Abstract:
:It has been generally suggested that chewing produces an enhancing effect on cognitive performance-related aspects of memory by the test battery. Furthermore, recent studies have shown that chewing is associated with activation of various brain regions, including the prefrontal cortex. However, little is known about the relation between cognitive performances affected by chewing and the neuronal activity in specified regions in the brain. We therefore examined the effects of chewing on neuronal activities in the brain during a working memory task using fMRI. The subjects chewed gum, without odor and taste components, between continuously performed two- or three-back (n-back) working memory tasks. Chewing increased the BOLD signals in the middle frontal gyrus (Brodmann's areas 9 and 46) in the dorsolateral prefrontal cortex during the n-back tasks. Furthermore, there were more prominent activations in the right premotor cortex, precuneus, thalamus, hippocampus and inferior parietal lobe during the n-back tasks after the chewing trial. These results suggest that chewing may accelerate or recover the process of working memory besides inducing improvement in the arousal level by the chewing motion.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Hirano Y,Obata T,Kashikura K,Nonaka H,Tachibana A,Ikehira H,Onozuka Mdoi
10.1016/j.neulet.2008.03.033subject
Has Abstractpub_date
2008-05-09 00:00:00pages
189-92issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(08)00316-9journal_volume
436pub_type
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