Relation between symptoms and pathophysiology in inflammatory neuropathies: Controversies and hypotheses.

abstract：:Chronic food restriction increases exploratory behavior, cognitive function, and the rewarding effects of abused drugs. Recently, striatal neuroadaptations that may be involved in these effects were observed. Specifically, D-1 dopamine (DA) receptor agonist challenge produced stronger activation of extracellular signa...

journal_title：Neuroscience letters

authors： Pan Y,Siregar E,Carr KD

更新日期：2006-01-30 00:00:00

abstract：:A possible role of the human cerebellum in the generation of verbs corresponding to presented nouns has been suggested. Previous functional brain imaging studies have compared generation of verbs with the reading of nouns as a measure of verb generation. In the present fMRI study involving healthy human subjects, the ...

journal_title：Neuroscience letters

authors： Frings M,Dimitrova A,Schorn CF,Elles HG,Hein-Kropp C,Gizewski ER,Diener HC,Timmann D

更新日期：2006-11-27 00:00:00

abstract：:Amyloid beta (A beta) is a normal proteolytic fragment of a large precursor protein (beta PP) which undergoes altered conformation, leading to fibril formation. Two main beta PP processing pathways have been described, and we are now reporting the characterization of a third beta PP pathway. A membrane-associated 16 k...

journal_title：Neuroscience letters

authors： Ghiso J,Gardella JE,Liem L,Gorevic PD,Frangione B

更新日期：1994-04-25 00:00:00

abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

journal_title：Neuroscience letters

authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

更新日期：2013-04-29 00:00:00

abstract：:We investigated laminin beta1 expression in the hippocampi of patients with intractable epilepsy and explored the role of laminin beta1 in the pathogenesis of this condition. Fluorescence quantitative PCR, immunofluorescence, immunohistochemistry and Western blotting were used to measure laminin beta1 expression in su...

journal_title：Neuroscience letters

authors： Wu Y,Wang XF,Mo XA,Sun HB,Li JM,Zeng Y,Lin T,Yuan J,Xi ZQ,Zhu X,Zheng JO

更新日期：2008-10-10 00:00:00

abstract：:Copulation was induced in pairs of Aplysia fasciata by adding to the environment a homogenate of the distal portion of the large hermaphroditic duct. Similar effects were not observed in response to an abdominal ganglion homogenate. The data suggest that the duct may secrete a pheromone initiating copulation in Aplysi...

journal_title：Neuroscience letters

authors： Susswein AJ,Benny M

更新日期：1985-09-06 00:00:00

abstract：:Glucose is an important metabolic factor controlling feeding behavior. There is evidence that physiologically relevant glucose sensors reside in the caudal hindbrain. The area postrema (AP) in particular, which has been characterized as a receptive site for the anorectic hormone amylin, may monitor blood glucose level...

journal_title：Neuroscience letters

authors： Riediger T,Schmid HA,Lutz TA,Simon E

更新日期：2002-08-09 00:00:00

abstract：:Retinal progenitor cells (RPCs) are an excellent resource for retinal replacement therapy, because they show enormous potential to differentiate into retinal-specific cell types. While the differentiating influence of serum has long been appreciated, the effects of serum concentration on RPC differentiation into speci...

journal_title：Neuroscience letters

authors： Hu Y,Ji J,Xia J,Zhao P,Fan X,Wang Z,Zhou X,Luo M,Gu P

更新日期：2013-02-08 00:00:00

abstract：:The binding of radioiodinated omega-conotoxin GVIA, a probable Ca channel antagonist, to synaptic plasma membranes of rat brain was examined. Two kinds of specific binding sites were found with apparent dissociation constants of 10 pM and 0.5 nM and maximum binding capacities of 0.5 and 3.4 pmol/mg prot., respectively...

journal_title：Neuroscience letters

authors： Abe T,Koyano K,Saisu H,Nishiuchi Y,Sakakibara S

更新日期：1986-11-11 00:00:00

abstract：:Human low back pain sometimes originates from lumbar facet joints. In human lumbar facet joint inflammation or degeneration, the referred pain is not only expanded into the low back area but also into the leg or foot. The rat L5-L6 facet joint is innervated by the L1-L5 dorsal root ganglia. The presence of brain-deriv...

journal_title：Neuroscience letters

authors： Ohtori S,Takahashi K,Moriya H

更新日期：2002-04-26 00:00:00

abstract：:Alzheimer's disease (AD) is still difficult to be precisely diagnosed in its early stage to date. Establishing of reliable and manageable disease-specific biological markers is required to improve diagnostic accuracy. Based on the hypothesis of cell cycle regulatory failure at the early stage of AD, we tested whether ...

journal_title：Neuroscience letters

authors： Tan M,Wang S,Song J,Jia J

更新日期：2012-05-16 00:00:00

abstract：:TRPA1 agonists cinnamaldehyde (CA) and mustard oil (allyl isothiocyanate=AITC) induce heat hyperalgesia and mechanical allodynia in human skin, and sensitize responses of spinal and trigeminal dorsal horn neurons to noxious skin heating in rats. TRPA1 is also implicated in cold nociception. We presently used behaviora...

journal_title：Neuroscience letters

authors： Tsagareli MG,Tsiklauri N,Zanotto KL,Carstens MI,Klein AH,Sawyer CM,Gurtskaia G,Abzianidze E,Carstens E

更新日期：2010-04-12 00:00:00

abstract：:Interaction of beta-adrenergic and somatostatinergic systems in the hippocampus has not been investigated fully. We studied the influence of DL-isoproterenol (ISO), a beta-adrenergic agonist and DL-propranolol (PRO), a beta-adrenergic blocking agent, on the somatostatinergic system in the rat hippocampus. The short-(5...

journal_title：Neuroscience letters

authors： López-Sañudo S,Arilla E

更新日期：1994-01-03 00:00:00

abstract：:The retinohypothalamic tract (RHT) in the Djungarian hamster Phodopus sungorus was studied using anterograde neuronal transport of cholera toxin subunit B (CTB) following unilateral intraocular injection. A major projection terminates bilaterally in the hypothalamic suprachiasmatic nuclei (SCN). In the anterior ventra...

journal_title：Neuroscience letters

authors： Reuss S,Decker K,Hödl P,Sraka S

更新日期：1994-06-06 00:00:00

abstract：:Using in situ hybridization histochemistry, we have demonstrated that 3 alpha subunit mRNAs of the GABAA receptor are present in different cell populations of the bovine cerebellum. While the alpha 1 mRNA is the most abundant and is present in granule cells, Purkinje cells and stellate/basket cells, the alpha 2 mRNA a...

journal_title：Neuroscience letters

authors： Wisden W,McNaughton LA,Darlison MG,Hunt SP,Barnard EA

更新日期：1989-11-20 00:00:00

abstract：:The involvement of ecto-protein kinase activity in activity-dependent long-term potentiation (LTP) was studied in CA1 neurons of guinea-pig hippocampal slices. Application of 5 microM K-252b, an ecto-protein kinase inhibitor, blocked LTP induced by a theta-burst stimulation (3 bursts composed of 5 pulses at 100 Hz wit...

journal_title：Neuroscience letters

authors： Fujii S,Ito K,Osada H,Hamaguchi T,Kuroda Y,Kato H

更新日期：1995-03-03 00:00:00

abstract：:Glufosinate ammonium, a structural analogue of glutamate, is an active herbicidal ingredient. The neuronal activities of this compound were investigated by use of a microdialysis system that allowed us to measure nitric oxide production in the rat cerebellum in vivo. Kainate (0.3-30 nmol/10 microliter), N-methyl-D-asp...

journal_title：Neuroscience letters

authors： Nakaki T,Mishima A,Suzuki E,Shintani F,Fujii T

更新日期：2000-09-01 00:00:00

abstract：:Total RNA was purified from rat forebrain at different postnatal ages and analyzed by Northern blot using a specific neurotensin receptor RNA probe. The rat neurotensin receptor mRNA was present in high amount during the first 10 days of life. Thereafter, it rapidly decreased and was undetected after 20 days. [3H]neur...

journal_title：Neuroscience letters

authors： Hermans E,Jeanjean AP,Laduron PM,Octave JN,Maloteaux JM

更新日期：1993-07-09 00:00:00

abstract：:Infarct volume and immunoreactivities for trkB and trkC in rat brain were compared at 24 h after 90 min of transient middle cerebral artery occlusion (MCAO) between animal groups with or without neurotrophin-3 (NT-3, 10 microg/250 g animal). Treatment of rat brain with topical application of NT-3 significantly reduced...

journal_title：Neuroscience letters

authors： Zhang WR,Hayashi T,Wang JM,Sasaki C,Sakai K,Warita H,Shiro Y,Suenaga H,Ohmae H,Tsuji S,Itoh T,Nishimura O,Nagasaki H,Abe K

更新日期：1999-12-10 00:00:00

abstract：:The phosphatidylinositol (PI) and phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolytic activities of phosphoinositide-specific phospholipase C (PLC) were measured in membrane and cytosol fractions from 7 discrete areas of the rat brain. Both the PI-PLC and PIP2-PLC specific activities were found to differ significa...

journal_title：Neuroscience letters

authors： Nishida A,Kaiya H,Tohmatsu T,Banno Y,Wakabayashi S,Nozawa Y

更新日期：1988-08-01 00:00:00

abstract：:Prophylaxis of posttraumatic epilepsy will require a detailed knowledge of the epileptogenic pathophysiological processes that follow brain injury. Results from studies of experimental models and human epilepsy highlight alterations in GABAergic interneurons and formation of excessive new excitatory synaptic connectiv...

journal_title：Neuroscience letters

authors： Li H,McDonald W,Parada I,Faria L,Graber K,Takahashi DK,Ma Y,Prince D

更新日期：2011-06-27 00:00:00

abstract：:In this review, we summarize the recent development of positron emission tomography (PET) radioligands for γ-aminobutyric acid A (GABAA) receptors and their potential to measure changes in endogenous GABA levels and highlight the clinical and translational applications of GABA-sensitive PET radioligands. We review the...

journal_title：Neuroscience letters

authors： Andersson JD,Matuskey D,Finnema SJ

更新日期：2019-01-19 00:00:00

abstract：:Assessing the result of conceptual change (i.e., whether an individual has come to correctly understand a science concept) is important in science education, however traditional assessment methods lack objectivity. In this study, permutation entropy (PE) based complexity, a kind of entropy used to quantify the complex...

journal_title：Neuroscience letters

authors： Jin L,Jia H,Li H,Yu D

更新日期：2019-04-23 00:00:00

abstract：:Dibutyrylcytidine 3',5'-cyclic monophosphate (Bt2cCMP) stimulated neurite outgrowth in rat pheochromocytoma PC12 cells in a dose-dependent manner at the dose range from 0.5 mM to 6 mM. About 25% of the cells had neurites in response to 6 mM Bt2cCMP. In contrast with the effect of nerve growth factor (NGF) which increa...

journal_title：Neuroscience letters

authors： Yanagida M,Gohda E,Yamamoto I

更新日期：1990-07-13 00:00:00

abstract：:The present study evaluates the hypotheses that a GABAergic mechanism underlies neurobehavioral sequelae of carotid stenosis and that it can be reversed by carotid revascularization. We used the Rivermead Behavioural Memory Test (RBMT), short interval intracortical inhibition (SICI), intracortical facilitation (ICF), ...

journal_title：Neuroscience letters

authors： Murata K,Fujiki M,Ooba H,Kubo T,Morishige M,Abe T,Ishii K,Kobayashi H,Kiyosue H,Mori H

更新日期：2011-08-18 00:00:00

abstract：:'Clipsin' and other peptide bond hydrolase activities that appear to be integral membrane proteins, including two implicated in the formation of the histological hallmarks of Alzheimer's disease, were assayed in the frontal and parietal cortex from a large (n = 45) series of postmortem human brains. Tissues were extra...

journal_title：Neuroscience letters

authors： Stratmann GC,Webster MT,Francis PT,Procter AW,Bowen DM

更新日期：1992-08-31 00:00:00

abstract：:An immobilisation stress (IS) of 2 h applied to rats at the beginning of the dark period (12 h), i.e. when the animals are more active, induces during the 10 consecutive h a significant rebound (+92%) of paradoxical sleep (PS) while slow-wave sleep state (SWS) is poorly affected. Two h of sleep deprivation, also appli...

journal_title：Neuroscience letters

authors： Rampin C,Cespuglio R,Chastrette N,Jouvet M

更新日期：1991-05-27 00:00:00

abstract：:The role of hippocampal noradrenergic inputs in the modulation of corticosteroid receptor expression has been investigated. Adult male rats were given central 6-hydroxydopamine (6-OHDA) and the expression of hippocampal mineralocorticoid (MR) and glucocorticoid (GR) receptor mRNA was examined after two weeks by in sit...

journal_title：Neuroscience letters

authors： Yau JL,Seckl JR

更新日期：1992-08-17 00:00:00

abstract：:The functional role of non-adrenergic non-cholinergic (NANC) nerves in the autonomic control of the male mini-pig bladder neck was investigated in the present study. Electrical stimulation of muscle strips from male mini-pig bladder neck showed biphasic response with initial phasic contraction followed by post-contrac...

journal_title：Neuroscience letters

authors： Tong YC,Hung YC,Cheng JT

更新日期：1997-04-11 00:00:00

abstract：:Rats subjected to forced oral self-administration of morphine solutions without or in combination with two daily i.p. injections of morphine preferred drinking water when this was offered in addition to morphine solutions. The daily intake of morphine during the terminal phase of self-administration of morphine was 50...

journal_title：Neuroscience letters

authors： Jurna I,Baldauf J,Zenz M

更新日期：1992-04-13 00:00:00