Striatal dopamine receptors in Alzheimer-type dementia.

abstract：:The contribution of excitatory inputs to CA1 pyramidal cell death after ischemia was examined using rats with unilateral destruction of CA3 pyramidal cells. Intracerebroventricular injection of L-alpha-kainic acid (KA) was performed before the induction of transient forebrain ischemia. Five days after ischemic insult,...

journal_title：Neuroscience letters

authors： Onodera H,Sato G,Kogure K

更新日期：1986-07-24 00:00:00

abstract：:The potential of nitric oxide for the induction of reactive oxygen species (ROS) has been evaluated in a cerebral synaptosomal fraction. Nitric oxide (NO) was generated using S-nitroso-N-acetylpenicillamine (SNAP). NO stimulated ROS production, assayed using a fluorescent probe. This stimulation was largely inhibited ...

journal_title：Neuroscience letters

authors： Bondy SC,Naderi S

更新日期：1994-02-28 00:00:00

abstract：:Hypoxic encephalopathy is a common cause of neonatal seizures and long-term neurological cognitive deficits. In rats at postnatal days 10-12 (P10-P12), global hypoxia induced spontaneous seizures and chronic brain injury, mimicking clinical aspects of neonatal hypoxia. Synaptic Ras-GTPase activating protein (SynGAP) h...

journal_title：Neuroscience letters

authors： Yang SN,Huang CB,Yang CH,Lai MC,Chen WF,Wang CL,Wu CL,Huang LT

更新日期：2004-11-16 00:00:00

abstract：:Several evidences have pointed to biochemical alterations in some brain structures after experimental Status Epilepticus (SE). Thus, the effects of pilocarpine-induced SE on the glutamate binding in the hippocampus and cortex of Wistar rats were evaluated. Groups of animals were submitted to a 3h SE induced by intrahi...

journal_title：Neuroscience letters

authors： Cunha AO,Mortari MR,Carolino RO,Coutinho-Netto J,Dos Santos WF

更新日期：2007-08-31 00:00:00

abstract：:The potassium conductance (gK) blockers tetraethylammonium (TEA) and 4-aminopyridine (4-AP) strongly excited experimental neuromas that had spontaneous discharge, but had minimal effects on acutely cut nerves and on old, quiescent neuromas. Resting gK apparently moderates hyperexcitability in active neuromas. ...

journal_title：Neuroscience letters

authors： Devor M

更新日期：1983-09-30 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) has strong neurotrophic effects both in vivo and in vitro on various brain neurons. bFGF enhanced the branching of laser beam-damaged axons of primary cultured hippocampal neurons with a suppression of the neurite's re-elongation. Conditioned medium prepared from astrocytes, on th...

journal_title：Neuroscience letters

authors： Miyagawa T,Saito H,Nishiyama N

更新日期：1993-04-16 00:00:00

abstract：:The distribution pattern of sialylated glycoproteins in the hippocampal formation of 9-week-old and 29-month-old rats was examined using Maackia amurensis lectin, specific for Sia alpha2-3Gal, and Sambucus sieboldiana agglutinin specific for Sia alpha2-6Gal(GalNAc), and a monoclonal antibody for a linear homopolymer o...

journal_title：Neuroscience letters

authors： Sato Y,Endo T

更新日期：1999-02-26 00:00:00

abstract：:The combination of ethanol and cocaine is commonly abused by human addicts which has serious clinical consequences. Here, the effects of separately and concurrently administered ethanol and 'binge' cocaine on kappa opioid receptor (KOR) mRNA in the ventral tegmental area (VTA) and nucleus accumbens (NAc) of rats were ...

journal_title：Neuroscience letters

authors： Rosin A,Lindholm S,Franck J,Georgieva J

更新日期：1999-11-05 00:00:00

abstract：:In this study we evaluated oxidative stress (lipid peroxidation and protein oxidation) and thiol redox state [TRS: glutathione (GSH), glutathione disulfide (GSSG), cysteine (CSH), protein (P) thiols (PSH) and protein and non-protein (NP) mixed/symmetric disulfides (PSSR, NPSSR, NPSSC, PSSP)] in hippocampus after penty...

journal_title：Neuroscience letters

authors： Patsoukis N,Zervoudakis G,Panagopoulos NT,Georgiou CD,Angelatou F,Matsokis NA

更新日期：2004-03-04 00:00:00

abstract：:After spinal cord injury (SCI), a complex cascade of pathophysiological processes rapidly damages the nervous tissue. The initial damage spreads to the surrounding tissue by different mechanisms, including oxidative stress. We have recently reported that the induction of metallothionein (MT) protein is an endogenous r...

journal_title：Neuroscience letters

authors： Arellano-Ruiz S,Rios C,Salgado-Ceballos H,Méndez-Armenta M,Del Valle-Mondragón L,Nava-Ruiz C,Altagracia-Martínez M,Díaz-Ruiz A

更新日期：2012-04-11 00:00:00

abstract：:The effects of aging on the stress response of the septo-hippocampal cholinergic neurons was assessed by monitoring hippocampal acetylcholine (ACh) release. Young (3-4 month old) and aged (23-24 month old) male rats were subjected to restraint stress for 1 h. ACh was elevated within 15 min of the onset of restraint st...

journal_title：Neuroscience letters

authors： Mizuno T,Kimura F

更新日期：1997-01-24 00:00:00

abstract：:Previous pharmacokinetics and electrophysiological results indicated an important role of nicotine in the modulation of dopamine transporter (DAT). To elucidate the expression changes of DAT on chronic nicotine and smoke administration, the effects of nicotine and passive cigarette smoke on DAT mRNA expression in the ...

journal_title：Neuroscience letters

authors： Li S,Kim KY,Kim JH,Kim JH,Park MS,Bahk JY,Kim MO

更新日期：2004-06-03 00:00:00

abstract：:This review attempts to explain the symptoms experienced by patients with inflammatory neuropathies by pathophysiological events. The emphasis is not on the primary events that may cause a particular illness but on downstream events taking place in peripheral nerves or muscles. Symptoms that will be discussed include ...

journal_title：Neuroscience letters

authors： Franssen H

更新日期：2015-06-02 00:00:00

abstract：:The effect of a chronic 17 beta-estradiol (10 micrograms, b.i.d.) treatment of 2 weeks to ovariectomized rats was investigated on lateral and medial caudate-putamen dopamine receptors. Dopamine D2 receptors were assayed with [3H]spiperone binding to caudate-putamen homogenates or by autoradiography of forebrain sectio...

journal_title：Neuroscience letters

authors： Falardeau P,Di Paolo T

更新日期：1987-02-10 00:00:00

abstract：:N-Acetylaspartylglutamate (NAAG) is a dipeptide, and has been demonstrated to be a putative neurotransmitter in the brain. We hereby report the toxicity of NAAG in sagittal slices of mouse brain, in vitro, which is prevented by both N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists. Incubation of mouse bra...

journal_title：Neuroscience letters

authors： Pai KS,Ravindranath V

更新日期：1991-05-13 00:00:00

abstract：:The distribution of neurons expressing beta-endorphin immunoreactivity was explored in the brain of adult jerboa during two distinct periods characterizing its reproductive cycle. A large presence of cell bodies displaying beta-endorphin immunoreactivity occured within different parts of the mediobasal hypothalamus al...

journal_title：Neuroscience letters

authors： El Ouezzani S,Tramu G,Magoul R

更新日期：2005-03-11 00:00:00

abstract：:This study was aimed to determine the effect of unilateral hippocampal inactivation on spatial memory retrieval in male and female Wistar rats. Subjects were chronically implanted with a stainless-steel cannula that enabled unilateral intrahippocampal injections of tetrodotoxin, a sodium channel blocker. Rats were tra...

journal_title：Neuroscience letters

authors： Cimadevilla JM,Arias JL

更新日期：2008-07-04 00:00:00

abstract：:The intramedullary axon collateral systems of adult cat spinal alpha-motoneurones were studied with morphological and physiological techniques 12 weeks after peripheral transection of the motor axons. Morphologically, intracellular horseradish peroxidase (HRP) staining showed that the axotomy induced an elimination of...

journal_title：Neuroscience letters

authors： Havton L,Kellerth JO

更新日期：1984-11-23 00:00:00

abstract：:The analgesic effect of kappa partial agonist opioids (i.e. nalbuphine, pentazocine and butorphanol) is significantly greater in women. Recent evidence suggests that this sexual dimorphism may result from a naloxone-sensitive anti-analgesic effect that is activated along with, and summates with, the analgesic effect o...

journal_title：Neuroscience letters

authors： Gear RW,Gordon NC,Miaskowski C,Paul SM,Heller PH,Levine JD

更新日期：2003-11-06 00:00:00

abstract：:An increase in the number of cells undergoing apoptosis was observed in the cingulate sulcus of newborn piglets 48 h after a global hypoxic-ischaemic insult. Apoptotic death was identified morphologically (by light and electron microscopy) and by DNA fragmentation, detected by in situ end labelling. The number of apop...

journal_title：Neuroscience letters

authors： Mehmet H,Yue X,Squier MV,Lorek A,Cady E,Penrice J,Sarraf C,Wylezinska M,Kirkbride V,Cooper C

更新日期：1994-11-07 00:00:00

abstract：:Sex differences in basal extracellular striatal dopamine concentrations in gonadectomized male and female rats have been reported previously. In the current experiment, estrous cycle-dependent variation, sex differences and the effect of gonadectomy on extracellular striatal dopamine concentrations were determined usi...

journal_title：Neuroscience letters

authors： Xiao L,Becker JB

更新日期：1994-10-24 00:00:00

abstract：:Neurons of the rat amygdaloid body were labeled with horseradish peroxidase following its injection into contralateral nuclei of the amygdala. The results strongly suggest that there is a contralateral amygdaloid projection from the basal (dorsal and ventral) nuclei of amygdala; it terminates in the medial, central an...

journal_title：Neuroscience letters

authors： Nitecka L,Amerski L,Narkiewicz O

更新日期：1981-10-01 00:00:00

abstract：:Noradrenaline in the central nervous system plays an important role in regulating physiological functions, and is a key mechanistic component of general anesthesia. The purpose of this present study was to determine if nitrous oxide and xenon modulate noradrenaline release in the cerebral cortex. We performed a series...

journal_title：Neuroscience letters

authors： Yoshida H,Kushikata T,Tose R,Kudo M,Kudo T,Hirota K

更新日期：2010-01-22 00:00:00

abstract：:Exposure to manganese in an industrial or clinical setting can lead to manganism, a neurological disorder with similarities to Parkinson's disease. Although the pathogenetic basis of this disorder is unclear, studies indicate this metal is highly accumulated in astrocytes, suggesting an involvement of these glial cell...

journal_title：Neuroscience letters

authors： Hazell AS,Normandin L,Norenberg MD,Kennedy G,Yi JH

更新日期：2006-04-03 00:00:00

abstract：:The enzyme horseradish peroxidase (HRP) has been applied to the proximal stumps of severed thoracic and lumbar dorsal roots in the turtles Pseudemys scripta elegans and Testudo hermanni. The results obtained confirm the distribution pattern observed with anterograde degeneration techniques. Primary afferent terminal s...

journal_title：Neuroscience letters

authors： Kusuma A,ten Donkelaar HJ

更新日期：1979-10-01 00:00:00

abstract：:Neuropathic pain (NP) is highly disabling, responds poorly to pharmacological treatment, and represents a significant cause of decreased quality of life in patients suffering from spinal cord injury (SCI). In recent years, cell therapy with autologous mesenchymal stromal cells (MSCs) has been considered as a potential...

journal_title：Neuroscience letters

authors： Vaquero J,Zurita M,Rico MA,Aguayo C,Fernández C,Gutiérrez R,Rodríguez-Boto G,Saab A,Hassan R,Ortega C

更新日期：2018-03-23 00:00:00

abstract：:8-OH-DPAT is a 5-HT(1A/7) receptor agonist that enhances behavioral recovery after traumatic brain injury (TBI). This study is a first attempt to decipher whether the benefits induced by 8-OH-DPAT after TBI are mediated by 5-HT(1A) or 5-HT(7) receptors. A single i.p. injection of 8-OH-DPAT (0.5 mg/kg) alone or co-admi...

journal_title：Neuroscience letters

authors： Yelleswarapu NK,Tay JK,Fryer WM,Shah MA,Garcia AN,Cheng JP,Kline AE

更新日期：2012-05-02 00:00:00

abstract：:The mechanism of action of the 'geste antagonistique', or sensory trick, used by patients with dystonic blepharospasm (BSP) to transiently diminish their symptoms is presently unknown. In this paper we examined the effects induced by a sensory trick consisting of finger contact with the face on the electrically induce...

journal_title：Neuroscience letters

authors： Gómez-Wong E,Martí MJ,Cossu G,Fabregat N,Tolosa ES,Valls-Solé J

更新日期：1998-07-24 00:00:00

abstract：:Mood stabilizers are a category of medications used in the management of mood disorders. The mood stabilizing properties of lithium were first reported in 1949 by John Cade, and since then it has been considered the first line treatment for bipolar disorder. Despite presenting more differences than similarities, mood ...

journal_title：Neuroscience letters

authors： Pisanu C,Papadima EM,Del Zompo M,Squassina A

更新日期：2018-03-16 00:00:00

abstract：:Previous studies showed that adenosine receptors of the temporal and frontal cortices were not affected in Alzheimer's disease (AD). Here, we assessed the specific binding of [3H]cyclohexyladenosine to adenosine1 (A1) receptors in hippocampus from AD subjects and age-matched controls. By both particulate membrane and ...

journal_title：Neuroscience letters

authors： Kalaria RN,Sromek S,Wilcox BJ,Unnerstall JR

更新日期：1990-10-16 00:00:00