Relation between symptoms and pathophysiology in inflammatory neuropathies: Controversies and hypotheses.

abstract：:It is known that 5HTR2A (rs6311) receptors have high concentration in the cortical layer-5 pyramidal neurons and that these receptors play an important role in the modulation of neurocognitive functions. For example, layer-5 pyramidal neurons mediate cellular level integrative interaction of primary sensory afferent s...

journal_title：Neuroscience letters

authors： Maksimov M,Vaht M,Harro J,Bachmann T

更新日期：2015-01-01 00:00:00

abstract：:Chewing and walking are two oscillatory behaviors performed on an everyday basis. The current study examined the impact chewing at different speeds (i.e. fast, slow, preferred) had on walking performance for fifteen young healthy adults (23.2 + 4.2 years) and fifteen healthy older participants (66.5 + 3.2 years). Chew...

journal_title：Neuroscience letters

authors： Samulski B,Prebor J,Armitano C,Morrison S

更新日期：2019-04-17 00:00:00

abstract：:The present study was undertaken to determine whether the postsynaptic inhibition of motoneurons that occurs following the pontine microinjection of carbachol in the decerebrate cat is due to the activity of Renshaw cells. Thirty-two out of 37 Renshaw cells (86%) were spontaneously active prior to the administration o...

journal_title：Neuroscience letters

authors： Morales FR,Engelhardt JK,Pereda AE,Yamuy J,Chase MH

更新日期：1988-04-12 00:00:00

abstract：:Neuropathic pain (NP) is one of the most common complications after spinal cord injury (SCI), but no protein biomarkers has ever been introduced into clinical diagnosis. Previous studies implicated that toll-like receptor (TLR) 4 played a critical role in the development of NP in animal SCI models. Here, a total of 14...

journal_title：Neuroscience letters

authors： Xu J,E X,Liu H,Li F,Cao Y,Tian J,Yan J

更新日期：2015-05-19 00:00:00

abstract：:Activation of the medial septum (MS) enhances the synchronized firing of pyramidal cells in the hippocampus. At least two distinct mechanisms might be recruited in this process: GABAergic inhibition of hippocampal inhibitory interneurons and cholinergic enhancement of pyramidal cell excitability. In the present study,...

journal_title：Neuroscience letters

authors： Ovsepian SV

更新日期：2006-01-23 00:00:00

abstract：:Release of endogenous polyamines may contribute to neuronal loss in ischemia and related conditions. Primary cortical neurons were exposed to spermine and spermidine and subsequently assayed for [3H]ouabain binding to quantify neuronal loss. Neuronal survival was significantly decreased in the presence of spermine at ...

journal_title：Neuroscience letters

authors： Fahey JM,Pritchard GA,Miller LG

更新日期：1993-10-14 00:00:00

abstract：:The present study examined effects of high altitude exposure, which leads to development of hypoxia, on epiplexus cells associated with the choroid plexus in adult rats. At 2-5 h following exposure, epiplexus cells expressing inducible nitric oxide synthase (iNOS) were commonly observed. Increased expression of comple...

journal_title：Neuroscience letters

authors： Wang D,Kaur C

更新日期：2000-05-19 00:00:00

abstract：:Small-fiber neuropathy was induced in young adult mice by intraperitoneal injection of resiniferatoxin (RTX), a TRPV1 agonist. At day 7, RTX induced significant thermal and mechanical hypoalgesia. At day 28, mechanical and thermal nociception were restored. No nerve degeneration in skin was observed and unmyelinated n...

journal_title：Neuroscience letters

authors： Danigo A,Magy L,Richard L,Sturtz F,Funalot B,Demiot C

更新日期：2014-06-13 00:00:00

abstract：:Estrogen not only modulates nigrostriatal function but also developmental processes in the striatum. Recently, we have demonstrated the presence of the estrogen-synthesizing enzyme aromatase in the developing mouse striatum. This study is concerned with the expression of estrogen receptor-alpha/beta (ER) mRNA in the d...

journal_title：Neuroscience letters

authors： Küppers E,Beyer C

更新日期：1999-12-03 00:00:00

abstract：:Direct exposure of rats to tobacco smoke induces antinociception. We presently investigated if this antinociception is mediated via nicotinic and/or mu-opioid receptors. Adult male rats were surgically implanted with Alzet osmotic minipumps that delivered either saline (control), the nicotinic antagonist mecamylamine,...

journal_title：Neuroscience letters

authors： Simons CT,Cuellar JM,Moore JA,Pinkerton KE,Uyeminami D,Carstens MI,Carstens E

更新日期：2005-12-02 00:00:00

abstract：:A partially purified toxin obtained from the coral reef crab, Lophozozymus pictor was found to be a potent inhibitor of Na+-dependent [14C]-GABA uptake by rat brain synaptosomes. Inhibition was potentiated in the presence of external K+. The I50 value for the toxin was found to be in the region of 10 microgram/ml at a...

journal_title：Neuroscience letters

authors： Tan CH,Abkowitz SJ

更新日期：1979-10-01 00:00:00

abstract：:The effect of antagonists on N-methyl-D-aspartate (NMDA)-induced response was investigated in isolated nucleus tractus solitarii (NTS) neurons freshly isolated from the rat using a conventional pathclamp technique. The NMDA-induced inward current consisted of an initial peak followed by a steady-state component. The c...

journal_title：Neuroscience letters

authors： Nakagawa T,Shirasaki T,Tateishi N,Murase K,Akaike N

更新日期：1990-05-31 00:00:00

abstract：:Bis(7)-tacrine [bis(7)-tetrahydroaminacrine] acts as an AChE inhibitor and also exerts modulatory effects on many ligand-gated ion channels and voltage-gated Ca(2+) and K(+) channels. It has been reported previously that tacrine and some other AChE inhibitors suppressed I(K(A)) in central and peripheral neurons. The p...

journal_title：Neuroscience letters

authors： Nie H,Yu WJ,Li XY,Yuan CH,Pang YP,Li CY,Han YF,Li ZW

更新日期：2007-01-29 00:00:00

abstract：:Previous studies showed that adenosine receptors of the temporal and frontal cortices were not affected in Alzheimer's disease (AD). Here, we assessed the specific binding of [3H]cyclohexyladenosine to adenosine1 (A1) receptors in hippocampus from AD subjects and age-matched controls. By both particulate membrane and ...

journal_title：Neuroscience letters

authors： Kalaria RN,Sromek S,Wilcox BJ,Unnerstall JR

更新日期：1990-10-16 00:00:00

abstract：:The nicotinic acetylcholine receptor (nAChR) antagonist alpha-bungarotoxin (alpha-Btx) binds to two different classes of high affinity binding sites from the Drosophila central nervous system. We have used the bivalent reagent 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) to cross-link 125I-alpha-Btx (M(r) = ...

journal_title：Neuroscience letters

authors： Schloss P,Mayser W,Gundelfinger ED,Betz H

更新日期：1992-09-28 00:00:00

abstract：:The blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB), formed by interactions of tight junctions (TJs) in the endothelia or the choroids plexus, respectively, are important diffusion barriers between systemic circulation and neural tissue of the central nervous system (CNS). Epidemiological incid...

journal_title：Neuroscience letters

authors： Kang HS,Ahn HS,Kang HJ,Gye MC

更新日期：2006-07-10 00:00:00

abstract：:A marked depression of evoked CA1 potentials was observed with the nucleotide analogues a,b-methylene ADP (AOPCP) and adenylimido-diphosphate (AIP) and with 2'-adenosine monophosphate (2'-AMP). While the depression elicited by 5'-nucleotides was completely antagonized by the action of adenosine deaminase, AOPCP and 2'...

journal_title：Neuroscience letters

authors： Lee KS,Schubert P,Emmert H,Kreutzberg GW

更新日期：1981-05-29 00:00:00

abstract：:We aimed to compare immunoreactivity patterns of four different anti-α-syn antibodies in surgical specimens of the gastrointestinal tract of Parkinson disease and control cases. Surgical specimens from stomach, small and large bowel of 6 PD cases and 12 controls were studied. Primary antibodies: anti-α-syn clone KM51,...

journal_title：Neuroscience letters

authors： Aldecoa I,Navarro-Otano J,Stefanova N,Sprenger FS,Seppi K,Poewe W,Cuatrecasas M,Valldeoriola F,Gelpi E,Tolosa E

更新日期：2015-08-18 00:00:00

abstract：:This study investigated the effects of mobile-phone-type radiation on the cerebral activity of seizure-prone animals. When rats transformed into an experimental model of seizure-proneness by acute subconvulsive doses of picrotoxin were exposed to 2 h GSM-modulated 900 MHz radiation at an intensity similar to that emit...

journal_title：Neuroscience letters

authors： López-Martín E,Relova-Quinteiro JL,Gallego-Gómez R,Peleteiro-Fernández M,Jorge-Barreiro FJ,Ares-Pena FJ

更新日期：2006-05-01 00:00:00

abstract：:Thyrotropin releasing hormone (TRH) was applied iontophoretically to single neruones in the rat bulbar reticular formation. TRH excited 41 to 56 cells tested; none were inhibited. Excitation developed slowly and was prolonged, and desensitization often occurred. TRH effects were not correlated with effects of acetylch...

journal_title：Neuroscience letters

authors： Briggs I

更新日期：1979-11-01 00:00:00

abstract：:Female sex hormone, progesterone, in addition to seizure modifying activity is also known as a potential protective agent against various brain injury conditions. Considering the predisposal role of traumatic brain injury (TBI) on developing post-traumatic epilepsy (PTE), the effect of progesterone on post-traumatic e...

journal_title：Neuroscience letters

authors： Ghadiri T,Vakilzadeh G,Hajali V,Khodagholi F

更新日期：2019-09-14 00:00:00

abstract：:Sertindole has been marketed and offered daily clinical practice only for 9 months in our country, so no data has been its QTc prolongation potential. In the present study, we performed a clinical trial to investigate the effects of sertindole on QTc in patients with schizophrenia. The study comprised 21 patients with...

journal_title：Neuroscience letters

authors： Atmaca M,Yavuzkir M,Mermi O,Topuz M,Kanmaz E,Tezcan E

更新日期：2008-09-05 00:00:00

abstract：:The effect of chronic salt loading on urocortin-like immunoreactivity (Ucn-IR) was investigated in the rat hypothalamo-neurohypophysial system. In control rats a few Ucn-IR neurons were observed scattered throughout the supraoptic nucleus (SON) and few in the paraventricular nucleus (PVN). A small number of Ucn-IR fib...

journal_title：Neuroscience letters

authors： Hara Y,Ueta Y,Isse T,Kabashima N,Shibuya I,Hattori Y,Yamashita H

更新日期：1997-05-16 00:00:00

abstract：:We examined liposome-mediated gene transfection of nerve growth factor (NGF) in primary central nervous system cultures. RT-PCR analyses detected increased expression of NGF mRNA one day after liposome-mediated NGF gene transfection. ELISA studies detected large increases in NGF protein in cells and in culture medium ...

journal_title：Neuroscience letters

authors： Yang K,Faustinella F,Xue JJ,Whitson J,Kampfl A,Mu XS,Zhao X,Taglialatela G,Perez-Polo JR,Clifton G

更新日期：1994-12-05 00:00:00

abstract：:This investigation was designed to determine the responses of neurons in the posterior group of nuclei (PO) to tooth pulp stimulation. Eighteen tooth pulp-driven (TPD) neurons were recorded in 9 cats anesthetized with nitrous oxide and halothane, 14 of them in the medial part (POM) and the remainder in the lateral par...

journal_title：Neuroscience letters

authors： Matsumoto N,Sato T,Sawano H,Tochinai A,Suzuki TA

更新日期：1988-11-11 00:00:00

abstract：:Sweetened diets share commonalities with drugs of abuse, but studies comparing behavioral effects of different sweeteners are lacking. Common table sugar produces rewarding and withdrawal effects in planarians. We postulated that Splenda and Equal would produce similar responses and used a tetrad of behavioral assays ...

journal_title：Neuroscience letters

authors： Ouyang K,Nayak S,Lee Y,Kim E,Wu M,Tallarida CS,Rawls SM

更新日期：2017-01-01 00:00:00

abstract：:Almost all mechanoreceptive neurons in the cortical taste area (CTA) of the rat had receptive fields (RFs) in the oral cavity, except for a few neurons at the border with the primary somatosensory area that had RFs on the contralateral rhinarium or upper lip. About one-third of the mechanoreceptive neurons with RFs in...

journal_title：Neuroscience letters

authors： Ogawa H,Wang XD

更新日期：2002-04-05 00:00:00

abstract：:Fe65 is a brain enriched multi domain adaptor protein involved in diverse cellular functions. One of its binding partners is the amyloid-β (Aβ) precursor protein (APP), which after sequential proteolytic processing by secretases gives rise to the Alzheimer's Aβ peptide. Fe65 binds to the APP intracellular domain (AICD...

journal_title：Neuroscience letters

authors： Koistinen NA,Bacanu S,Iverfeldt K

更新日期：2016-02-02 00:00:00

abstract：:The mesencephalic trigeminal nucleus contains cell bodies of primary somatic sensory neurons that innervate the head region. The neurons resemble dorsal root ganglion cells but a striking difference is the presence of synaptic boutons in the nucleus. The present report demonstrates with anterograde tracers, the existe...

journal_title：Neuroscience letters

authors： Buisseret-Delmas C,Pinganaud G,Compoint C,Buisseret P

更新日期：1997-07-04 00:00:00

abstract：:A compound action potential of short latency was recorded from the ganglion mesencephali extrolaterale in response to both the fish's own electric organ discharge and electric stimulation of the whole fish or a branch of the posterior lateral line nerve. The time difference between the response in the nerve, 16 mm fro...

journal_title：Neuroscience letters

authors： Enger PS,Libouban S,Szabo T

更新日期：1976-05-01 00:00:00