Estradiol reduces cytochrome c translocation and minimizes hippocampal damage caused by transient global ischemia in rat.

abstract：:The number of active cells in each synchronous firing event in a set of 10 neurosecretory cells in the silkmoth Bombyx mori was estimated from the amplitude and waveform of compound action potentials. One to 10 cells discharged an action potential within a period of 30 ms and one to two or nine to 10 units became acti...

journal_title：Neuroscience letters

authors： Ichikawa T,Imafuku Y,Tawada K

更新日期：1999-04-02 00:00:00

abstract：:Neuropeptide S (NPS) is a recently discovered peptide shown to be involved in regulating arousal and anxiety. NPS receptor (NPSR) mRNA is expressed significantly in the major input and output regions of hippocampal formation, which are critical in the modulation of learning and memory. However, the role of NPS/NPSR sy...

journal_title：Neuroscience letters

authors： Han RW,Yin XQ,Chang M,Peng YL,Li W,Wang R

更新日期：2009-05-08 00:00:00

abstract：:Serotonin transporter (5-HTT) is a key component of the serotonergic neurotransmitter system. Few studies have focused on polymorphisms of the serotonin transporter and antipsychotic response and, in particular, there have so far been no published studies on the association between the serotonin transporter and respon...

journal_title：Neuroscience letters

authors： Wang L,Yu L,He G,Zhang J,Zhang AP,Du J,Tang RQ,Zhao XZ,Ma J,Xuan JK,Xiao Y,Gu NF,Feng GY,Xu MQ,Xing QH,He L

更新日期：2007-02-27 00:00:00

abstract：:Neurotrophic factors maintain and modulate neuron function in adults. We tested the hypothesis that neurotrophic factors rapidly alter intracellular calcium concentrations, thereby affecting neuron excitability. The majority of rat nodose neurons express TrkA, TrkB and TrkC receptor after 1 day in culture. Addition of...

journal_title：Neuroscience letters

authors： Lamb K,Bielefeldt K

更新日期：2003-01-09 00:00:00

abstract：:The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

journal_title：Neuroscience letters

authors： Wijers AA,Been PH,Romkes KS

更新日期：2005-02-10 00:00:00

abstract：:The anatomical distribution of insulin-degrading enzyme (IDE) was studied in normal and Alzheimer's disease (AD) human brains. By use of a monospecific, polyclonal antiserum against the enzyme we identified IDE antigen in multiple cortical and subcortical neurons. Glia did not show IDE immunoreactivity. In AD brains i...

journal_title：Neuroscience letters

authors： Bernstein HG,Ansorge S,Riederer P,Reiser M,Frölich L,Bogerts B

更新日期：1999-03-26 00:00:00

abstract：:Sleep disturbance is common in chronic post-traumatic stress disorder (PTSD). However, prior work has demonstrated that there are inconsistencies between subjective and objective assessments of sleep disturbance in PTSD. Therefore, we investigated whether subjective or objective sleep assessment has greater clinical u...

journal_title：Neuroscience letters

authors： Tahmasian M,Jamalabadi H,Abedini M,Ghadami MR,Sepehry AA,Knight DC,Khazaie H

更新日期：2017-05-22 00:00:00

abstract：:Interactions between emotional stress due to fear and hypovolemic stimuli on vasopressin secretion were studied in rats. Intraperitoneally injected dextran did not significantly change plasma osmolality and arterial blood pressure but increased blood hemoglobin and plasma vasopressin level. An i.v. infused physiologic...

journal_title：Neuroscience letters

authors： Onaka T,Yagi K

更新日期：1990-12-11 00:00:00

abstract：:We assess in mice, the electrophysiological criteria developed in humans and rats in vivo for unmyelinated (C) fibre differentiation into sub-classes, derived from the activity-induced latency increase ("slowing") in response to electrical stimulation during 6 min at 0.25 Hz followed by 3 min at 2 Hz. Fibres are consi...

journal_title：Neuroscience letters

authors： Hoffmann T,De Col R,Messlinger K,Reeh PW,Weidner C

更新日期：2015-04-10 00:00:00

abstract：:Supra-threshold responses of neurons in the primary auditory cortex of the macaque monkey are so complex that the characteristic frequency cannot be determined. By statistical analyses based on analysis of variance and principal component analysis, we demonstrated that the similarity of neurons from penetration perpen...

journal_title：Neuroscience letters

authors： Takahashi T

更新日期：1995-02-24 00:00:00

abstract：:Pitch and duration -- either as written symbols or in auditory form -- are the basic structural properties in tones that form a melodic sequence. From the cognitive perspective, it is still a matter of debate whether, and at which processing stage, these two factors are processed independently or interdependently. The...

journal_title：Neuroscience letters

authors： Neuhaus C,Knösche TR

更新日期：2008-08-15 00:00:00

abstract：:Rapid balance reactions such as compensatory reach to grasp represent important response strategies following unexpected loss of balance. While it has been assumed that early corrective actions arise from subcortical networks, recent research has prompted speculation about the potential role of cortical involvement. W...

journal_title：Neuroscience letters

authors： Bolton DAE,Patel R,Staines WR,McIlroy WE

更新日期：2011-10-24 00:00:00

abstract：:Dopamine D1 and D2 receptors were studied in putamen of post-mortem brains from controls and patients with Alzheimer-type dementia (ATD). A significant reduction in dopamine D2 receptors was observed in ATD, whereas dopamine D1 receptors were unchanged. Neurochemical markers of striatal acetylcholine and GABA-containi...

journal_title：Neuroscience letters

authors： Cross AJ,Crow TJ,Ferrier IN,Johnson JA,Markakis D

更新日期：1984-11-23 00:00:00

abstract：:The clinical efficacy of clozapine in treating schizophrenia may stem from its lack of receptor selectivity. If true, several clozapine-sensitive receptors may be co-expressed by neurons dysfunctional in schizophrenia. To test this hypothesis, neurons from the rat medial prefrontal cortex were acutely isolated and sub...

journal_title：Neuroscience letters

authors： Vysokanov A,Flores-Hernandez J,Surmeier DJ

更新日期：1998-12-24 00:00:00

abstract：:Mutations in DJ-1 cause familial Parkinson's disease (PD). The expression pattern of DJ-1 in the brain remains controversial. In the present study, we used DJ-1 deficient mice as negative controls and examined DJ-1 mRNA expression in mouse brains. In sequential double labeling on the same sections, in situ hybridizati...

journal_title：Neuroscience letters

authors： Xie Z,Zhuang X,Chen L

更新日期：2009-11-20 00:00:00

abstract：:It is well established that the reinforcing effect of drugs of abuse is linked to the mesolimbic dopamine (DA) system. Morphine produces an increase in DA release in the brain, which may provide positive reinforcement contributing to the development of motivational aspects of drug-seeking and maintenance behavior. Sev...

journal_title：Neuroscience letters

authors： Yoon SS,Lee BH,Kim HS,Choi KH,Yun J,Jang EY,Shim I,Kim JA,Kim MR,Yang CH

更新日期：2007-11-20 00:00:00

abstract：:Transgenic mice (Tg2576) that express the Swedish double mutation of human amyloid precursor protein and develop Alzheimer-like beta-amyloid deposits in the aged brain, were used to study the effect of beta-amyloid deposition on expression of both neuronal (nNOS) and inducible nitric oxide synthase (iNOS) in cells sur...

journal_title：Neuroscience letters

authors： Hartlage-Rübsamen M,Apelt J,Schliebs R

更新日期：2001-04-20 00:00:00

abstract：:Following focal brain lesions, complex adaptive processes take place in remote intact areas. The present study examines changes in NMDA (N-methyl-D-aspartate), AMPA ((+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) and kainate receptors following focal photothrombotic ischemic lesions using quantitative...

journal_title：Neuroscience letters

authors： Que M,Schiene K,Witte OW,Zilles K

更新日期：1999-10-01 00:00:00

abstract：:To investigate injury-induced alterations of purinergic P2Y receptor-mediated calcium responses in glial (Müller) cells of the rabbit retina, neural retinae were experimentally detached from the pigment epithelium. The ATP-evoked calcium responses were recorded in the endfeet of glial cells at the vitread surface of r...

journal_title：Neuroscience letters

authors： Uckermann O,Uhlmann S,Weick M,Pannicke T,Francke M,Reichenbach A,Wiedemann P,Bringmann A

更新日期：2003-02-27 00:00:00

abstract：:The neurons located in the mesencephalic ventro-medial tegmentum (VMT) and projecting to the nucleus accumbens, the septum and the frontal cortex were identified by the antidromic activation method. The activity of single VMT cells was extracellularly recorded in Ketamine anaesthetized rats. The effect of the stimulat...

journal_title：Neuroscience letters

authors： Thierry AM,Deniau JM,Feger J

更新日期：1979-12-01 00:00:00

abstract：:Facilitation of synaptic connections between sensory neurons and motor neurons mediating the tail-withdrawal reflex in Aplysia is produced by sensitizing stimuli. These effects can be mimicked by perfusing the pleural and pedal ganglia of a semi-intact preparation with serotonin (5-HT). In addition to the synaptic fac...

journal_title：Neuroscience letters

authors： Walsh JP,Byrne JH

更新日期：1984-11-23 00:00:00

abstract：:Spontaneous action potentials were recorded longitudinally for 4-7 weeks from dissociated rat occipital cortex cells cultured on planar multi-electrode plates, during their development from isolated neurons into synaptically connected neuronal networks. Activity typically consisted of generalized bursts lasting up to ...

journal_title：Neuroscience letters

authors： Van Pelt J,Corner MA,Wolters PS,Rutten WL,Ramakers GJ

更新日期：2004-05-06 00:00:00

abstract：:This study was designed to investigate the effects of honokiol, a neuroprotective agent, on cerebral edema in cerebral ischemia reperfusion (IR) mice and its mechanism of anti-inflammation. Honokiol (0.7-70μg/kg) significantly reduced brain water contents and decreased the exudation of Evans blue dye from brain capill...

journal_title：Neuroscience letters

authors： Zhang P,Liu X,Zhu Y,Chen S,Zhou D,Wang Y

更新日期：2013-02-08 00:00:00

abstract：:In order to analyze the elementary mechanisms underlying caffeine-induced epileptiform discharges, hippocampal slices of guinea pigs were exposed to this drug. When the bath concentration of caffeine exceeded 0.2 mM, periodically occurring paroxysmal depolarizations (PD) in CA3 neurons appeared. They were accompanied ...

journal_title：Neuroscience letters

authors： Moraidis I,Bingmann D,Lehmenkühler A,Speckmann EJ

更新日期：1991-08-05 00:00:00

abstract：:The nerve growth factor (NGF) precursor protein proNGF is the predominant NGF moiety found in the human neocortex and exhibits pro-apoptotic properties when bound to the p75(NTR) neurotrophin receptor in the presence of sortilin, a Vps10p domain trafficking protein. Recently studies have shown that proNGF levels incre...

journal_title：Neuroscience letters

authors： Mufson EJ,Wuu J,Counts SE,Nykjaer A

更新日期：2010-03-08 00:00:00

abstract：:Kainic acid (KA) has been largely used as a neurotoxin, and its axon-sparing effect being repeatedly emphasized, on the basis of anatomical and biochemical data. The present study examines this 'axon-sparing' effect from an electrophysiological point of view and demonstrates that lemniscal fibers retain the capacity t...

journal_title：Neuroscience letters

authors： Peschanski M,Briand A,Poingt JP,Guilbaud G

更新日期：1985-08-05 00:00:00

abstract：:A newly isolated factor from mammalian brain, neurocatin, is shown to increase both the level and release of serotonin in suspensions of synaptosomes isolated from rat brain. Incubation of synaptosomes for 10 min with approximately 20 nM neurocatin resulted in release of about 50% of the total pool of serotonin. Quant...

journal_title：Neuroscience letters

authors： Fernandez-Novoa L,Pastuszko A

更新日期：1991-01-14 00:00:00

abstract：:This is the first report of the presence of nitric oxide synthase (NOS) immunoreactivity and NADPH-diaphorase (NADPH-d) activity in a subpopulation of the intrinsic neurones that innervate the heart. A cytochemical technique to detect NADPH-d and antisera raised against purified rat cerebellar NOS were employed to exa...

journal_title：Neuroscience letters

authors： Hassall CJ,Saffrey MJ,Belai A,Hoyle CH,Moules EW,Moss J,Schmidt HH,Murad F,Förstermann U,Burnstock G

更新日期：1992-08-31 00:00:00

abstract：:Previously, trophic effects of extracts from whole chick embryos and from innervated muscles on cultured muscle cells were described. The present study demonstrated similar effects of extracts from 10-days denervated chick muscles. Extracts from innervated as well as from denervated muscles exsanguinated in vivo with ...

journal_title：Neuroscience letters

authors： Hooisma J,De Krijger J,De Groot DM,Magchielse T,Muijser H

更新日期：1981-02-23 00:00:00

abstract：:To understand the genetic origin of I2020T mutation in the kinase domain of leucine rich repeat kinase 2 (LRRK2), we investigated the original PARK8 Japanese family (Sagamihara family) and a German family (family 32), both of which were found to harbor I2020T as the causal mutation for autosomal dominant familial Park...

journal_title：Neuroscience letters

authors： Ohta E,Hasegawa K,Gasser T,Obata F

更新日期：2007-04-24 00:00:00