Inflammatory pain mediated by a phenotypic switch in brain-derived neurotrophic factor-immunoreactive dorsal root ganglion neurons innervating the lumbar facet joints in rats.

abstract：:This study evaluated the immediate and persistent behavioral and molecular consequences (i.e., emotional signs emerging during withdrawal and signs of neurotoxicity) following adolescent morphine exposure with a sex perspective. Basally, and prior to drug treatment, adolescent female rats showed smaller body weight an...

journal_title：Neuroscience letters

authors： Jiménez-Romero F,Bis-Humbert C,García-Fuster MJ

更新日期：2020-01-10 00:00:00

abstract：:Dinucleotide repeat polymorphism has been observed in the promoter of the alpha-synuclein (alpha-SYN)/NAC precursor protein (NACP) gene. Alpha-SYN/NACP allele 3 (described by Xia et al. (Ann. Neurol., 40 (1996) 207), equivalent to allele 1 described by Krüger et al. (Ann. Neurol. 45 (1999) 611) is reported to be signi...

journal_title：Neuroscience letters

authors： Izumi Y,Morino H,Oda M,Maruyama H,Udaka F,Kameyama M,Nakamura S,Kawakami H

更新日期：2001-03-09 00:00:00

abstract：:A new method for on-line analysis of in vivo differential normal pulse voltammograms is reported. They are fitted by least squares to an expression describing the contribution of different electroactive species and the baseline. Its validity for resolving ascorbate (AA), dopamine (DA) and DOPAC signals is evidenced by...

journal_title：Neuroscience letters

authors： Gonzalez-Mora JL,Sanchez-Bruno JA,Mas M

更新日期：1988-03-21 00:00:00

abstract：:Adenosine and AMP (5'-adenosine monophosphate) applied by microiontophoresis produced depression of neuronal firing rates in cerebral cortex. A number of antidepressant drugs including examples which are known not to affect noradrenaline uptake systems, potentiated the depressant purine effects. Noradrenaline response...

journal_title：Neuroscience letters

authors： Stone TW,Taylor DA

更新日期：1979-01-01 00:00:00

abstract：:Recent evidence has suggested that down-regulation of somatostatin (SST) expression in the human brain during early stages of aging leads to an elevation in the steady-state levels of Abeta and therefore may be involved in Alzheimer's disease (AD) progression. We hypothesized that alterations in the SST gene might alt...

journal_title：Neuroscience letters

authors： Xue S,Jia L,Jia J

更新日期：2009-11-13 00:00:00

abstract：:We have previously demonstrated that differences in neuropathic pain-like behaviors after sciatic nerve injury genetically maps to the major histocompatibility complex (MHC) in rats carrying RT1(c) or RT1(av1) haplotypes on the Piebald Virol Glaxo (PVG) background. In order to further explore the genetic contribution ...

journal_title：Neuroscience letters

authors： Dominguez CA,Li L,Lidman O,Olsson T,Wiesenfeld-Hallin Z,Piehl F,Xu XJ

更新日期：2008-09-19 00:00:00

abstract：:Previous studies established that glutamate decarboxylase (GAD) is present in the brain of higher vertebrates in two forms composed of the homodimeric association of two subunits 59 and 63 kDa, respectively, that were found to be structurally related. We have performed quantitative comparative immunoblotting of whole ...

journal_title：Neuroscience letters

authors： Henry S,Tappaz M

更新日期：1991-10-14 00:00:00

abstract：:Enteric glial cells are increasingly acknowledged as important partners of enteric neurons in the control of gastrointestinal function. They share morphological features and expression of antigenic markers with astrocytes of the central nervous system. Recently, aldehyde dehydrogenase 1 family member L1 (Aldh1L1) has ...

journal_title：Neuroscience letters

authors： Boesmans W,Rocha NP,Reis HJ,Holt M,Vanden Berghe P

更新日期：2014-04-30 00:00:00

abstract：:The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic s...

journal_title：Neuroscience letters

authors： Landrieu P,Goffinet A

更新日期：1979-06-01 00:00:00

abstract：:The binding site for 1,4-benzodiazepines in the brain is part of the hetero-oligomeric gamma-aminobutyric acid (GABA)A receptor complex which regulates a chloride ion channel. The presence of the gamma 2 subunit in the complex is necessary for the binding of benzodiazepines to their binding site. This study demonstrat...

journal_title：Neuroscience letters

authors： Karle J,Witt MR,Nielsen M

更新日期：1995-12-29 00:00:00

abstract：:Increasing evidence shows that inflammation may contribute to the pathophysiology of depression. Apigenin, one type of natural flavone, has a number of biological actions including anti-inflammatory effects. Although it has potential antidepressant activity in a chronic mild stress model, the mechanisms of antidepress...

journal_title：Neuroscience letters

authors： Li R,Zhao D,Qu R,Fu Q,Ma S

更新日期：2015-05-06 00:00:00

abstract：:A digoxigenin-labeled antisense 42-mer oligonucleotide was used for the localization of the dopamine D2 receptor mRNA in the rat brain. The digoxigenin label was identified with alkaline phosphatase conjugated sheep-anti-digoxigenin. In good analogy with the known terminal fields of the dopaminergic system, various nu...

journal_title：Neuroscience letters

authors： Brouwer N,Van Dijken H,Ruiters MH,Van Willigen JD,Ter Horst GJ

更新日期：1992-08-17 00:00:00

abstract：:The chitinase 3-like 1 (CHI3L1) gene, a cellular survival factor against several environmental and psychosocial stresses, has been sown to be more highly expressed in the hippocampus and prefrontal cortex of patients with schizophrenia than unaffected individuals. We recently reported a significant association between...

journal_title：Neuroscience letters

authors： Yamamori H,Hashimoto R,Ohi K,Yasuda Y,Fukumoto M,Kasahara E,Sekiyama A,Umeda-Yano S,Okada T,Iwase M,Kazui H,Ito A,Takeda M

更新日期：2012-04-04 00:00:00

abstract：:Erythropoietin (EPO) and its specific receptor (EPOR) have been proposed to act as an endogenous system protecting against neuronal injury and neurodegeneration. We measured EPO in cerebrospinal fluid (CSF) of patients with neurodegenerative diseases, and tested for a correlation with an established biomarker of neuro...

journal_title：Neuroscience letters

authors： Brettschneider J,Widl K,Ehrenreich H,Riepe M,Tumani H

更新日期：2006-09-01 00:00:00

abstract：:A compound action potential of short latency was recorded from the ganglion mesencephali extrolaterale in response to both the fish's own electric organ discharge and electric stimulation of the whole fish or a branch of the posterior lateral line nerve. The time difference between the response in the nerve, 16 mm fro...

journal_title：Neuroscience letters

authors： Enger PS,Libouban S,Szabo T

更新日期：1976-05-01 00:00:00

abstract：:The thickness of the dura mater was obtained from ultrasound probes on the skull and fast Fourier transform-Cepstrum through a probability process at various intracranial pressures (ICP), measured with pressure transducers, in 12 anesthetized dogs. There was a constant relationship between changes in thickness (micron...

journal_title：Neuroscience letters

authors： Kuchiwaki H,Inao S,Ishii N,Ogura Y,Sakuma N

更新日期：1995-09-22 00:00:00

abstract：:Imaging and lesion studies suggest that the cerebellum is involved in the self-generation of timed motor responses. Using repetitive transcranial magnetic stimulation (rTMS), we studied the effects of transient disruption of the lateral or medial cerebellum on a paced-finger-tapping task (PFT). Results show greater va...

journal_title：Neuroscience letters

authors： Théoret H,Haque J,Pascual-Leone A

更新日期：2001-06-22 00:00:00

abstract：:The rostral ventromedial medulla (RVM) has been established as part of a descending pain-modulatory pathway. While the RVM has been shown to modulate homosegmental nociceptive reflexes such as tail flick or hindpaw withdrawal, it is not known what role the RVM plays in modulating the magnitude of multisegmental, organ...

journal_title：Neuroscience letters

authors： Jinks SL,Carstens EE,Antognini JF

更新日期：2007-10-22 00:00:00

abstract：:Neurons of the medial septum-nucleus of the diagonal band of Broca (vertical limb) area were identified as septo-hippocampal neurons by antidromic electrical activation in anesthetized rats. A large majority of these presumably cholinergic neurons could be excited by the iontophoretic application of acetylcholine or c...

journal_title：Neuroscience letters

authors： Dutar P,Lamour Y,Jobert A

更新日期：1983-12-23 00:00:00

abstract：:Early onset generalized dystonia is a dominantly inherited movement disorder caused by neuronal dysfunction without an apparent loss of neurons. The same single mutation (GAG deletion) causes most cases and results in loss of a glutamic acid (E) in the carboxy terminal region of torsinA (Delta302/303). To model the ne...

journal_title：Neuroscience letters

authors： Kock N,Allchorne AJ,Sena-Esteves M,Woolf CJ,Breakefield XO

更新日期：2006-03-13 00:00:00

abstract：:We developed a novel procedure for efficient mutagenesis of zebrafish using a DNA cross-linking agent 4,5',8-trimethylpsoralen (TMP), which is known to frequently induce small deletions in Escherichia coli and Caenorhabditis elegans. A specific-locus test and pilot screenings indicated that the TMP mutagenesis procedu...

journal_title：Neuroscience letters

authors： Ando H,Mishina M

更新日期：1998-03-13 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00

abstract：:Recently, the gene called DAAO was reported to be associated with schizophrenia in the French Canadian populations. Here, we report a result obtained in the study of our large collection of 547 schizophrenia cases and 536 controls in the Chinese population. Six single-nucleotide polymorphisms (SNPs) were genotyped at ...

journal_title：Neuroscience letters

authors： Liu X,He G,Wang X,Chen Q,Qian X,Lin W,Li D,Gu N,Feng G,He L

更新日期：2004-10-21 00:00:00

abstract：:Intrathecal (i.t.) administration of substance P in the awake rat decreases reaction time (RT) in the tail flick test. In the anaesthetized rat, noxious thermal stimulation of the tail (by immersion of tip in water at 55 degrees C) also decreases RT; this effect is blocked by a substance P antagonist. The present stud...

journal_title：Neuroscience letters

authors： Cridland RA,Henry JL

更新日期：1989-07-31 00:00:00

abstract：:In the present study we sought to determine whether the strain difference in fear reactivity between spontaneously hypertensive rats (SHR) and strain-matched WKY controls might be related to adrenocortical function. SHR and WKY were subjected to adrenalectomy prior to classical fear conditioning. Adrenal cortical ster...

journal_title：Neuroscience letters

authors： Sakaguchi A,LeDoux JE,Sved AF,Reis DJ

更新日期：1984-04-20 00:00:00

abstract：:Functionally active N-methyl-D-aspartate (NMDA) receptors on cat medullary respiratory neurones were revealed by local iontophoretic application of DL-2-amino-7-phosphonoheptanoic acid (AP7). Blockade of NMDA receptors by systemic administration of NMDA antagonists (MK-801, phencyclidine, ketamine, AP7) in vagotomized...

journal_title：Neuroscience letters

authors： Foutz AS,Champagnat J,Denavit-Saubié M

更新日期：1988-05-03 00:00:00

abstract：:The nasal cavity of vertebrates contains a variety of xenobiotic metabolizing enzymes that possess a broad range of substrate specificity ranging from metabolism of drugs, carcinogens, and steroid hormones, to dietary components and environmental pollutants. This investigation sought to localize the cellular expressio...

journal_title：Neuroscience letters

authors： Green N,Weech M,Walters E

更新日期：2005-03-03 00:00:00

abstract：:Pain-related evoked potentials (PREP) is an established electrophysiological method to evaluate the signal transmission of electrically stimulated A-delta fibres. Although prerequisite for its clinical use, test-retest-reliability and side-to-side differences of bilateral stimulation in healthy subjects have not been ...

journal_title：Neuroscience letters

authors： Özgül ÖS,Maier C,Enax-Krumova EK,Vollert J,Fischer M,Tegenthoff M,Höffken O

更新日期：2017-04-24 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a common disorder of cognitive functions in aged patients following anesthesia and surgery. α7-nicotinic acetylcholine receptors (α7-nAChR) plays a regulatory role in cognitive processes and is involved in cognitive deficits. This study aims to observe the effect of electr...

journal_title：Neuroscience letters

authors： Liu PR,Zhou Y,Zhang Y,Diao S

更新日期：2017-10-17 00:00:00

abstract：:Diabetic polyneuropathy is a common and disturbing complication of diabetes mellitus, presenting patients and caregivers with a substantial disease burden. Emerging mechanisms which are underlying diabetes may provide novel pathways to understand diabetic polyneuropathy (DPN). Specifically, non-coding RNA molecules co...

journal_title：Neuroscience letters

authors： Meydan C,Üçeyler N,Soreq H

更新日期：2020-07-13 00:00:00