Abstract:
:Experiments were performed to test several predictions of the hypothesis that activity pattern-dependent changes in intracellular free calcium concentration ([Ca2+]i) might play a role in the translation of altered patterns of neuronal activity into changes in neurotransmitter gene expression. It was shown that (1) the Ca2+ channel blocker cadmium prevented depolarization-induced preprotachykinin-I (PPT-I) gene repression in rat sympathetic neurons; (2) the magnitudes of transient rises in [Ca2+]i were dependent upon the pattern in which a fixed number of depolarizing stimuli were delivered; and (3) stimulation at 10 Hz for 24 h did not repress PPT-I mRNA, while the same number of pulses delivered in 0.2 s bursts of 50 Hz caused a highly significant reduction to 30 +/- 2.5% of control levels.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Hodaie M,Jeevaratnam P,Salter MW,Roach Adoi
10.1016/0304-3940(95)11260-4subject
Has Abstractpub_date
1995-02-13 00:00:00pages
195-8issue
3eissn
0304-3940issn
1872-7972pii
0304394095112604journal_volume
185pub_type
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(92)90033-4
更新日期:1992-03-02 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(87)90401-0
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journal_title:Neuroscience letters
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更新日期:2013-08-29 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(85)90006-0
更新日期:1985-04-09 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2017-10-17 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(96)12712-9
更新日期:1996-06-14 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章,随机对照试验
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abstract::The effect of lesions on nerve growth factor receptor (NGFr) immunoreactivity (IR) in motoneurons within the mature feline trigeminal motor nucleus was investigated. Ten days following complete unilateral retrogasserian trigeminal rhizotomy including transection of the trigeminal motor root, motoneurons within the ips...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90540-a
更新日期:1991-05-27 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2002-08-16 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(02)00328-2
更新日期:2002-06-28 00:00:00
abstract::X-box binding protein 1 (XBP1), a critical gene in the endoplasmic reticulum stress response, is located on chromosome 22q12, which has been linked with bipolar disorders in several studies. Recently, associations have been reported between a polymorphism (-116C --> G) in the promoter region of XBP1, and bipolar disor...
journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.07.044
更新日期:2007-09-07 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.02.068
更新日期:2012-04-11 00:00:00
abstract::Seizures and death are the more important toxic consequences related to cocaine overdose. Some reports have shown that pharmacological manipulations in dopaminergic, serotonergic and noradrenergic systems alter the occurrence of cocaine-induced convulsions and death. Based on this fact, this work was performed to dete...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.03.029
更新日期:2004-05-27 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)11281-z
更新日期:1995-02-15 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90496-8
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.01.065
更新日期:2007-04-12 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2008-07-25 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2000-10-13 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(77)90144-6
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1998-10-23 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2000-08-04 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2004.11.057
更新日期:2005-03-22 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2015.01.033
更新日期:2015-03-04 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(92)90105-g
更新日期:1992-06-22 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(84)90111-3
更新日期:1984-05-18 00:00:00