Only high concentrations of ethanol affect GABAA receptors of rat cerebellum granule cells in culture.

abstract：:The molecular regulation of seizure-induced neuronal death may involve interactions between proteins of the Bcl-2 and 14-3-3 families. To further examine these pathways we performed subcellular fractionation on hippocampi obtained following a brief period of status epilepticus in the rat. Western blotting determined s...

journal_title：Neuroscience letters

authors： Schindler CK,Shinoda S,Simon RP,Henshall DC

更新日期：2004-02-19 00:00:00

abstract：:Phencyclidine (PCP) abuse is reaching alarming proportions. PCP has recently been shown to induce hypertensive encephalopathies, microvascular cerebrovasospasm and acute intracerebral hemorrhage. Since we have shown in vitro that cerebral vasospasms induced by PCP could be completely reversed, or prevented, by use of ...

journal_title：Neuroscience letters

authors： Huang QF,Gebrewold A,Altura BT,Altura BM

更新日期：1990-05-18 00:00:00

abstract：:The effects of free fatty acids (FFAs) on growth hormone releasing hormone (GHRH) secretion by fetal rat cortical and hypothalamic neurons in monolayer culture have been investigated. Treatment with caprylic or oleic acids for 90 min, induced a dose-dependent increase in GHRH secretion. The stimulatory effect of capry...

journal_title：Neuroscience letters

authors： Señaris RM,Lewis MD,Lago F,Dominguez F,Scanlon MF,Dieguez C

更新日期：1992-01-20 00:00:00

abstract：:Neuronal cell cycle activation has been implicated in neurodegenerative diseases such as Alzheimer's disease, while the initiating mechanism of cell cycle activation remains to be determined. Interestingly, our previous studies have shown that cell cycle activation by c-Myc (Myc) leads to neuronal cell death which sug...

journal_title：Neuroscience letters

authors： Lee HP,Kudo W,Zhu X,Smith MA,Lee HG

更新日期：2011-11-14 00:00:00

abstract：:We describe a new model of neurogenic pulmonary edema in spinal cord injured Wistar male rats. The pulmonary edema was elicited by an epidural thoracic balloon compression spinal cord lesion, performed under a low concentration of isoflurane (1.5 or 2%) in air. Anesthesia with 1.5% isoflurane promoted very severe inte...

journal_title：Neuroscience letters

authors： Sedý J,Urdzíková L,Likavcanová K,Hejcl A,Jendelová P,Syková E

更新日期：2007-08-16 00:00:00

abstract：:Following virus infection of the central nervous system, microglia become activated and undergo morphological as well as functional transformations, thereby initiating effective antiviral actions. Herein, we have examined the contribution of nuclear factor kappaB (NF-kappaB) and mitogen-activated protein kinase (MAPK)...

journal_title：Neuroscience letters

authors： Nakamichi K,Saiki M,Kitani H,Kuboyama Y,Morimoto K,Takayama-Ito M,Kurane I

更新日期：2007-03-13 00:00:00

abstract：:The accumulation of choline acetyltransferase (CAT) proximal to and nerve growth factor (NGF) distal to the intraneural site of tetrodotoxin (TTX) or batrachotoxin (BTX) injection in vivo was used to monitor orthograde and retrograde axonal transport. Orthograde axonal transport was blocked by BTX for up to 7-10 days ...

journal_title：Neuroscience letters

authors： Boegman RJ,Riopelle RJ

更新日期：1980-06-01 00:00:00

abstract：:Inflammation is an important contributor to the development of Alzheimer's disease (AD). Anti-inflammatory medication may offer promising treatment for AD. Hydroxy-safflor yellow A (HSYA), a chemical component of the safflower yellow pigments, has been reported to exert potent immunosuppressive effects. This study exa...

journal_title：Neuroscience letters

authors： Zhang Z,Wu Z,Zhu X,Hui X,Pan J,Xu Y

更新日期：2014-03-06 00:00:00

abstract：:The objective of the study was to investigate the presence and distribution of nerve cell bodies and small ganglia in the stroma of human submandibular gland. A retrospective immunohistochemical study in 13 human submandibular glands, fixed in neutral buffered formalin and embedded in paraffin wax, was undertaken. Six...

journal_title：Neuroscience letters

authors： Tosios KI,Nikolakis M,Prigkos AC,Diamanti S,Sklavounou A

更新日期：2010-05-07 00:00:00

abstract：:The aim was to examine the effect of handball training on cognitive ability in elderly with mild cognitive impairment. A total of 60 elderly were randomly divided into training group (n=30) and control group (n=30). The mini-mental state examination (MMSE) score and abilities of daily living scale (ADL) score before, ...

journal_title：Neuroscience letters

authors： Wei XH,Ji LL

更新日期：2014-04-30 00:00:00

abstract：:Repeated exposure to dizocilpine (MK-801) can be used as a model of schizophrenia that incorporates disease progression. Proton magnetic resonance spectroscopy (1H MRS) has been widely used to investigate schizophrenia-related alterations in glutamate (Glu). The purpose of this study was to investigate metabolic alter...

journal_title：Neuroscience letters

authors： Yoo CH,Song KH,Lim SI,Lee DW,Woo DC,Choe BY

更新日期：2017-01-10 00:00:00

abstract：:Experiments were performed to test several predictions of the hypothesis that activity pattern-dependent changes in intracellular free calcium concentration ([Ca2+]i) might play a role in the translation of altered patterns of neuronal activity into changes in neurotransmitter gene expression. It was shown that (1) th...

journal_title：Neuroscience letters

authors： Hodaie M,Jeevaratnam P,Salter MW,Roach A

更新日期：1995-02-13 00:00:00

abstract：:It is well-established that 17beta-estradiol (17beta-E(2)) confers neuroprotection to male and female rats exposed to focal cerebral ischemia, while less is known about the effects of the hormone under conditions of transient global ischemia. Since translocation of cytochrome c from the mitochondria to the cytosol is ...

journal_title：Neuroscience letters

authors： Bagetta G,Chiappetta O,Amantea D,Iannone M,Rotiroti D,Costa A,Nappi G,Corasaniti MT

更新日期：2004-09-16 00:00:00

abstract：:The aim of this study was to investigate the adaptive process in the coupling between visual information and body sway in children postural control. Twenty-seven children from 4-, 8- and 12-year-olds and ten adults stood upright inside of a moving room. In the first 2 min, the room was moved continuously at frequency ...

journal_title：Neuroscience letters

authors： Rinaldi NM,Polastri PF,Barela JA

更新日期：2009-12-31 00:00:00

abstract：:In vivo rates of incorporation and turnover of palmitate and arachidonate in brain phospholipids were measured in awake rats treated chronically with lithium, following intravenous infusion of radiolabeled palmitate and arachidonate, respectively. Chronic lithium, at a brain level considered to be therapeutic in human...

journal_title：Neuroscience letters

authors： Chang MC,Grange E,Rabin O,Bell JM,Allen DD,Rapoport SI

更新日期：1996-12-20 00:00:00

abstract：:Microelectrode recordings from the somata of rat dorsal root ganglion (DRG) cells were used to correlate their electrophysiological characteristics with sensitivity to locally applied capsaicin. Of the 80 cells tested, 17 responded to capsaicin by a rapid depolarization. These cells had low axonal conduction velocitie...

journal_title：Neuroscience letters

authors： Heyman I,Rang HP

更新日期：1985-05-01 00:00:00

abstract：:Superfusion of the isolated spinal cord of neonatal rats (4-9 days postpartum) with physiological medium containing 2-chloroadenosine (2-CA) or anoxic medium (equilibrated with 95% N2-5% CO2) depressed the evoked monosynaptic reflex (MSR) recorded extracellularly from a ventral spinal root. The effectiveness of 2-CA o...

journal_title：Neuroscience letters

authors： Lloyd HG,Perkins A,Spence I

更新日期：1989-06-19 00:00:00

abstract：:Emotions organize human and animal behaviour by automatically adjusting their actions at multiple physiological and behavioural scales. Recently, pattern recognition techniques have emerged as an important tool for quantifying the neural, physiological, and phenomenological organization of emotions in humans. Here we ...

journal_title：Neuroscience letters

authors： Nummenmaa L,Saarimäki H

更新日期：2019-02-06 00:00:00

abstract：:8-Hydroxy-2-[di-n-propylamino]-tetralin) (8-OH-DPAT), a 5-HT1A/7 receptor agonist, has a chronobiological effect on the circadian system. To identify how the 8-OH-DPAT exerts this effect, we specifically destroyed the serotonergic (5-HT) fibres connecting the median raphe nuclei (RN) to the suprachiasmatic nuclei (SCN...

journal_title：Neuroscience letters

authors： Schuhler S,Saboureau M,Pitrosky B,Pévet P

更新日期：1998-10-30 00:00:00

abstract：:A FORTRAN computer program is described which enables solution of a set of partial differential equations describing synaptic transmission, including neurotransmitter diffusion, binding to receptors on the postsynaptic membrane with subsequent formation of open ion-conducting channels, and hydrolysis. Integration is p...

journal_title：Neuroscience letters

authors： Madsen BW,Edeson RO,Lam HS,Milne RK

更新日期：1984-07-13 00:00:00

abstract：:Samples of human cerebral cortex were stained immunocytochemically for tyrosine hydroxylase (TH) and gamma-aminobutyric acid (GABA). TH-positive neurons were in small number and predominated in the deep infragranular layers V-VI contrasting with numerous GABA-positive neurons scattered in all layers. Co-localization o...

journal_title：Neuroscience letters

authors： Trottier S,Geffard M,Evrard B

更新日期：1989-11-20 00:00:00

abstract：:Cultured embryonic mouse olfactory bulb cells formed asymmetric, symmetric, axodendritic, and dendrodendritic synapses. These neurons contained electron lucent, dense core, and coated vesicles. Dense core and coated vesicles had an average diameter of 71 and 80 nm, respectively. Two statistically different populations...

journal_title：Neuroscience letters

authors： Fracek SP Jr,Guo L,Schafer R

更新日期：1994-04-11 00:00:00

abstract：:Spinal cord injury (SCI) triggers pronounced inflammatory responses that are accompanied by neuronal disruption and functional deficits. SCI treatment remains an unmet clinical need. Emerging evidence suggests that riluzole may exert a neuroprotective effect due to its anti-inflammatory properties. However, details of...

journal_title：Neuroscience letters

authors： Wu Q,Zhang Y,Zhang Y,Zhang W,Zhang W,Liu Y,Xu S,Guan Y,Chen X

更新日期：2020-04-01 00:00:00

abstract：:We used physiological and anatomical methods to elucidate how the visual field is represented in the part of the dorsal anterior thalamus of the leopard frog that receives direct retinal projections. We recorded extracellularly while presenting visual stimuli, and characterized a physiologically defined region that en...

journal_title：Neuroscience letters

authors： Skorina LK,Recktenwald EW,Dudkin EA,Saidel WM,Gruberg ER

更新日期：2016-05-16 00:00:00

abstract：:Sorbitol accumulation and transmembrane efflux in JS1 schwannoma cells were examined during osmotic stress in the presence of a sorbitol dehydrogenase (SD) inhibitor and following return to iso-osmotic conditions. SD inhibition promoted sorbitol accumulation under hyperglycemic and/or hyperosmotic conditions, and sorb...

journal_title：Neuroscience letters

authors： Mizisin AP,Li L,Calcutt NA

更新日期：1997-06-20 00:00:00

abstract：:There is evidence that immune-inflammatory, stress of reactive oxygen and nitrogen species (IO&NS) processes play a role in the neurodegenerative processes observed in Parkinson's disease (PD). The aim of the present study was to investigate peripheral IO&NS biomarkers in PD. We included 56 healthy individuals and 56 ...

journal_title：Neuroscience letters

authors： de Farias CC,Maes M,Bonifácio KL,Bortolasci CC,de Souza Nogueira A,Brinholi FF,Matsumoto AK,do Nascimento MA,de Melo LB,Nixdorf SL,Lavado EL,Moreira EG,Barbosa DS

更新日期：2016-03-23 00:00:00

abstract：:The effects of severe hypoglycemia on perforant path-evoked field potentials were examined in the rat hippocampus. Although a complete loss of this response was noted when blood glucose concentration fell below 1 mM, this occurred before cessation of electroencephalogram (EEG) activity. Both spontaneous and evoked res...

journal_title：Neuroscience letters

authors： Butcher SP,Jacobson I,Sandberg M,Hagberg H,Hamberger A

更新日期：1987-05-19 00:00:00

abstract：:Diazoxide is a putative mitochondrial, ATP-sensitive potassium channel opener that has been implicated in neuroprotection in cerebral ischemia. Administered as pretreatment, diazoxide can attenuate ischemia-related neuronal injury, but little is known about the potential neuroprotective properties of the drug when it ...

journal_title：Neuroscience letters

authors： Farkas E,Timmer NM,Domoki F,Mihály A,Luiten PG,Bari F

更新日期：2005-10-28 00:00:00

abstract：:We investigated laminin beta1 expression in the hippocampi of patients with intractable epilepsy and explored the role of laminin beta1 in the pathogenesis of this condition. Fluorescence quantitative PCR, immunofluorescence, immunohistochemistry and Western blotting were used to measure laminin beta1 expression in su...

journal_title：Neuroscience letters

authors： Wu Y,Wang XF,Mo XA,Sun HB,Li JM,Zeng Y,Lin T,Yuan J,Xi ZQ,Zhu X,Zheng JO

更新日期：2008-10-10 00:00:00

abstract：:Global cerebral ischemia-reperfusion (GCI/R) may occur after any of several clinical conditions such as cardiac arrest and anesthetic accident. Some dopamine receptor agonists possess neuroprotective effects. However, some of them may produce side effects during treatment. Piribedil, which is a dopamine D2/D3 receptor...

journal_title：Neuroscience letters

authors： Wang W,Liu L,Chen C,Jiang P,Zhang T

更新日期：2018-09-25 00:00:00