and/or glycine by depolarization or hyperpolarization. However, still unknown is the role of KCC2-dependent chloride homeostasis in regulating the spontaneous activity of neuronal circuits vi...

journal_title：Neuroscience letters

authors： Wang W,Xu TL

更新日期：2006-10-02 00:00:00

abstract：:Rhythmic arm movement significantly suppresses H-reflex amplitude in the soleus (SOL) muscle. This is evidence of neural linkages between the arms and legs which can be exploited during locomotion and have been ascribed to the descending effects of CPGs for arm cycling. However, the generalizability of the effects of ...

journal_title：Neuroscience letters

authors： Dragert K,Zehr EP

更新日期：2009-02-06 00:00:00

abstract：:In the experiments described in the present report, we evaluated the effects of ethanol on the activity of GABAA receptors of cerebellar granule cells in culture. Only very high ethanol concentrations (100-300 mM) showed a clear and significant stimulatory effect on the activity of such receptors. This result was unex...

journal_title：Neuroscience letters

authors： Casagrande S,Cupello A,Pellistri F,Robello M

更新日期：2007-03-13 00:00:00

abstract：:Evidence, based on voltage-clamp and current-clamp recording, is presented for endogenous receptors for vasoactive intestinal polypeptide (VIP) on the cell membrane of the Xenopus oocyte. At normal resting potential a hyperpolarisation is produced by VIP, associated with an increase in K+ conductance. The response is ...

journal_title：Neuroscience letters

authors： Reale V,Ashford ML,Barnard EA

更新日期：1987-12-16 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease characterized by degeneration and death of motor neurons. Aberrant protein aggregation and oxidative stress are implicated in the etiology of ALS; thus preventing propagation of early aggregation events and oxidative damage could be an...

journal_title：Neuroscience letters

authors： Evans TM,Bhattacharya A,Shi Y,Qi W,Block TJ,Chaudhuri A,Chaudhuri AR,Hawker K,Van Remmen H

更新日期：2016-06-15 00:00:00

abstract：:In this study, we have investigated the release of immunoreactive interleukin-1 beta (irIL-1 beta) from the rat hypothalamus in vitro. It was found that (1) tissue explants release sizable amounts of irIL-1 beta (ranging from 0.43 to 0.52 pg/mg of wet tissue) in 20 min incubations; (2) basal release in significantly i...

journal_title：Neuroscience letters

authors： Tringali G,Mancuso C,Mirtella A,Pozzoli G,Parente L,Preziosi P,Navarra P

更新日期：1996-11-29 00:00:00

abstract：:Sickle cell disease (SCD) describes a group of disorders associated with a point mutation in the beta chain of hemoglobin. The mutation leads to the creation of sickle hemoglobin (HbS) and causes distortion of erythrocytes through polymerization under low oxygen, resulting in characteristic sickle red blood cells. Vas...

journal_title：Neuroscience letters

authors： Uhelski ML,Simone DA

更新日期：2019-07-13 00:00:00

abstract：:Activations of the DLPFC and SMA have been shown to correlate with dual-task walking. However, very few investigations have directly perturbed the activations of these areas to establish a cause-and-effect relationship. The objectives of this study were: 1) to investigate the role of DLPFC and SMA in dual-task walking...

journal_title：Neuroscience letters

authors： Goh HT,Ewing S,Marchuk D,Newton A,Nyangani I

更新日期：2019-04-17 00:00:00

abstract：:Glucose homeostasis was studied in the spontaneously hypertensive rat (SHR). The fasting plasma glucose levels were similar in the SHR and normotensive Wistar-Kyoto (WKY) rat (102.7+/-2.4 vs. 107.4+/-4.2 mg/dl, P > 0.01). One hour after glucose challenge, the plasma glucose level was slightly but insignificantly incre...

journal_title：Neuroscience letters

authors： Tong YC,Wang CJ,Cheng JT

更新日期：1997-09-19 00:00:00

abstract：:The AMPA receptor subunit GluR2 is downregulated in neurons following a wide range of neurological insults. Here we report that suppression of GluR2 gene promoter activity is associated with kainate (KA)-induced downregulation of GluR2 subunit levels in primary cultured cortical neurons. RT-PCR and Northern blotting s...

journal_title：Neuroscience letters

authors： Jia YH,Zhu X,Li SY,Ni JH,Jia HT

更新日期：2006-07-31 00:00:00

abstract：:We describe the measurement of beta-nerve growth factor (NGF) content in cerebrospinal fluid (CSF) from multiple sclerosis (MS) patients compared with CSF from age-matched normal subjects using a specific sandwich immunoassay (ELISA). During acute attacks patients exhibit a significant increase of NGF content compared...

journal_title：Neuroscience letters

authors： Laudiero LB,Aloe L,Levi-Montalcini R,Buttinelli C,Schilter D,Gillessen S,Otten U

更新日期：1992-11-23 00:00:00

abstract：:Apolipoprotein(a) [apo(a)] is a highly polymorphic glycoprotein which has been suggested to play a role in Alzheimer's disease (AD). Plasma lipoprotein(a) [Lp(a)] levels and the differential expression of apo(a) isoforms were analyzed in 73 sporadic AD patients compared with 73 age- and gender-matched healthy controls...

journal_title：Neuroscience letters

authors： Emanuele E,Peros E,Tomaino C,Feudatari E,Bernardi L,Binetti G,Maletta R,D'Angelo A,Montagna L,Bruni AC,Geroldi D

更新日期：2004-02-26 00:00:00

abstract：:We examined the effect of lateral (visceral) and medial (gustatory) parabrachial nucleus (PBN) lesions on the suppression of milk intake induced with cholecystokinin (CCK) in 24 h food-deprived rats. Irrespective of CCK dose, each type of PBN lesion significantly elevated the consumption of milk. Neither medial nor la...

journal_title：Neuroscience letters

authors： Trifunovic R,Reilly S

更新日期：2003-09-11 00:00:00

abstract：:The rat spinal cord slice preparation has been used to investigate the sensitivity of deep dorsal horn neurones to the excitatory amino acids N-methyl-D-aspartate (NMDA), quisqualate and L-glutamate. Intracellular recordings were made from 44 neurones in laminae III-VI of 14- to 16-day rats. Superfusion of quisqualate...

journal_title：Neuroscience letters

authors： King AE,Thompson SW,Urban L,Woolf CJ

更新日期：1988-07-08 00:00:00

abstract：:DJ-1, the causative gene of a familial form of Parkinson's disease (PD), has been reported undergo oxidation preferentially at the 106th cysteine residue (Cys-106) under oxidative stress. Recently, it has been found that the levels of oxidized DJ-1 in erythrocytes of unmedicated PD patients are markedly higher than th...

journal_title：Neuroscience letters

authors： Akazawa YO,Saito Y,Hamakubo T,Masuo Y,Yoshida Y,Nishio K,Shichiri M,Miyasaka T,Iwanari H,Mochizuki Y,Kodama T,Noguchi N,Niki E

更新日期：2010-10-15 00:00:00

abstract：:The binding site for 1,4-benzodiazepines in the brain is part of the hetero-oligomeric gamma-aminobutyric acid (GABA)A receptor complex which regulates a chloride ion channel. The presence of the gamma 2 subunit in the complex is necessary for the binding of benzodiazepines to their binding site. This study demonstrat...

journal_title：Neuroscience letters

authors： Karle J,Witt MR,Nielsen M

更新日期：1995-12-29 00:00:00

abstract：:Supporting cell mitosis contributes significantly to hair cell regeneration in the acoustically damaged bird inner ear. Yet there may be another mechanism of hair cell replacement: supporting cell conversion. This study used cytosine arabinoside (Ara-C), an inhibitor of DNA synthesis, to better determine whether suppo...

journal_title：Neuroscience letters

authors： Adler HJ,Raphael Y

更新日期：1996-02-16 00:00:00

abstract：:Mice were treated with N-2-chloroethyl-N-ethyl-2-bromobenzylamine hydrochloride (DSP4), which causes severe noradrenaline (NA) depletions in brain regions and the spinal cord, or vehicle i.p. They were tested 14 days later for antinociception induced by intrathecal injections of different doses of NA. A potentiation o...

journal_title：Neuroscience letters

authors： Post C,Arweström E,Minor BG,Wikberg JE,Jonsson G,Archer T

更新日期：1985-08-16 00:00:00

abstract：:The regional cerebral blood flow (rCBF) was measured with positron emission tomography in eight normal volunteers with the purpose of measuring rCBF changes related to the comprehension of an unfamiliar spoken languages. When attempting to comprehend the meaning of words, the left hemisphere showed dominant increases ...

journal_title：Neuroscience letters

authors： Kawashima R,Itoh M,Hatazawa J,Miyazawa H,Yamada K,Matsuzawa T,Fukuda H

更新日期：1993-10-14 00:00:00