当前位置： SCI文献检索 > NEUROSCIENCE LETTERS期刊下所有文献 > 2-Amino-5-phosphonovalerate attenuates the severe hypoglycemia-induced loss of perforant path-evoked field potentials in the rat hippocampus.

2-Amino-5-phosphonovalerate attenuates the severe hypoglycemia-induced loss of perforant path-evoked field potentials in the rat hippocampus.

Abstract：

:The effects of severe hypoglycemia on perforant path-evoked field potentials were examined in the rat hippocampus. Although a complete loss of this response was noted when blood glucose concentration fell below 1 mM, this occurred before cessation of electroencephalogram (EEG) activity. Both spontaneous and evoked responses recovered partially following glucose readministration. D-2-Amino-5-phosphonovalerate, an NMDA-sensitive acidic amino acid receptor antagonist, facilitated this recovery from the hypoglycemic challenge when administered via a dialysis probe.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Butcher SP,Jacobson I,Sandberg M,Hagberg H,Hamberger A

doi

10.1016/0304-3940(87)90418-6

subject

Has Abstract

pub_date

1987-05-19 00:00:00

pages

296-300

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(87)90418-6

journal_volume

76

pub_type

杂志文章

相关文献

NEUROSCIENCE LETTERS文献大全
  • Glutamate but not interleukin-6 influences the phosphorylation of tau in primary rat hippocampal neurons.

    abstract：:Alzheimer's disease (AD) is characterized by amyloid plaques, neuritic degenerations, disturbed glutamatergic neurotransmission and a peculiar inflammatory response. Diffuse plaques develop into neuritic plaques when neurites undergo degeneration in the plaque area. Hyperphosphorylation of tau proteins is a major step...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(98)01003-9

    authors： Hüll M,Eistetter J,Fiebich BL,Bauer J

    更新日期：1999-02-12 00:00:00

  • Mode of action of a sympathomimetic amine, paramethoxyphenylethylamine (PMPEA) in the mouse CNS: Release of biogenic amines.

    abstract：:Paramethoxyphenylethylamine (PMPEA) is a sympathomimetic amine, like its parent compound, phenylethylamine. The intraperitoneal administration of PMPEA to mice produces a dose-dependent depletion of brain and heart norepinephrine, with significant reduction being observed one hour postinjection. At lower dosages, PMPE...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(75)90033-6

    authors： Ashkenazi R,Haber B

    更新日期：1975-09-01 00:00:00

  • The formation of bioactive amyloid species by prion proteins in vitro and in cells.

    abstract：:Amyloid proteins are a group of proteins that can polymerize into cross beta-sheeted amyloid species. We have found that enhancing cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) formazan exocytosis is a common property of bioactive amyloid species formed from all of the amyloid proteins te...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2006.07.047

    authors： Liu Y,Ritter C,Riek R,Schubert D

    更新日期：2006-10-09 00:00:00

  • Why do so many genetic insults lead to Purkinje Cell degeneration and spinocerebellar ataxia?

    abstract：:The genetically heterozygous spinocerebellar ataxias are all characterized by cerebellar atrophy and pervasive Purkinje Cell degeneration. Up to date, more than 35 functionally diverse spinocerebellar ataxia genes have been identified. The main question that remains yet unsolved is why do some many genetic insults lea...

    journal_title：Neuroscience letters

    pub_type： 杂志文章,评审

    doi：10.1016/j.neulet.2018.02.004

    authors： Huang M,Verbeek DS

    更新日期：2019-01-01 00:00:00

  • Stability and variability of acoustically specified coordination patterns while walking side-by-side on a treadmill: does the seagull effect hold?

    abstract：:To examine whether the Haken-Kelso-Bunz model for rhythmic interlimb coordination applies to walking side-by-side on a treadmill, we invited six pairs of participants to coordinate their stepping movements at seven prescribed relative phases (between 0 degrees and 180 degrees ) to scan the attractor layout governing t...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2010.03.008

    authors： van Ulzen NR,Lamoth CJ,Daffertshofer A,Semin GR,Beek PJ

    更新日期：2010-04-26 00:00:00

  • Spinal opioid receptors and inhibition of urinary bladder motility in vivo.

    abstract：:The effects of intrathecal injections of morphine and other opioid receptor selective drugs were tested on urinary bladder contractions in the anesthetized rat. Morphine produced dose-related inhibition of bladder motility which was abolished by naloxone. This action was also observed with mu- and delta-opioid recepto...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(84)90390-2

    authors： Dray A,Metsch R

    更新日期：1984-06-01 00:00:00

  • Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat.

    abstract：:Mitochondrial dysfunction and oxidative stress are often linked to various neurodegenerative disorders including ischemic stroke and Huntington's disease (HD). S-Nitrosoglutathione (GSNO) is an endogenous nitric oxide carrier recently identified as a potent antioxidant capable of neutralizing oxidative stress. In the ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2004.03.028

    authors： Ju TC,Yang YT,Yang DI

    更新日期：2004-05-27 00:00:00

  • Variation of variable number of tandem repeat sequences in the 3'-untranslated region of primate dopamine transporter genes that affects reporter gene expression.

    abstract：:Genetic polymorphism has been reported in the 3'-untranslated region (3'-UTR) of the human dopamine transporter (DAT) gene and the variable number of tandem repeat (VNTR) polymorphism has been proposed to be associated with normal personal traits or psychoneurological disorders. To assess the variation of this region ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/s0304-3940(02)01125-4

    authors： Inoue-Murayama M,Adachi S,Mishima N,Mitani H,Takenaka O,Terao K,Hayasaka I,Ito S,Murayama Y

    更新日期：2002-12-16 00:00:00

  • Olfactory abnormalities in anxiety disorders.

    abstract：:The olfactory system plays an important role in both animal and human anxiety reactions. However, results on olfactory performance during the course of clinical anxiety disorders remain scarce. Therefore, we conducted an exploratory pilot study in 17 patients currently diagnosed with an anxiety disorder. Patients part...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2012.01.034

    authors： Clepce M,Reich K,Gossler A,Kornhuber J,Thuerauf N

    更新日期：2012-03-05 00:00:00

  • Effect of different regions of Nogo-A on the differentiation of neural progenitors.

    abstract：:Nogo-A is an inhibitor of neurite outgrowth and axonal regeneration after CNS injury. Several functional regions including Nogo-66 were identified to mediate the inhibitory effect of Nogo-A. We have reported that Nogo-66 could promote neural progenitors to differentiate into glial cells. Here we exam three other regio...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.04.034

    authors： Gao Y,Xiao Z,Chen B,Wang B,Han J,Zhao Y,Zhang J,Dai J

    更新日期：2009-07-24 00:00:00

  • Mast cells in nerve end neuromas of mice.

    abstract：:The volume density of mast cells was estimated in nerve end neuromas at various time-points after transection of the left sciatic nerve of 6-week-old mice. After an initial reduction in the amount of mast cells there was a steady increase with numerous cells in 6-month-old neuromas. The variation in amount of mast cel...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(86)90497-0

    authors： Nennesmo I,Reinholt F

    更新日期：1986-09-12 00:00:00

  • Chronic stroke and aging: the impact of acoustic stimulus intensity on fractionated reaction time.

    abstract：:In control samples, intense acoustic "go" stimuli accelerate the central and peripheral motor processes that compose simple reaction time movements. The goal of the current study was to determine whether movements that are initiated to intense acoustic cues facilitate simple reaction times in (1) adults with chronic s...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.01.041

    authors： Coombes SA,Janelle CM,Cauraugh JH

    更新日期：2009-03-13 00:00:00

  • Effect of baicalein from Scutellaria baicalensis on prevention of noise-induced hearing loss.

    abstract：:Noise-induced hearing loss (NIHL) has been thought to primarily involve damage to the sensory hair cells of the cochlea via mechanical and metabolic mechanisms. This study examined the effects of baicalin, baicalein, and Scutellaria baicalensis (SB) extract against NIHL in a mouse model. Mice received oral treatment w...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.12.009

    authors： Kang TH,Hong BN,Park C,Kim SY,Park R

    更新日期：2010-01-29 00:00:00

  • Enhanced blink reflex recovery in juvenile myoclonic epilepsy.

    abstract：:Juvenile myoclonic epilepsy (JME), which has been attributed to the dysfunction of cortico-thalamic pathway, has been considered to be one of the system epilepsies. However, electrophysiological and functional neuroimaging techniques have revealed the functional involvement of various parts of the central nervous syst...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2015.10.025

    authors： Kandemir M,Gündüz A,Uzun N,Yeni SN,Kızıltan ME

    更新日期：2015-11-16 00:00:00

  • Sleep-promoting action of IIK7, a selective MT2 melatonin receptor agonist in the rat.

    abstract：:Several novel melatonin receptor agonists, in addition to various formulations of melatonin itself, are either available or in development for the treatment of insomnia. Melatonin is thought to exert its effects principally through two high affinity, G-protein coupled receptors, MT1 and MT2, though it is not known whi...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2009.04.005

    authors： Fisher SP,Sugden D

    更新日期：2009-06-26 00:00:00

  • C3a expressed in the central nervous system protects against LPS-induced shock.

    abstract：:Complement is implicated in the pathogenesis of inflammatory disorders of the central nervous system (CNS), like multiple sclerosis, Alzheimer's disease, and trauma. The anaphylatoxins C3a and C5a are thought to be the major contributors to complement-mediated inflammation in the CNS, likely mediating their effects vi...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2005.07.015

    authors： Boos L,Szalai AJ,Barnum SR

    更新日期：2005-10-21 00:00:00

  • Effects of chewing in working memory processing.

    abstract：:It has been generally suggested that chewing produces an enhancing effect on cognitive performance-related aspects of memory by the test battery. Furthermore, recent studies have shown that chewing is associated with activation of various brain regions, including the prefrontal cortex. However, little is known about t...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2008.03.033

    authors： Hirano Y,Obata T,Kashikura K,Nonaka H,Tachibana A,Ikehira H,Onozuka M

    更新日期：2008-05-09 00:00:00

  • Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTP.

    abstract：:Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder. Epidemiological studies suggest that the exposure of the herbicide glyphosate may influence the development of PD in humans. In this study, we examined whether the exposure of glyphosate can affect the reduction of dopamine transporter (...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2020.135032

    authors： Pu Y,Chang L,Qu Y,Wang S,Tan Y,Wang X,Zhang J,Hashimoto K

    更新日期：2020-06-21 00:00:00

  • Tetrahydrobiopterin-dependent production of L-dopa in NRK fibroblasts transfected with tyrosine hydroxylase cDNA: future use for intracerebral grafting.

    abstract：:In the present study, tyrosine hydroxylase (TH; EC 1.14.16.2) cDNA was transfected into cultured fibroblasts and the production of L-3,4-dihydroxyphenylalanine (L-DOPA) was determined. Type 2 TH cDNA was transfected into fibroblasts (NRK-49F) derived from the normal rat kidney, and the expression of the TH minigene wa...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(90)90008-w

    authors： Uchida K,Ishii A,Kaneda N,Toya S,Nagatsu T,Kohsaka S

    更新日期：1990-02-16 00:00:00

  • Developmental delays associated with prenatal alcohol exposure are reversed by thyroid hormone treatment.

    abstract：:Exposure to alcohol in utero has been associated with hypothyroidism and a variety of developmental defects characteristic of thyroid dysfunction. The present work examined whether these abnormalities could be reversed in infant rats treated with thyroid hormones. Subjects were offspring of dams which were on the foll...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(90)90535-h

    authors： Gottesfeld Z,Silverman PB

    更新日期：1990-02-05 00:00:00

  • Acetylcholine activates a nicotinic receptor and an inward current in dorsal motor nucleus of the vagus neurons in vitro.

    abstract：:This study examines the effect of acetylcholine (Ach) on parasympathetic vagal neurons in the dorsal motor nucleus of the vagus (DMNX). Patch-clamp techniques were utilized to examine voltage and ligand-gated currents in visualized DMNX neurons in an in vitro slice. Ach (100 microM) activated an inward current, -196.4...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(95)11807-9

    authors： Neff RA,Hansen MK,Mendelowitz D

    更新日期：1995-08-11 00:00:00

  • Reinnervation after destruction of the dopaminergic system in the rat nucleus accumbens: a quantitative immunohistochemical analysis.

    abstract：:The recurrence of dopamine-immunoreactive (DAi) fibers and the effect of the adrenocorticotrophic hormone (ACTH)-(4-9) analog ORG 2766 on this process were investigated 1, 4, 12 and 24 weeks after a unilateral 6-hydroxydopamine (6-OHDA) lesion in the nucleus accumbens (NAc). DAi fibers were almost completely absent 1 ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(96)12498-8

    authors： Vos PE,Steinbusch HW,Van Ree JM

    更新日期：1996-03-22 00:00:00

  • Regional distribution of phosphoinositide-specific phospholipase C activity in rat brain.

    abstract：:The phosphatidylinositol (PI) and phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolytic activities of phosphoinositide-specific phospholipase C (PLC) were measured in membrane and cytosol fractions from 7 discrete areas of the rat brain. Both the PI-PLC and PIP2-PLC specific activities were found to differ significa...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(88)90215-7

    authors： Nishida A,Kaiya H,Tohmatsu T,Banno Y,Wakabayashi S,Nozawa Y

    更新日期：1988-08-01 00:00:00

  • Increasing SMN levels using the histone deacetylase inhibitor SAHA ameliorates defects in skeletal muscle microvasculature in a mouse model of severe spinal muscular atrophy.

    abstract：:Spinal muscular atrophy (SMA), a primarily childhood form of motor neuron disease, is caused by reduced levels of a single, ubiquitously expressed protein: the survival motor neuron (SMN) protein. Low levels of SMN cause motor neuron degeneration but recent reports describe effects of low SMN levels in multiple tissue...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2013.03.052

    authors： Somers E,Riessland M,Schreml J,Wirth B,Gillingwater TH,Parson SH

    更新日期：2013-06-07 00:00:00

  • Protein kinase G linked to dopamine D3 receptors in the dorsal striatum controls dopamine release, ΔFosB expression and locomotor activity after repeated cocaine administration.

    abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2013.02.014

    authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

    更新日期：2013-04-29 00:00:00

  • The posterior insular-opercular cortex: An access to the brain networks of thermosensory and nociceptive processes?

    abstract：:In spite of systematic investigations, the existence of a specific cortex that could encode for the intensities of somatosensory stimuli, including within nociceptive ranges, is still a matter of debate. The present consensus is that pain is expressed in a distributed network made of thalamus, SII, insula, ACC, and, l...

    journal_title：Neuroscience letters

    pub_type： 杂志文章,评审

    doi：10.1016/j.neulet.2018.11.042

    authors： Peyron R,Fauchon C

    更新日期：2019-05-29 00:00:00

  • Stimulation by nerve growth factor of neuropeptide synthesis in the adult rat in vivo: bilateral response to unilateral intraplantar injections.

    abstract：:Unilateral intraplantar injections (1/day for 3 days) of 4 mu g nerve growth factor (NGF) into the rat hindpaw increased the expression of prepro-tachykinin (PPT)- and prepro-calcitonin gene-related peptide (ppCGRP)-mRNA in bilateral L5 dorsal root ganglia (DRGs). This was accompanied by an increase of CGRP-like immun...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(95)12287-7

    authors： Amann R,Sirinathsinghji DJ,Donnerer J,Liebmann I,Schuligoi R

    更新日期：1996-01-26 00:00:00

  • Perception of individual finger forces during multi-finger force production tasks.

    abstract：:The present study examined perception of individual finger forces during multi-finger force production tasks. In an ipsilateral force matching paradigm, 12 healthy subjects were instructed to produce a reference force pre-determined at 30% MVC of involved fingers (varying from 1 to 4 fingers, visual feedback of total ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2006.09.057

    authors： Li S

    更新日期：2006-12-06 00:00:00

  • Statistical learning is lasting and consistent over time.

    abstract：:Implicit detection of statistical regularities is thought to be a ubiquitous facet of cognition; yet, we know little about statistical learning (SL) over time. A recent study showed that visual SL can be observed at 24 h post stimulus (Kim et al., 2009 [14]). Here we sought to obtain a finer-grained picture of visual ...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/j.neulet.2012.04.045

    authors： Arciuli J,Simpson IC

    更新日期：2012-05-31 00:00:00

  • Valinomycin-based K+ selective microelectrodes with low electrical membrane resistance.

    abstract：:A valinomycin-based membrane phase for microelectrodes with relatively low electrical membrane resistances is described. Microelectrodes with tip diameters of about 1 micron exhibit resistances of about 10(10) omega. Extremely high K+ selectivities are obtained, e.g. a rejection of Na+ by a factor of 5000 and of acety...

    journal_title：Neuroscience letters

    pub_type： 杂志文章

    doi：10.1016/0304-3940(87)90153-4

    authors： Ammann D,Chao PS,Simon W

    更新日期：1987-02-24 00:00:00