N-methyl-D-aspartate (NMDA) receptors control respiratory off-switch in cat.

abstract：:The morphology of single saccular afferents was studied by the intracellular horseradish peroxidase (HRP) method. Four neurons were sufficiently stained to allow reconstruction of their axonal arborizations. The main axon of these neurons bifurcated into an ascending and a descending branch at the level of the lateral...

journal_title：Neuroscience letters

authors： Imagawa M,Graf W,Sato H,Suwa H,Isu N,Izumi R,Uchino Y

更新日期：1998-01-16 00:00:00

abstract：:In order to study the influence of curare and atropine on the gamma-aminobutyric acid (GABA)-evoked chloride current, we have investigated cultures of hippocampal and septal region neurons from embryonic rats (E18). The neurons were cultured under the trophic influence of spatially separated astrocytes in serum-free m...

journal_title：Neuroscience letters

authors： Siebler M,Köller H,Schmalenbach C,Müller HW

更新日期：1988-11-11 00:00:00

abstract：:Extracellular dopamine and noradrenaline concentrations in the medial prefrontal cortex were determined using online microdialysis in freely moving rats during classical appetitive or aversive conditioning to a contextual conditioned stimulus (CS). As CS we used placement in a Skinner box where either foot shocks or f...

journal_title：Neuroscience letters

authors： Feenstra MG,Teske G,Botterblom MH,De Bruin JP

更新日期：1999-09-17 00:00:00

abstract：:We evaluated the effect of cabergoline on superoxide anion production by rat microglial cells using a 2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1, 2-a]pyrazin-3-one-dependent chemiluminescence assay. Cabergoline dose-dependently inhibited superoxide anion production by microglial cells stimulated with phorbol my...

journal_title：Neuroscience letters

authors： Yoshida T,Tanaka M,Suzuki Y,Sohmiya M,Okamoto K

更新日期：2002-09-13 00:00:00

abstract：:Alzheimer' disease is a neurodegenerative disorder characterized by the misfolding and aggregation of amyloid β (Aβ). This process is influenced through supply of cholesterol via apolipoproteins to neurons. In the present study, we used the transgenic Caenorhabditis elegans strain CL2006, which expresses Aβ1-42 under ...

journal_title：Neuroscience letters

authors： Regitz C,Wenzel U

更新日期：2014-07-25 00:00:00

abstract：INTRODUCTION:Several lines of evidence support an immunologic involvement in obsessive-compulsive disorder (OCD): the increased prevalence of OCD in patients with rheumatic fever (RF), and the aggregation of obsessive-compulsive spectrum disorders among relatives of RF probands. Tumor necrosis factor alpha is a proinfl...

journal_title：Neuroscience letters

authors： Hounie AG,Cappi C,Cordeiro Q,Sampaio AS,Moraes I,Rosário MC,Palácios SA,Goldberg AC,Vallada HP,Machado-Lima A,Nakano E,Kalil J,Pauls D,Pereira CA,Guilherme L,Miguel EC

更新日期：2008-09-12 00:00:00

abstract：:In the present study, we tried to examine whether the 2-deoxy-D-[14C]glucose (2-DG) technique is useful to investigate the metabolic activity of fetal rat brain in the maternal uterus. The result shows that metabolic mapping of the fetal brain was clearly obtained by means of the 2-DG technique. ...

journal_title：Neuroscience letters

authors： Morimoto A,Imai-Matsumura K,Murakami N

更新日期：1990-03-26 00:00:00

abstract：:The effect of calcium on the biogenic amine level and distribution in the mouse brain was investigated by a histochemical method using a microscopic photometer (Pl, Nikon). Histochemical fluorescence intensities in the corpus striatum and cortex cerebri regions were significantly increased by the intraventricular admi...

journal_title：Neuroscience letters

authors： Sutoo D,Akiyama K

更新日期：1986-08-15 00:00:00

abstract：:We studied axonal branching of 14 parabrachial nucleus neurons, activated antidromically from 2 of the 3 stimulation sites, i.e. the ipsi- and contralateral thalamic taste area (TTAs) and the ipsilateral central nucleus of the amygdala (CA). Making use of antidromic latencies, collision times and refractory periods at...

journal_title：Neuroscience letters

authors： Hayama T,Ogawa H

更新日期：1987-12-16 00:00:00

abstract：:Activity-dependent neuroprotective protein (ADNP) is a highly conserved vasoactive intestinal peptide (VIP) responsive gene that is expressed abundantly in the brain and in the body and is essential for brain formation and embryonic development. Since, VIP exhibits sexual dimorphism in the hypothalamus, the potential ...

journal_title：Neuroscience letters

authors： Furman S,Hill JM,Vulih I,Zaltzman R,Hauser JM,Brenneman DE,Gozes I

更新日期：2005-01-03 00:00:00

abstract：:The phosphatidylinositol (PI) and phosphatidylinositol 4,5-bisphosphate (PIP2) hydrolytic activities of phosphoinositide-specific phospholipase C (PLC) were measured in membrane and cytosol fractions from 7 discrete areas of the rat brain. Both the PI-PLC and PIP2-PLC specific activities were found to differ significa...

journal_title：Neuroscience letters

authors： Nishida A,Kaiya H,Tohmatsu T,Banno Y,Wakabayashi S,Nozawa Y

更新日期：1988-08-01 00:00:00

abstract：:Ca2+ signals regulate most aspects of animal cell life. They are of particular importance to the nervous system, in which they regulate specific functions, from neuronal development to synaptic plasticity. The homeostasis of cell Ca2+ must thus be very precisely regulated: in all cells Ca2+ pumps transport it from the...

journal_title：Neuroscience letters

authors： Calì T,Brini M,Carafoli E

更新日期：2018-01-10 00:00:00

abstract：:It has recently been shown that noise can improve the detection of stimuli in several sensory modalities. We herein investigated whether visual contrast detection sensitivity can be improved by adding a certain amount of noise. The contrast detection thresholds of a light changing brightness periodically were measured...

journal_title：Neuroscience letters

authors： Sasaki H,Todorokihara M,Ishida T,Miyachi J,Kitamura T,Aoki R

更新日期：2006-11-13 00:00:00

abstract：:The modification of tuning properties in the cochlea has been studied by means of tuning curves from auditory nerve fibers in kittens of various ages. Comparison of tuning curves of three characteristic frequencies (CF) shows that the tuning of high CF units tends to approach adult values by the end of the second post...

journal_title：Neuroscience letters

authors： Romand R

更新日期：1983-03-14 00:00:00

abstract：:Painful vincristine (VCR) neuropathy is a frequent and dose-limiting problem in cancer treatment. Here, we investigated how pain behavior is modulated in mice lacking the serotonin transporter (5-HTT-/- mice) after inducing neuropathy by intraperitoneal injections of VCR. We used standard tests for evoked pain, high p...

journal_title：Neuroscience letters

authors： Hansen N,Uçeyler N,Palm F,Zelenka M,Biko L,Lesch KP,Gerlach M,Sommer C

更新日期：2011-05-16 00:00:00

abstract：:We used an intracellular microelectrode technique to study the mechanisms of action of two isoforms (human and rat) of calcitonin gene-related peptide (CGRP) on the evoked and spontaneous quantal secretion of acetylcholine (ACh) in mouse diaphragm motor synapses. Recordings of miniature endplate potentials (MEPPs) and...

journal_title：Neuroscience letters

authors： Gaydukov AE,Bogacheva PO,Balezina OP

更新日期：2016-08-15 00:00:00

abstract：:Recently, research on lateralized event related potentials (ERPs) in response to irrelevant distractors has revealed that angry but not happy schematic distractors capture spatial attention. Whether this effect occurs in the context of the natural expression of emotions is unknown. To fill this gap, observers were ask...

journal_title：Neuroscience letters

authors： Burra N,Coll SY,Barras C,Kerzel D

更新日期：2017-01-10 00:00:00

abstract：:Several studies demonstrated that Diabetes mellitus (DM) enhances the risk for Alzheimer's disease (AD). Although hyperglycemia and perturbed function of insulin signaling have been proposed to contribute to AD pathogenesis, the molecular mechanisms behind this association is not clear yet. Seladin-1 is an enzyme cata...

journal_title：Neuroscience letters

authors： Kazkayasi I,Ismail MA,Parrado-Fernandez C,Björkhem I,Pekiner C,Uma S,Cedazo-Minguez A,Burul-Bozkurt N

更新日期：2016-10-28 00:00:00

abstract：:Recent evidence indicates that the N-methyl-D-aspartate (NMDA) receptor-channel complex contains a glycine subunit whose activation may be necessary for channel operation. It has been previously shown that stimulation of the NMDA receptor leads to an increase in intracellular ionic Ca2+ [( Ca2+]i); therefore, we exami...

journal_title：Neuroscience letters

authors： Oliver MW,Shacklock JA,Kessler M,Lynch G,Baimbridge KG

更新日期：1990-07-03 00:00:00

abstract：:Repeated treatment with dl-pentazocine (5-10 mg/kg i.p.), but not d-methamphetamine (4.8 mg/kg i.p.), twice daily for 8 days diminished the specific [3H]1,3-di-o-tolylguanidine (DTG) binding to the haloperidol-sensitive sigma sites in rat striatum and hippocampus. Either drug failed to cause any changes in the binding...

journal_title：Neuroscience letters

authors： Shirayama Y,Nishikawa T,Takahashi K

更新日期：1994-01-03 00:00:00

abstract：:Acetylcholine, synthesized in the cytoplasm of cholinergic neurons by choline acetyltransferase (ChAT), is packaged in synaptic vesicles by vesicular acetylcholine transporter (VAChT). The entire VAChT gene has been reported to be located within the first intron of the ChAT gene. In order to examine whether or not ChA...

journal_title：Neuroscience letters

authors： Matsuura J,Ajiki K,Ichikawa T,Misawa H

更新日期：1997-10-31 00:00:00

abstract：:X-box binding protein 1 (XBP1), a critical gene in the endoplasmic reticulum stress response, is located on chromosome 22q12, which has been linked with bipolar disorders in several studies. Recently, associations have been reported between a polymorphism (-116C --> G) in the promoter region of XBP1, and bipolar disor...

journal_title：Neuroscience letters

authors： Hou SJ,Yen FC,Cheng CY,Tsai SJ,Hong CJ

更新日期：2004-09-02 00:00:00

abstract：:Mammalian neurons express the neural intermediate filament protein neurofilament (NF). In the retina, NFs have been detected primarily in the axons and processes of retinal ganglion and horizontal cells. We found an amacrine cell type that was immunolabeled with an antibody against SMI32, a non-phosphorylated epitope ...

journal_title：Neuroscience letters

authors： Lim EJ,Kim IB,Oh SJ,Chun MH

更新日期：2007-09-13 00:00:00

abstract：:New psychoactive substances (NPSs), i.e., newly designed substances with chemical residues that are slightly different from those of known psychoactive substances, have been emerging since the late 2000s, and social problems related to the use of these substances are increasing globally. Two such NPSs are 4-chloro-2,5...

journal_title：Neuroscience letters

authors： Cha HJ,Jeon SY,Jang HJ,Shin J,Kim YH,Suh SK

更新日期：2018-05-29 00:00:00

abstract：:The synucleins are a family of small proteins expressed in nervous tissue, which have been implicated in neurodegeneration. Using single strand conformation polymorphism analysis we screened for polymorphisms and mutations in the gene encoding human persyn, a recently discovered member of the synuclein family, in cont...

journal_title：Neuroscience letters

authors： Flowers JM,Leigh PN,Davies AM,Ninkina NN,Buchman VL,Vaughan J,Wood NW,Powell JF

更新日期：1999-10-15 00:00:00

abstract：:A previous study of brain activation in normal subjects during a phonological (Phonemes) task and a lexical semantic (Words) task using positron-emission tomography [3] is complemented by new data after a method for image realignment was applied [17]. The pattern of cerebral blood flow increases associated with Words ...

journal_title：Neuroscience letters

authors： Démonet JF,Price C,Wise R,Frackowiak RS

更新日期：1994-11-21 00:00:00

abstract：:To light illumination retinal amacrine cells respond with graded depolarization accompanied by a spike discharge. It has been assumed that the graded depolarization is produced solely by the excitatory synaptic inputs from bipolar cells. Here we demonstrate that a tetrodotoxin (TTX)-sensitive persistent current also c...

journal_title：Neuroscience letters

authors： Watanabe S,Satoh H,Koizumi A,Takayanagi T,Kaneko A

更新日期：2000-01-07 00:00:00

abstract：:Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology. After the development of first Abeta plaques in transgenic mice brain, cortical mRNA and protein levels of IDE were significan...

journal_title：Neuroscience letters

authors： Vepsäläinen S,Hiltunen M,Helisalmi S,Wang J,van Groen T,Tanila H,Soininen H

更新日期：2008-06-20 00:00:00

abstract：:Transmeatal cochlear laser (TCL) treatment has recently been proposed as a therapeutic procedure for cochlear dysfunction such as chronic cochlear tinnitus or sensorineural hearing loss. The aim of this study was to investigate whether TLC has any influence on the central nervous system using functional MRI with healt...

journal_title：Neuroscience letters

authors： Siedentopf CM,Ischebeck A,Haala IA,Mottaghy FM,Schikora D,Verius M,Koppelstaetter F,Buchberger W,Schlager A,Felber SR,Golaszewski SM

更新日期：2007-01-16 00:00:00

abstract：:Proton-induced Na+ currents (INa(H] were measured in precursor cells from chick dorsal root ganglia with whole-cell patch-clamp recording. Precursor cells were isolated using the method of Rohrer et al. (EMBO. J., 4 (1985) 1709-1714) and fast pH changes were applied with a technique developed by Davies et al. (J. Phys...

journal_title：Neuroscience letters

authors： Gottmann K,Dietzel ID,Lux HD,Ruedel C

更新日期：1989-04-24 00:00:00